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公开(公告)号：US20130100455A1
公开(公告)日：2013-04-25
申请号：US13437697
申请日：2012-04-02
IPC分类号： G01B9/02
CPC分类号： G01N33/4833 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/6852 , G01B9/02 , G01B9/02027 , G01B9/02049 , G01B9/02064 , G01B9/02087 , G01B9/02091 , G01B9/04 , G01N21/25 , G01N21/27 , G01N21/4795 , G01N21/6458 , G01N21/6486 , G01N23/046 , G01N2021/1765 , G01N2223/419 , G02B21/0028 , G02B23/2423 , G02B23/243 , G02B23/2461 , G02B23/2476
摘要： Exemplary method, apparatus and arrangement can be provided for obtaining information associated with a sample such as a portion of an anatomical structure. The information can be generated using first data, which can be based on a signal obtained from a location on the sample, and second data, where the second data can be obtained by combining a second signal received from the sample with a third reference signal. An image of a portion of the sample can also be generated based on the information. For example, the first data can be associated with spectral encoding microscopy data, and the second data can be associated with optical coherence tomography data.
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22.发明申请Apparatus for Obtaining Information For A Structure Using Spectrally-Encoded Endoscopy Techniques and Methods for Producing One or More Optical Arrangements 有权用于使用光谱编码内窥镜技术获得信息的装置和用于产生一个或多个光学布置的方法公开(公告)号：US20120328241A1
公开(公告)日：2012-12-27
申请号：US13427463
申请日：2012-03-22
CPC分类号： G02B23/2453 , A61B1/00167 , A61B1/00188 , A61B1/002 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0084 , A61B5/0086 , B24B9/14 , G01J3/02 , G01J3/0205 , G01J3/0208 , G01J3/0218 , G01J3/0256 , G01J3/18 , G02B5/18 , G02B23/2469 , G02B23/26
摘要： Exemplary apparatus for obtaining information for a structure can be provided. For example, the exemplary apparatus can include at least one first optical fiber arrangement which is configured to transceive at least one first electro-magnetic radiation, and can include at least one fiber. The exemplary apparatus can also include at least one second focusing arrangement in optical communication with the optical fiber arrangement. The second arrangement can include a ball lens, and be configured to focus and provide there through the first electro-magnetic radiation to generate focused electro-magnetic radiation. Further, the exemplary apparatus can include at least at least one dispersive third arrangement which can receive a particular radiation (e.g., the first and/or focused electro-magnetic radiation(s), and forward a dispersed radiation thereof to at least one section of the structure. An end of the fiber(s) can be directly connected to the second focusing arrangement and/or the third arrangement(s).
摘要翻译： 可以提供用于获得结构信息的示例性装置。 例如，示例性装置可以包括被配置为收发至少一个第一电磁辐射的至少一个第一光纤布置，并且可以包括至少一个光纤。 示例性装置还可以包括与光纤布置光学通信的至少一个第二聚焦装置。 第二布置可以包括球透镜，并且被配置为通过第一电磁辐射聚焦并提供其中以产生聚焦的电磁辐射。 此外，示例性装置可以包括至少一个可接收特定辐射（例如，第一和/或聚焦的电磁辐射）并且将其分散的辐射转发到至少一个部分的分散第三布置 纤维的一端可以直接连接到第二聚焦装置和/或第三装置。
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23.发明授权Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements 有权用于使用光谱编码的内窥镜检查技术获得结构信息的装置和用于产生一个或多个光学装置的方法公开(公告)号：US08145018B2
公开(公告)日：2012-03-27
申请号：US11623852
申请日：2007-01-17
CPC分类号： G02B23/2453 , A61B1/00167 , A61B1/00188 , A61B1/002 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0084 , A61B5/0086 , B24B9/14 , G01J3/02 , G01J3/0205 , G01J3/0208 , G01J3/0218 , G01J3/0256 , G01J3/18 , G02B5/18 , G02B23/2469 , G02B23/26
摘要： Exemplary apparatus for obtaining information for a structure can be provided. For example, first optical fiber arrangement(s) can be provided which transceives at least one first electro-magnetic radiation, and can include at least one fiber. Second focusing arrangement(s) can be provided in optical communication with the optical fiber arrangement. The second arrangement can be configured to focus and provide there through the first electro-magnetic radiation. Third dispersive arrangement(s) can receive a particular radiation which is the first electro-magnetic radiation and/or the focused electro-magnetic radiation, and forward a dispersed radiation thereof to at least one section of the structure. At least one end of the fiber can be directly connected to the second focusing arrangement and/or the third dispersive arrangement.
摘要翻译： 可以提供用于获得结构信息的示例性装置。 例如，可以提供收发至少一个第一电磁辐射的第一光纤布置，并且可以包括至少一个光纤。 可以提供与光纤装置的光通信中的第二聚焦装置。 第二布置可以被配置成通过第一电磁辐射聚焦并提供到那里。 第三分散布置可以接收作为第一电磁辐射和/或聚焦电磁辐射的特定辐射，并将其分散的辐射转发到结构的至少一个部分。 光纤的至少一端可以直接连接到第二聚焦装置和/或第三色散装置。
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公开(公告)号：US20110149296A1
公开(公告)日：2011-06-23
申请号：US12910533
申请日：2010-10-22
IPC分类号： G01B9/02
CPC分类号： G01N33/4833 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/6852 , G01B9/02 , G01B9/02027 , G01B9/02049 , G01B9/02064 , G01B9/02087 , G01B9/02091 , G01B9/04 , G01N21/25 , G01N21/27 , G01N21/4795 , G01N21/6458 , G01N21/6486 , G01N23/046 , G01N2021/1765 , G01N2223/419 , G02B21/0028 , G02B23/2423 , G02B23/243 , G02B23/2461 , G02B23/2476
摘要： Exemplary method, apparatus and arrangement can be provided for obtaining information associated with a sample such as a portion of an anatomical structure. The information can be generated using first data, which can be based on a signal obtained from a location on the sample, and second data, where the second data can be obtained by combining a second signal received from the sample with a third reference signal. An image of a portion of the sample can also be generated based on the information. For example, the first data can be associated with spectral encoding microscopy data, and the second data can be associated with optical coherence tomography data.
摘要翻译： 可以提供示例性方法，装置和布置来获得与诸如解剖结构的一部分的样本相关联的信息。 可以使用可以基于从样本上的位置获得的信号的第一数据和第二数据来生成信息，其中可以通过将从样本接收的第二信号与第三参考信号组合来获得第二数据。 也可以基于该信息生成样本的一部分的图像。 例如，第一数据可以与光谱编码显微镜数据相关联，并且第二数据可以与光学相干断层扫描数据相关联。
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25.发明申请公开(公告)号：US20080262314A1
公开(公告)日：2008-10-23
申请号：US12104689
申请日：2008-04-17
IPC分类号： A61B1/00
CPC分类号： A61B1/227 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B5/4504
摘要： An apparatus and method according to an exemplary embodiment of to the present invention can provide imaging information associated with at least one portion of a sample. For example, at least two first different wavelengths of at least one first electromagnetic radiation within a first wavelength range may be provided on the portion of the sample so as to determine at least one first transverse location of the portion. At least two second different wavelengths of at least one second electromagnetic radiation may also be provided within a second wavelength range provided on the portion so as to determine at least one second transverse location of the portion. It is possible to obtain a relative phase between at least one third electromagnetic radiation electromagnetic radiation being returned from the sample and at least one fourth electromagnetic radiation returned from a reference to determine a motion of the portion or of particles within or on the portion, whereas the motion is effectuated by at least one of a sound wave. Further, the imaging information of the portion can be provided based on the first transverse location, the second transverse location and the motion.
摘要翻译： 根据本发明的示例性实施例的装置和方法可以提供与样本的至少一部分相关联的成像信息。 例如，可以在样品的该部分上提供在第一波长范围内的至少一个第一电磁辐射的至少两个第一不同波长，以便确定该部分的至少一个第一横向位置。 还可以在设置在该部分上的第二波长范围内提供至少两个第二不同波长的至少一个第二电磁辐射，以便确定该部分的至少一个第二横向位置。 可以获得从样品返回的至少一个第三电磁辐射电磁辐射与从参考物返回的至少一个第四电磁辐射之间的相对相位，以确定该部分或该部分内部或之上的颗粒的运动，而 运动由声波中的至少一个来实现。 此外，可以基于第一横向位置，第二横向位置和运动来提供该部分的成像信息。
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26.发明授权公开(公告)号：US09646377B2
公开(公告)日：2017-05-09
申请号：US14243508
申请日：2014-04-02
申请人： Guillermo J. Tearney , Milen Shishkov , Brett Eugene Bouma , Benjamin J. Vakoc , Norman S. Nishioka
发明人： Guillermo J. Tearney , Milen Shishkov , Brett Eugene Bouma , Benjamin J. Vakoc , Norman S. Nishioka
CPC分类号： A61B5/0084 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/6852 , A61B5/7271 , G06T7/0012 , G06T2207/10056 , G06T2207/10101
摘要： Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through. Another arrangement can be provided which is configured to measure a pressure within the at least one portion. The data may include a position and/or an orientation of the first arrangement with respect to the luminal or hollow sample.
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27.发明授权Apparatus, methods and storage medium for performing polarization-based quadrature demodulation in optical coherence tomography 有权用于在光学相干断层摄影中执行基于偏振的正交解调的装置，方法和存储介质公开(公告)号：US09441948B2
公开(公告)日：2016-09-13
申请号：US11502330
申请日：2006-08-09
CPC分类号： G01B9/02044 , A61B5/0059 , A61B5/0066 , G01B9/02004 , G01B9/02072 , G01B9/02081 , G01B9/02091 , G01B2290/45 , G01B2290/70 , G01J3/45 , G01J2009/0265 , G01N21/21 , G01N21/274 , G01N21/4795
摘要： Apparatus, method and storage medium which can provide at least one first electro-magnetic radiation to a sample and at least one second electromagnetic radiation to a reference, such that the first and/or second electromagnetic radiations have a spectrum which changes over time. In addition, a first polarization component of at least one third radiation associated with the first radiation can be combined with a second polarization component of at least one fourth radiation associated with the second radiation with one another. The first and second polarizations may be specifically controlled to be at least approximately orthogonal to one another.
摘要翻译： 可以向样品提供至少一个第一电磁辐射和至少一个第二电磁辐射至参考物的装置，方法和存储介质，使得第一和/或第二电磁辐射具有随时间变化的光谱。 此外，与第一辐射相关联的至少一个第三辐射的第一偏振分量可以与与第二辐射相关联的至少一个第四辐射的第二偏振分量彼此组合。 可以将第一和第二偏振特别地控制为至少大致彼此正交。
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28.发明授权公开(公告)号：US09186066B2
公开(公告)日：2015-11-17
申请号：US11670027
申请日：2007-02-01
CPC分类号： A61B5/0084 , A61B5/0066 , A61B5/6852 , A61B18/24 , A61B2017/00057 , A61B2017/22051 , A61B2018/207 , A61B2090/306 , A61B2090/3614
摘要： An apparatus for applying a plurality of electro-magnetic radiations to a sample is provided. In one exemplary embodiment, the apparatus can include an arrangement which has a specific portion with a plurality of channels. One of channels can facilitate a first radiation of the radiations to be forwarded to the sample that is within an anatomical structure, and another one of the channels can facilitate a second radiation of the radiations to be forwarded to the sample. The first radiation may have a first wavelength band, and the second radiation may have a second wavelength band. The first wavelength band may be substantially different from the second wavelength band. According to another exemplary embodiment, the first radiation can be adapted to be delivered to a first area of the sample, and the second radiation may be capable of being delivered to a second area of the sample. The first area may be substantially enclosed by the second area. According to yet another exemplary embodiment of the present invention, each of the channels can facilitate at least one particular radiation of the radiations to be forwarded to the sample that is within an anatomical structure of the sample, the radiations being delivered to different areas of the sample. Centers of every one of the areas may be provided substantially along a line.
摘要翻译： 提供了一种向样品施加多个电磁辐射的装置。 在一个示例性实施例中，装置可以包括具有多个通道的特定部分的装置。 通道中的一个可以促进要转发到解剖结构内的样品的辐射的第一辐射，并且另一个通道可以促进辐射的第二次辐射以被转发到样品。 第一辐射可以具有第一波长带，并且第二辐射可以具有第二波长带。 第一波长带可能与第二波长带显着不同。 根据另一示例性实施例，第一辐射可以适于被传送到样品的第一区域，并且第二辐射可以能够被传送到样品的第二区域。 第一区域可以基本上被第二区域包围。 根据本发明的另一个示例性实施例，每个通道可以促进辐射的至少一个特定辐射被转发到样品的解剖结构内的样品，辐射被递送到样品的解剖结构中 样品。 可以基本沿着一条线提供每个区域的中心。
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29.发明申请METHODS AND SYSTEMS FOR OPTICAL IMAGING OR EPITHELIAL LUMINAL ORGANS BY BEAM SCANNING THEREOF 有权通过光束扫描对光学成像或上传光学仪器的方法和系统公开(公告)号：US20140301620A1
公开(公告)日：2014-10-09
申请号：US14243508
申请日：2014-04-02
申请人： Guillermo J. Tearney , Milen Shishkov , Brett Eugene Bouma , Benjamin J. Vakoc , Norman S. Nishioka
发明人： Guillermo J. Tearney , Milen Shishkov , Brett Eugene Bouma , Benjamin J. Vakoc , Norman S. Nishioka
IPC分类号： G06T7/00
CPC分类号： A61B5/0084 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/6852 , A61B5/7271 , G06T7/0012 , G06T2207/10056 , G06T2207/10101
摘要： Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through. Another arrangement can be provided which is configured to measure a pressure within the at least one portion. The data may include a position and/or an orientation of the first arrangement with respect to the luminal or hollow sample.
摘要翻译： 提供了布置，装置，系统和系统以获得至少一个管腔或中空样品中的至少一个部分的数据。 该装置，系统或装置可以（可通过患者的嘴部或鼻子中的至少一个插入），例如，第一光学装置可以被配置为收发至少一个电磁（例如，可见） 第二布置可以至少部分地包围第一布置。此外，第三布置可被配置为被致动以将第一布置定位在管腔或中空样品内的预定位置处，第一布置可以是 被配置为补偿由第二布置和/或第三布置引起的至少一个像差（例如，散光），第二布置可以包括使引导布置能够插入到其中的至少一个部分，可以提供另一种布置 其被配置为测量所述至少一个部分内的压力，所述数据可以包括所述第一装置的位置和/或取向与r 对于管腔或空心样品。
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30.发明授权Apparatus for controlling at least one of at least two sections of at least one fiber 有权用于控制至少一个光纤的至少两个部分中的至少一个的装置公开(公告)号：US07418169B2
公开(公告)日：2008-08-26
申请号：US11670069
申请日：2007-02-01
CPC分类号： A61B18/24 , A61B1/00082 , A61B1/00096 , A61B1/00172 , A61B1/00183 , A61B5/0066 , A61B5/0084 , A61B5/6852 , A61B2017/00057 , A61B2017/22051 , A61B2018/2211 , A61B2018/2272 , G02B23/2423
摘要： An apparatus for controlling at least one of at least two sections of at least one fiber can be provided. The apparatus can include an arrangement which may be provided between the first and second sections of a particular continuous fiber of the fibers. A particular one of the first and second sections may be provided in a particular orientation that is perpendicular to an extension of the particular fiber. The arrangement is capable of controlling the particular fiber such that the particular one of the sections is capable of being rotated for at least 360° with respect to the particular orientation. The arrangement can include a further arrangement that is capable of at least partially wrapping the particular fiber around the second arrangement, and controlling the particular fiber such that the particular one of the sections is capable of being rotated with respect to the particular orientation during a transmission of the electro-magnetic radiation.
摘要翻译： 可以提供一种用于控制至少一个光纤的至少两个部分中的至少一个的装置。 该装置可以包括可以设置在纤维的特定连续纤维的第一和第二部分之间的装置。 第一和第二部分中的特定一个可以以垂直于特定纤维的延伸部的特定方向设置。 该装置能够控制特定光纤，使得特定的一个部分能够相对于特定取向旋转至少360°。 该布置可以包括能够至少部分地围绕第二布置包围特定纤维并且控制特定光纤的另外的布置，使得特定的一个部分能够在传输期间相对于特定取向旋转 的电磁辐射。
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