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公开(公告)号：US10238107B2
公开(公告)日：2019-03-26
申请号：US15329653
申请日：2015-04-01
Applicant: KIMBERLY-CLARK WORLDWIDE, INC.
Inventor： Vinod Chaudhary , Kathleen C. Engelbrecht , David W. Koenig , Divesh Bhatt , Amy L. Vanden Heuvel , Scott W. Wenzel , Stacy A. Mundschau
IPC: A01N31/02 , A01N25/02 , A01N25/08 , A01N37/44 , A01N41/08 , A01N43/36 , A01N45/00 , A01N47/20 , A01N55/00 , A01N63/02 , A01N65/00 , C08L71/02 , A61K8/02 , A61Q17/00 , A61K8/81 , A61K8/86 , A61K8/891 , A61K8/893 , A61K8/895 , A61K8/898 , A61K8/90 , A61K8/92 , A61K8/97 , A01N65/12 , A01N65/18
Abstract: Compositions for inhibiting the attachment of microbes to a biotic or abiotic surface are disclosed. The compositions include a carrier and an effective amount of an anti-adherent agent. The anti-adherent agents include Dimethicone Propyl PG-Betaine, PEG-150/Decyl Alcohol/SMDI Copolymer, Ammonium Acryloyl Dimethyltaurate/Carboxyethyl, Acrylate Crosspolymer, PEG-20 Soy Sterol, PEG/PPG-25/25 Dimethicone, PEG-12 Dimethicone, Dimethicone, Cyclopentasiloxane (and) PEG-12 Dimethicone Crosspolymer, PPG-12-PEG-50 Lanolin, Glycerin (and) Glycine Max (Soybean) Seed Extract, VP/Dimethiconylacrylate/Polycarbamyl/Polyglycol Ester, PEG-10 Sunflower Glycerides, PEG-8 Amodimethicone, PEG/PPG 20/23 Dimethicone Isobutylene/Ethylmaleimide/Hydroxyethylmaleimide Copolymer, Methacryloyl Ethyl Betaine/Acrylates Copolymer, Poloxamer 407, Ethylene Oxide/Propylene Oxide Block Copolymer, PEG-200 Hydrogenated Castor Oil/IPDI Copolymer, PEG-15 Soyamine/IPDI Copolymer Dimer Dilinoleate, Dimethicone PEG-7 Isostearate, PEG-12 Dimethicone, PEG-17 Dimethicone, Polyoxyethylene Polyoxypropylene block copolymer, Polyalkyleneoxide modified silicone copolymer, Disteareth-75 IPDI, and combinations thereof. Various delivery vehicles, including wipes, may be used to deliver the composition to surfaces.
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公开(公告)号：US20190015308A1
公开(公告)日：2019-01-17
申请号：US16011248
申请日：2018-06-18
Applicant: KIMBERLY-CLARK WORLDWIDE, INC.
Inventor： Vinod Chaudhary , Scott W. Wenzel , Kathleen C. Engelbrecht , David W. Koenig , Amy L. Vanden Heuvel , Divesh Bhatt , Paige N. Hollmaier (Anunson) , Stacy A. Mundschau
Abstract: The present disclosure is directed to alcohol-based anti-adherent compositions that do not adhere to or attract Gram-negative and Gram-positive bacteria once it is applied to a surface and dried. The composition may include as anti-adherent agents, hydrophilic film-formers such as cellulosics, gums, acrylates, nonionic polymers, and anionic polymers. Examples of anti-adherent agents include Hydroxypropyl methylcellulose, Cellulose gum, Acacia Senegal Gum; Polyacrylate Crosspolymer-11, VP/Dimethylaminoethylmethacrylate/Polycarbamyl Polyglycol Ester; Acrylates/Vinyl Neodecanoate Crosspolymer, hydroxypropyl methylcellulose, Hydroxypropylcellulose, Methylcellulose, Propylene Glycol Alginate, Polyacrylate Crosspolymer-6, VP/Polycarbamyl Polyglycol Ester, Acrylates/Steareth-20 Methacrylate Copolymer; Acrylates Copolymer, and any combination thereof. The anti-adherent may be applied to surfaces using a vehicle such as a wipe.
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公开(公告)号：US20170322212A1
公开(公告)日：2017-11-09
申请号：US15526939
申请日：2014-11-27
Applicant: KIMBERLY-CLARK WORLDWIDE, INC.
Inventor： Bao Trong Do , Jonathan Hofmekler , Cesar A. Morales , David W. Koenig , Yang Huang , Aimin He
IPC: G01N33/569 , G01N33/558
CPC classification number: G01N33/56983 , G01N33/558 , G01N2333/08 , G01N2469/10
Abstract: Lateral-flow assay and time-resolved fluorescence technologies provide a sensitive tool for detecting norovirus particles in a sample. A flow-through assay device employs norovirus and norovirus G2 antibodies. The lateral-flow assay includes a conjugate pad having conjugated probes. The conjugated probes are particles modified with a binding member that is configured to bind with a norovirus. The particles also have a fluorescent label. A general method of detecting the virus includes (i) preparing a sample with contaminants, (ii) processing the sample and depositing it onto the assay device, and (iii) measuring the fluorescence signal.
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公开(公告)号：US20170224596A1
公开(公告)日：2017-08-10
申请号：US15500671
申请日：2015-04-01
Applicant: KIMBERLY-CLARK WORLDWIDE, INC.
Inventor： Vinod Chaudhary , Scott W. Wenzel , Kathleen C. Engelbrecht , David W. Koenig , Amy L. Vanden Heuvel , Divesh Bhatt , Paige N. Anunson , Stacy A. Mundschau
CPC classification number: A61K8/34 , A61K8/0208 , A61K8/73 , A61K8/731 , A61K8/8152 , A61Q17/005 , C09D5/14 , C09D101/28 , C09D101/284
Abstract: The present disclosure is directed to alcohol-based anti-adherent compositions that do not adhere to or attract Gram-negative and Gram-positive bacteria once it is applied to a surface and dried. The composition may include as anti-adherent agents, hydrophilic film-formers such as cellulosics, gums, acrylates, nonionic polymers, and anionic polymers. Examples of anti-adherent agents include Hydroxypropyl methylcellulose, Cellulose gum, Acacia Senegal Gum; Polyacrylate Crosspolymer-11, VP/Dimethyl-aminoethylmethacrylate/Polycarbamyl Polyglycol Ester; Acrylates/Vinyl Neodecanoate Crosspolymer, hydroxypropyl methylcellulose, Hydroxypropylcellulose, Methylcellulose, Propylene Glycol Alginate, Polyacrylate Crosspolymer-6, VP/Polycarbamyl Polyglycol Ester, Acrylates/Steareth-20 Methacrylate Copolymer; Acrylates Copolymer, and any combination thereof. The anti-adherent may be applied to surfaces using a vehicle such as a wipe.
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公开(公告)号：US20170172153A1
公开(公告)日：2017-06-22
申请号：US15129668
申请日：2015-03-18
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor： David W. Koenig , Douglas R. Hoffman , Cindy Korir-Morrison , Amy L. Vanden Heuvel
CPC classification number: A01N63/00 , A01N25/10 , A01N25/34 , C09D5/14 , C09D7/65 , C12N7/00 , C12N2750/00031 , A01N63/02
Abstract: A composition may be applied to animate and inanimate surfaces to render such surfaces antimicrobial for as long as the composition remains on the surface. The composition contains at least one pathogen-associated virus that is self-regenerating so that a user need not take steps to regenerate the material. The virus is or viruses are contained within a polymer matrix. The polymer matrix has the ability to maintain a desired moisture content to support the regeneration of the virus(es). Various methods of using the composition include the coating of animate and inantimate surfaces to prevent bacterial, viral, and fungal infections.
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Patent Agency Ranking
公开(公告)号：US20150238642A1
公开(公告)日：2015-08-27
申请号：US14191617
申请日：2014-02-27
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor： Jose K. Abraham , Paige Anunson , Kathleen C. Engelbrecht , David W. Koenig
IPC: A61L2/03
CPC classification number: A61L2/03 , A61L2/04 , A61L2202/26
Abstract: A system for removing microorganisms from a surface is described. The system includes a conducting member, a voltage source, and an electrostatic field controller. The conducing member includes a nonwoven material incorporating conductive fibers. The controller is electrically connected to the conducting member and is configured to apply a DC voltage of about 15 volts or less to the conducting member via the voltage source. The surface to be contacted can include any surface present in households, food industry facilities, medical facilities, etc. Such surfaces can include tables, countertops, walls, cabinets, doors, door handles, door knobs, etc. The system can also be used to treat devices used in the aforementioned environments, such as food preparation equipment, medical devices, household appliances, etc. The system can reduce the amount of microorganisms on the surface by at least about 1 log (90%) without the use of chemicals, high voltages, or long exposure times.
Abstract translation: 描述了从表面除去微生物的系统。 该系统包括导电构件，电压源和静电场控制器。 引导构件包括结合导电纤维的非织造材料。 控制器电连接到导电构件，并且被配置为经由电压源向导电构件施加约15伏或更小的直流电压。 要接触的表面可以包括家庭中存在的任何表面，食品工业设施，医疗设施等。这些表面可以包括桌子，台面，墙壁，橱柜，门，门把手，门把手等。还可以使用该系统 用于治疗上述环境中使用的装置，例如食物制备设备，医疗器械，家用电器等。该系统可以在不使用化学物质的情况下将表面上的微生物量减少至少约1log（90％）， 高电压或长曝光时间。
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公开(公告)号：US20230277704A1
公开(公告)日：2023-09-07
申请号：US18309329
申请日：2023-04-28
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor： Douglas R. Hoffman , Amy L. Vanden Heuvel , Jeremy D. Paulsen , Paige N. Anunson , Lisa M. Kroll , Corey T. Cunningham , David W. Koenig
IPC: A61L2/18 , A61K31/194 , A61K31/205 , A61K31/661 , A61K45/06 , A61P31/12
CPC classification number: A61L2/18 , A61K31/194 , A61K31/205 , A61K31/661 , A61K45/06 , A61P31/12 , Y02A50/30
Abstract: A disinfectant composition that contains a unique combination of a primary antiviral agent and a secondary antiviral agent is provided. More particularly, the primary antiviral agent includes a polyprotic acid having a low first acid dissociation constant and the secondary antiviral agent is selected from the group consisting of an anionic N-acyl compound, metal halide salt, amine compound, amine compound, aliphatic amine oxide, alkyl glycoside, alcohol ethoxylate, and combinations thereof. By selectively controlling the particular nature of each antiviral agent and their relative concentration, the present inventors have discovered that a synergistic affect can be achieved in which the disinfectant composition is capable of exhibiting an antiviral efficacy against non-enveloped viruses.
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28.发明授权公开(公告)号：US11311429B2
公开(公告)日：2022-04-26
申请号：US17426910
申请日：2019-01-31
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor： David W. Koenig , Jonathan Hofmekler , Lindsay A. Peed , Jeffery R. Seidling , Scott W. Wenzel
IPC: A61F13/15 , A61F13/84 , A61F13/511 , A61L15/28 , A61L15/46 , A61F13/514
Abstract: Methods and products for maintaining a target pH range of an environment including at least one organism are provided. A method can include releasing a carbon source to the environment. A method can further include allowing the carbon source to be metabolized by the at least one organism and lower a pH of the environment. The method can also include releasing a nitrogen source to the environment. The method can additionally include allowing the nitrogen source to be metabolized by the at least one organism and increase the pH of the environment. The releasing of the carbon source to the environment and the releasing of the nitrogen source to the environment can be selectively timed to control the pH of the environment to the target pH range of the environment.
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29.发明申请公开(公告)号：US20220096287A1
公开(公告)日：2022-03-31
申请号：US17426910
申请日：2019-01-31
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor： David W. Koenig , Jonathan Hofmekler , Lindsay A. Peed , Jeffery R. Seidling , Scott W. Wenzel
IPC: A61F13/84 , A61F13/15 , A61F13/511 , A61F13/514 , A61L15/28 , A61L15/46
Abstract: Methods and products for maintaining a target pH range of an environment including at least one organism are provided. A method can include releasing a carbon source to the environment. A method can further include allowing the carbon source to be metabolized by the at least one organism and lower a pH of the environment. The method can also include releasing a nitrogen source to the environment. The method can additionally include allowing the nitrogen source to be metabolized by the at least one organism and increase the pH of the environment. The releasing of the carbon source to the environment and the releasing of the nitrogen source to the environment can be selectively timed to control the pH of the environment to the target pH range of the environment.
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30.发明申请公开(公告)号：US20220062356A1
公开(公告)日：2022-03-03
申请号：US17415020
申请日：2019-12-20
Applicant: Gregor Reid , Jeremy P. Burton , Behnam Abbasian , Kimberly-Clark Worldwide, Inc.
Inventor： Kathleen C. Engelbrecht , David W. Koenig , Elizabeth M. Doney , Gregor Reid , Jeremy Burton , Behnam Abbasian
IPC: A61K35/747
Abstract: Methods and compositions for preventing or treating incontinence, overactive bladder, or menstrual cramping in a subject are described. A method can include providing a composition. The composition can include a modification agent. The modification agent can include a strain of Lactobacillus or a ferment or a metabolite thereof. The modification agent can provide neuromodulation activity by up-regulating at least one of maoA enzymes, maoB enzymes, and grin-1 genes. The method can also include administering the composition to the subject to prevent or treat incontinence, overactive bladder, or menstrual cramping. In some aspects, the modification agent can decrease a level of extracellular ATP in a target environment.
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