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    Blood processing systems and methods for collecting mono nuclear cells
    22.
    发明授权
    Blood processing systems and methods for collecting mono nuclear cells 失效
    用于收集单核细胞的血液处理系统和方法

    公开(公告)号：US5573678A

    公开(公告)日：1996-11-12

    申请号：US472750

    申请日：1995-06-07

    申请人： Richard I. Brown ,  Kyungyoon Min

    发明人： Richard I. Brown ,  Kyungyoon Min

    IPC分类号： A61K35/14 ,  A61M1/02 ,  A61M1/30 ,  A61M1/36 ,  B01D17/02 ,  B01D21/24 ,  B01D21/26 ,  B04B5/04 ,  B04B7/08 ,  B04B13/00

    CPC分类号： A61M1/0209 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3603 ,  A61M1/3624 ,  A61M1/3693 ,  A61M1/3696 ,  B01D17/0217 ,  B01D21/003 ,  B01D21/0087 ,  B01D21/2405 ,  B01D21/245 ,  B01D21/262 ,  B01D21/32 ,  B01D21/34 ,  B04B13/00 ,  B04B5/0442 ,  B04B7/08 ,  A61M1/025 ,  A61M1/30 ,  A61M2202/0427 ,  A61M2205/331 ,  A61M2205/3344 ,  A61M2205/3351 ,  A61M2205/3355 ,  A61M2205/3393 ,  B01D2221/10 ,  B04B2005/045

    摘要： Systems and methods for separating mono nuclear cells from whole blood rotate a separation chamber about a rotational axis. The systems and methods introduce whole blood into a first region of the chamber during its rotation to separate the whole blood into a plasma constituent, red blood cells, and an interface between the red blood cells and the plasma constituent. The interface carries mono nuclear cells. While conveying whole blood into the first region, the systems and methods collect the plasma constituent in the first region, while also collecting the red blood cells in a second region of the chamber spaced from the inlet region. The systems and methods create, while conveying whole blood into the inlet region, a back flow of plasma constituent along the interface from the second region toward the inlet region. This back flow of plasma maintains a high-relative hematocrit in the second region and a low-relative hematocrit in the inlet region. The mono nuclear cells are confined between the low-relative hematocrit inlet region and the high-relative second region. The system and method then convey red blood cells into the second region in a back flow direction toward the inlet region. While conveying red blood cells into the second region, the systems and methods collect the mono nuclear cells in the first region.

    摘要翻译： 用于从全血分离单核细胞的系统和方法围绕旋转轴旋转分离室。 该系统和方法在其旋转期间将全血引入腔室的第一区域，以将全血分离成等离子体成分，红细胞以及红细胞和血浆成分之间的界面。 接口携带单核细胞。 当将全血输送到第一区域时，系统和方法收集第一区域中的等离子体成分，同时还在与入口区间隔开的第二区域中收集红细胞。 系统和方法在将全血输送到入口区域时产生沿着从第二区域朝向入口区域的界面的等离子体成分的回流。 血浆的这种反向流维持第二区域中的高相对血细胞比容和入口区域中的低相对血细胞比容。 单核细胞被限制在低相对红细胞压积入口区域和高相对第二区域之间。 然后，该系统和方法将红血细胞沿回流方向传送到第二区域中。 在将红细胞输送到第二区域时，系统和方法在第一区域收集单核细胞。

    Methods for determining flow rates of biological fluids
    23.
    发明授权
    Methods for determining flow rates of biological fluids 有权
    确定生物体液流速的方法

    公开(公告)号：US07087177B2

    公开(公告)日：2006-08-08

    申请号：US10826086

    申请日：2004-04-16

    申请人： Kyungyoon Min ,  Richard I. Brown

    发明人： Kyungyoon Min ,  Richard I. Brown

    IPC分类号： B01D21/26 ,  G01F1/00 ,  B01D21/32 ,  B04B11/00

    CPC分类号： A61M1/3693 ,  A61M1/3696

    摘要： A separation method comprises introducing a first fluid comprising first and second components having different density into a centrifugal field and allowing an interface to form between at least portions of such components at a first location. The method also comprises moving the interface from the first location to a second location and further comprises introducing the first fluid and removing one of the first and second components at known controlled flow rates so as to move the interface from the second location in a direction toward the first location and to return the interface to the second location. The flow rate of the first or second component may be determined based, at least in part, on the time interval between the interface moving from and returning to the second location. The flow rate may also be based on the weight of the one component removed during the time interval.

    摘要翻译： 分离方法包括将包含具有不同密度的第一和第二组分的第一流体引入到离心场中，并允许在第一位置处在这些组分的至少部分之间形成界面。 该方法还包括将界面从第一位置移动到第二位置，并且进一步包括引入第一流体并以已知的受控流速移除第一和第二组分中的一个，以便使接口从第二位置朝向 第一个位置并将界面返回到第二个位置。 至少部分地基于从第二位置移动到返回到第二位置的界面之间的时间间隔来确定第一或第二部件的流量​​。 流量也可以基于在时间间隔期间去除的一个部件的重量。

    Method for the concentration of fluid-borne pathogens
    25.
    发明授权
    Method for the concentration of fluid-borne pathogens 有权
    流体传播病原体浓度的方法

    公开(公告)号：US06500107B2

    公开(公告)日：2002-12-31

    申请号：US09874731

    申请日：2001-06-05

    申请人： Richard I. Brown ,  Kyungyoon Min

    发明人： Richard I. Brown ,  Kyungyoon Min

    IPC分类号： B01D2126

    CPC分类号： B04B5/0428 ,  A61M1/362 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/20 ,  B04B5/0442 ,  B04B2005/045 ,  C12M33/10

    摘要： Methods and apparatus for concentrating and recovering pathogens from a fluid other than blood are disclosed. The method includes concentrating the pathogens contained in the fluid by continuously feeding the fluid through one or more flexible chamber(s) and subjecting the chamber(s) to centrifugal forces. The concentrated pathogens may be re-suspended by shaking the chamber(s).

    摘要翻译： 公开了从血液以外的流体浓缩和回收病原体的方法和装置。 该方法包括通过将流体连续地供给到一个或多个柔性室中并对该室进行离心力来浓缩包含在流体中的病原体。 浓缩的病原体可以通过摇动室来重新悬浮。

    Systems and methods for collecting diluted mononuclear cells
    26.
    发明授权
    Systems and methods for collecting diluted mononuclear cells 失效
    用于收集稀释的单核细胞的系统和方法

    公开(公告)号：US6027657A

    公开(公告)日：2000-02-22

    申请号：US886732

    申请日：1997-07-01

    申请人： Kyungyoon Min ,  Richard I Brown ,  Robert J Cantu

    发明人： Kyungyoon Min ,  Richard I Brown ,  Robert J Cantu

    IPC分类号： A61K35/14 ,  A61M1/36 ,  A61M1/38 ,  B01D21/26 ,  B04B5/04

    CPC分类号： B01D21/302 ,  A61M1/3693 ,  A61M1/3696 ,  A61M1/38 ,  B01D21/262 ,  B04B5/0442 ,  B01D2221/10 ,  B04B2005/045

    摘要： Systems and methods rotate a chamber, in which whole blood is centrifugally separated into packed red blood cells, a plasma constituent, and an interface between the packed red blood cells and the plasma constituent. The interface carries platelets and mononuclear cells. The systems and methods include an interface control unit. The interface control unit is operative in a first state to enable removal of platelet-poor plasma in a first container for use as a diluting liquid. In a second state, the interface control unit retains mononuclear cells in the chamber, while removing platelet-rich plasma from the chamber, bypassing the platelet-poor collection container, thereby maintaining its platelet-poor character. In a third state, the interface control unit enables the removal of mononuclear cells from the chamber in a path that leads to a second container, where the mononuclear cells are collected. The systems and methods direct platelet-poor plasma from the first container to the second container to dilute the removed mononuclear cells in the second container.

    摘要翻译： 系统和方法旋转室，其中全血离心分离成包装的红细胞，血浆成分以及填充的红细胞和血浆成分之间的界面。 界面携带血小板和单核细胞。 系统和方法包括接口控制单元。 界面控制单元在第一状态下操作以使得能够在用作稀释液体的第一容器中移除贫血小血浆。 在第二状态下，界面控制单元在腔室中保留单核细胞，同时从腔室中除去富含血小板的血浆，绕过血小板收集容器，从而维持其血小板减少的特征。 在第三状态下，界面控制单元能够在通向收集单核细胞的第二容器的路径中从腔室去除单核细胞。 系统和方法将血小板从第一容器直接引导到第二容器，以稀释第二容器中去除的单核细胞。

    Display device, display method, and multimedia transmission method
    29.
    发明授权
    Display device, display method, and multimedia transmission method 有权
    显示设备，显示方式和多媒体传输方式

    公开(公告)号：US09131268B2

    公开(公告)日：2015-09-08

    申请号：US13643734

    申请日：2011-09-28

    申请人： Kyungyoon Min

    发明人： Kyungyoon Min

    IPC分类号： G06F3/038 ,  G09G5/00 ,  H04N21/4363 ,  H04N5/765 ,  G06F3/14

    CPC分类号： H04N21/43635 ,  G06F3/1446 ,  G09G5/006 ,  G09G2358/00 ,  G09G2370/04 ,  G09G2370/10 ,  G09G2370/12 ,  H04N5/765

    摘要： Provided are a display device configuring a multi-display and a display method. The multi-media display receives a DisplayPort signal from outside, converts the received signal into a set of LVTTL signals, converts a portion of the LVTTL signals into a high-quality image signal capable of using HDMI to display multimedia on a corresponding display device, and converts another portion of the LVTTL signals into a DisplayPort signal to transmit the DisplayPort signal to another display device. Accordingly, an infinite multi-display can display high quality multimedia.

    摘要翻译： 提供了构成多显示器和显示方法的显示装置。 多媒体显示器从外部接收DisplayPort信号，将接收到的信号转换为一组LVTTL信号，将一部分LVTTL信号转换为能够使用HDMI在相应显示装置上显示多媒体的高质量图像信号， 并将LVTTL信号的另一部分转换成DisplayPort信号，以将DisplayPort信号传输到另一显示设备。 因此，无限多显示器可以显示高质量的多媒体。

    DISPLAY DEVICE, DISPLAY METHOD, AND MULTIMEDIA TRANSMISSION 10 METHOD
    30.
    发明申请
    DISPLAY DEVICE, DISPLAY METHOD, AND MULTIMEDIA TRANSMISSION 10 METHOD 有权
    显示设备，显示方法和多媒体传输10方法

    公开(公告)号：US20130038508A1

    公开(公告)日：2013-02-14

    申请号：US13643734

    申请日：2011-09-28

    申请人： Kyungyoon Min

    发明人： Kyungyoon Min

    IPC分类号： G09G5/00 ,  G06F3/038

    CPC分类号： H04N21/43635 ,  G06F3/1446 ,  G09G5/006 ,  G09G2358/00 ,  G09G2370/04 ,  G09G2370/10 ,  G09G2370/12 ,  H04N5/765

    摘要： Provided are a display device configuring a multi-display and a display method. The multi-media display receives a DisplayPort signal from outside, converts the received signal into a set of LVTTL signals, converts a portion of the LVTTL signals into a high-quality image signal capable of using HDMI to display multimedia on a corresponding display device, and converts another portion of the LVTTL signals into a DisplayPort signal to transmit the DisplayPort signal to another display device. Accordingly, an infinite multi-display can display high quality multimedia.

    摘要翻译： 提供了构成多显示器和显示方法的显示装置。 多媒体显示器从外部接收DisplayPort信号，将接收到的信号转换为一组LVTTL信号，将一部分LVTTL信号转换为能够使用HDMI在相应显示装置上显示多媒体的高质量图像信号， 并将LVTTL信号的另一部分转换成DisplayPort信号，以将DisplayPort信号传输到另一显示设备。 因此，无限多显示器可以显示高质量的多媒体。