公开(公告)号：US07482072B2

公开(公告)日：2009-01-27

申请号：US10615666

申请日：2003-07-09

申请人： Juliana H. J. Brooks ,  Bentley J. Blum ,  Mark G. Mortenson

发明人： Juliana H. J. Brooks ,  Bentley J. Blum ,  Mark G. Mortenson

IPC分类号： H01M2/00 ,  H01M8/00 ,  H01M8/18 ,  H01M4/00 ,  C07C1/00

CPC分类号： H01M8/0606 ,  B01J19/121 ,  B01J19/122 ,  B01J19/127 ,  B01J23/42 ,  B01J37/344 ,  C01B3/0026 ,  C01B3/0031 ,  C01B5/00 ,  C01B13/0214 ,  C01D3/04 ,  C01D3/10 ,  H01M4/90 ,  H01M8/00 ,  H01M8/16 ,  Y02E60/327 ,  Y02E60/527 ,  Y02P20/135

摘要： This invention relates to novel methods for affecting, controlling and/or directing various reactions and/or reaction pathways or systems by exposing one or more components in a fuel cell reaction system to at least one spectral energy pattern. In a first aspect of the invention, at least one spectral energy pattern can be applied to a fuel cell reaction system. In a second aspect of the invention, at least one spectral energy conditioning pattern can be applied to a conditioning reaction system. The spectral energy conditioning pattern can, for example, be applied at a separate location from the reaction vessel (e.g., in a conditioning reaction vessel) or can be applied in (or to) the reaction vessel, but prior to other reaction system participants being introduced into the reaction vessel.

摘要翻译： 本发明涉及通过将燃料电池反应系统中的一种或多种组分暴露于至少一种光谱能量图案来影响，控制和/或指导各种反应和/或反应途径或系统的新方法。 在本发明的第一方面中，至少一种光谱能量图案可以应用于燃料电池反应系统。 在本发明的第二方面，至少一种光谱能量调节模式可以应用于调理反应系统。 例如，光谱能量调节图案可以在与反应容器（例如在调节反应容器中）分开的位置处施加，或者可以应用于反应容器中（或到其中），但在其它反应系统参与者之前 引入反应容器。

公开(公告)号：US20080165634A1

公开(公告)日：2008-07-10

申请号：US12025413

申请日：2008-02-04

申请人： Juliana H. J. Brooks ,  Mark G. Mortenson

发明人： Juliana H. J. Brooks ,  Mark G. Mortenson

IPC分类号： G11B5/09

CPC分类号： G11B5/00 ,  B82Y10/00 ,  B82Y25/00 ,  G11B5/012 ,  G11B5/02 ,  G11B5/09 ,  G11B7/00 ,  G11B7/00455 ,  G11B7/0052 ,  G11B7/0065 ,  G11B7/127 ,  G11B7/128 ,  G11B7/1381 ,  G11B7/24088 ,  G11B9/00 ,  G11B2005/0002 ,  G11B2005/3996 ,  G11C13/06

摘要： The present invention relates generally to the storage of information on magnetic and/or optical storage media by using one or more novel approaches alone or in combination. These novel approaches are capable of using at least one code which may comprise more than two values (i.e., more than a “0” and a “1”). A first series of approaches for the storage of information applies generally to optical storage/retrieval systems (e.g., CD's, DVD's, etc.); while a second series of approaches applies generally to electric and/or magnetic storage/retrieval systems (e.g., magnetic, magneto-optic, etc.). Each series of approaches is capable of storing information in one or more codes, wherein such approaches permit, if desired, the use of at least one higher order code which is different from the traditional binary code of “0's” and “1's” currently utilized for the storage of digital information. Said at least one higher order code may comprise three or more optical and/or magnetic values or bits that are used to represent, for example, ASCII or Unicode characters that are currently represented predominantly by the traditional binary code. This higher order code may also be an analog or analog-like code.

摘要翻译： 本发明一般涉及通过单独或组合使用一种或多种新颖方法来存储关于磁性和/或光学存储介质的信息。 这些新颖的方法能够使用至少一个可以包括多于两个值（即大于“0”和“1”）的代码。 用于存储信息的第一系列方法通常适用于光学存储/检索系统（例如CD，DVD等）; 而第二系列方法通常适用于电和/或磁存储/检索系统（例如，磁性，磁光学等）。 每一系列方法能够将信息存储在一个或多个代码中，其中如果需要，这样的方法允许使用与当前使用的“0”和“1”的传统二进制代码不同的至少一个更高阶代码 用于存储数字信息。 所述至少一个较高阶代码可以包括用于表示例如主要由传统二进制代码表示的ASCII或Unicode字符的三个或更多个光学和/或磁性值或位。 该较高阶代码也可以是模拟或类似模拟的代码。

公开(公告)号：US5501263A

公开(公告)日：1996-03-26

申请号：US976989

申请日：1993-01-08

申请人： Ratnesh K. Dwivedi ,  Kurt J. Becker ,  Danny R. White ,  Steven D. Keck ,  Mark G. Mortenson

发明人： Ratnesh K. Dwivedi ,  Kurt J. Becker ,  Danny R. White ,  Steven D. Keck ,  Mark G. Mortenson

IPC分类号： C04B35/622 ,  C04B35/65 ,  C22C1/10 ,  C22C47/00 ,  C22C47/08 ,  C22C47/12 ,  B22D19/14

CPC分类号： C22C1/1036 ,  C04B35/652 ,  B22F2003/1014 ,  C22C2001/1063

摘要： The present invention relates to a novel process for making a macrocomposite body. Specifically, a metal matrix composite body is first formed and thereafter, a ceramic body or a ceramic matrix composite body is caused to form from at least one surface of the already formed metal matrix composite body. The ceramic or ceramic composite body can be formed by, for example, changing from spontaneous infiltration conditions which permit a molten matrix metal to infiltrate a filler material or preform to conditions which favor the growth of a ceramic oxidation reaction product from the matrix metal (e.g., the matrix metal serves the dual role of a matrix metal and a parent metal for growth of oxidation reaction product). The growth of oxidation reaction product can occur from one or more surfaces of a metal matrix composite body and can be controlled to result in any desired shape. Moreover, the oxidation reaction product can be caused to grow directly into an atmosphere to form a ceramic body or can be caused to grow into an adjacently located filler material to form a ceramic matrix composite body. The oxidation reaction product can be formed substantially immediately after the metal matrix composite body is formed or may be formed at any point later in time.

摘要翻译： 本发明涉及一种制造大复合体的新方法。 具体地说，首先形成金属基体复合体，然后从已经形成的金属基体复合体的至少一个表面形成陶瓷体或陶瓷基复合体。 陶瓷或陶瓷复合体可以通过例如从自发渗透条件形成，这允许熔融基质金属渗透填料或预成型体以有利于从基体金属生长陶瓷氧化反应产物的条件（例如， ，基质金属起着基质金属和母体金属作为氧化反应产物生长的双重作用）。 氧化反应产物的生长可以从金属基质复合体的一个或多个表面发生，并且可以被控制以产生任何所需的形状。 此外，可以使氧化反应产物直接生长到大气中以形成陶瓷体，或者可以使其生长成相邻的填料，形成陶瓷基复合体。 氧化反应产物可以在形成金属基质复合体之后基本上立即形成，或者可以在任何时间点形成。

公开(公告)号：US20230172975A1

公开(公告)日：2023-06-08

申请号：US17708253

申请日：2022-03-30

申请人： Adam R. Dorfman ,  David A. Bryce ,  Maxwell A. Grace ,  D. Kyle Pierce ,  Mikhail Merzliakov ,  Mark G. Mortenson

发明人： Adam R. Dorfman ,  David A. Bryce ,  Maxwell A. Grace ,  D. Kyle Pierce ,  Mikhail Merzliakov ,  Mark G. Mortenson

IPC分类号： A61K33/243 ,  A61K9/14 ,  A61K9/10 ,  A61K33/242 ,  C22C1/04 ,  C22C5/02 ,  C22C5/04 ,  C22C30/00 ,  A61K9/16

CPC分类号： A61K33/243 ,  A61K9/14 ,  A61K9/10 ,  A61K33/242 ,  C22C1/0466 ,  C22C5/02 ,  C22C5/04 ,  C22C30/00 ,  A61K9/1611 ,  B82Y5/00

摘要： The present invention relates to novel gold-platinum based bi-metallic nanocrystal suspensions that have nanocrystal surfaces that are substantially free from organic or other impurities or films associated with typical chemical reductants/stabilizers and/or raw materials used in nanoparticle formation processes. Specifically, the surfaces are “clean” relative to the surfaces of metal-based nanoparticles made using chemical reduction (and other) processes that require organic (or other) reductants and/or surfactants to grow (and/or suspend) metal nanoparticles from metal ions in a solution.
The invention includes novel electrochemical manufacturing apparatuses and techniques for making the bi-metallic nanocrystal suspensions. The techniques do not require the use or presence of chlorine ions/atoms and/or chlorides or chlorine-based materials for the manufacturing process/final suspension. The invention further includes pharmaceutical compositions thereof and the use of the bi-metallic nanocrystals or suspensions or colloids thereof for the treatment or prevention of diseases or conditions for which metal-based therapy is already known, including, for example, for cancerous diseases or conditions.

公开(公告)号：US09387225B2

公开(公告)日：2016-07-12

申请号：US14008931

申请日：2012-03-30

申请人： Adam R. Dorfman ,  David A. Bryce ,  Maxwell A. Grace ,  D. Kyle Pierce ,  Mikhail Merzliakov ,  Mark G. Mortenson

发明人： Adam R. Dorfman ,  David A. Bryce ,  Maxwell A. Grace ,  D. Kyle Pierce ,  Mikhail Merzliakov ,  Mark G. Mortenson

IPC分类号： A61K33/24 ,  A61K9/14 ,  C22C1/04 ,  C22C5/02 ,  C22C5/04 ,  C22C30/00 ,  A61K9/10

CPC分类号： A61K33/24 ,  A61K9/10 ,  A61K9/14 ,  A61K9/1611 ,  B82Y5/00 ,  C22C1/0466 ,  C22C5/02 ,  C22C5/04 ,  C22C30/00

摘要： The present invention relates to novel gold-platinum based bi-metallic nanocrystal suspensions that have nanocrystal surfaces that are substantially free from organic or other impurities or films associated with typical chemical reductants/stabilizers and/or raw materials used in nanoparticle formation processes. Specifically, the surfaces are “clean” relative to the surfaces of metal-based nanoparticles made using chemical reduction (and other) processes that require organic (or other) reductants and/or surfactants to grow (and/or suspend) metal nanoparticles from metal ions in a solution. The invention includes novel electrochemical manufacturing apparatuses and techniques for making the bi-metallic nanocrystal suspensions. The techniques do not require the use or presence of chlorine ions/atoms and/or chlorides or chlorine-based materials for the manufacturing process/final suspension. The invention further includes pharmaceutical compositions thereof and the use of the bi-metallic nanocrystals or suspensions or colloids thereof for the treatment or prevention of diseases or conditions for which metal-based therapy is already known, including, for example, for cancerous diseases or conditions.

摘要翻译： 本发明涉及具有纳米晶体表面的新型金 - 铂基双金属纳米晶体悬浮液，其基本上不含与用于纳米颗粒形成过程中的典型化学还原剂/稳定剂和/或原料相关的有机或其它杂质或膜。 具体地说，相对于使用需要有机（或其它）还原剂和/或表面活性剂从金属生长（和/或悬浮）金属纳米粒子的化学还原（和其它）方法制备的金属基纳米颗粒的表面，表面“干净” 离子在溶液中。 本发明包括用于制备双金属纳米晶体悬浮液的新型电化学制造装置和技术。 这些技术不需要使用或存在氯离子/原子和/或氯化物或氯基材料用于制造过程/最终悬浮液。 本发明还包括其药物组合物，以及双金属纳米晶体或其悬浮液或胶体在治疗或预防金属基治疗已知的疾病或病症中的应用，包括例如癌性疾病或病症 。

公开(公告)号：US20130199922A1

公开(公告)日：2013-08-08

申请号：US13567334

申请日：2012-08-06

申请人： Juliana H. J. Brooks ,  Mark G. Mortenson ,  Beatley J. Blum

发明人： Juliana H. J. Brooks ,  Mark G. Mortenson ,  Beatley J. Blum

IPC分类号： B01J19/12

CPC分类号： B01J19/12 ,  B01D9/005 ,  B01D9/0063 ,  B01J19/121 ,  B01J19/122 ,  B01J19/127 ,  C01B3/0026 ,  C01B3/0031 ,  C01B5/00 ,  C01B13/0214 ,  C01D3/04 ,  C01D3/10 ,  C12N13/00 ,  Y02E60/327

摘要： This invention relates to novel methods for affecting, controlling and/or directing various reactions and/or reaction pathways or systems by exposing one or more components in a holoreaction system to at least one spectral energy pattern. In a first aspect of the invention, at least one spectral energy pattern can be applied to a reaction system. In a second aspect of the invention, at least one spectral energy conditioning pattern can be applied to a conditioning reaction system. The spectral energy conditioning pattern can, for example, be applied at a separate location from the reaction vessel (e.g., in a conditioning reaction vessel) or can be applied in (or to) the reaction vessel, but prior to other reaction system participants being introduced into the reaction vessel.The techniques of the present invention are applicable to inorganic reactions, organic reactions, biologic reactions and/or phase or structure change reactions. The invention specifically discloses different means for achieving the control of energy dynamics (e.g., matching or non-matching) between, for example, applied energy and matter (e.g., solids, liquids, gases, plasmas and/or combinations or portions thereof), to achieve (or to prevent) and/or increase energy transfer to, for example, at least one participant (or at least one conditionable participant) in a holoreaction system by taking into account various energy considerations in the holoreaction system. The invention also discloses an approach for designing or determining appropriate physical catalyst(s) to be used in a holoreaction system.The techniques of the present invention use targeted spectral energies to control transformation of matter, and/or reaction system dynamics, such as chemical reactions, phase changes, and material properties.

摘要翻译： 本发明涉及通过将一个或多个组合物暴露于至少一个光谱能量图案来影响，控制和/或指导各种反应和/或反应途径或系统的新方法。 在本发明的第一方面中，至少一种光谱能量图案可以应用于反应系统。 在本发明的第二方面，至少一种光谱能量调节模式可以应用于调理反应系统。 例如，光谱能量调节图案可以在与反应容器（例如在调节反应容器中）分开的位置处施加，或者可以应用于反应容器中（或到其中），但在其它反应系统参与者之前 引入反应容器。 本发明的技术适用于无机反应，有机反应，生物反应和/或相或结构变化反应。 本发明具体公开了用于实现例如施加的能量和物质（例如，固体，液体，气体，等离子体和/或其组合或部分）之间的能量动力学（例如，匹配或不匹配）的控制的不同手段， 通过考虑到holoreaction系统中的各种能量考虑，实现（或预防）和/或增加到例如hoiledaction系统中的至少一个参与者（或至少一个有条件的参与者）的能量转移。 本发明还公开了一种用于设计或确定在holoaction系统中使用的合适的物理催化剂的方法。 本发明的技术使用目标光谱能量来控制物质的转化和/或反应系统动力学，例如化学反应，相变和材料性质。

公开(公告)号：US08048274B2

公开(公告)日：2011-11-01

申请号：US10507659

申请日：2003-03-11

申请人： Juliana H. J. Brooks ,  Mark G. Mortenson ,  Bentley J. Blum

发明人： Juliana H. J. Brooks ,  Mark G. Mortenson ,  Bentley J. Blum

IPC分类号： C07C1/00 ,  C25B5/00 ,  H01M2/00 ,  C25B1/00

CPC分类号： C12N13/00 ,  B01D9/005 ,  B01D9/0063 ,  B01J19/121 ,  B01J19/122 ,  B01J19/127 ,  C01B3/0026 ,  C01B3/0031 ,  C01B5/00 ,  C01B13/0214 ,  C01D3/04 ,  Y02E60/327

摘要： The invention relates to novel methods for affecting, controlling and/or directing various reactions and/or reaction pathways or systems by exposing one or more components in a holoreaction system to at least one spectral energy pattern. In a first aspect of the invention, at least one spectral energy pattern can be applied to a reaction system. In a second aspect of the invention, at least one spectral energy conditioning pattern can be applied to a conditioning reaction system. The spectral energy conditioning pattern can, for example, be applied at a separate location from the reaction vessel (e.g., in a conditioning reaction vessel) or can be applied in (or to) the reaction vessel, but prior to other reaction system participants being introduced into the reaction vessel.

摘要翻译： 本发明涉及通过将一种或多种组合物暴露于至少一种光谱能量图案来影响，控制和/或指导各种反应和/或反应途径或系统的新方法。 在本发明的第一方面中，至少一种光谱能量图案可以应用于反应系统。 在本发明的第二方面，至少一种光谱能量调节模式可以应用于调理反应系统。 例如，光谱能量调节图案可以在与反应容器（例如在调节反应容器中）分开的位置处施加，或者可以应用于反应容器中（或到其中），但在其它反应系统参与者之前 引入反应容器。

公开(公告)号：US20100187091A1

公开(公告)日：2010-07-29

申请号：US12686815

申请日：2010-01-13

申请人： David Kyle Pierce ,  Mark G. Mortenson ,  David A. Bryce

发明人： David Kyle Pierce ,  Mark G. Mortenson ,  David A. Bryce

IPC分类号： B22F9/16 ,  H05H1/24 ,  B01J19/08

CPC分类号： H05H1/48 ,  B01J19/088 ,  B01J2219/0004 ,  B01J2219/0809 ,  B01J2219/0813 ,  B01J2219/082 ,  B01J2219/083 ,  B01J2219/0841 ,  B01J2219/0869 ,  B01J2219/0871 ,  B01J2219/0877 ,  B22F9/20 ,  B22F2999/00 ,  B82Y30/00 ,  B82Y40/00 ,  B22F2202/06 ,  B22F2202/13

摘要： This invention relates generally to novel methods and novel devices for the continuous manufacture of nanoparticles, microparticles and nanoparticle/liquid solution(s). The nanoparticles (and/or micron-sized particles) comprise a variety of possible compositions, sizes and shapes. The particles (e.g., nanoparticles) are caused to be present (e.g., created and/or the liquid is predisposed to their presence (e.g., conditioned)) in a liquid (e.g., water) by, for example, preferably utilizing at least one adjustable plasma (e.g., created by at least one AC and/or DC power source), which plasma communicates with at least a portion of a surface of the liquid. At least one subsequent and/or substantially simultaneous adjustable electrochemical processing technique is also preferred. Multiple adjustable plasmas and/or adjustable electrochemical processing techniques are preferred. The continuous process causes at least one liquid to flow into, through and out of at least one trough member, such liquid being processed, conditioned and/or effected in said trough member(s). Results include constituents formed in the liquid including micron-sized particles and/or nanoparticles (e.g., metallic-based nanoparticles) of novel size, shape, composition, zeta potential and properties present in a liquid.

摘要翻译： 本发明一般涉及用于连续制造纳米颗粒，微粒和纳米颗粒/液体溶液的新颖方法和新型装置。 纳米颗粒（和/或微米尺寸的颗粒）包含各种可能的组合物，尺寸和形状。 引起颗粒（例如，纳米颗粒）存在（例如，通过例如优选利用至少一种的方式在液体（例如水）中存在（例如，产生和/或将液体倾向于其存在（例如，调节）） 可调节的等离子体（例如，由至少一个AC和/或DC电源产生），其等离子体与液体的至少一部分表面连通。 至少一个后续和/或基本上同时可调节的电化学处理技术也是优选的。 多重可调等离子体和/或可调电化学处理技术是优选的。 连续过程使至少一种液体流入，通过和流出至少一个槽构件，这种液体在所述槽构件中被处理，调节和/或实现。 结果包括在液体中形成的成分，包括具有新颖尺寸，形状，组成，ζ电位和存在于液体中的性质的微米级颗粒和/或纳米颗粒（例如金属基纳米颗粒）。

公开(公告)号：US07701808B2

公开(公告)日：2010-04-20

申请号：US12025413

申请日：2008-02-04

申请人： Juliana H. J. Brooks ,  Mark G. Mortenson

发明人： Juliana H. J. Brooks ,  Mark G. Mortenson

IPC分类号： G11B11/00

CPC分类号： G11B5/00 ,  B82Y10/00 ,  B82Y25/00 ,  G11B5/012 ,  G11B5/02 ,  G11B5/09 ,  G11B7/00 ,  G11B7/00455 ,  G11B7/0052 ,  G11B7/0065 ,  G11B7/127 ,  G11B7/128 ,  G11B7/1381 ,  G11B7/24088 ,  G11B9/00 ,  G11B2005/0002 ,  G11B2005/3996 ,  G11C13/06

摘要： The present invention relates generally to the storage of information on magnetic and/or optical storage media by using one or more novel approaches alone or in combination. These novel approaches are capable of using at least one code which may comprise more than two values (i.e., more than a “0” and a “1”). A first series of approaches for the storage of information applies generally to optical storage/retrieval systems (e.g., CD's, DVD's, etc.); while a second series of approaches applies generally to electric and/or magnetic storage/retrieval systems (e.g., magnetic, magneto-optic, etc.). Each series of approaches is capable of storing information in one or more codes, wherein such approaches permit, if desired, the use of at least one higher order code which is different from the traditional binary code of “0's” and “1's” currently utilized for the storage of digital information. Said at least one higher order code may comprise three or more optical and/or magnetic values or bits that are used to represent, for example, ASCII or Unicode characters that are currently represented predominantly by the traditional binary code. This higher order code may also be an analog or analog-like code.

摘要翻译： 本发明一般涉及通过单独或组合使用一种或多种新颖方法来存储关于磁性和/或光学存储介质的信息。 这些新颖的方法能够使用至少一个可以包括多于两个值（即大于“0”和“1”）的代码。 用于存储信息的第一系列方法通常适用于光学存储/检索系统（例如CD，DVD等）; 而第二系列方法通常适用于电和/或磁存储/检索系统（例如，磁性，磁光学等）。 每一系列方法能够将信息存储在一个或多个代码中，其中如果需要，这样的方法允许使用与当前使用的“0”和“1”的传统二进制代码不同的至少一个更高阶代码 用于存储数字信息。 所述至少一个较高阶代码可以包括用于表示例如主要由传统二进制代码表示的ASCII或Unicode字符的三个或更多个光学和/或磁性值或位。 该较高阶代码也可以是模拟或类似模拟的代码。

公开(公告)号：US20090253002A1

公开(公告)日：2009-10-08

申请号：US12333929

申请日：2008-12-12

申请人： Juliana H. J. Brooks ,  Bentley J. Blum ,  Mark G. Mortenson

发明人： Juliana H. J. Brooks ,  Bentley J. Blum ,  Mark G. Mortenson

IPC分类号： H01M8/04

CPC分类号： H01M8/0606 ,  B01J19/121 ,  B01J19/122 ,  B01J19/127 ,  B01J23/42 ,  B01J37/344 ,  C01B3/0026 ,  C01B3/0031 ,  C01B5/00 ,  C01B13/0214 ,  C01D3/04 ,  C01D3/10 ,  H01M4/90 ,  H01M8/00 ,  H01M8/16 ,  Y02E60/327 ,  Y02E60/527 ,  Y02P20/135

摘要： This invention relates to novel methods for affecting, controlling and/or directing various reactions and/or reaction pathways or systems by exposing one or more components in a fuel cell reaction system to at least one spectral energy pattern. In a first aspect of the invention, at least one spectral energy pattern can be applied to a fuel cell reaction system. In a second aspect of the invention, at least one spectral energy conditioning pattern can be applied to a conditioning reaction system. The spectral energy conditioning pattern can, for example, be applied at a separate location from the reaction vessel (e.g., in a conditioning reaction vessel) or can be applied in (or to) the reaction vessel, but prior to other reaction system participants being introduced into the reaction vessel.

摘要翻译： 本发明涉及通过将燃料电池反应系统中的一种或多种组分暴露于至少一种光谱能量图案来影响，控制和/或指导各种反应和/或反应途径或系统的新方法。 在本发明的第一方面中，至少一种光谱能量图案可以应用于燃料电池反应系统。 在本发明的第二方面，至少一种光谱能量调节模式可以应用于调理反应系统。 例如，光谱能量调节图案可以在与反应容器（例如在调节反应容器中）分开的位置处施加，或者可以应用于反应容器中（或到其中），但在其它反应系统参与者之前 引入反应容器。