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251 条记录 (耗时 0.062 秒)

    TRIAZOLONE DERIVATIVES AS MMP INHIBITORS FOR THE TREATMENT OF ASTHMA AND COPD
    22.
    发明申请
    TRIAZOLONE DERIVATIVES AS MMP INHIBITORS FOR THE TREATMENT OF ASTHMA AND COPD 审中-公开
    作为治疗哮喘和COPD的MMP抑制剂的三唑酮衍生物

    公开(公告)号：US20090299066A1

    公开(公告)日：2009-12-03

    申请号：US12538522

    申请日：2009-08-10

    申请人： Anders Eriksson ,  Matti Lepistö

    发明人： Anders Eriksson ,  Matti Lepistö

    IPC分类号： C07D401/06

    CPC分类号： C07D249/12 ,  C07D401/12 ,  C07D401/14 ,  C07D417/14 ,  C07D491/10

    摘要： The invention provides compounds of formula (I): wherein R1, R2, R3, R4, R5, X, Y, L, G1 and m have the meanings defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceuticals compositions; and their use in therapy. The compounds are useful as metalloproteinase (MMP) inhibitors.

    摘要翻译： 本发明提供式（I）化合物：其中R1，R2，R3，R4，R5，X，Y，L，G1和m具有本说明书中定义的含义; 其准备过程; 含有它们的药物组合物; 制备药物组合物的方法; 及其在治疗中的应用。 该化合物可用作金属蛋白酶（MMP）抑制剂。

    Method for Determining the Activity of a Protease in a Sample
    24.
    发明申请
    Method for Determining the Activity of a Protease in a Sample 审中-公开
    测定样品中蛋白酶活性的方法

    公开(公告)号：US20100021940A1

    公开(公告)日：2010-01-28

    申请号：US12296568

    申请日：2007-04-11

    申请人： Anders Blomgren ,  Anders Eriksson ,  Thomas Hansson ,  Keith Jolley ,  Matti Lepisto ,  Karin Von Wachenfeldt

    发明人： Anders Blomgren ,  Anders Eriksson ,  Thomas Hansson ,  Keith Jolley ,  Matti Lepisto ,  Karin Von Wachenfeldt

    IPC分类号： C12Q1/37 ,  G01N33/573 ,  C07K2/00 ,  C07C205/00

    CPC分类号： C12Q1/37 ,  G01N2333/96486 ,  G01N2500/00 ,  G01N2800/122

    摘要： There is provided a method for determining the activity of a protease in a sample. The method comprises (i) admixing said sample with a substrate, wherein the substrate has the formula (1a) wherein: R1 is a hydrocarbyl group; R2 is a first peptide moiety; R3 is a second peptide moiety and X is selected from the group consisting of O, S and NH; Y1 is a suitable substituent; Y2 is a suitable substituent; and (ii) determining the activity of said protease by detecting the presence of a reporter having the formula H—X—R1, wherein: X is selected from the group consisting of O, S and NH; R1 is a hydrocarbyl group. The substrate and reporter are useful for determining the efficacy of protease-modulators and candidate protease-modulators and in the diagnosis of a disease or disorder in a subject.

    摘要翻译： 提供了测定样品中蛋白酶活性的方法。 该方法包括（i）将所述样品与基底混合，其中基底具有式（1a），其中：R1是烃基; R2是第一个肽部分; R3是第二肽部分，X选自O，S和NH; Y1是合适的取代基; Y2是合适的取代基; 和（ii）通过检测存在具有式H-X-R1的报告基来确定所述蛋白酶的活性，其中：X选自O，S和NH; R1是烃基。 底物和报告物可用于确定蛋白酶调节剂和候选蛋白酶调节剂的功效以及受试者中疾病或病症的诊断。

    Client and a method in a client in a communication network for providing a service
    25.
    发明授权
    Client and a method in a client in a communication network for providing a service 有权

    公开(公告)号：US09661032B2

    公开(公告)日：2017-05-23

    申请号：US13991740

    申请日：2010-12-14

    申请人： Marcus Nyberg ,  Bo Burman ,  Anders Eriksson

    发明人： Marcus Nyberg ,  Bo Burman ,  Anders Eriksson

    IPC分类号： G06F15/16 ,  H04L29/06 ,  H04W4/02

    CPC分类号： H04L65/1069 ,  H04L69/24 ,  H04W4/023

    摘要： A client and a method in a client in a communication network comprising a core network, for providing a communication service, is provided. The method comprises receiving a session setup request from an originating party, requesting a session with a destination party. The setup request comprises a capability indication associated with the originating party and a session type indication. The method further comprises determining capabilities of devices in a first communication context associated with the destination party and comparing the capabilities of the devices in the first communication context to the capability indication and to the session type indication in the received request Still further, the method comprises determining a level of correspondence between the capability indication and the session type indication, and the capabilities of devices in the first communication context, and indicating a device in the first communication context having a suitable level of correspondence to the capability indication associated with the originating party and the session type indication.

    Furniture joint
    26.
    发明授权
    Furniture joint 有权
    家具联合

    公开(公告)号：US09534623B2

    公开(公告)日：2017-01-03

    申请号：US14371877

    申请日：2012-01-13

    申请人： Benny Anderson ,  Anders Eriksson ,  Göran Sjöstedt

    发明人： Benny Anderson ,  Anders Eriksson ,  Göran Sjöstedt

    IPC分类号： F16B12/12 ,  F16B12/22 ,  F16B12/46 ,  A47B96/06 ,  A47B47/04

    CPC分类号： F16B12/125 ,  A47B47/042 ,  A47B96/066 ,  F16B12/22 ,  F16B12/46 ,  F16B2012/463 ,  F16B2012/466 ,  Y10T403/7015 ,  Y10T403/7045

    摘要： A joint for assembling two furniture parts to each other. A first furniture part has a male part for co-operation with a female part of a second furniture part. Each of the male and female parts has a number of grooves. At assembly the male part is moved along the female part via co-operation between the grooves of the male and female part, respectively. The co-operating male and female parts have an insertion position and an end position, in which end position the furniture parts are assembled to each other. The grooves of one of the female and male parts are compressed during movement from the insertion position to the end position. The grooves of the pair of co-operating female part and male part are such that the furniture parts are pressed toward each other when the male part is moved along the female part.

    摘要翻译： 用于组装两个家具部件的接头。 第一家具部件具有用于与第二家具部件的女性部分配合的男性部件。 每个男性和女性部分都有多个凹槽。 在组装时，阳部分分别通过公件和阴部件的凹槽之间的协作而沿着凹形部件移动。 配合的男性和女性部件具有插入位置和终止位置，其中家具部件的端部位置彼此组装。 在从插入位置到结束位置的运动期间，凹部和凹部中的一个凹槽被压缩。 一对配合的阴部件和阳部件的凹槽使得当阳部件沿着阴部件移动时，家具部件被相互挤压。

    Arrangement and method for adapting a cruise control system in a vehicle
    27.
    发明授权
    Arrangement and method for adapting a cruise control system in a vehicle 有权
    适应车辆巡航控制系统的布置和方法

    公开(公告)号：US09233690B2

    公开(公告)日：2016-01-12

    申请号：US14349340

    申请日：2011-10-05

    申请人： Anders Eriksson ,  Johan Bjernetun

    发明人： Anders Eriksson ,  Johan Bjernetun

    IPC分类号： B60T8/32 ,  B60W30/14 ,  B60K31/06 ,  B60W50/08 ,  B60K31/00

    CPC分类号： B60W30/143 ,  B60K31/06 ,  B60K2031/0091 ,  B60K2310/244 ,  B60W50/082 ,  B60W2540/04 ,  Y02T10/52 ,  Y02T10/84

    摘要： A cruise control arrangement for a vehicle includes a cruise control speed function, a cruise control brake function and at least one selectable economy level, having a set maximum speed value corresponding to a maximum allowed vehicle speed, a set brake speed value corresponding to a brake cruise speed and a set cruise speed value corresponding to a cruise speed, where a temporary brake speed value replaces the set brake speed value as the actually used brake speed value, and where the temporary brake speed value is dependent on the selected economy level. The behavior of the cruise control of a vehicle can be adapted to take account of economy, which makes it possible to optimize the fuel consumption of the vehicle.

    摘要翻译： 用于车辆的巡航控制装置包括巡航控制速度功能，巡航控制制动功能和至少一个可选经济水平，具有对应于最大允许车速的设定最大速度值，对应于制动器的设定制动速度值 巡航速度和对应于巡航速度的设定巡航速度值，其中临时制动速度值代替设定的制动速度值作为实际使用的制动速度值，并且临时制动速度值取决于所选经济水平。 车辆的巡航控制的行为可以适应于考虑到经济性，这使得可以优化车辆的燃料消耗。

    System and method for providing differentiated services
    28.
    发明授权
    System and method for providing differentiated services 有权
    提供差异化​​服务的系统和方法

    公开(公告)号：US09154429B2

    公开(公告)日：2015-10-06

    申请号：US10548187

    申请日：2004-03-05

    申请人： Anders Eriksson ,  Börje Ohlman ,  Wei Zhao

    发明人： Anders Eriksson ,  Börje Ohlman ,  Wei Zhao

    IPC分类号： H04L12/801 ,  H04L12/851 ,  G06F15/16 ,  H04L12/853 ,  H04L12/891

    CPC分类号： H04L47/2416 ,  H04L47/10 ,  H04L47/2408 ,  H04L47/2425 ,  H04L47/41 ,  Y02D50/30

    摘要： The present invention relates to a method and arrangements for updating the mapping of traffic in the form of a set of service level aggregate flows (SLS1, SLSM) to a set of partial resources (B1, BN) for forwarding the traffic in a communications network (21). Each service level aggregate flow corresponds to a service level associated with a set of service requirements. Information regarding traffic characteristics of each service level aggregate flow and performance of the set of network resources are obtained. Based on this information, the mapping of the set of service level aggregate flows to the set of network resources is updated to achieve a more efficient utilization of the set of network resources, while fulfilling the set of service requirements.

    摘要翻译： 本发明涉及以一组业务级别聚合流（SLS1，SLSM）的形式更新业务映射的方法和装置，用于在通信网络中转发业务的部分资源（B1，BN） （21）。 每个服务级聚合流对应于与一组服务要求相关联的服务级别。 获得关于每个服务级别的流量特性聚合流量和网络资源集合的性能的信息。 基于该信息，更新服务级聚合流集合到网络资源集合的映射，以在满足一组服务需求的同时实现对该组网络资源的更有效的利用。

    Refresh requests in soft-state signalling
    30.
    发明授权
    Refresh requests in soft-state signalling 有权
    在软状态信令中刷新请求

    公开(公告)号：US08996703B2

    公开(公告)日：2015-03-31

    申请号：US13130848

    申请日：2008-11-25

    申请人： Anders Eriksson

    发明人： Anders Eriksson

    IPC分类号： H04L29/08 ,  H04W52/02 ,  H04W56/00 ,  H04L29/06 ,  G06F13/16

    CPC分类号： H04W52/0216 ,  G06F13/1689 ,  H04L67/145 ,  H04L69/28 ,  H04W52/0219 ,  H04W52/0248 ,  H04W56/00 ,  Y02D70/00

    摘要： A power-saving synchronization of refresh requesting messages transmitted from a client terminal (31) to different server terminals (33a, 33b) in multiple soft-state dialogues, e.g. in SIP. The synchronization involves a continuous detection of a large time offset (34) occurring between the refresh requesting messages in the different dialogues, and an adjustment of the negotiated length of the refresh interval indicated in the refresh requesting messages, such that the client terminal will transmit the refresh requesting messages approximately simultaneously to the different server terminals.

    摘要翻译： 在多个软状态对话中，例如从客户终端（31）发送到不同服务器终端（33a，33b）的刷新请求消息的省电同步。 在SIP中。 同步涉及在不同对话中的刷新请求消息之间发生的大的时间偏移（34）的连续检测以及刷新请求消息中指示的刷新间隔的协商长度的调整，使得客户终端将发送 刷新请求消息大致同时到不同的服务器终端。