公开(公告)号：US20110262453A1

公开(公告)日：2011-10-27

申请号：US13059931

申请日：2009-08-20

申请人： Samir E. Witta ,  Koichi Yoshida ,  Rafal Dziadziuszko ,  Fred R. Hirsch

发明人： Samir E. Witta ,  Koichi Yoshida ,  Rafal Dziadziuszko ,  Fred R. Hirsch

IPC分类号： A61K39/395 ,  A61P35/00 ,  A61K38/45 ,  C12Q1/02

CPC分类号： C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/158 ,  G01N33/57484 ,  G01N2333/705 ,  G01N2333/71 ,  G01N2800/52

摘要： The present invention relates to a method of predicting response of a cancer cell tissue to IGF-IR treatment. The inventors have observed a direct relationship between the expression of survivin, ErbB3 and E-cadherin and the response of cancer cells to IGF-IR treatment. This observation permits screening of tumor cells prior to treatment to determine whether the cancer will respond to IGF-IR treatment, and/or to monitor the efficacy of such a treatment by conducting “before and after” assessments of the expression of these markers

摘要翻译： 本发明涉及预测癌细胞组织对IGF-1R治疗的反应的方法。 本发明人观察到存活蛋白，ErbB3和E-钙粘蛋白的表达与癌细胞对IGF-1R处理的反应之间存在直接关系。 该观察允许在治疗之前筛选肿瘤细胞以确定癌症是否将响应于IGF-1R治疗，和/或通过对这些标记物的表达进行“前后”评估来监测这种治疗的功效

公开(公告)号：US07315110B2

公开(公告)日：2008-01-01

申请号：US11167912

申请日：2005-06-28

申请人： Koichi Yoshida

发明人： Koichi Yoshida

IPC分类号： H01T13/20

CPC分类号： H01T13/38 ,  H01T13/20

摘要： A spark plug according to the invention has a length and an outer side surface. The outer side surface includes a plurality of closed band-shaped regions arranged in the lengthwise direction of the spark plug, within each of which a plurality of identical marks, which represent the same piece of information concerning the spark plug, are formed at predetermined intervals in a circumferential direction of the spark plug. Further, the marks within each of the regions represent the piece of information different from that represented by the marks within any other one of the regions, and each of the marks within each of the regions is aligned in the lengthwise direction of the spark plug with one of the marks within any other one of the regions. With such formation of marks, the spark plug can be accurately identified without rotating it to a specific position during the identification process.

摘要翻译： 根据本发明的火花塞具有长度和外侧表面。 外侧表面包括沿着火花塞的长度方向布置的多个封闭带状区域，其中分别形成表示与火花塞相关的信息的多个相同的标记，并以预定间隔形成 在火花塞的圆周方向上。 此外，每个区域内的标记表示与该区域内的标记不同的信息，并且每个区域内的每个标记在火花塞的长度方向上对齐， 任何其他地区之一的标记之一。 通过这种标志的形成，可以在识别过程中将火花塞精确地识别而不将其旋转到特定位置。

公开(公告)号：US07275551B2

公开(公告)日：2007-10-02

申请号：US10258526

申请日：2001-04-12

申请人： Takafumi Kanaya ,  Kazuhisa Okada ,  Koichi Yoshida

发明人： Takafumi Kanaya ,  Kazuhisa Okada ,  Koichi Yoshida

IPC分类号： B08B3/00 ,  B08B3/06

CPC分类号： A23L3/3409 ,  A23B7/157 ,  A23B7/158 ,  A23B9/30 ,  A23L3/358 ,  A23L3/3589 ,  A23N12/02 ,  Y02A40/922

摘要： A food washing apparatus of the invention includes an ozonized water generator (10), a cylindrical washing tank (1) in which the food materials are put and which can rotate to wash the food materials, a drainage part (4) formed at a part of the washing tank (1) and including openings to such a degree that water passes through and the food materials do not pass through, and wash water pipings (2, 9) which are inserted and disposed in the washing tank (1) in an axial direction and in which water spray holes (2a, 2a) for spraying wash water including at least ozonized water are formed, and while at least one part of the wash water sprayed from the wash water pipings (2, 9) is draind from the washing tank (1) every rotation of the washing tank (1), washing of the food materials is performed. Further, there is also a method in which a receiving tank (8) for wash water drained from the washing tank (1) is provided, and at least one part of the wash water in the receiving tank (8) is returned to an inlet side of the ozonized water generator (10) to perform cyclic use of the wash water.

摘要翻译： 本发明的饮食洗涤装置包括臭氧水发生器（10），其中放置食物材料并可旋转以洗涤食物的圆筒形洗涤罐（1），形成在部分上的排出部分（4） 并且包括开口，使得水通过并且食品材料不通过的程度，并且将洗涤槽（1）中插入和设置的水管（2,9）清洗在 并且其中形成用于喷射包括至少臭氧化水的洗涤水的喷水孔（2a，2a），并且在从洗涤水管道（2,9）喷射的洗涤水的至少一部分被排出 从清洗槽（1）洗涤槽（1）旋转一周后，进行食品的清洗。 此外，还提供了一种从洗涤槽（1）排出的用于洗涤水的接收罐（8）的方法，并且容纳罐（8）中的洗涤水的至少一部分返回到入口 臭氧化水发生器（10）的一侧以循环使用洗涤水。

公开(公告)号：US20070216278A1

公开(公告)日：2007-09-20

申请号：US11717788

申请日：2007-03-14

申请人： Koichi Yoshida

发明人： Koichi Yoshida

IPC分类号： H01T13/20

CPC分类号： H01T13/20 ,  H01T13/32 ,  H01T13/36 ,  H01T13/39

摘要： A spark plug is disclosed as having a metal shell, a porcelain insulator fixedly secured to the metal shell, a center electrode and a ground electrode providing a spark discharge gap with the center electrode. The porcelain insulator has a through-bore partially exposed from an end face of the ground electrode in a surface area S1, as viewed from a distal end of the spark plug, and having a total surface area S2 falling in the relationship S1/S2≦0.3. The center electrode protrudes from the porcelain insulator with a protruding length L under the relationship L≦0.6 mm. A minimal value Hmin and a maximal value Hmax in distance between the ground electrode and the end face of the porcelain insulator lies in the relationship Hmax/Hmin≦1.3. Wall thickness T between the through-bore and an outer periphery of the porcelain insulator lies in the relationship T≦0.7 mm.

摘要翻译： 公开了一种火花塞，其具有金属壳，固定在金属壳上的瓷绝缘体，中心电极和与中心电极提供火花放电间隙的接地电极。 陶瓷绝缘体从火花塞的远端观察时，在表面区域S1中从接地电极的端面部分地露出贯通孔，总表面积S 2处于关系S 1 / S 2 <= 0.3。 中心电极以L <= 0.6mm的关系从瓷绝缘体突出长度为L。 接地电极与陶瓷绝缘体端面之间的距离最小值Hmin和最大值Hmax在Hmax / Hmin <= 1.3之间。 通孔与陶瓷绝缘体的外周之间的壁厚T在T <= 0.7mm的关系中。

公开(公告)号：US20050191838A1

公开(公告)日：2005-09-01

申请号：US11114084

申请日：2005-04-26

申请人： Shoriki Narita ,  Koichi Yoshida ,  Masahiko Ikeya ,  Takaharu Mae ,  Shinji Kanayama ,  Makoto Imanishi ,  Kazushi Higashi ,  Kenji Fukumoto ,  Hiroshi Wada

发明人： Shoriki Narita ,  Koichi Yoshida ,  Masahiko Ikeya ,  Takaharu Mae ,  Shinji Kanayama ,  Makoto Imanishi ,  Kazushi Higashi ,  Kenji Fukumoto ,  Hiroshi Wada

IPC分类号： H05K3/34 ,  B23K20/00 ,  H01L21/00 ,  H01L21/60 ,  H01L21/44

CPC分类号： H01L24/742 ,  H01L21/67138 ,  H01L21/67144 ,  H01L21/67248 ,  H01L24/11 ,  H01L2224/05568 ,  H01L2224/05573 ,  H01L2224/1134 ,  H01L2224/13099 ,  H01L2224/13144 ,  H01L2224/45144 ,  H01L2924/01004 ,  H01L2924/01006 ,  H01L2924/01013 ,  H01L2924/01023 ,  H01L2924/01025 ,  H01L2924/01033 ,  H01L2924/01039 ,  H01L2924/01047 ,  H01L2924/01052 ,  H01L2924/01065 ,  H01L2924/01073 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/01327 ,  H01L2924/10329 ,  H01L2924/351 ,  Y10T29/4921 ,  H01L2924/00 ,  H01L2924/00014

摘要： A preheat device (160) is provided to execute, before forming bumps (16) to electrode parts (15), a pre-formation temperature control for bonding promotion to promote bonding between the electrode parts and the bumps during bump formation. Metal particles of the electrode parts can be changed to an appropriate state before the bump formation. Phenomenally, a bonding state between the electrode parts and the bumps can be improved as compared with the conventional art. In a further arrangement of the present invention, semiconductor components with bumps can be heated under a bonding strength improvement condition by a bonding stage (316) through controlling the heating by a controller (317).

摘要翻译： 提供预热装置（160），用于在形成凸起（16）到电极部件（15）之前执行用于粘接促进的预制温度控制，以促进在凸起形成期间电极部件和凸块之间的接合。 电极部分的金属颗粒可以在凸点形成之前变成适当的状态。 与现有技术相比，现在可以改善电极部分和凸块之间的结合状态。 在本发明的另一方面中，通过控制器（317）的加热来控制加热，可以通过接合台（316）在接合强度改善条件下加热具有凸块的半导体部件。

公开(公告)号：US06481616B2

公开(公告)日：2002-11-19

申请号：US09978872

申请日：2001-10-17

申请人： Makoto Imanishi ,  Akihiro Yamamoto ,  Hiroyuki Otani ,  Shinzo Eguchi ,  Takahiro Yonezawa ,  Kazushi Higashi ,  Koichi Yoshida ,  Kouji Hirotani

发明人： Makoto Imanishi ,  Akihiro Yamamoto ,  Hiroyuki Otani ,  Shinzo Eguchi ,  Takahiro Yonezawa ,  Kazushi Higashi ,  Koichi Yoshida ,  Kouji Hirotani

IPC分类号： B23K3102

CPC分类号： H01L21/68 ,  H01L21/321 ,  H01L24/11 ,  H01L24/81 ,  H01L2224/13099 ,  H01L2224/45144 ,  H01L2224/81205 ,  H01L2224/81801 ,  H01L2924/01004 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01027 ,  H01L2924/01033 ,  H01L2924/01039 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/14 ,  H01L2924/00

摘要： To eliminate breakage of electronic parts or defective bonding, and enhance reliability of electronic parts, in regulation of electronic parts in bump bonding device. A bump bonding device comprising a stage 1 for mounting and heating an electronic part, and a position regulating device including a rotatable regulating plate 2 having a side for positioning the electronic part, a plate 4 having a side for positioning the electronic part in collaboration with the regulating plate, and a regulating spring 5 for applying a regulating force to the regulating plate in order to press the electronic part to the plate 4.

摘要翻译： 为了消除电子零件的破损或接合不良，提高电子零件的可靠性，在凸块焊接装置中调节电子部件。 一种凸块接合装置，包括用于安装和加热电子部件的台架1和包括具有用于定位电子部件的侧面的可旋转调节板2的位置调节装置，具有用于与电子部件配合的侧面的板4 调节板和用于向调节板施加调节力以便将电子部件按压到板4的调节弹簧5。

公开(公告)号：US6096542A

公开(公告)日：2000-08-01

申请号：US875944

申请日：1997-08-07

申请人： Kei Fujinaga ,  Koichi Yoshida ,  Fumihiro Higashino

发明人： Kei Fujinaga ,  Koichi Yoshida ,  Fumihiro Higashino

IPC分类号： A61K38/00 ,  A61K48/00 ,  C07K14/075 ,  C07K14/82 ,  C12Q1/68 ,  G01N33/574 ,  G01N33/74 ,  C12N15/09 ,  C07H21/04

CPC分类号： C07K14/005 ,  C07K14/82 ,  C12Q1/6886 ,  G01N33/57484 ,  G01N33/74 ,  A61K38/00 ,  A61K48/00 ,  C12N2710/10322 ,  C12Q2600/112 ,  C12Q2600/158

摘要： Clarification of the relationship between the functions of E1AF gene and the invasion and metastasis of cancers, and application thereof to cancer control, more specifically the control of cancer cell invasion by controlling the expression of E1AF gene and the products of expression, and the detection and diagnosis of cancers by detecting the products of expression of E1AF gene.

摘要翻译： PCT No.PCT / JP96 / 00016 Sec。 371日期1997年7月8日 102（e）日期1997年7月8日PCT提交1996年1月9日PCT公布。 公开号WO96 / 24379 日期：1996年8月15日E1AF基因功能与癌症侵袭转移之间的关系及其在癌症控制中的应用，更具体地说是通过控制E1AF基因和表达产物的表达来控制癌细胞侵袭 通过检测E1AF基因表达产物，检测和诊断癌症。

公开(公告)号：US6052893A

公开(公告)日：2000-04-25

申请号：US077670

申请日：1998-06-03

申请人： Koichi Yoshida ,  Tetsuo Fukushima ,  Kenichiro Suetsugu

发明人： Koichi Yoshida ,  Tetsuo Fukushima ,  Kenichiro Suetsugu

IPC分类号： B29C45/14 ,  B29C70/68 ,  B29L31/34 ,  C08L83/00 ,  C08L83/02 ,  C09D201/00 ,  H01L21/56 ,  H01L23/29 ,  H01L23/31 ,  H05K3/28 ,  A05K3/30

CPC分类号： H05K3/284 ,  B29C45/14639 ,  B29C45/14655 ,  B29C45/14836 ,  B29C70/683 ,  H01L21/565 ,  H01L23/3135 ,  H01L2924/0002 ,  Y10T29/49002 ,  Y10T29/49004 ,  Y10T29/4913 ,  Y10T29/49146

摘要： The present invention provides a method of manufacturing a small electronic component, by which its yield can be enhanced. The invention comprises the steps of: a component mounting step of mounting a necessary electronic component 2-4 on a substrate 1; a coating layer forming step of forming a coating layer 14 for covering and sealing the substrate 1 in its entirety including the electronic component 2-4 with a coating material having high heat resistance; and a package layer forming step of forming a package layer 17 for covering and sealing a circumference of the coating layer 14 with a thermoplastic resin material 12. In the package layer forming step, adverse effects by the heat from the thermoplastic resin 12 to the electronic components 2-4 and the substrate 1 are inhibited with the coating layer 14.

摘要翻译： PCT No.PCT / JP96 / 03578 Sec。 371日期1998年6月3日第 102（e）1998年6月3日PCT PCT 1996年12月6日PCT公布。 公开号WO97 / 20673 日期：1997年6月12日本发明提供一种小型电子部件的制造方法，能够提高其收率。 本发明包括以下步骤：将必要的电子部件2-4安装在基板1上的部件安装步骤; 涂覆层形成步骤，形成涂覆层14，用于利用具有高耐热性的涂层材料来覆盖和密封包括电子部件2-4的基板1整体; 以及封装层形成步骤，用热塑性树脂材料12形成用于覆盖和密封涂层14的周围的封装层17.在封装层形成步骤中，由热塑性树脂12的热量到电子 组件2-4和衬底1被涂层14抑制。

公开(公告)号：US4540449A

公开(公告)日：1985-09-10

申请号：US584996

申请日：1984-03-01

申请人： Koichi Yoshida ,  Yoshio Hirayama ,  Yasuo Oka ,  Takashi Kajiyama ,  Kunihiko Hotta

发明人： Koichi Yoshida ,  Yoshio Hirayama ,  Yasuo Oka ,  Takashi Kajiyama ,  Kunihiko Hotta

IPC分类号： G11B5/82 ,  C22C21/06 ,  C25D11/04 ,  C25D11/06 ,  G11B5/73 ,  G11B5/733 ,  G11B5/735 ,  G11B5/738 ,  H05K1/05 ,  B21C1/00

CPC分类号： G11B5/735 ,  C22C21/06 ,  G11B5/7315 ,  H05K1/053 ,  Y10T428/1259

摘要： An aluminum substrate for magnetic recording media such as magnetic disks, etc., is composed of an aluminum alloy plate containing 2 to 6% by weight magnesium and impurities in only limited amounts and having on the surface an anodic oxidation film with thickness more than 3 .mu.m formed by a chromic acid process. In the thus-anodized aluminum substrate, the occurrence of black spot defects is greatly reduced and the formation of cracks upon heating the substrate to high temperatures is prevented in spite of the thicker anodic oxidation film.

摘要翻译： 用于诸如磁盘等的磁记录介质的铝基板由仅含有限量的含有2至6重量％的镁和杂质的铝合金板组成，并且在表面上具有厚度大于3的阳极氧化膜 由铬酸过程形成的微米。 在这样阳极氧化的铝基板中，尽管阳极氧化膜较厚，但是防止了黑斑缺陷的发生，并且在将基板加热到高温时形成裂缝。

公开(公告)号：US20090303664A1

公开(公告)日：2009-12-10

申请号：US12093514

申请日：2006-11-15

申请人： Fusayoshi Endoh ,  Kentaro Nakaaki ,  Masashi Ozawa ,  Koichi Yoshida ,  Osamu Nakamura

发明人： Fusayoshi Endoh ,  Kentaro Nakaaki ,  Masashi Ozawa ,  Koichi Yoshida ,  Osamu Nakamura

IPC分类号： H01G9/025

CPC分类号： H01G9/045 ,  H01G9/008 ,  H01G9/055 ,  H01G9/145

摘要： An electrolytic capacitor employs a capacitor element wherein an anode foil having an anode internal terminal and a cathode foil having a cathode internal terminal are wound or laminated through a separator. The end of the anode foil faces the cathode foil through the separator and the surface area of the cathode internal terminal is provided with an enlargement treatment, whereby the small area portion of the cathode foil that faces with the anode foil is eliminated, improving the charge/discharge characteristics. Furthermore, in the electrolytic capacitor provided with the capacitor element wherein the anode foil having the anode internal terminal and the cathode foil having the cathode internal terminal are wound or laminated through the separator, the capacitor element being impregnated with an electrolyte, the cathode internal terminal includes an aluminum material, the surface of the cathode internal terminal is etched and iron concentration in the etching layer

摘要翻译： 电解电容器采用电容器元件，其中具有阳极内部端子的阳极箔和具有阴极内部端子的阴极箔通过隔板缠绕或层压。 阳极箔的端部通过隔膜面向阴极箔，并且阴极内部端子的表面积被提供放大处理，从而消除了与阳极箔面对的阴极箔的小面积部分，从而改善电荷 /放电特性。 此外，在设置有电容器元件的电解电容器中，其中具有阳极内部端子的阳极箔和具有阴极内部端子的阴极箔通过隔板卷绕或层压，电容器元件浸渍有电解质，阴极内部端子 包括铝材料，阴极内部端子的表面被蚀刻，并且蚀刻层中的铁浓度<300ppm。