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21.发明公开公开(公告)号：US20230418863A1
公开(公告)日：2023-12-28
申请号：US18244587
申请日：2023-09-11
Applicant: Protochips, Inc.
Inventor： Franklin Stampley Walden, II , John Damiano, JR. , David P. Nackashi , Daniel Stephen Gardiner , Mark Uebel , Alan Philip Franks , Joshua Friend , Katherine Elizabeth Marusak
IPC: G06F16/535 , G06T1/00 , G06T11/60 , G06T7/20 , G06F16/538 , G06F16/58 , G06F16/51
CPC classification number: G06F16/535 , G06T1/0007 , G06T11/60 , G06T7/20 , G06F16/538 , G06F16/5866 , G06F16/51 , G06T2207/10061 , G06T2200/24
Abstract: Disclosed herein are methods and systems of metadata management for reviewing data from microscopy experimental sessions. Image data from an experimental session is stored in an archive at one or more filepath locations, either locally or on a network. Metadata associated with the image data is stored in a database with a reference to the filepath where the raw image is stored, such that the metadata is associated in the database with the image data. A user can perform post-experimental filtering, sorting, and searching of the underlying image data using the metadata, which allows the image data to be analyzed without duplication of the image data and without manual review of each individual image. The filtered data is presented in an interactive timeline format.
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公开(公告)号：US20230049691A1
公开(公告)日：2023-02-16
申请号：US17931466
申请日：2022-09-12
Applicant: Protochips, Inc.
Inventor： Franklin Stampley Walden, II , John Damiano, JR. , David P. Nackashi , Daniel Stephen Gardiner , Mark Uebel , Alan Philip Franks , Joshua Friend , Katherine Elizabeth Marusak
IPC: G06F16/535 , G06T1/00 , G06T11/60 , G06T7/20 , G06F16/538 , G06F16/58 , G06F16/51
Abstract: Disclosed herein are methods and systems of metadata management for reviewing data from microscopy experimental sessions. Image data from an experimental session is stored in an archive at one or more filepath locations, either locally or on a network. Metadata associated with the image data is stored in a database with a reference to the filepath where the raw image is stored, such that the metadata is associated in the database with the image data. A user can perform post-experimental filtering, sorting, and searching of the underlying image data using the metadata, which allows the image data to be analyzed without duplication of the image data and without manual review of each individual image. The filtered data is presented in an interactive timeline format.
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公开(公告)号：US20220327156A1
公开(公告)日：2022-10-13
申请号：US17715831
申请日：2022-04-07
Applicant: Protochips, Inc.
Inventor： Franklin Stampley Walden, II , John Damiano, JR. , David P. Nackashi , Daniel Stephen Gardiner , Mark Uebel , Alan Philip Franks , Joshua Friend , Katherine Elizabeth Marusak
IPC: G06F16/535 , G06T1/00 , G06T11/60 , G06T7/20 , G06F16/51 , G06F16/538 , G06F16/58
Abstract: Disclosed herein are methods and systems of metadata management for reviewing data from microscopy experimental sessions. Image data from an experimental session is stored in an archive at one or more filepath locations, either locally or on a network. Metadata associated with the image data is stored in a database with a reference to the filepath where the raw image is stored, such that the metadata is associated in the database with the image data. A user can perform post-experimental filtering, sorting, and searching of the underlying image data using the metadata, which allows the image data to be analyzed without duplication of the image data and without manual review of each individual image. The filtered data is presented in an interactive timeline format.
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公开(公告)号：US11455333B1
公开(公告)日：2022-09-27
申请号：US17715831
申请日：2022-04-07
Applicant: Protochips, Inc.
Inventor： Franklin Stampley Walden, II , John Damiano, Jr. , David P. Nackashi , Daniel Stephen Gardiner , Mark Uebel , Alan Philip Franks , Joshua Friend , Katherine Elizabeth Marusak
IPC: G06K9/00 , G06F16/535 , G06T1/00 , G06T11/60 , G06T7/20 , G06F16/538 , G06F16/58 , G06F16/51
Abstract: Disclosed herein are methods and systems of metadata management for reviewing data from microscopy experimental sessions. Image data from an experimental session is stored in an archive at one or more filepath locations, either locally or on a network. Metadata associated with the image data is stored in a database with a reference to the filepath where the raw image is stored, such that the metadata is associated in the database with the image data. A user can perform post-experimental filtering, sorting, and searching of the underlying image data using the metadata, which allows the image data to be analyzed without duplication of the image data and without manual review of each individual image. The filtered data is presented in an interactive timeline format.
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公开(公告)号：US20210235021A1
公开(公告)日：2021-07-29
申请号：US17210702
申请日：2021-03-24
Applicant: Protochips, Inc.
Inventor： Franklin Stampley Walden, II , John Damiano, JR. , David P. Nackashi , Daniel Stephen Gardiner , Mark Uebel , Alan Philip Franks , Benjamin Jacobs
Abstract: Control system configured for sample tracking in an electron microscope environment registers a movement associated with a region of interest located within an active area of a sample under observation with an electron microscope. The registered movement includes at least one directional constituent. The region of interest is positioned within a field of view of the electron microscope. The control system directs an adjustment of the electron microscope control component to one or more of dynamically center and dynamically focus the view through the electron microscope of the region of interest. The adjustment comprises one or more of a magnitude element and a direction element.
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Patent Agency Ranking
26.发明申请公开(公告)号：US20200043697A1
公开(公告)日：2020-02-06
申请号：US16653162
申请日：2019-10-15
Applicant: Protochips, Inc.
Inventor： Franklin Stampley Walden, II , John Damiano, JR. , Daniel Stephen Gardiner , David P. Nackashi , William Bradford Carpenter
Abstract: A heating device having a heating element patterned into a robust MEMs substrate, wherein the heating element is electrically isolated from a fluid reservoir or bulk conductive sample, but close enough in proximity to an imagable window/area having the fluid or sample thereon, such that the sample is heated through conduction. The heating device can be used in a microscope sample holder, e.g., for SEM, TEM, STEM, X-ray synchrotron, scanning probe microscopy, and optical microscopy.
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27.发明授权公开(公告)号：US10373800B2
公开(公告)日：2019-08-06
申请号：US16004952
申请日：2018-06-11
Applicant: Protochips, Inc.
Abstract: A support for an electron microscope sample includes a body defining a void for receiving a first micro-electronic device, and a first gasket positioned about the first surface. The first gasket further defines an arm extending at an angle away from a horizontal extending through the first micro-electronic device. In operation, the first micro-electronic device is installed onto the first gasket and the arm engages an outer facing side of the first micro-electronic device to grip the first micro-electronic device.
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28.发明授权公开(公告)号：US09818578B2
公开(公告)日：2017-11-14
申请号：US14626234
申请日：2015-02-19
Applicant: PROTOCHIPS, INC.
Inventor： Daniel Stephen Gardiner , William Bradford Carpenter , John Damiano, Jr. , Franklin Stampley Walden, II , David P. Nackashi
CPC classification number: H01J37/261 , G01K11/32 , G01L11/025 , G01L19/04 , H01J37/16 , H01J37/20 , H01J37/3178 , H01J2237/2001 , H01J2237/2002 , H01J2237/2801
Abstract: An apparatus and a method for measuring and monitoring the properties of a fluid, for example, pressure, temperature, and chemical properties, within a sample holder for an electron microscope. The apparatus includes at least one fiber optic sensor used for measuring temperature and/or pressure and/or pH positioned in proximity of the sample.
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29.发明申请METHOD FOR OPTIMIZING FLUID FLOW ACROSS A SAMPLE WITHIN AN ELECTRON MICROSCOPE SAMPLE HOLDER 有权通过电子显微镜样品保持器中的样品优化流体流动的方法公开(公告)号：US20150348745A1
公开(公告)日：2015-12-03
申请号：US14729547
申请日：2015-06-03
Applicant: PROTOCHIPS, INC.
CPC classification number: H01J37/261 , B01L9/52 , B01L2200/0636 , F16J15/022 , F16J15/062 , F16J15/064 , F16J15/104 , H01J37/20 , H01J2237/2003 , H01J2237/2006 , H01J2237/2007
Abstract: A flow directing gasket for improving the flow of a gas or liquid across electron beam transparent membranes in environmental cells within a sample holder of an electron microscope, and uses of the sample holders comprising said flow directing gaskets.
Abstract translation: 用于改善气体或液体在电子显微镜的样品保持器内的环境细胞中的电子束透明膜的流动的流动引导衬垫，以及包括所述流动引导衬垫的样品保持器的用途。
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30.发明公开公开(公告)号：US20240267628A1
公开(公告)日：2024-08-08
申请号：US18437770
申请日：2024-02-09
Applicant: Protochips, Inc.
Inventor： Franklin Stampley Walden, II , John Damiano, JR. , David P. Nackashi , Daniel Stephen Gardiner , Mark Uebel , Alan Philip Franks , Benjamin Jacobs , Joshua Brian Friend , Katherine Elizabeth Marusak , Nelson L. Marthe, JR. , Benjamin Bradshaw Larson
IPC: H04N23/695 , G06T7/215 , G06T7/33 , H01J37/20
CPC classification number: H04N23/695 , G06T7/215 , G06T7/337 , H01J37/20 , G06T2207/10061 , H01J2237/2594
Abstract: Methods and systems for calibrating a transmission electron microscope are disclosed. A fiducial mark on the sample holder is used to identify known reference points so that a current collection area and a through-hole on the sample holder can be located. A plurality of beam current and beam area measurements are taken, and calibration tables are extrapolated from the measurements for a full range of microscope parameters. The calibration tables are then used to determine electron dose of a sample during an experiment at a given configuration.
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