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公开(公告)号：US08170659B2
公开(公告)日：2012-05-01
申请号：US12080787
申请日：2008-04-04
申请人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
发明人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC分类号： A61N1/18
CPC分类号： A61F7/00 , A61B5/4035 , A61B5/411 , A61F2007/0075 , A61N1/36021 , A61N1/36071 , A61N1/36535 , A61N1/36542 , A61N1/403 , A61N2/00 , A61N7/00 , A61N2005/0659
摘要： Methods and related systems for modulating neural activity by blocking conduction in peripheral neural structures with thermal stimuli are disclosed. Methods and systems for reversing effects of thermal blocking stimuli and/or for producing substantially permanent conduction block are also disclosed.
摘要翻译： 公开了通过用热刺激阻断外周神经结构传导来调节神经活动的方法和相关系统。 还公开了用于逆转热阻止刺激的作用和/或用于产生基本上永久的传导阻滞的方法和系统。
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22.发明授权公开(公告)号：US08630706B2
公开(公告)日：2014-01-14
申请号：US13385923
申请日：2012-03-13
申请人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
发明人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC分类号： A61N1/18
CPC分类号： A61M5/14276 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/1118 , A61B5/14539 , A61B5/4035 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4821 , A61B5/4839 , A61F7/00 , A61F7/0085 , A61F2007/0075 , A61M5/14244 , A61M5/14248 , A61M5/16827 , A61M5/1723 , A61M35/00 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/30 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36103 , A61N1/36135 , A61N1/37252 , A61N2/002 , A61N2/006 , A61N7/00 , A61N2007/0026
摘要： Methods and related systems for modulating neural activity by repetitively blocking conduction in peripheral neural structures with chemical blocking agents are disclosed. Methods and systems for reversing effects of chemical blocking agents and/or for producing substantially permanent conduction block are also disclosed.
摘要翻译： 公开了通过用化学阻断剂重复地阻断外周神经结构传导来调节神经活动的方法和相关系统。 还公开了用于逆转化学阻断剂的作用和/或用于产生基本上永久的传导阻滞的方法和系统。
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公开(公告)号：US08160695B2
公开(公告)日：2012-04-17
申请号：US12214533
申请日：2008-06-18
申请人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
发明人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC分类号： A61N1/18
CPC分类号： A61N1/36014 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/04001 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/14539 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4839 , A61F7/00 , A61M5/14244 , A61M5/14276 , A61M5/16827 , A61M5/1723 , A61M37/0015 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/3605 , A61N1/36189 , A61N1/36535 , A61N1/36542 , A61N1/37252 , A61N2/006 , A61N7/00
摘要： Methods and related systems for modulating neural activity by repetitively blocking conduction in peripheral neural structures with chemical blocking agents are disclosed. Methods and systems for reversing effects of chemical blocking agents and/or for producing substantially permanent conduction block are also disclosed.
摘要翻译： 公开了通过用化学阻断剂重复地阻断外周神经结构传导来调节神经活动的方法和相关系统。 还公开了用于逆转化学阻断剂的作用和/或用于产生基本上永久的传导阻滞的方法和系统。
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公开(公告)号：US08233976B2
公开(公告)日：2012-07-31
申请号：US12214557
申请日：2008-06-18
申请人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
发明人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC分类号： A61N1/18
CPC分类号： A61M5/14276 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/1118 , A61B5/14539 , A61B5/4035 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4821 , A61B5/4839 , A61F7/00 , A61F7/0085 , A61F2007/0075 , A61M5/14244 , A61M5/14248 , A61M5/16827 , A61M5/1723 , A61M35/00 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/30 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36103 , A61N1/36135 , A61N1/37252 , A61N2/002 , A61N2/006 , A61N7/00 , A61N2007/0026
摘要： Methods and related systems for modulating neural activity by repetitively blocking conduction in peripheral neural structures with chemical blocking agents are disclosed. Systems for transdermal delivery of chemical blocking agents are disclosed. Methods and systems for reversing effects of chemical blocking agents and/or for producing substantially permanent conduction block are also disclosed.
摘要翻译： 公开了通过用化学阻断剂重复地阻断外周神经结构传导来调节神经活动的方法和相关系统。 公开了用于透皮递送化学阻断剂的系统。 还公开了用于逆转化学阻断剂的作用和/或用于产生基本上永久的传导阻滞的方法和系统。
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公开(公告)号：US08195287B2
公开(公告)日：2012-06-05
申请号：US12070361
申请日：2008-02-15
申请人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
发明人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC分类号： A61N1/18
CPC分类号： A61N1/3605 , A61N1/0556 , A61N1/321 , A61N1/36014 , A61N1/36017 , A61N1/36071 , A61N1/36189 , A61N1/36535 , A61N1/36542 , A61N2/006
摘要： Methods and related systems for modulating neural activity by repetitively blocking conduction in peripheral neural structures with electrical stimuli are disclosed. Methods and systems for reversing effects of blocking stimuli and/or for producing substantially permanent conduction block are also disclosed.
摘要翻译： 公开了通过用电刺激重复地阻断外周神经结构传导来调节神经活动的方法和相关系统。 还公开了用于逆转阻断刺激的作用和/或用于产生基本上永久的传导阻滞的方法和系统。
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公开(公告)号：US08165669B2
公开(公告)日：2012-04-24
申请号：US12070369
申请日：2008-02-15
申请人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
发明人： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC分类号： A61N1/18
CPC分类号： A61N2/006 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/04001 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/14539 , A61B5/14546 , A61B5/4041 , A61B5/411 , A61B5/441 , A61N2/02
摘要： Methods and related systems for modulating neural activity by repetitively blocking conduction in peripheral neural structures with magnetic stimuli are disclosed. Methods and systems for reversing effects of blocking stimuli and/or for producing substantially permanent conduction block are also disclosed.
摘要翻译： 公开了通过用磁刺激重复地阻断外周神经结构传导来调节神经活动的方法和相关系统。 还公开了用于逆转阻断刺激的作用和/或用于产生基本上永久的传导阻滞的方法和系统。
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27.发明申请System, devices, and methods including actively-controllable sterilizing excitation delivery implants 有权系统，装置和方法，包括主动控制的消毒激励输送植入物公开(公告)号：US20100174346A1
公开(公告)日：2010-07-08
申请号：US12592976
申请日：2009-12-03
申请人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61F7/00
CPC分类号： A61F2/02 , A61F2/30 , A61F2002/009 , A61F2002/30087 , A61F2002/3067 , A61F2002/30677 , A61F2002/3068 , A61F2002/3084 , A61F2002/30932 , A61F2002/481 , A61F2002/482 , A61F2250/0002 , A61F2250/0068 , A61F2310/00616 , A61L2/0011 , A61L2/0023 , A61L2/0029 , A61L2/0088 , A61L2/025 , A61L2/03 , A61N1/205 , A61N1/36 , A61N1/37252 , A61N1/3785 , A61N1/3787
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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28.发明申请公开(公告)号：US20100145412A1
公开(公告)日：2010-06-10
申请号：US12380553
申请日：2009-02-27
申请人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61N1/08
CPC分类号： A61F2/30 , A61F2/32 , A61F2002/30087 , A61F2002/3067 , A61F2002/30677 , A61F2002/48 , A61F2002/481 , A61F2002/482 , A61F2250/0002 , A61F2310/0097 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2202/14 , A61L2202/24 , A61M5/001 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
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29.发明申请System, devices, and methods including sterilizing excitation delivery implants with cryptographic logic components 审中-公开系统，设备和方法，包括消毒具有加密逻辑组件的激励传递植入物公开(公告)号：US20090163977A1
公开(公告)日：2009-06-25
申请号：US12315881
申请日：2008-12-04
申请人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61N1/36
CPC分类号： A61L2/0011 , A61L2/08
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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30.发明申请System, devices, and methods including sterilizing excitation delivery implants with general controllers and onboard power 审中-公开系统，设备和方法，包括消除具有通用控制器和车载电源的激励输送种植体公开(公告)号：US20090163964A1
公开(公告)日：2009-06-25
申请号：US12315882
申请日：2008-12-04
申请人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： A61L2/0011 , A61L2/0023 , A61L2/0052
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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