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    Novel substance having alpha-glucosidase inhibiting activity and food containing the same
    21.
    发明申请
    Novel substance having alpha-glucosidase inhibiting activity and food containing the same 审中-公开
    具有α-葡糖苷酶抑制活性的新物质和含有其的食品

    公开(公告)号：US20070037870A1

    公开(公告)日：2007-02-15

    申请号：US10553943

    申请日：2004-04-23

    申请人： Masanori Asada ,  Yuzo Kawahara ,  Shinichi Kitamura

    发明人： Masanori Asada ,  Yuzo Kawahara ,  Shinichi Kitamura

    IPC分类号： A61K31/381 ,  C07D333/32

    CPC分类号： C07D333/46 ,  A23L33/10

    摘要： To provide a novel substance having α-glucosidase inhibiting activity, derived from natural products and being safe, which substance has not only a blood sugar ameliorating activity being effective in the prevention or treatment of diabetes or obesity but also an activity of reducing postprandial hyper-blood sugar, etc. and to provide food containing the same. [MEANS FOR SOLVING PROBLEMS] A substance having α-glucosidase inhibiting activity, represented by the formula:

    摘要翻译： 为了提供从天然产物得到并具有安全性的具有α-葡糖苷酶抑制活性的新型物质，该物质不仅具有有效预防或治疗糖尿病或肥胖症的血糖改善活性，而且还降低餐后高血糖的活性， 血糖等，并提供含有相同的食物。 解决问题的手段具有α-葡糖苷酶抑制活性的物质由下式表示：

    Magnetic force microscope
    22.
    发明授权
    Magnetic force microscope 失效

    公开(公告)号：US06504365B2

    公开(公告)日：2003-01-07

    申请号：US09966342

    申请日：2001-09-27

    申请人： Shinichi Kitamura

    发明人： Shinichi Kitamura

    IPC分类号： G01R3302

    CPC分类号： G01R33/0385 ,  G01Q30/16 ,  G01Q60/08 ,  Y10S977/865

    摘要： A magnetic force microscope capable of producing a topographic image containing no magnetic information. In the topographic imaging mode, an error amplifier controls the distance between a cantilever and the sample to cause the oscillation frequency of the cantilever to shift from f0 to f1, for causing a probe to tap each observation position (xi, yj) on the sample. According to the results of the control, topographic information in the observation position (xi, yj) is obtained. In the magnetic force imaging mode, the probe is placed on the observation position (xi, yj), and the distance between the cantilever and the sample is held to the distance used in the topographic imaging mode according to information stored in the memory. At this time, the amplitude of the cantilever is so adjusted that the probe does not tap the sample. Magnetic information about the observation position (xi, yj) on the sample is obtained based on the oscillation frequency of the cantilever at this time.

    Scanning microscope for image topography and surface potential
    24.
    发明授权
    Scanning microscope for image topography and surface potential 失效
    扫描显微镜用于图像形貌和表面电位

    公开(公告)号：US06073485A

    公开(公告)日：2000-06-13

    申请号：US113956

    申请日：1998-07-10

    申请人： Shinichi Kitamura

    发明人： Shinichi Kitamura

    IPC分类号： G01N37/00 ,  G01B7/34 ,  G01N27/00 ,  G01N27/22 ,  G01Q20/04 ,  G01Q30/04 ,  G01Q30/06 ,  G01Q60/24 ,  G01Q60/30 ,  G01Q60/32

    CPC分类号： G01Q60/30 ,  B82Y35/00 ,  Y10S977/849 ,  Y10S977/852 ,  Y10S977/86 ,  Y10S977/868 ,  Y10S977/871 ,  Y10S977/873

    摘要： There is disclosed a scanning probe microscope capable of producing a topographic image at a high resolution with a cantilever of a large spring constant and, at the same time, a surface potential image at a high resolution. This microscope can take the form of an atomic force microscope that detects the surface potential of a sample, using a gradient of the force acting between the probe tip and a sample. The gradient is represented by the output from a frequency-to-voltage converter. The frequency of an AC voltage applied across the probe tip and the sample is so set that a z-signal fed back to the cantilever to maintain constant the shift in the resonance frequency of the cantilever can sufficiently follow the AC voltage.

    摘要翻译： 公开了一种扫描探针显微镜，能够以大的弹簧常数的悬臂以高分辨率产生地形图像，同时以高分辨率产生表面电位图像。 该显微镜可以采用原子力显微镜的形式，其使用在探针尖端和样品之间作用的力的梯度来检测样品的表面电位。 梯度由频率 - 电压转换器的输出表示。 跨越探针尖端和样品施加的AC电压的频率被设定为使得反馈到悬臂的z信号保持恒定，所述悬臂的谐振频率的偏移可以充分地跟随AC电压。

    Scanning probe microscope
    25.
    发明授权
    Scanning probe microscope 失效
    扫描探针显微镜提供地形图像和磁图像

    公开(公告)号：US5939715A

    公开(公告)日：1999-08-17

    申请号：US31641

    申请日：1997-02-27

    申请人： Shinichi Kitamura ,  Takashi Sueyoshi

    发明人： Shinichi Kitamura ,  Takashi Sueyoshi

    IPC分类号： G01B21/30 ,  G01B7/00 ,  G01B7/34 ,  G01N37/00 ,  G01Q30/04 ,  G01Q60/00 ,  G01Q60/08 ,  G01Q60/24 ,  G01Q60/32 ,  G01Q60/50 ,  G01Q60/56 ,  G01R33/038 ,  H01J3/14

    CPC分类号： G01Q60/08 ,  B82Y35/00 ,  G01B7/00 ,  G01Q60/32 ,  G01Q60/52 ,  G01R33/0385 ,  B82Y25/00 ,  Y10S977/865

    摘要： There is disclosed a scanning probe microscope capable of producing a topographic image and a magnetic image of a surface of a sample in one measurement. The microscope has a probe tip made of a magnetic material. A physical force, such as an atomic force, is exerted between the probe tip and the sample. When this physical force does not act on the probe tip, it vibrates at a first vibrational frequency. Displacements of the probe tip are detected by a photodetector. A topographic information-extracting portion including a voltage-to-current converter, a phase shifter, an FM demodulator, a low-pass filter, and an error amplifier extracts a signal representative of topographic information from the output from the photodetector. A magnetic distribution-extracting portion, including an oscillator and a lock-in amplifier, extracts information about the magnetism of the sample from the output from the photodetector.

    摘要翻译： 公开了一种能够在一次测量中产生样品表面的地形图像和磁性图像的扫描探针显微镜。 显微镜具有由磁性材料制成的探针尖端。 在探针尖端和样品之间施加诸如原子力的物理力。 当该物理力不作用于探针尖端时，其以第一振动频率振动。 探针尖端的位移由光检测器检测。 包括电压 - 电流转换器，移相器，FM解调器，低通滤波器和误差放大器的地形信息提取部分从光电检测器的输出中提取表示地形信息的信号。 包括振荡器和锁定放大器的磁分布提取部分从光电检测器的输出中提取关于样品的磁性的信息。

    Scanning tunneling microscope
    26.
    发明授权
    Scanning tunneling microscope 失效
    扫描隧道显微镜

    公开(公告)号：US5438196A

    公开(公告)日：1995-08-01

    申请号：US163339

    申请日：1993-12-06

    申请人： Shinichi Kitamura

    发明人： Shinichi Kitamura

    IPC分类号： G01B7/34 ,  G01Q30/02 ,  G01Q60/10 ,  H01J37/252 ,  H01J37/28

    CPC分类号： G01Q60/16 ,  B82Y35/00 ,  G01Q10/04 ,  G01Q30/02 ,  H01J2237/0807 ,  Y10S977/861

    摘要： A scanning tunneling microscope having a scanner driven in three dimensions. A conducting tip is attached to the front end of the scanner. A voltage is applied between the tip and a specimen. Movement of the tip is controlled so that the resulting tunneling current is maintained constant. A scanning tunneling microscope (STM) image is created from a control signal for controlling the movement of the tip. The microscope is equipped with a secondary electron detector for detecting secondary electrons emitted from the specimen when the voltage applied between the tip and the specimen is increased. A secondary electron image originating from the same field of view as the STM image is derived.

    摘要翻译： 扫描隧道显微镜，具有三维驱动的扫描仪。 导电尖端连接到扫描仪的前端。 在尖端和样品之间施加电压。 控制尖端的移动，使得所得到的隧道电流保持恒定。 扫描隧道显微镜（STM）图像由用于控制尖端运动的控制信号产生。 显微镜配备有二次电子检测器，用于当尖端和样本之间施加的电压增加时，检测从样品发射的二次电子。 导出与STM图像相同视场的二次电子图像。

    ANTI-ALLERGIC AGENT
    28.
    发明申请
    ANTI-ALLERGIC AGENT 审中-公开
    抗过敏剂

    公开(公告)号：US20130005959A1

    公开(公告)日：2013-01-03

    申请号：US13634336

    申请日：2011-03-22

    申请人： Mamiko Kohno ,  Shinichi Kitamura ,  Aiko Shojo

    发明人： Mamiko Kohno ,  Shinichi Kitamura ,  Aiko Shojo

    IPC分类号： C08B37/00 ,  C12N1/20

    CPC分类号： A61K35/745 ,  A61K31/715 ,  A61K31/716 ,  C08B37/006 ,  A61K2300/00

    摘要： According to the present invention, an anti-allergic agent is provided which includes a polysaccharide comprising galactose, glucose and rhamnose as constituents, or includes a microorganism belonging to a genus Bifidobacterium and extracellularly producing the polysaccharide. The anti-allergic agent of the present invention can be used in oral compositions and compositions for external application, and is suitable for use in products such as food products, pharmaceutical products, and cosmetics.

    摘要翻译： 根据本发明，提供了包含含有半乳糖，葡萄糖和鼠李糖作为成分的多糖的抗过敏剂，或者包括属于双歧杆菌属的微生物，并且在细胞外产生多糖。 本发明的抗过敏剂可以用于外用的口腔用组合物和组合物中，适用于食品，药品，化妆品等产品。

    Phase feedback AFM and control method therefor
    29.
    发明授权
    Phase feedback AFM and control method therefor 失效
    相位反馈AFM及其控制方法

    公开(公告)号：US07836757B2

    公开(公告)日：2010-11-23

    申请号：US12051362

    申请日：2008-03-19

    申请人： Shinichi Kitamura

    发明人： Shinichi Kitamura

    IPC分类号： G01B5/28 ,  G01Q30/06 ,  G01Q60/24

    CPC分类号： G01Q60/32 ,  G01Q10/065

    摘要： A phase feedback AFM (atomic force microscope) and method for the phase feedback AFM. A cantilever is driven to oscillate at a constant frequency close to the resonance frequency of the cantilever by a driving signal. The distance between the probe and the sample is controlled such that the phase difference between the driving signal and a cantilever deflection signal indicating deflections of the cantilever is kept constant. The phase feedback AFM has an amplifier-controller for receiving the cantilever deflection signal, the output from an oscillator for driving the cantilever into oscillation, and a signal representing a reference amplitude of oscillation of the cantilever. The phase feedback AFM further includes a feedback circuit which receives the output from the amplifier-controller which controls the cantilever deflection signal to a preset amplitude.

    摘要翻译： 相位反馈AFM（原子力显微镜）和相位反馈AFM的方法。 通过驱动信号驱动悬臂以接近悬臂的共振频率的恒定频率振荡。 控制探针和样品之间的距离，使得驱动信号和指示悬臂的偏转的悬臂偏转信号之间的相位差保持恒定。 相位反馈AFM具有用于接收悬臂偏转信号的放大器控制器，用于驱动悬臂振荡的振荡器的输出以及表示悬臂的基准振荡振幅的信号。 相位反馈AFM还包括反馈电路，其接收来自控制悬臂偏转信号到预设幅度的放大器控制器的输出。

    SECONDARY CELL DEGRADATION STATE JUDGMENT SYSTEM
    30.
    发明申请
    SECONDARY CELL DEGRADATION STATE JUDGMENT SYSTEM 有权
    二级细胞降解状态判定系统

    公开(公告)号：US20100256935A1

    公开(公告)日：2010-10-07

    申请号：US12744398

    申请日：2008-11-26

    申请人： Tsurayoshi Imanishi ,  Shinichi Kitamura

    发明人： Tsurayoshi Imanishi ,  Shinichi Kitamura

    IPC分类号： G01R31/36 ,  G06F19/00

    CPC分类号： G01R31/3679 ,  G01R31/3682

    摘要： A secondary cell degradation state judgment system which includes: operation information measurement means (5) measuring operations information on a secondary cell (3) such as a temperature, an elapse time, a discharge depth, and a discharge capacitance of the secondary cell; degradation value calculation means (7) which calculates degradation values (15) respectively corresponding to the measurement values according to the measurement values; degradation accumulation value storage means (8) which stores degradation accumulation values (14) accumulated for each of the calculated degradation values; main accumulation value selection means (9) which selects the greatest degradation value as a main accumulation value (16) from the degradation accumulation values; and overall degradation value calculation means (10) which calculates an overall degradation value (18) according to the selected main accumulation value and a degradation value corresponding to the degradation accumulation values which have not been selected as the main accumulation value.

    摘要翻译： 二次电池劣化状态判断系统，包括：操作信息测量装置（5），测量二次电池的温度，经过时间，放电深度和放电电容等二次电池（3）的操作信息; 劣化值计算装置（7），其根据测量值分别对应于测量值计算劣化值（15）; 劣化累积值存储装置（8），其存储针对每个所计算的劣化值累积的劣化累积值（14） 主累积值选择装置（9），其根据劣化累积值选择最大劣化值作为主累积值（16）; 和整体劣化值计算装置（10），其根据所选择的主累积值和对应于未被选择为主累积值的劣化累积值的劣化值来计算总体劣化值（18）。