公开(公告)号：US20240299733A1

公开(公告)日：2024-09-12

申请号：US18654336

申请日：2024-05-03

申请人： MAGENTA MEDICAL LTD

发明人： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC分类号： A61M60/90 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

CPC分类号： A61M60/90 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865 ,  A61M2205/0266 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/3303 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/3365 ,  A61M2205/502 ,  A61M2207/10 ,  A61M2230/30

摘要： Apparatus and methods are described including an axial shaft and an impeller configured for rotation within a subject's body. A coupling element includes a first portion, which is disposed around the axial shaft, is shaped to define one or more slits that facilitate a radial expansion of the first portion such that the first portion is placeable around the axial shaft, and is shape-set to have an inner diameter that is smaller than a diameter of the axial shaft such that, following placement of the first portion around the axial shaft, the first portion becomes radially contracted around, and thus locked in place with respect to, the axial shaft. A second portion of the coupling element is coupled to a bushing of the impeller. Other applications are also described.

公开(公告)号：US20240277996A1

公开(公告)日：2024-08-22

申请号：US18652956

申请日：2024-05-02

申请人： Magenta Medical Ltd

发明人： Yosi Tuval ,  Gad Lubinsky ,  Victor Troshin ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC分类号： A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

CPC分类号： A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

摘要： Apparatus and methods are described including a ventricular assist device that includes an axial shaft and an impeller disposed on the axial shaft, the impeller being configured to pump blood. A frame is disposed around the impeller. A distal thrust bearing is disposed within the frame, the distal end of the axial shaft being configured to engage with the distal thrust bearing such as to prevent the axial shaft from undergoing axial motion in response to variations in the pressure gradient against which the impeller pumps blood. A plurality of connecting struts extend radially inwardly from the frame to the distal thrust bearing and couple the thrust bearing to the frame. The frame and the connecting struts are formed as a single integral body. Other applications are also described.

公开(公告)号：US20240277995A1

公开(公告)日：2024-08-22

申请号：US18652930

申请日：2024-05-02

申请人： Magenta Medical Ltd

发明人： Yosi Tuval ,  Gad Lubinsky ,  Victor Troshin ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC分类号： A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

CPC分类号： A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

摘要： Apparatus and methods are described including packaging for a ventricular assist device. The packaging defines a pump-head chamber in which the pump head is packaged in a non-radially constrained configuration. A catheter-securement piece is shaped to define a hole and is configured to secure a distal end of the delivery catheter to the packaging by securing the delivery catheter within the hole. The packaging is configured such that the pump head is configured to be radially constrained by being retracted into the distal end of the delivery catheter, while the delivery catheter is secured within the hole. Other applications are also described.

公开(公告)号：US20240277993A1

公开(公告)日：2024-08-22

申请号：US18639079

申请日：2024-04-18

申请人： MAGENTA MEDICAL LTD

发明人： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC分类号： A61M60/237 ,  A61M60/174 ,  A61M60/414 ,  A61M60/419 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829

CPC分类号： A61M60/237 ,  A61M60/174 ,  A61M60/414 ,  A61M60/419 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829

摘要： Apparatus and methods are described including an axial shaft configured for insertion into, and rotation within, a ventricle of a heart of a subject. An impeller is coupled to the axial shaft and a frame surrounds the impeller. A pump-outlet tube surrounds the frame such that, as the axial shaft rotates, the impeller pumps blood proximally, from the ventricle, through the pump-outlet tube. A flat inlet guard, which is shaped to define one or more holes, is disposed around, and perpendicular to, the axial shaft and within the frame distally to the impeller, such that the blood flows to the impeller via the holes. Other applications are also described.

公开(公告)号：US20240277992A1

公开(公告)日：2024-08-22

申请号：US18640303

申请日：2024-04-19

申请人： MAGENTA MEDICAL LTD

发明人： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC分类号： A61M60/216 ,  A61M60/13 ,  A61M60/178 ,  A61M60/408 ,  A61M60/508 ,  A61M60/818

CPC分类号： A61M60/216 ,  A61M60/13 ,  A61M60/178 ,  A61M60/408 ,  A61M60/508 ,  A61M60/818

摘要： Apparatus and methods are described including a left-ventricular assist device, that includes a collapsible pump-outlet tube configured for insertion, through an aorta of a subject, into a left ventricle of a heart of the subject such that the pump-outlet tube traverses an aortic valve of the subject. The device includes one or more bands, each of which is bonded to an outer wall of the proximal portion of the pump-outlet tube, without extending around a full circumference of the pump-outlet tube, such that, while the proximal portion of the pump-outlet tube is maintained in the open state, the proximal portion of the pump-outlet tube curves at respective locations of the bands. Other applications are also described.

公开(公告)号：US20240252812A1

公开(公告)日：2024-08-01

申请号：US18632533

申请日：2024-04-11

申请人： MAGENTA MEDICAL LTD

发明人： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC分类号： A61M60/90 ,  A61M60/13 ,  A61M60/178 ,  A61M60/237 ,  A61M60/414 ,  A61M60/806 ,  A61M60/81 ,  A61M60/818 ,  A61M60/833

CPC分类号： A61M60/90 ,  A61M60/13 ,  A61M60/178 ,  A61M60/237 ,  A61M60/414 ,  A61M60/806 ,  A61M60/81 ,  A61M60/818 ,  A61M60/833 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2210/125 ,  A61M2210/127

摘要： Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more blood-outlet openings and configured for insertion into a subject's left ventricle, such that the blood-outlet openings are disposed within the subject's aorta and a distal portion of the pump-outlet tube is disposed within the left ventricle. An impeller is disposed within the pump-outlet tube and is configured to pump blood of the subject proximally through the pump-outlet tube. A delivery tube extends from outside the subject's body to the distal portion of the pump-outlet tube. An expandable element surrounds the delivery tube proximally to the blood-outlet openings, a length of the delivery tube between the expandable element and the blood-outlet openings being less than 30 mm. Other applications are also described.

公开(公告)号：US20240225814A1

公开(公告)日：2024-07-11

申请号：US18510983

申请日：2023-11-16

申请人： Magenta Medical Ltd

发明人： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman

IPC分类号： A61F2/07 ,  A61B5/0205 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/33 ,  A61M60/411 ,  A61M60/422 ,  A61M60/523 ,  A61M60/808 ,  A61M60/81 ,  A61M60/825 ,  A61M60/833 ,  A61M60/861 ,  A61M60/148 ,  A61M60/414 ,  A61M60/896

CPC分类号： A61F2/07 ,  A61B5/02055 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/33 ,  A61M60/411 ,  A61M60/422 ,  A61M60/523 ,  A61M60/808 ,  A61M60/81 ,  A61M60/825 ,  A61M60/833 ,  A61M60/861 ,  A61M60/148 ,  A61M60/414 ,  A61M60/896 ,  A61M2207/00 ,  A61M2210/1082 ,  A61M2210/12

摘要： Apparatus and methods are described including an impeller configured, in a radially-expanded configuration thereof, to pump a fluid by rotating. A radially expandable cage is disposed around the impeller, such that, in radially-expanded configurations of the impeller and the cage, the impeller is separated from an inner surface of the cage. The impeller is disposed within the cage such that, in response to the cage becoming radially contracted and axially elongated, the impeller radially contracts and axially elongates. Other applications are also described.

公开(公告)号：US12023476B2

公开(公告)日：2024-07-02

申请号：US17173944

申请日：2021-02-11

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804

CPC分类号： A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

摘要： Apparatus and methods are described including a blood pump configured to be placed inside a body of subject. The blood pump includes an impeller, a frame disposed around the impeller, and a distal-tip portion disposed distally with respect to the frame. A duckbill valve is disposed entirely within a distal most 10 mm of the distal-tip portion. The duckbill valve defines a wide inlet and a narrow tip that defines a slit therethrough. The duckbill valve is proximally facing, such that the wide inlet faces a distal end of the distal-tip portion and such that the narrow tip faces away from the distal end of distal-tip portion. Other applications are also described.

公开(公告)号：US11944800B2

公开(公告)日：2024-04-02

申请号：US17177296

申请日：2021-02-17

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804

CPC分类号： A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

摘要： Apparatus and methods are described including a blood pump configured to be placed inside a body of subject, the blood pump including an impeller configured to pump the subject's blood by rotating, and an axial shaft upon which the impeller is disposed. Proximal and distal radial bearings are configured to stabilize the axial shaft radially during rotation of the impeller. An atraumatic distal-tip portion is disposed distally with respect to the impeller, the atraumatic distal-tip portion including an inflatable portion. A purging fluid is pumped toward the distal-tip portion, such as to (a) purge the distal bearing, and (b) inflate the inflatable portion of the distal-tip portion. Other applications are also described.

公开(公告)号：US11839540B2

公开(公告)日：2023-12-12

申请号：US17487145

申请日：2021-09-28

申请人： MAGENTA MEDICAL LTD.

发明人： Yosi Tuval

IPC分类号： A61F2/82 ,  A61F2/06 ,  A61F2/24 ,  A61F2/856 ,  A61F2/91 ,  A61F2/966 ,  A61F2/848

CPC分类号： A61F2/2418 ,  A61F2/82 ,  A61F2/856 ,  A61F2/2436 ,  A61F2/91 ,  A61F2/966 ,  A61F2002/068 ,  A61F2002/821 ,  A61F2002/8483 ,  A61F2002/8486 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/006

摘要： Apparatus and methods are described including identifying a subject as suffering from a condition that causes the subject to have elevated central venous pressure. In response thereto, a device is placed inside the subject's vena cava, and the device is deployed inside the subject's vena cava, such that, in a passive manner, the device reduces blood pressure within the subject's renal veins relative to the subject's central venous pressure. Other applications are also described.