公开(公告)号：US11921109B2

公开(公告)日：2024-03-05

申请号：US16543512

申请日：2019-08-16

申请人： Northeastern University ,  The General Hospital Corporation

发明人： Tania Konry ,  Martin L. Yarmush

IPC分类号： B01L3/00 ,  B01F25/433 ,  B01F33/30 ,  G01N21/64 ,  G01N33/53 ,  G01N33/543

CPC分类号： G01N33/54313 ,  B01F25/4331 ,  B01F33/30 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/502776 ,  G01N21/6428 ,  G01N33/5304 ,  G01N33/54366 ,  B01L2200/0605 ,  B01L2200/0647 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0883 ,  B01L2400/0487 ,  G01N2021/6439 ,  G01N2201/061

摘要： Microfluidic devices for use with reagents bound to microspheres for determination of the concentration of an analyte in a liquid sample are provided. The devices include two sequential mixing channels that promote rapid binding of microsphere-bound reagents with reagents in solution and a means for detecting labeled microsphere-bound reaction products. Also provided are methods for using the devices with microsphere-bound reagents to determine the concentration of an analyte in a liquid sample and to measure the binding affinity of antibody for an antigen.

公开(公告)号：US20240063665A1

公开(公告)日：2024-02-22

申请号：US17766325

申请日：2020-10-02

申请人： Northeastern University

发明人： Kaushik CHOWDHURY ,  Yousof NADERI

IPC分类号： H02J50/90 ,  H02J50/10 ,  H02J50/40

CPC分类号： H02J50/90 ,  H02J50/10 ,  H02J50/402

摘要： Sensing and charging of electronic devices using coils. A software-defined collaborative sensing approach can allow detection and location of multiple electronic devices with respect to a charging surface to allow for wireless charging thereof. Systems and methods can measure the interaction of devices with a generated magnetic field through a network of nested sensing coils that can sense the location of devices located around the network of coils based on their interaction with magnetic fields. Once the location of a device to be charged is determined, charging energy can be directed to the device based on its location on the charging surface. The charging surface can include one or more sensing nodes having a combination of nested active, or driven, and passive coils. These coils can be configured to transform existing two-dimensional (2D) surfaces or three-dimensional (3D) areas into a multi -device contactless wireless charger.

公开(公告)号：US20240052572A1

公开(公告)日：2024-02-15

申请号：US18269192

申请日：2021-12-20

申请人： Northeastern University

发明人： Yi Zheng ,  Yanpei Tian ,  Xiaojie Liu

IPC分类号： D21H17/11 ,  D21H21/28 ,  D21H27/00

CPC分类号： D21H17/11 ,  D21H21/28 ,  D21H27/00

摘要： Disclosed are composite paper materials comprising hydrophobic fluorocarbons. Also disclosed are passive cooling materials comprising the composite paper materials. Further disclosed are methods of making the composite paper materials.

公开(公告)号：US20240044740A1

公开(公告)日：2024-02-08

申请号：US18547754

申请日：2022-11-25

申请人： Northeastern University

发明人： Benguo HE ,  Xiating FENG ,  Jie WANG ,  Shichen QIU ,  Xiangrui MENG ,  Lei WANG

IPC分类号： G01M7/08 ,  G01N3/313 ,  G01N33/24

CPC分类号： G01M7/08 ,  G01N3/313 ,  G01N33/24

摘要： The invention provides a method and system for a blast-induced vibration monitoring of a tunnel in high asymmetric in-situ stresses. According to the method, triaxial vibration sensors are respectively fixed in areas having different radial depths inside surrounding rocks of a stress concentration area behind a tunnel face of the tunnel in high asymmetric in-situ stresses, and each triaxial vibration sensor monitors blast vibration velocity and acceleration at a position thereof. The system comprises a plurality of triaxial vibration sensors which are fixed in areas having different radial depths inside surrounding rocks of a stress concentration area behind a tunnel face of the tunnel in high asymmetric in-situ stresses, and each triaxial vibration sensor is used for monitoring blast vibration velocity and acceleration at a position thereof. The method and system can improve the safety and the efficiency of tunnel excavation construction.

公开(公告)号：US20240039504A1

公开(公告)日：2024-02-01

申请号：US18378254

申请日：2023-10-10

申请人： Northeastern University

发明人： Cristian CASSELLA ,  Xuanyi ZHAO

IPC分类号： H03H9/02 ,  H03H3/04 ,  H03H9/17 ,  H03H9/56 ,  H03H9/13

CPC分类号： H03H9/02031 ,  H03H3/04 ,  H03H9/176 ,  H03H9/568 ,  H03H9/13 ,  H03H2003/0435

摘要： A microelectromechanical resonator device is provided having two-dimensional resonant rods. The resonator device has a piezoelectric layer formed with a plurality of alternating rods and trenches. A bottom electrode is in contact with a bottom surface of the piezoelectric layer. A top electrode metal grating of conductive strips is aligned in contact with corresponding rods of the piezoelectric layer.

公开(公告)号：US20240029000A1

公开(公告)日：2024-01-25

申请号：US17912807

申请日：2021-12-03

申请人： Northeastern University

发明人： Hongrui GAO ,  Feng XUE ,  Yingwei ZHANG ,  Lin FENG ,  Shengyang ZHANG ,  Zubian LI

IPC分类号： G06Q10/0637

CPC分类号： G06Q10/06375

摘要： A second type computer assembly line balancing optimization method based on a migration genetic algorithm, and related to the technical field of assembly line balancing. The method uses assembly experience of similar assembly lines, the feasible solution set of the known assembly lines is transferred to the initial solution set of the assembly line balancing problem to be optimized, due to the migration of high-quality feasible solutions. The method can effectively reduce the sensitivity of the algorithm performance to the initial value and parameters, and improve the lower limit of the local optimal feasible solution of the heuristic algorithm to solve the assembly line balancing problem.

公开(公告)号：US20240011881A1

公开(公告)日：2024-01-11

申请号：US18219978

申请日：2023-07-10

申请人： Northeastern University

发明人： Hongwei Sun ,  Ilia Chiniforooshan Esfahani

IPC分类号： G01N11/16 ,  G01N29/036 ,  G01N29/22

CPC分类号： G01N11/16 ,  G01N29/036 ,  G01N29/222 ,  G01N2011/0073

摘要： A micropillar-enabled acoustic wave (μPAW) viscometer including a quartz crystal microbalance (QCM) substrate; at least one micropillar having a first end and a second end, defining a height therebetween, the at least one micropillar disposed on to the QCM substrate at the first end and extending perpendicular to the QCM substrate; and a film disposed between the at least one micropillar and the QCM substrate.

公开(公告)号：US11866779B2

公开(公告)日：2024-01-09

申请号：US16961074

申请日：2019-02-28

申请人： Northeastern University

发明人： Roger W. Giese ,  Poguang Wang

IPC分类号： C12Q1/68 ,  C12Q1/6872

CPC分类号： C12Q1/6872 ,  C12Q2523/313

摘要： MALDI-MS operated slightly under matrix storm conditions with a high-energy-transfer, acidic matrix, or these conditions with a high sample to matrix ratio, can with ultrasensitivity detect a nucleobase, modified or canonical, of a nucleic acid species as a jettisoned, protonated molecule.

公开(公告)号：US11859173B2

公开(公告)日：2024-01-02

申请号：US17366757

申请日：2021-07-02

申请人： Northeastern University ,  President and Fellows of Harvard College

发明人： Avinash M. Basavanna ,  Anna Duraj-Thatte ,  Neel S. Joshi

IPC分类号： C12N1/20 ,  C12N1/18 ,  C12R1/19

CPC分类号： C12N1/20 ,  C12N1/18 ,  C12R2001/19

摘要： Disclosed are biomaterials, including engineered living materials (ELMs), comprising a plurality of microbial cells, wherein the material has a Young's Modulus of at least 5 Gpa; and methods of fabricating said biomaterials.

公开(公告)号：US20230400500A1

公开(公告)日：2023-12-14

申请号：US18136612

申请日：2023-04-19

申请人： MERSEN USA EP Corp. ,  Northeastern University

发明人： Roy A. Ball ,  Jonathan C. Kim ,  Bradley M. Lehman

IPC分类号： G01R31/12 ,  H02S50/00

CPC分类号： G01R31/12 ,  H02S50/00

摘要： A series PV arc fault detection method and apparatus demodulates a current signal provided by a DC power source to an inverter to eliminate a DC component and periodic noise. Autocorrelation coefficients are generated from the demodulated current signal to monitor noise energy and variation and, based on the noise energy, a determination is made if an arc fault has occurred.