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公开(公告)号：US20170197207A1
公开(公告)日：2017-07-13
申请号：US15472327
申请日：2017-03-29
Applicant: Dale Lee Heintzelman
Inventor： Dale Lee Heintzelman
CPC classification number: B01L3/0275 , B01L3/021 , B01L9/543 , B01L2200/025 , B01L2200/026 , B01L2300/0654 , B01L2300/0858 , B01L2300/123 , B01L2300/168 , G01N1/14 , G01N21/01 , G01N21/0303 , G01N21/13 , G01N21/59 , G01N35/10 , G01N2021/0367 , G01N2035/1062 , G01N2201/0662
Abstract: This disclosure is directed to exemplary embodiments of systems, methods, techniques, processes, products and product components that can facilitate users making improved absorbance or fluorescence measurements in the field of spectroscopy with reduced (minimal) sample waste, and increased throughput, particularly in the study of biological sciences. A measuring system is provided having: a base unit with a means for locating a pipette tip; a pipette tip designed to interact with the base unit for purposes of accurate pipette tip positioning; at least one light supplying unit positioned to supply light to a liquid sample in the pipette tip and at least one light collecting unit positioned to collect light from a liquid sample in the pipette tip.
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公开(公告)号：US20160377548A1
公开(公告)日：2016-12-29
申请号：US15167721
申请日：2016-05-27
Applicant: KLA-Tencor Corporation
Inventor： Romain Sappey
CPC classification number: G01N21/6489 , G01N21/8806 , G01N21/9501 , G01N2021/6495 , G01N2021/8845 , G01N2201/06113 , G01N2201/0662
Abstract: Defect detection and photoluminescence measurement of a sample directing a beam of oblique-illumination wavelength light onto a portion of the sample, directing a beam of normal-illumination wavelength light for causing one or more photoluminescing defects of the sample to emit photoluminescent light onto a portion of the sample, collecting defect scattered radiation or photoluminescence radiation from the sample, separating the radiation from the sample into a first portion of radiation in the visible spectrum, a second portion of radiation including the normal-illumination wavelength light, and at least a third portion of radiation including the oblique-illumination wavelength light, measuring one or more characteristics of the first portion, the second portion or the third portion of radiation; detecting one or more photoluminescence defects or one or more scattering defects based on the measured one or more characteristics of the first portion, the second portion or the third portion of radiation.
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23.发明申请公开(公告)号：US20160341947A1
公开(公告)日：2016-11-24
申请号：US15224712
申请日：2016-08-01
Inventor： TAICHI SATO , YOSHIHIDE SAWADA , YASUHIKO ADACHI , HIDETO MOTOMURA
CPC classification number: G02B21/365 , G01N21/49 , G01N21/59 , G01N2201/0662 , G02B21/0008 , G02B21/06 , G02B21/086 , G02B21/26 , H04N5/2256 , H04N5/23232 , H04N5/2354 , H04N5/2356
Abstract: An image acquisition device according to the present disclosure includes a lighting system and an irradiation direction decision section. In a module, a subject and an imaging element are integrally formed. The lighting system sequentially irradiates the subject with illumination light in a plurality of different irradiation directions based on the subject such that the illumination light transmitted through the subject is incident on the imaging element. The module acquires a plurality of images according to the plurality of different irradiation directions. Before the plurality of images are acquired according to the plurality of different irradiation directions, the irradiation direction decision section decides the plurality of different irradiation directions based on a difference between a first preliminary image and a second preliminary image. The first preliminary image is acquired when the subject is irradiated with first illumination light in a first irradiation direction, and the second preliminary image is acquired when the subject is irradiated with second illumination light in a second irradiation direction.
Abstract translation: 根据本公开的图像获取装置包括照明系统和照射方向判定部。 在模块中，主体和成像元件整体形成。 照明系统基于被摄体以多个不同的照射方向的照明光顺序照射被摄体，使得透过被摄体的照明光入射到摄像元件上。 模块根据多个不同的照射方向获取多个图像。 在根据多个不同的照射方向获取多个图像之前，照射方向判定部基于第一预备图像和第二预备图像之间的差异来决定多个不同的照射方向。 当在第一照射方向上照射第一照明光时拍摄第一预备图像，并且当在第二照射方向上照射第二照明光时获取第二预备图像。
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24.发明授权Method and apparatus for detecting clots in a liquid using measured light intensity 有权使用测量光强度检测液体中凝块的方法和装置公开(公告)号：US09470674B2
公开(公告)日：2016-10-18
申请号：US14174964
申请日：2014-02-07
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Darko Klinec
IPC: G01N33/49 , G01N21/25 , G01N21/31 , G01N21/51 , G01N35/10 , G01N15/06 , G01N35/02 , G01N21/13 , G01N15/04 , G01N35/04
CPC classification number: G01N33/491 , G01N15/06 , G01N21/13 , G01N21/253 , G01N21/3151 , G01N21/51 , G01N35/02 , G01N35/1016 , G01N2015/045 , G01N2015/0693 , G01N2035/0406 , G01N2035/1018 , G01N2201/066 , G01N2201/0662 , G01N2201/0668
Abstract: A method for detecting clots in a liquid is presented. The liquid is in a sample container. Light is irradiated having a first wavelength to the sample container by a first light source at a changeable vertical irradiating position (P_0 to P_n) such that the light irradiated by the first light source passes through the sample container along a first measurement path. An intensity of light having the first wavelength passing along the first measurement path and exiting the sample container is measured. Clots are detected in response to the measured intensity.
Abstract translation: 提出了一种用于检测液体中凝块的方法。 液体在样品容器中。 通过第一光源以可变的垂直照射位置（P_0至P_n）将第一波长的光照射到样品容器，使得由第一光源照射的光沿着第一测量路径通过样品容器。 测量具有沿着第一测量路径通过并离开样品容器的第一波长的光的强度。 根据测量的强度检测到凝块。
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公开(公告)号：US20150148627A1
公开(公告)日：2015-05-28
申请号：US14091645
申请日：2013-11-27
Applicant: UNIVERSITEIT GENT
Inventor： Roeland BAETS , Eva RYCKEBOER
IPC: A61B5/145 , B01L3/00 , A61B5/1459
CPC classification number: A61B5/14532 , A61B5/14503 , A61B5/1459 , A61B5/150022 , A61B5/157 , A61B2562/04 , B01L3/5027 , G01N21/03 , G01N21/274 , G01N2201/0662
Abstract: A sensing system and method for sensing a component in a liquid is disclosed. The system comprises a microfluidic channel, the microfluidic channel comprising a first end and a second end, wherein the microfluidic channel is open at the first end and closed at the second end. The system also comprises at least one measurement sensor positioned adjacent the first end, the measurement sensor being arranged for detecting a measurement signal and a reference sensor positioned in the microfluidic channel adjacent the second end, the reference sensor being arranged for detecting a reference signal of the liquid. The system further is configured for combining the measurement signal and the reference signal so as to filter out background influences.
Abstract translation: 公开了用于感测液体中的组分的感测系统和方法。 所述系统包括微流体通道，所述微流体通道包括第一端和第二端，其中所述微流体通道在所述第一端开放并且在所述第二端封闭。 所述系统还包括邻近所述第一端定位的至少一个测量传感器，所述测量传感器被布置用于检测位于所述微流体通道中的测量信号和参考传感器，所述参考传感器邻近所述第二端，所述参考传感器被布置用于检测参考信号 液体。 该系统还被配置为组合测量信号和参考信号，以便滤除背景影响。
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Patent Agency Ranking
26.发明申请System and Method for Defect Detection and Photoluminescence Measurement of a Sample 有权样品的缺陷检测和光致发光测量的系统和方法公开(公告)号：US20150001421A1
公开(公告)日：2015-01-01
申请号：US14212496
申请日：2014-03-14
Applicant: KLA-Tencor Corporation
Inventor： Romain Sappey
CPC classification number: G01N21/6489 , G01N21/8806 , G01N21/9501 , G01N2021/6495 , G01N2021/8845 , G01N2201/06113 , G01N2201/0662
Abstract: Defect detection and photoluminescence measurement of a sample directing a beam of oblique-illumination wavelength light onto a portion of the sample, directing a beam of normal-illumination wavelength light for causing one or more photoluminescing defects of the sample to emit photoluminescent light onto a portion of the sample, collecting defect scattered radiation or photoluminescence radiation from the sample, separating the radiation from the sample into a first portion of radiation in the visible spectrum, a second portion of radiation including the normal-illumination wavelength light, and at least a third portion of radiation including the oblique-illumination wavelength light, measuring one or more characteristics of the first portion, the second portion or the third portion of radiation; detecting one or more photoluminescence defects or one or more scattering defects based on the measured one or more characteristics of the first portion, the second portion or the third portion of radiation.
Abstract translation: 样品的缺陷检测和光致发光测量将倾斜照明波长的光束引导到样品的一部分上，引导正常照明波长的光束，以使样品的一个或多个光致发光缺陷发射光致发光光到一部分上 收集来自样品的缺陷散射辐射或光致发光辐射，将来自样品的辐射分离成可见光谱中的辐射的第一部分，包括正常照明波长的光的第二部分辐射，以及至少三分之一 测量包括倾斜照明波长光的辐射部分，测量第一部分，第二部分或第三部分辐射的一个或多个特性; 基于所测量的第一部分，第二部分或第三部分辐射的一个或多个特性来检测一个或多个光致发光缺陷或一个或多个散射缺陷。
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公开(公告)号：US08908184B2
公开(公告)日：2014-12-09
申请号：US13305970
申请日：2011-11-29
Applicant: Ralf Bernhard , Achim Gahr
Inventor： Ralf Bernhard , Achim Gahr
CPC classification number: G01N21/8507 , G01N21/59 , G01N2201/0662
Abstract: An absorption measurement system, flexibly usable over a large measuring range, for measuring at least one property of a medium reflected in its absorption behavior, especially a property such as an absorption coefficient (μ). The absorption measurement system comprises: a measuring chamber filled with the medium in measurement operation, in which radiatable beam paths usable as measuring paths and of different lengths, extend completely through the medium; a transmitting unit, which transmits radiation along the measuring paths through measuring chamber in measurement operation; a measuring and receiving unit, which receives radiation passing through measuring chamber on the measuring paths and measures its radiation intensities dependent on the property of the medium and the lengths of the measuring paths; and a measuring electronics, which determines the property based on the measured radiation intensities and the lengths of measuring paths.
Abstract translation: 一种吸收测量系统，可在大的测量范围内灵活使用，用于测量其吸收行为反映的介质的至少一种性质，特别是吸收系数（μ）等特性。 吸收测量系统包括：在测量操作中填充介质的测量室，其中可用作测量路径和不同长度的可辐射光束路径完全延伸穿过介质; 发射单元，其在测量操作中通过测量室沿着测量路径传输辐射; 测量和接收单元，其接收通过测量路径上的测量室的辐射，并根据介质的性质和测量路径的长度测量其辐射强度; 以及测量电子器件，其基于测量的辐射强度和测量路径的长度来确定特性。
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公开(公告)号：US20120140228A1
公开(公告)日：2012-06-07
申请号：US13305970
申请日：2011-11-29
Applicant: Ralf Bernhard , Achim Gahr
Inventor： Ralf Bernhard , Achim Gahr
IPC: G01N21/59
CPC classification number: G01N21/8507 , G01N21/59 , G01N2201/0662
Abstract: An absorption measurement system, flexibly usable over a large measuring range, for measuring at least one property of a medium reflected in its absorption behavior, especially a property such as an absorption coefficient (μ). The absorption measurement system comprises: a measuring chamber filled with the medium in measurement operation, in which radiatable beam paths usable as measuring paths and of different lengths, extend completely through the medium; a transmitting unit, which transmits radiation along the measuring paths through measuring chamber in measurement operation; a measuring and receiving unit, which receives radiation passing through measuring chamber on the measuring paths and measures its radiation intensities dependent on the property of the medium and the lengths of the measuring paths; and a measuring electronics, which determines the property based on the measured radiation intensities and the lengths of measuring paths.
Abstract translation: 一种吸收测量系统，可在大的测量范围内灵活使用，用于测量其吸收行为反映的介质的至少一种性质，特别是吸收系数（μ）等特性。 吸收测量系统包括：在测量操作中填充介质的测量室，其中可用作测量路径和不同长度的可辐射光束路径完全延伸穿过介质; 发射单元，其在测量操作中通过测量室沿着测量路径传输辐射; 测量和接收单元，其接收通过测量路径上的测量室的辐射，并根据介质的性质和测量路径的长度测量其辐射强度; 以及测量电子器件，其基于测量的辐射强度和测量路径的长度来确定特性。
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29.发明申请Method and apparatus for noninvasively measuring a concentration of a blood component 有权用于非侵入性测量血液成分浓度的方法和装置公开(公告)号：US20040186364A1
公开(公告)日：2004-09-23
申请号：US10802920
申请日：2004-03-18
Inventor： Kye-jin Jeon , Gil-won Yoon , In-duk Hwang , Sang-joon Han
IPC: A61B005/00
CPC classification number: A61B5/14532 , A61B5/0053 , A61B5/107 , A61B5/14546 , A61B5/1455 , A61B5/1495 , A61B2560/0223 , G01N21/359 , G01N2021/036 , G01N2021/3144 , G01N2201/0662
Abstract: In an apparatus and method of noninvasively measuring a concentration of a blood component, the method includes (a) varying a thickness of a body part of a subject, measuring absorption spectrums at different thicknesses of the body part, obtaining a first differential absorption spectrum between the absorption spectrums measured at different thicknesses, actually measuring concentrations of the blood component, and establishing a statistical model using the first differential absorption spectrum and the actually measured concentrations; and (b) estimating the concentration of the blood component using a second differential absorption spectrum obtained with respect to the body part based on the statistical model.
Abstract translation: 在非侵入性地测量血液成分浓度的装置和方法中，该方法包括：（a）改变被检体的身体部位的厚度，测量身体部位的不同厚度的吸收光谱，获得第一差异吸收光谱， 在不同厚度下测量的吸收光谱，实际测量血液成分的浓度，并使用第一个差示吸收光谱和实际测量的浓度建立统计模型; 和（b）基于统计模型使用相对于身体部位获得的第二差分吸收光谱估计血液成分的浓度。
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公开(公告)号：US4966462A
公开(公告)日：1990-10-30
申请号：US310128
申请日：1989-02-15
Applicant: Vincent J. Novick
Inventor： Vincent J. Novick
CPC classification number: G01N15/06 , G01F1/661 , G01F1/74 , G01N21/534 , G01N2015/0046 , G01N21/85 , G01N2201/0662
Abstract: A method and apparatus for using the light extinction measurements from two or more light cells positioned along a gasflow chamber in which the gas volumetric rate is known to determine particle number concentration and mass concentration of an aerosol independent of extinction coefficient and to determine estimates for particle size and mass concentrations. The invention is independent of particle size. This invention has application to measurements made during a severe nuclear reactor fuel damage test.
Abstract translation: 一种用于使用沿着气流室定位的两个或更多个光单元的消光测量的方法和装置，其中已知气体体积速率确定独立于消光系数的气溶胶的粒子数浓度和质量浓度，并且确定颗粒的估计值 大小和质量浓度。 本发明独立于粒度。 本发明适用于在严重核反应堆燃料损坏试验期间进行的测量。
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