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公开(公告)号：US20180050038A1
公开(公告)日：2018-02-22
申请号：US15555241
申请日：2016-03-02
Inventor： Fernanda FESTA , Joshua LABAER , Jin PARK , Femina RAUF
IPC: A61K31/519 , A61K31/517
CPC classification number: A61K31/519 , A61K31/517
Abstract: Disclosed herein are methods of treating diseases that exhibit over-activation of the ERBB4 pathway, such as breast cancer and lung cancer. The method comprises administering to a subject having a disease that exhibits over-activation of the ERBB4 pathway and a gene expression profile consistent with an ERBB4-sensitive profile a therapeutically effective amount of an ERBB4 inhibitor, wherein the disease is effectively treated. Gene expression profiles of ERBB4-sensitive cells and microarrays suitable for protein-tyrosine kinases are also provided.
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公开(公告)号：US09899614B2
公开(公告)日：2018-02-20
申请号：US14913306
申请日：2014-08-21
Applicant: Arizona Board of Regents on behalf of Arizona State University , Universal Display Corporation
Inventor： Jian Li , Guijie Li , Jason Brooks
CPC classification number: H01L51/0087 , A61K31/4427 , C07F15/0086 , C09K11/06 , C09K2211/1007 , C09K2211/1029 , C09K2211/1044 , C09K2211/185 , H01L51/5016 , Y02E10/549
Abstract: Multidentate metal complexes useful as phosphorescent emitters in display and lighting applications have the structures as described herein. Multidentate metal complexes and compositions including one or more of the complexes described herein can be useful as emitters in organic light emitting diodes (OLEDs), displays and lighting applications, and photovoltaic devices. Generally, a chemical structural change will affect the electronic structure of the compounds, which thereby affects the optical properties of the compounds (e.g., emission and absorption spectra). Thus, the compounds described herein can be tailored or tuned to a particular emission or absorption energy. In some aspects, the optical properties of the compounds disclosed herein can be tuned by varying the structure of the ligand surrounding the metal center.
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公开(公告)号：US20180002709A1
公开(公告)日：2018-01-04
申请号：US15545275
申请日：2016-01-22
Inventor： Sidney HECHT , Larisa (Liza) DEDKOVA , Rumit MAINI , Sandipan ROY CHOWDHURY , Rakesh PAUL
IPC: C12N15/67 , C12N9/06 , C07D277/593 , C12N15/11 , C07D263/34
Abstract: Modified ribosomes that were selected using a dipeptidyl-puromycin aminonucleoside are used to mediate site-specific incorporation of one or more peptides and peptidomimetics into protein in a cell free translation system. In addition, new fluorescent dipeptidomimetics have been synthesized and incorporated into proteins, as well as modified proteins containing one or more non-naturally occurring dipeptides.
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公开(公告)号：US20170363631A1
公开(公告)日：2017-12-21
申请号：US15534203
申请日：2015-12-09
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , NATIONAL INSTITUTES OF HEALTH
Inventor： Joshua LaBaer , Jie Wang , Ji Qiu , Garrick Wallstrom , Karen Anderson , Jin Park , Jonine Figueroa
IPC: G01N33/574 , C12Q1/68 , C07K16/30 , C12N15/11
CPC classification number: G01N33/57415 , C07K16/3015 , C12N15/11 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G01N33/564
Abstract: Cancer patients make antibodies to tumor-derived proteins that are potential biomarkers for early detection. Twenty-eight antigens have been identified as potential biomarkers for the early detection of basal-like breast cancer (Tables 1, 2). Also, a 13-AAb classifier has been developed that differentiate patients with BLBC from healthy controls with 33% sensitivity at 98% specificity (Table 3).
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295.发明授权公开(公告)号：US09838760B2
公开(公告)日：2017-12-05
申请号：US14961706
申请日：2015-12-07
Inventor： Adolph Seema , Martin Reisslein
IPC: H04N21/235 , H04N21/845 , G11B27/10 , H04N21/6587 , H04N21/643 , H04N21/262 , H04N21/658
CPC classification number: H04N21/8456 , G11B27/10 , H04N21/26258 , H04N21/64322 , H04N21/6581 , H04N21/6587
Abstract: A media network platform is disclosed. The media network platform utilizes a computing device comprising at least one memory for storing instructions that are executed by at least one processor. Media data is retrieved from at least one data source. A plurality of media segments are created from the media data with each of the media segments being independently playable. A plurality of unique identifiers is assigned to each of the respective media segments. A request is received to transmit a media segment of the plurality of media segments for playback with the request including information about a unique identifier assigned to the media segment. The media segment is transmitted using the unique identifier. The media segment comprises a portion of a video derived from the media data and comprises any specific time interval of the video.
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Patent Agency Ranking
公开(公告)号：US09833895B2
公开(公告)日：2017-12-05
申请号：US14438958
申请日：2013-10-28
Inventor： Panagiotis Artemiadis , Gerald O'Neill
CPC classification number: B25J3/00 , A61F5/01 , B25J9/0081 , B25J11/00 , B25J17/00 , G05B2219/40305 , Y10T29/49828 , Y10T403/32114
Abstract: Embodiments of a coupling system include a brace member, a plurality of coupling members, and a plurality of magnetic bodies that permit an individual to be attached or detached from a robotic device. The coupling system may serve as a detachable interface between an individual engaged to the robotic device.
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公开(公告)号：US20170309154A1
公开(公告)日：2017-10-26
申请号：US15492105
申请日：2017-04-20
Inventor： Xuan Zhong , William Yost , Michael Dorman , Julie Liss , Visar Berisha
CPC classification number: G08B21/182 , G09B5/00 , G09B19/04 , G10L25/78 , G10L2025/783
Abstract: Disclosed herein are speech therapeutic devices and methods. In one aspect, the speech therapeutic device includes audio input circuitry, signal processing circuitry, and stimulus circuitry. In certain embodiments, the audio input circuitry is configured to provide an input signal that is indicative of speech provided by a user and the signal processing circuitry is configured to utilize a reconfigurable rule that includes a condition, receive the input signal, process the input signal using the reconfigurable rule, and provide an alert signal responsive to attainment of the condition. The stimulus circuitry is configured to receive the alert signal and provide a stimulus to the user. The signal processing circuitry is additionally configured to (i) receive the reconfigurable rule from a communication network, and/or (ii) generate a record indicative of the alert signal, store the record in a memory, and send the record to a communication network.
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公开(公告)号：US20170290151A1
公开(公告)日：2017-10-05
申请号：US15625924
申请日：2017-06-16
Inventor： Hanqing JIANG , Cheng LV , Hongyu YU
CPC classification number: H05K1/11 , H01L23/145 , H01L23/49866 , H01L23/5387 , H01M2/202 , H05K1/0283 , H05K1/09 , H05K1/14 , H05K2201/0314 , H05K2201/0394 , H05K2201/09263 , H05K2201/09945 , H05K2201/10037
Abstract: The invention provides an electronic device that includes a first functional body, a second functional body, and at least one connection member connecting the first functional body to the second functional body. The at least one connection member has a spiral pattern, and is suspended in air to allow tor stretching, flexing or compressing.
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299.发明申请公开(公告)号：US20170290049A1
公开(公告)日：2017-10-05
申请号：US15476611
申请日：2017-03-31
Inventor： Martin Reisslein , Akhilesh Thyagaturu
Abstract: A new access networking framework is provided for supporting small cell deployments based on the sharing of network resources. A smart gateway framework flexibly accommodates eNB connections and dynamically assigns uplink transmission resources to the eNBs. Novel techniques are also introduced for sharing the small cell infrastructures among multiple operators through virtualization and SDN based reconfiguration.
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公开(公告)号：US20170212943A1
公开(公告)日：2017-07-27
申请号：US15412955
申请日：2017-01-23
Inventor： Jundong Li , Xia Hu , Jiliang Tang , Huan Liu
IPC: G06F17/30
CPC classification number: G06F16/248 , G06F16/22 , G06F16/24568 , G06F16/24578 , G06F16/9024 , G06F16/9535
Abstract: Systems and methods for exploiting link information in streaming feature selection, resulting in a novel unsupervised streaming feature selection framework are disclosed.
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