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公开(公告)号：US20150374495A1
公开(公告)日：2015-12-31
申请号：US14846853
申请日：2015-09-07
Applicant: Sorin Group Italia S.r.l.
Inventor： Xavier Ruyra Baliarda , Monica Achiluzzi , Laura Ghione
IPC: A61F2/24
CPC classification number: A61F2/2457 , A61F2/2412 , A61F2/2445 , A61F2/2448 , A61F2/2466
Abstract: Described is a prosthetic device and methods for repairing a mitral valve having an annulus, leaflets, and chordae tendinae. The device comprises an elongate band including a plurality of reference elements that are located along the elongate band and protrude inwardly with respect thereto towards a center of the annulus, the plurality of reference elements being adapted to receive a corresponding plurality of artificial cords that are tied onto the reference elements and the plurality of reference elements adapted to be cut or removed in order to release the tied artificial cords.
Abstract translation: 描述了一种修复装置和修复具有环状，小叶和腱索的二尖瓣的方法。 该装置包括细长带，其包括沿着细长带定位并相对于其朝向环的中心向内突出的多个参考元件，多个参考元件适于接收相应的多个被连接的人造绳 到参考元件和适于被切割或移除的多个参考元件以便释放被连接的人造绳。
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公开(公告)号：US09162022B2
公开(公告)日：2015-10-20
申请号：US13750531
申请日：2013-01-25
Applicant: Sorin Group Italia S.r.l. , Politecnico di Milano
Inventor： Stefano Reggiani , Claudio Silvestri , Alberto Giri , Alberto Redaelli , Gianfranco Beniamino Fiore
CPC classification number: A61M1/1698 , A61M1/322 , A61M1/3627
Abstract: An oxygenator combines, in a single structure, a heat exchanger, a gas exchanger, an arterial filter, and a filter frame. Such an oxygenator permits fewer fluid connections and thus may simplify an extracorporeal blood circuit, including a heart-lung machine and a blood reservoir, in which it is used. In some embodiments, the oxygenator may be configured to include multiple purge ports for purging bubbles both before and after filtering the blood.
Abstract translation: 氧合器在单个结构中结合了热交换器，气体交换器，动脉过滤器和过滤器框架。 这种氧合器允许更少的流体连接，并且因此可以简化体外血液回路，包括使用它的心肺机器和血液储存器。 在一些实施例中，氧合器可以被配置为包括用于在过滤血液之前和之后净化气泡的多个吹扫端口。
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公开(公告)号：US09138314B2
公开(公告)日：2015-09-22
申请号：US14176533
申请日：2014-02-10
Applicant: Sorin Group Italia S.r.l.
Inventor： Giovanni Rolando , Paolo Gaschino , Monica Achiluzzi , Felice Giuseppe Carlino
CPC classification number: A61F2/243 , A61F2/06 , A61F2/064 , A61F2/2409 , A61F2/2427 , A61F2/2436 , A61F2002/9522 , Y10T29/49412
Abstract: A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve.
Abstract translation: 用于植入假体血管导管的套件包括用于联接到具有环形部分的假体瓣膜的假体血管导管。 导管包括用于接收阀的端子套环构件。 套件还包括保持器，其包括轴和毂，包括构造成容纳人造瓣膜的接收部分。 导管安装在保持器上，使得至少一部分导管缠绕在毂的接收部分上。 套筒构件在对应于轮毂的接收部分的位置中安装到导管上，并且套环构件的一部分被卷绕或折叠在套筒构件上。 套筒构件可以从轮毂滑动以展开套环构件，使得其围绕假肢瓣膜的环形部分设置。
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公开(公告)号：US09114010B2
公开(公告)日：2015-08-25
申请号：US13849461
申请日：2013-03-22
Applicant: Sorin Group Italia S.r.l.
Inventor： Paolo Gaschino , Andrea Mariotto , Giovanni Rolando , Massimiliano Ares
CPC classification number: A61F2/2427 , A61F2/0095 , A61F2/2412 , A61F2002/9522
Abstract: A kit for facilitating crimping of a prosthetic heart valve for implantation at an aortic valve site in a human heart, the aortic valve site including a plurality of valve sinuses, the kit comprising a prosthetic aortic heart valve having a tubular structure and a first central axis including an anchoring structure comprising an annular outflow member, an annular inflow member, and a plurality of axial connection formations arranged in pairs angularly distributed around the central axis, and a plurality of leaflets coupled to the anchoring structure and adapted to substantially allow blood flow in a first direction and to substantially prevent blood flow in a second direction. The kit further includes a holder member comprising a first disc support member that includes a central hub and a plurality of bridge elements, wherein the hub and the bridge elements extend axially from opposite sides of the disc support member; and a second ring support member that includes receptacles for coupling with the bridge elements, and a plurality of finger formations protruding axially from the ring member and extending lengthwise along at least a portion of the prosthetic aortic heart valve.
Abstract translation: 一种用于促进假体心脏瓣膜的压接以用于植入人心脏中的主动脉瓣部位的试剂盒，所述主动脉瓣部位包括多个瓣膜窦，该试剂盒包括具有管状结构的假体主动脉瓣心脏瓣膜和第一中心轴线 包括锚定结构，其包括环形流出构件，环形流入构件以及围绕所述中心轴线成角度地分布成对的多个轴向连接结构，以及耦合到所述锚定结构并且适于基本上允许血液流动的多个叶片 第一方向并且基本上防止在第二方向上的血液流动。 该套件还包括保持器构件，其包括第一盘支撑构件，该第一盘支撑构件包括中心轮毂和多个桥接元件，其中轮毂和桥接元件从盘支撑构件的相对侧轴向延伸; 以及第二环支撑构件，其包括用于与所述桥接元件联接的插座，以及从所述环构件轴向突出并沿所述假体主动脉瓣心脏的至少一部分纵向延伸的多个指状结构。
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公开(公告)号：US20150196703A1
公开(公告)日：2015-07-16
申请号：US14668933
申请日：2015-03-25
Applicant: Sorin Group Italia S.r.l.
Inventor： Claudio Silvestri , Gabriele Tommasi
CPC classification number: A61M1/3638 , A61M1/1698 , A61M1/3627 , A61M1/3632 , A61M1/3666 , A61M2202/0413 , A61M2205/75
Abstract: A blood reservoir may be used in combination with other elements such as a heart lung machine (HLM), oxygenator, heat exchanger, arterial filter and the like to form an extracorporeal blood circuit that may be employed in a procedure such as a bypass procedure. The blood reservoir may be configured to receive, filter and store blood from a number of sources including vent blood (from within the heart), venous blood (from a major vein), purge blood (from a sampling line) and cardiotomy or suction blood (from the surgical field).
Abstract translation: 血液储存器可以与诸如心肺机（HLM），充氧器，热交换器，动脉过滤器等的其它元件组合使用，以形成可用于诸如旁路手术的过程中的体外血液回路。 血液储存器可以被配置为接收，过滤和储存来自多个来源的血液，包括排出血液（来自心脏内），静脉血（来自主要静脉），清除血液（来自取样管线）和心脏切开术或抽吸血液 （从手术领域）。
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Patent Agency Ranking
36.发明申请公开(公告)号：US20140370599A1
公开(公告)日：2014-12-18
申请号：US14341974
申请日：2014-07-28
Applicant: Sorin Group Italia S.r.l.
Inventor： Marina Strasly , Giovanni Rolando
IPC: A61K35/12
CPC classification number: A61L27/3687 , A61K35/12 , A61L27/3683
Abstract: A method of treating a biological tissue for biological prostheses includes steps of fixation of the biological tissue via a fixing solution including glutaraldehyde and detoxification of the fixed biological tissue via treatment with a detoxifying solution. The detoxification step includes one or both of eliminating phospholipids via treatment with an elimination solution and a treatment with a detoxifying solution. The elimination solution includes 1,2-octanediol and ethanol. The detoxifying solution includes taurine or homocysteic acid.
Abstract translation: 用于生物假体处理生物组织的方法包括通过包含戊二醛的固定溶液固定生物组织并通过用解毒溶液处理来固定固定的生物组织的步骤。 解毒步骤包括通过用消除溶液处理和用解毒溶液处理来消除磷脂的一种或两种。 消除溶液包括1,2-辛二醇和乙醇。 解毒溶液包括牛磺酸或高半胱氨酸。
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公开(公告)号：US20140227133A1
公开(公告)日：2014-08-14
申请号：US14156937
申请日：2014-01-16
Applicant: Sorin Group Italia S.r.l. , Politecnico di Milano
Inventor： Stefano Reggiani , Gianfranco Beniamino Fiore , Alberto Redaelli , Christian Baiotto
IPC: A61M1/16
CPC classification number: A61M1/1698 , A61M1/32 , A61M1/3627 , A61M1/3666 , A61M1/3667 , A61M2206/10 , A61M2206/14 , A61M2206/16 , A61M2206/18 , A61M2206/20 , B01D63/02 , B01D2313/08 , B01D2313/19 , B01D2313/32 , B01D2313/38 , F28D7/103 , F28D7/1623 , F28D21/0015 , F28D2021/005 , F28F13/06 , F28F21/06 , F28F21/062 , F28F2260/00 , Y10S128/03 , Y10S261/28
Abstract: A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path.
Abstract translation: 血液处理装置可以包括热交换器和气体交换器。 热交换器和气体交换器中的至少一个可以被配置成赋予径向分量以吹动通过热交换器和/或气体交换器。 热交换器可以被配置为使血液流动遵循螺旋流动路径。
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公开(公告)号：US20140207011A1
公开(公告)日：2014-07-24
申请号：US14222598
申请日：2014-03-22
Applicant: Sorin Group Italia S.r.l.
Inventor： Giovanni Righini , Felice Giuseppe Carlino , Giovanni Rolando
CPC classification number: A61F2/2496 , A61B5/02 , A61B5/103 , A61B5/1076 , A61B5/6871
Abstract: A device for measuring an internal dimension of a native cardiac valve annulus includes an elongated support member having a proximal portion and a distal portion. A measuring portion is coupled to the distal portion, and an indicator is coupled to the proximal portion of the support member. The measuring portion is biased towards a deployed configuration such that when deployed it applies an outwardly directed radial force to the native valve annulus.
Abstract translation: 用于测量天然心脏瓣膜环的内部尺寸的装置包括具有近端部分和远端部分的细长支撑构件。 测量部分联接到远端部分，并且指示器联接到支撑构件的近端部分。 测量部分被朝向展开构型偏置，使得当其展开时，其将向外指向的径向力施加到自然瓣膜环。
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公开(公告)号：US20130268068A1
公开(公告)日：2013-10-10
申请号：US13835593
申请日：2013-03-15
Applicant: SORIN GROUP ITALIA S.R.L.
Inventor： Andrea Marchisio , Giovanni Rolando , Paolo Gaschino
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2427
Abstract: A support device for implanting a stentless heart valve prosthesis having three leaflets adapted for coapting and defining three corresponding commissures is disclosed. The support device includes a shaft defining a manipulation axis, the shaft having a proximal portion and a distal portion, and three support formations integrally formed and extending from the proximal end of the shaft, the support formations angularly distributed about the manipulation axis of the shaft, such that each of the support formations correspond to locations of each of the commissures of the stentless heart valve prosthesis. The shaft includes a connection portion flexibly connecting the shaft and the support formations to permit a displacement of the manipulation axis with respect to the support formations. The shaft, the plurality of support formations and the connection portion are integrally formed from a single tubular element.
Abstract translation: 公开了一种用于植入无支架心脏瓣膜假体的支撑装置，其具有三个适用于起皱和限定三个相应连合的小叶。 所述支撑装置包括限定操作轴的轴，所述轴具有近端部分和远端部分，以及从所述轴的近端一体地形成并延伸的三个支撑结构，所述支撑结构围绕所述轴的操纵轴线成角度地分布 ，使得每个支撑结构对应于无支架式心脏瓣膜假体的每个连合的位置。 轴包括连接部分，该连接部分柔性地连接轴和支撑结构，以允许操纵轴相对于支撑结构的位移。 轴，多个支撑结构和连接部分由单个管状元件整体形成。
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公开(公告)号：US12233194B2
公开(公告)日：2025-02-25
申请号：US18119648
申请日：2023-03-09
Applicant: Sorin Group Italia S.r.l.
Inventor： Stephen W. Berch , Thierry Dupoux , Elisa Maculan , Giampaolo Simonini
Abstract: A system including tubing and a filter configured to be fluidly coupled to a vacuum source and to a heater/cooler unit by the tubing. The filter includes a filter container having negative air pressure in the filter container provided by the vacuum source to pull aerosol from the heater/cooler unit into the filter container and eliminate and/or reduce the aerosol emitted from the heater/cooler unit.
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