公开(公告)号：US08224461B2

公开(公告)日：2012-07-17

申请号：US12703544

申请日：2010-02-10

Applicant: Torsten Scheuermann

Inventor： Torsten Scheuermann

IPC: A61N1/00

CPC classification number: A61N1/056 ,  A61B5/042 ,  A61B2562/0209

Abstract: The embodiments herein relate to an electrode having a porous coating including a fiber mesh, a multi-layer coating, and an outer coating, and a method of making the same. The various electrode coating embodiments include pores in the coating that prevent access by protein or cells while allowing for ion and/or liquid access.

Abstract translation: 本文的实施方案涉及具有包括纤维网，多层涂层和外涂层的多孔涂层的电极及其制造方法。 各种电极涂覆实施方案包括涂层中的孔，其阻止蛋白质或细胞进入，同时允许离子和/或液体进入。

公开(公告)号：US20110245905A1

公开(公告)日：2011-10-06

申请号：US13051496

申请日：2011-03-18

Applicant: Jan Weber ,  Liliana Atanasoska ,  James Lee Shippy, III ,  Torsten Scheuermann ,  Daniel J. Gregorich ,  Michael P. Meyer

Inventor： Jan Weber ,  Liliana Atanasoska ,  James Lee Shippy, III ,  Torsten Scheuermann ,  Daniel J. Gregorich ,  Michael P. Meyer

IPC: A61F2/82 ,  B05D3/00 ,  B44C1/22 ,  B23P11/00

CPC classification number: A61L31/088 ,  A61L31/044 ,  A61L31/06 ,  A61L31/10 ,  A61L31/148 ,  A61L31/16 ,  Y10T29/49826 ,  C08L67/04

Abstract: Among other things, a bio-erodible implantable endoprosthesis comprises a member that includes (a) a core having a surface, and (b) a bio-erodible metal on a least a portion of the surface of the core, wherein the bio-erodible metal erodes more slowly than the core and includes openings through which physiological fluids can access the core upon implantation.

Abstract translation: 除其他之外，生物可蚀刻的可植入内用假体包括一种构件，其包括（a）具有表面的芯，和（b）所述芯的表面的至少一部分上的生物可侵蚀金属，其中所述生物可蚀刻 金属腐蚀比核心更慢，并且包括生理流体在植入时可通过其进入核心的开口。

公开(公告)号：US20110238151A1

公开(公告)日：2011-09-29

申请号：US13053791

申请日：2011-03-22

Applicant: Torsten Scheuermann ,  Jan Weber ,  Charles Deng ,  Jonathan S. Stinson ,  Steven R. Larsen ,  Dennis A. Boismier ,  Jacob D. Edick

Inventor： Torsten Scheuermann ,  Jan Weber ,  Charles Deng ,  Jonathan S. Stinson ,  Steven R. Larsen ,  Dennis A. Boismier ,  Jacob D. Edick

IPC: A61F2/82

CPC classification number: A61L31/148 ,  A61F2/91 ,  A61F2210/0004 ,  A61L31/022 ,  A61L31/088

Abstract: An endoprosthesis includes an expandable tubular body defined by a plurality of struts. In some embodiments, the expandable tubular body includes a bioerodible metal that has at least a first surface region and a second surface region. The first and second surface regions can have different surface oxide compositions. In some embodiments, the first portion has a thermally altered microstructure and the second portion has a wrought microstructure. The thermally altered microstructure can be a cast microstructure comprising dendritic grains. The first portion forms at least a portion of an outer surface of the expandable tubular body. In some embodiments, the expandable tubular body includes iron or a bioerodible iron alloy and at least one surface of the expandable tubular body includes a substantially uniform coating of iron(III) oxide.

Abstract translation: 内假体包括由多个支柱限定的可扩张管状体。 在一些实施例中，可扩张管状体包括具有至少第一表面区域和第二表面区域的生物浸渍金属。 第一和第二表面区域可以具有不同的表面氧化物组成。 在一些实施例中，第一部分具有热改变的微结构，第二部分具有锻造微结构。 热改变的微结构可以是包含树枝状晶粒的铸造微结构。 第一部分形成可扩张管状体的外表面的至少一部分。 在一些实施例中，可膨胀管状体包括铁或生物腐蚀性铁合金，并且可膨胀管体的至少一个表面包括基本均匀的氧化铁（III）涂层。

公开(公告)号：US20110087191A1

公开(公告)日：2011-04-14

申请号：US12902454

申请日：2010-10-12

Applicant: Torsten SCHEUERMANN

Inventor： Torsten SCHEUERMANN

IPC: A61L29/16 ,  A61M25/10

CPC classification number: A61M25/10 ,  A61L29/16 ,  A61L2300/416 ,  A61L2400/16 ,  A61M2025/105 ,  A61M2025/1081 ,  C08L2201/12

Abstract: A medical device is provided comprising a catheter, a balloon mounted on the catheter, and a sheath comprising a shape memory material, the sheath being located around the balloon. The sheath has a protective condition in which the sheath forms a plurality of pockets in a generally closed position and an activated condition in which the pockets are in a generally open position. A therapeutic agent is located within the generally closed pockets of the sheath when the sheath is in the protective condition. The therapeutic agent is exposed for delivery to a target site when the sheath is transitioned from the protective condition to the activated condition.

Abstract translation: 提供了一种医疗装置，其包括导管，安装在导管上的球囊，以及包括形状记忆材料的护套，护套位于气囊周围。 护套具有保护条件，其中护套在大致闭合位置形成多个口袋，并且其中口袋处于大致打开位置的启动状态。 当护套处于保护状态时，治疗剂位于鞘的通常封闭的袋内。 当鞘从保护状态转变为活化状态时，将治疗剂暴露于靶向部位。

公开(公告)号：US20100125319A1

公开(公告)日：2010-05-20

申请号：US12576918

申请日：2009-10-09

Applicant: Torsten Scheuermann

Inventor： Torsten Scheuermann

IPC: A61N1/05 ,  H01R43/00

CPC classification number: A61N1/0565 ,  A61N2001/0578 ,  Y10T29/49117

Abstract: The embodiments herein relate to a coated electrode including a structured surface and a conductive layer and a method of making the same. The various electrode embodiments can include a surface topography that minimizes tissue attachment and thus facilitates removal of the electrode.

Abstract translation: 本文的实施方案涉及包括结构化表面和导电层的涂覆电极及其制备方法。 各种电极实施例可以包括最小化组织附着并因此有助于电极移除的表面形貌。

公开(公告)号：US20090269383A1

公开(公告)日：2009-10-29

申请号：US12428775

申请日：2009-04-23

Applicant: Michael Kuehling ,  Dominique SEIDEL ,  Torsten SCHEUERMANN ,  Jan WEBER

Inventor： Michael Kuehling ,  Dominique SEIDEL ,  Torsten SCHEUERMANN ,  Jan WEBER

IPC: A61K9/00 ,  B05D3/00 ,  A61P43/00

CPC classification number: A61L31/16 ,  A61L31/08 ,  A61L2300/61 ,  A61L2300/62 ,  A61L2420/02

Abstract: An expandable medical device having a particle layer disposed over a reservoir containing a therapeutic agent. The particle layer has a first porosity when the medical device is in the unexpanded configuration and a second porosity when the medical device is in the expanded configuration. The particle layer comprises a plurality of micron-sized or nano-sized particles. In certain embodiments, the particles are not connected to each other, and as such, the different porosities are provided by changes in the spacing between the particles as the medical device is expanded/unexpanded. Also disclosed are medical devices having a particle layer, wherein the particle layer comprises a plurality of encapsulated particles, and methods of coating medical devices with particles.

Abstract translation: 一种可膨胀医疗装置，其具有设置在含有治疗剂的贮器上的颗粒层。 当医疗装置处于未膨胀构型时，颗粒层具有第一孔隙度，并且当医疗装置处于膨胀构型时具有第二孔隙率。 颗粒层包含多个微米级或纳米尺寸的颗粒。 在某些实施方案中，颗粒彼此不连接，因此，当医疗装置膨胀/未膨胀时，由颗粒之间的间隔的变化提供不同的孔隙度。 还公开了具有颗粒层的医疗装置，其中所述颗粒层包含多个包封的颗粒，以及用颗粒涂覆医疗装置的方法。

公开(公告)号：US07423496B2

公开(公告)日：2008-09-09

申请号：US11270417

申请日：2005-11-09

Applicant: Torsten Scheuermann

Inventor： Torsten Scheuermann

IPC: A61B5/05

CPC classification number: G01R33/286 ,  G01R33/3628

Abstract: Systems and methods for a resonator with an adjustable capacitance for a medical device. In one embodiment, a resonator system includes a resonator device with an LC resonator circuit that has an adjustable capacitance, an inductor coil in series with the adjustable capacitance, and an adjustable capacitance control that can control the adjustable capacitance to obtain different particular capacitance values. This embodiment also includes a medical device, positioned with the resonator device, so that at least a portion of the inductor coil surrounds a space that is surrounded by at least a portion of the medical device.

Abstract translation: 用于医疗设备具有可调电容的谐振器的系统和方法。 在一个实施例中，谐振器系统包括具有可调电容的LC谐振器电路的谐振器装置，与可调电容串联的电感线圈，以及可调节的电容控制，其可以控制可调电容以获得不同的特定电容值。 该实施例还包括与谐振器装置一起定位的医疗装置，使得电感线圈的至少一部分围绕由医疗装置的至少一部分包围的空间。

公开(公告)号：US07402173B2

公开(公告)日：2008-07-22

申请号：US10364112

申请日：2003-02-10

Applicant: Torsten Scheuermann ,  Lutz Stehling

Inventor： Torsten Scheuermann ,  Lutz Stehling

IPC: A61F2/06 ,  A61M29/00

CPC classification number: A61L31/022 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2310/00598 ,  A61L31/088 ,  A61L31/18

Abstract: In a process for producing a biocompatible stent, a tubular substrate of the stent adapted for diametric expansion has a layer of a noble metal oxide formed over at least the outer surface of greater diameter of the substrate, the substrate being composed of a metal or an alloy thereof that is non-noble or less-noble than the layer's noble metal. An interface region adapted to prevent corrosion and to provide a firm bond between the surface of the substrate and the noble metal oxide layer is established, at least in part, by forming the noble metal oxide layer with a progressively varying concentration of noble metal-to-oxide with depth of the layer such that a surface of pure noble metal and negligible oxide of the layer is in closest proximity to the surface of the substrate. In one embodiment of the process, the interface region is established by forming the surface of pure noble metal and negligible oxide thereof in direct contact with the metal or alloy of the substrate surface. In another, the interface region is established by first creating an oxide of the substrate metal or alloy thereof at the substrate surface, and then forming the noble metal oxide layer as above, but in contact with the substrate metal or alloy oxide. Alternatively, the noble metal oxide layer has no progressively varying concentration but simply overlies an oxide of the substrate metal or alloy.

Abstract translation: 在制造生物相容性支架的方法中，适用于直径膨胀的支架的管状基底具有至少在基底的较大直径的外表面上形成的贵金属氧化物层，该基底由金属或 它的合金是非贵重的或比贵金属低贵的贵金属。 至少部分地通过以逐渐变化的贵金属浓度形成贵金属氧化物层，从而建立适于防止腐蚀并在衬底表面和贵金属氧化物层之间提供牢固结合的界面区域 - 至少 氧化物，其层的深度使得纯贵金属的表面和该层的可忽略的氧化物最接近衬底的表面。 在该方法的一个实施方案中，通过形成纯金属的表面和与基底表面的金属或合金直接接触的可忽略的氧化物的表面来建立界面区。 另一方面，通过首先在基板表面产生基板金属或其合金的氧化物，然后如上所述形成贵金属氧化物层，但与基板金属或合金氧化物接触来建立界面区域。 或者，贵金属氧化物层的浓度没有逐渐变化，而是简单地覆盖基板金属或合金的氧化物。

公开(公告)号：US06767360B1

公开(公告)日：2004-07-27

申请号：US09779204

申请日：2001-02-08

Applicant: Eckhard Alt ,  Torsten Scheuermann ,  Michael Kühling

Inventor： Eckhard Alt ,  Torsten Scheuermann ,  Michael Kühling

IPC: A61F206

CPC classification number: A61L31/18 ,  A61B5/055 ,  A61B5/411 ,  A61F2/88 ,  A61F2/91 ,  A61F2210/0076 ,  A61F2250/0043 ,  A61L31/022 ,  A61L31/082 ,  G01R33/285 ,  G01R33/34046 ,  G01R33/34053 ,  G01R33/34069 ,  G01R33/34076 ,  G01R33/34084

Abstract: A stent is adapted to be implanted in a duct of a human body to maintain an open lumen at the implant site, and to allow viewing body tissue and fluids by magnetic resonance imaging (MRI) energy applied external to the body. The stent constitutes a metal scaffold. An electrical circuit resonant at the resonance frequency of the MRI energy is fabricated integral with the scaffold structure of the stent to promote viewing body properties within the lumen of the stent.

Abstract translation: 支架适于植入人体的管道中，以在植入部位保持开放的腔，并且允许通过在身体外部施加的磁共振成像（MRI）能量观察体内组织和流体。 支架构成金属支架。 在MRI能量的共振频率下共振的电路与支架的支架结构一体制成，以促进支架内腔内的观察体特性。

公开(公告)号：US08668732B2

公开(公告)日：2014-03-11

申请号：US13053791

申请日：2011-03-22

Applicant: Torsten Scheuermann ,  Jan Weber ,  Charles Deng ,  Jonathan S. Stinson ,  Steven R. Larsen ,  Dennis A. Boismier ,  Jacob D. Edick

Inventor： Torsten Scheuermann ,  Jan Weber ,  Charles Deng ,  Jonathan S. Stinson ,  Steven R. Larsen ,  Dennis A. Boismier ,  Jacob D. Edick

IPC: A61F2/82

CPC classification number: A61L31/148 ,  A61F2/91 ,  A61F2210/0004 ,  A61L31/022 ,  A61L31/088

Abstract: An endoprosthesis includes an expandable tubular body defined by a plurality of struts. In some embodiments, the expandable tubular body includes a bioerodible metal that has at least a first surface region and a second surface region. The first and second surface regions can have different surface oxide compositions. In some embodiments, the first portion has a thermally altered microstructure and the second portion has a wrought microstructure. The thermally altered microstructure can be a cast microstructure comprising dendritic grains. The first portion forms at least a portion of an outer surface of the expandable tubular body. In some embodiments, the expandable tubular body includes iron or a bioerodible iron alloy and at least one surface of the expandable tubular body includes a substantially uniform coating of iron(III) oxide.

Abstract translation: 内假体包括由多个支柱限定的可扩张管状体。 在一些实施例中，可扩张管状体包括具有至少第一表面区域和第二表面区域的生物浸渍金属。 第一和第二表面区域可以具有不同的表面氧化物组成。 在一些实施例中，第一部分具有热改变的微结构，第二部分具有锻造微结构。 热改变的微结构可以是包含树枝状晶粒的铸造微结构。 第一部分形成可扩张管状体的外表面的至少一部分。 在一些实施例中，可膨胀管状体包括铁或生物腐蚀性铁合金，并且可膨胀管体的至少一个表面包括基本均匀的氧化铁（III）涂层。