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    Systems and methods for freezing, mixing and thawing biopharmaceutical material
    32.
    发明授权
    Systems and methods for freezing, mixing and thawing biopharmaceutical material 有权
    用于冷冻，混合和解冻生物药物材料的系统和方法

    公开(公告)号：US07137261B2

    公开(公告)日：2006-11-21

    申请号：US11085314

    申请日：2005-03-21

    Applicant: David C. Brown ,  Jonathan Cutting ,  Eric K. Lee ,  Nicolas Voute ,  Brian J. Woodard

    Inventor： David C. Brown ,  Jonathan Cutting ,  Eric K. Lee ,  Nicolas Voute ,  Brian J. Woodard

    IPC: F25C1/00

    CPC classification number: A01N1/02 ,  A01N1/0257 ,  A01N1/0263 ,  A01N31/02 ,  A23L3/364 ,  A23L3/365 ,  A61M1/0272 ,  A61M1/0277 ,  A61M1/0281 ,  F25B2600/07 ,  F25C1/04 ,  F25C2600/04 ,  F25D25/00 ,  F25D25/005 ,  F25D31/001 ,  F25D2331/8014 ,  F25D2400/20 ,  F25D2400/30 ,  G01N1/42 ,  A01N2300/00

    Abstract: A system for controlled freezing, storing and thawing of a biopharmaceutical material includes a cavity for receiving a container for holding the biopharmaceutical material. Further included are at least a pair of opposed surfaces facing the biopharmaceutical material holding container. At least one of the opposed surfaces includes a moveable contacting surface configured to contact the container to inhibit a clearance between the container and the movable contacting surface. Also included is at least one heat transfer surface which is thermally coupled to the biopharmaceutical material holding container when the moveable contacting surface contacts the container. Also, the cavity may be configured to receive a frame for supporting the container holding the biopharmaceutical material. Further, the system may include a driver to move the frame holding the container inside the cavity.

    Abstract translation: 用于受控冷冻，储存和解冻生物药物材料的系统包括用于容纳用于保持生物药物材料的容器的空腔。 还包括面向生物药物材料保持容器的至少一对相对表面。 相对表面中的至少一个包括可移动的接触表面，其构造成与容器接触以阻止容器和可动接触表面之间的间隙。 还包括至少一个热传递表面，当可移动接触表面接触容器时，热传递表面热耦合到生物药物材料保持容器。 此外，空腔可以被配置为容纳用于支撑容纳生物药物材料的容器的框架。 此外，系统可以包括驱动器，以将保持容器的框架移动到腔体内。

    Method and system for an atomically updated, central cache memory
    33.
    发明授权
    Method and system for an atomically updated, central cache memory 有权

    公开(公告)号：US07089365B2

    公开(公告)日：2006-08-08

    申请号：US11184578

    申请日：2005-07-19

    Applicant: David C. Brown ,  Mikhail V. Leonov ,  Michael M. Byrd

    Inventor： David C. Brown ,  Mikhail V. Leonov ,  Michael M. Byrd

    IPC: G06F12/00

    CPC classification number: G09G5/363 ,  G06F9/52 ,  G09G5/24 ,  G09G5/393 ,  G09G2360/121 ,  G09G2370/027

    Abstract: Disclosed is a central cache that is updated without the overhead of locking. Updates are “atomic” in that they cannot be interrupted part way through. Applications are always free to read data in the cache, accessing the data through a reference table. Applications do not directly update the cache, instead, they send update requests to a service routine. To update the cache, the service routine proceeds in two phases. In the first phase, the service routine prepares the new data and adds them to the cache, without updating the reference table. During the first phase, an application accessing the cache cannot “see” the new data because the reference table has not yet been updated. After the first phase is complete, the service routine performs the second phase of the update process: atomically updating the reference table. The two-phase update process leaves the cache, at all times, in a consistent state.

    Type size dependent anti-aliasing in sub-pixel precision rendering systems
    34.
    发明授权
    Type size dependent anti-aliasing in sub-pixel precision rendering systems 失效
    子像素精度渲染系统中类型大小相关的抗锯齿

    公开(公告)号：US06894701B2

    公开(公告)日：2005-05-17

    申请号：US10146424

    申请日：2002-05-14

    Applicant: David C. Brown ,  John C. Platt ,  Michael Duggan ,  Gregory Hitchcock ,  Beat Stamm

    Inventor： David C. Brown ,  John C. Platt ,  Michael Duggan ,  Gregory Hitchcock ,  Beat Stamm

    IPC: G06T5/20 ,  G06T11/20 ,  G09G3/20 ,  G09G3/36 ,  G09G5/28 ,  G09G5/30 ,  G09G5/00

    CPC classification number: G09G5/28 ,  G06T11/203 ,  G09G3/2074 ,  G09G5/30 ,  G09G2340/0457

    Abstract: Methods and systems for selecting different anti-aliasing filters to be applied to objects of image data rendered with pixel sub-component precision based on the attributes of the objects of the graphics image. For example, when rendering a character traditional anti-aliasing applied in the direction parallel to the striping of the pixel sub-components is adapted to the unique requirements of different character font sizes such that a large amount of anti-aliasing is applied to large font sizes while a small amount of anti-aliasing is provided for characters at small font sizes. Displaced sampling is utilized to determine the alpha values for a plurality of vertical samples for each RGB pixel sub-component. The selected anti-aliasing filter is applied to the alpha values to determine the luminous intensity values of the RGB pixel sub-components.

    Abstract translation: 用于基于图形图像的对象的属性来选择要应用于以像素子分量精度呈现的图像数据的对象的不同抗混叠滤波器的方法和系统。 例如，当渲染字符在与像素子组件的条纹平行的方向上应用的传统抗锯齿适应于不同字符字体​​大小的独特要求时，大量抗锯齿被应用于大字体 尺寸，同时为小字体尺寸的字符提供少量抗锯齿。 利用位移采样来确定每个RGB像素子分量的多个垂直样本的α值。 将所选的抗混叠滤波器应用于α值以确定RGB像素子分量的发光强度值。

    Long-lived rotary ball bearing for reciprocating applications and method of lubricating same
    38.
    发明授权
    Long-lived rotary ball bearing for reciprocating applications and method of lubricating same 失效
    长寿命旋转滚珠轴承用于往复式应用和润滑方法

    公开(公告)号：US06196725B1

    公开(公告)日：2001-03-06

    申请号：US09274402

    申请日：1999-03-23

    Applicant: David C. Brown

    Inventor： David C. Brown

    IPC: F16C1900

    CPC classification number: F16C33/6629 ,  F16C19/52 ,  F16C19/55 ,  F16C33/6681

    Abstract: A rotary bearing includes concentric radially spaced-apart inner, intermediate and outer rings whose opposing surfaces define inner and outer ball tracks. An inner array of balls roll along the inner track and an outer array of balls roll along the outer track and a viscous lubricant is present between the rings. When the inner and outer rings are angularly reciprocated relative to one another, the intermediate ring is moved intermittently in a selected direction about the rotation axis so that the balls recirculate about the axis and redistribute lubricant along the tracks. In a preferred embodiment, the relative angular excursion of the inner and outer rings is increased periodically beyond a selected maximum angle to effect the advancement of the intermediate ring using the lubricant as a ratcheting mechanism.

    Abstract translation: 旋转轴承包括同心径向隔开的内，中和外圈，其相对表面限定内球和外球轨。 球的内部阵列沿着内部轨道滚动，并且球的外部阵列沿着外部轨道滚动，并且环之间存在粘性润滑剂。 当内环和外环相对于彼此成角度地往复运动时，中间环围绕旋转轴线沿所选方向间歇地移动，使得球围绕轴线再循环并沿着轨道重新分布润滑剂。 在优选实施例中，内圈和外圈的相对角度偏移周期性增加超过所选择的最大角度，以使用润滑剂作为棘轮机构来实现中间环的前进。

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