公开(公告)号：US20190120784A1

公开(公告)日：2019-04-25

申请号：US16168715

申请日：2018-10-23

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart

IPC: G01N27/327 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/1495 ,  A61B5/1473 ,  A61B5/1459 ,  G01N33/66

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

公开(公告)号：US20190117133A1

公开(公告)日：2019-04-25

申请号：US16167976

申请日：2018-10-23

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart

IPC: A61B5/1495 ,  A61B5/145 ,  A61B5/00

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

公开(公告)号：US20170188921A1

公开(公告)日：2017-07-06

申请号：US15394520

申请日：2016-12-29

Applicant: DexCom, Inc.

Inventor： Shanger Wang ,  Ted Tang Lee ,  Jiong Zou

IPC: A61B5/1486 ,  C12N11/08 ,  A61B5/145 ,  C12Q1/00

CPC classification number: G01N27/3273 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2562/12 ,  A61K31/045 ,  A61K31/137 ,  A61K31/46 ,  A61K31/465 ,  A61K31/485 ,  A61K31/515 ,  A61K31/56 ,  A61K33/00 ,  A61K36/185 ,  A61K38/28 ,  C08G18/0828 ,  C08G18/12 ,  C08G18/3857 ,  C08G18/4018 ,  C08G18/44 ,  C08G18/4833 ,  C08G18/755 ,  C08L39/06 ,  C08L69/00 ,  C08L75/04 ,  C12N11/08 ,  C12Q1/002 ,  C12Q1/006 ,  G01N27/3275 ,  G01N33/66 ,  C08G18/3234

Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.

公开(公告)号：US20170188905A1

公开(公告)日：2017-07-06

申请号：US15394764

申请日：2016-12-29

Applicant: DexCom, Inc.

Inventor： Ted Tang Lee ,  Andrew Trinin Dennis ,  Shanger Wang ,  Jiong Zou

IPC: A61B5/1486 ,  A61K36/185 ,  A61K31/46 ,  A61K38/28 ,  A61B5/145 ,  A61K31/485 ,  A61K31/465 ,  A61K31/56 ,  A61K31/137 ,  A61K31/515 ,  A61K33/00 ,  A61K31/045

CPC classification number: G01N27/3273 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2562/12 ,  A61K31/045 ,  A61K31/137 ,  A61K31/46 ,  A61K31/465 ,  A61K31/485 ,  A61K31/515 ,  A61K31/56 ,  A61K33/00 ,  A61K36/185 ,  A61K38/28 ,  C08G18/0828 ,  C08G18/12 ,  C08G18/3857 ,  C08G18/4018 ,  C08G18/44 ,  C08G18/4833 ,  C08G18/755 ,  C08L39/06 ,  C08L69/00 ,  C08L75/04 ,  C12N11/08 ,  C12Q1/002 ,  C12Q1/006 ,  G01N27/3275 ,  G01N33/66 ,  C08G18/3234

Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises a biointerface layer which interfaces with a biological fluid containing the analyte to be measured. The biointerface layer comprises a biointerface polymer, wherein the biointerface polymer comprises polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The biointerface layer increases sensor longevity and decrease sensor inaccuracy by inhibiting accumulation of cells, proteins, and other biological species on the outermost layers of the sensor.

公开(公告)号：US20160338734A1

公开(公告)日：2016-11-24

申请号：US15160903

申请日：2016-05-20

Applicant: DexCom, Inc.

Inventor： Neel Shah ,  Jennifer Blackwell ,  Jonathan Hughes ,  Ted Tang Lee ,  Peter C. Simpson ,  Shanger Wang

IPC: A61B17/34 ,  A61B5/145

CPC classification number: A61B17/3468 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14865 ,  A61B2017/3456 ,  A61B2560/063 ,  A61M5/3286

Abstract: The present disclosure relates to a needle including a wall structure, a cutting edge and a blunt contour. The needle advantageously can be used to deliver a sensor (such as a glucose or other analyte sensor) through an outer skin layer and into a sensor depth in a less invasive way than prior art needles. The size of the cutting edge is balanced against a portion of the distal wall structure that has blunt contours. Thus, the needle is capable of cutting the more durable outer skin layer (first phase) and then progressively stretching open the cut for further advancement into the subcutaneous layer (second phase). When the needle is sufficiently advanced, it is retracted leaving the sensor in a desired position. Early testing has shown a reduction of “dip and recover” from glucose sensors delivered using the needle.

公开(公告)号：US20250040058A1

公开(公告)日：2025-01-30

申请号：US18916623

申请日：2024-10-15

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart ,  John Stanley Hayes

IPC: H05K3/32 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/1495 ,  A61M5/00 ,  A61M5/142 ,  A61M5/172 ,  A61M5/178 ,  A61M5/20 ,  A61M5/30 ,  A61M11/00 ,  A61M15/00 ,  A61M35/00 ,  G01N27/327 ,  G01N33/66 ,  G16H20/17 ,  G16H40/63

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

公开(公告)号：US20240293050A1

公开(公告)日：2024-09-05

申请号：US18646451

申请日：2024-04-25

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Minglian Shi ,  Sebastian Bohm ,  Maria Noel Brown Wells ,  John Patrick Majewski ,  Leah Morta Edra ,  Disha B. Sheth ,  John Michael Gray ,  Shanger Wang ,  Ted Tang Lee ,  Michael L. Moore ,  Jason Mitchell ,  Jennifer Blackwell ,  Neel Narayan Shah ,  Todd Andrew Newhouse ,  Jason Halac ,  Ryan Everett Schoonmaker ,  Paul V. Neale ,  Jiong Zou ,  Sean T. Saint

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/1486

CPC classification number: A61B5/14532 ,  A61B5/14503 ,  A61B5/683 ,  A61B5/6833 ,  A61B5/0004 ,  A61B5/0015 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/6849 ,  A61B2560/045

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

公开(公告)号：US11656195B2

公开(公告)日：2023-05-23

申请号：US16402101

申请日：2019-05-02

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC: G01N27/327 ,  A61B5/145 ,  A61B5/1495

CPC classification number: G01N27/3274 ,  A61B5/1495 ,  A61B5/14532 ,  A61B2560/0223

Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US11331022B2

公开(公告)日：2022-05-17

申请号：US17349755

申请日：2021-06-16

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart ,  John Stanley Hayes

IPC: G08B21/20 ,  A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

公开(公告)号：US20210393877A1

公开(公告)日：2021-12-23

申请号：US17464547

申请日：2021-09-01

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart ,  John Stanley Hayes

IPC: A61M5/172 ,  A61M15/00 ,  A61M35/00 ,  A61M5/20 ,  G16H20/17 ,  A61M5/142 ,  A61M11/00 ,  A61B5/145 ,  G16H40/63

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.