公开(公告)号：US11654023B2

公开(公告)日：2023-05-23

申请号：US16521226

申请日：2019-07-24

Applicant: Edwards Lifesciences Corporation

Inventor： Shahram Zamani ,  Michael Bukin ,  Sandip Vasant Pawar

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/2463 ,  A61F2220/0075 ,  A61F2250/0028 ,  A61F2250/0069

Abstract: A prosthetic heart valve includes a frame that is radially collapsible and expandable between a collapsed configuration and an expanded configuration, and defines a longitudinal axis. A leaflet structure situated within the frame, and a sealing member is disposed around the frame. The sealing member can include a first portion extending circumferentially around a portion of the frame, the first portion being configured to resiliently stretch in a direction along the longitudinal axis between a first state corresponding to the expanded configuration of the frame and a second state corresponding to the collapsed configuration of the frame. The sealing member can include a second portion extending circumferentially around a portion of the frame, the second portion being configured to resiliently stretch in a circumferential direction between a first state corresponding to the collapsed configuration of the frame and a second state corresponding to the expanded configuration of the frame.

公开(公告)号：US20220023038A1

公开(公告)日：2022-01-27

申请号：US17492408

申请日：2021-10-01

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolay Gurovich ,  Michael Bukin ,  Alexey Tsypenyuk ,  Elena Sherman ,  Dikla Kersh ,  Boaz Manash ,  Liron Tayeb ,  Ziv Yohanan ,  Alexander Barash ,  Yair A. Neumann ,  Tomer Saar

IPC: A61F2/24

Abstract: A prosthetic valve has an annular frame including a plurality of strut members that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. A leaflet structure is situated at least partially within the frame. The leaflet structure includes a plurality of leaflets, each leaflet having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form a commissure. The commissure tab portions of each leaflet are folded to form a plurality of layers positioned on the inside of the frame. A reinforcement member is positioned between the layers of each commissure tab portion.

公开(公告)号：US20210275303A1

公开(公告)日：2021-09-09

申请号：US17327575

申请日：2021-05-21

Applicant: Edwards Lifesciences Corporation

Inventor： Evan T. Schwartz ,  Sean Chow ,  Sandip Vasant Pawar ,  Darshin S. Patel ,  Chambory Chhe ,  Arpit Laddha ,  Ngoc Huong Thi Nguyen ,  Waina Michelle Chu ,  Yuanlong Du ,  Michael Bukin ,  Boaz Manash ,  Sara Tzadok (formerly Haivatov) ,  Tamir S. Levi

IPC: A61F2/24

Abstract: A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.

公开(公告)号：US20180133000A1

公开(公告)日：2018-05-17

申请号：US15809915

申请日：2017-11-10

Applicant: Edwards Lifesciences Corporation

Inventor： Taylor Jacob Scheinblum ,  Mindy Lee Ann Black ,  Tamir S. Levi ,  Evan T. Schwartz ,  Waina Michelle Chu ,  Linda Thai ,  Hanoch Cohen-Tzemach ,  Michael Bukin

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2403 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2433 ,  A61F2/2454 ,  A61F2/95 ,  A61F2002/9522 ,  B25B27/02

Abstract: Embodiments are provided of an assembly having a prosthetic valve, the prosthetic valve having a radially expandable and compressible annular frame, and a crimping accessory device, and methods for using the assembly in compressing the prosthetic valve. The frame includes an outer surface and an inner surface. A leaflet assembly is supported inside the annular frame. The leaflet assembly includes a plurality of leaflets, each having an inner surface and an outer surface. The crimping accessory device has a plurality of axially-extending fingers. At least a first finger of the plurality of fingers is disposed between the outer surface of a first leaflet of the plurality of leaflets, and at least a second finger of the plurality of fingers is disposed radially-inwardly of the inner surface of the first leaflet.

公开(公告)号：US20180021127A1

公开(公告)日：2018-01-25

申请号：US15697740

申请日：2017-09-07

Applicant: Edwards Lifesciences Corporation

Inventor： Ziv Yohanan ,  Tamir S. Levi ,  Netanel Benichou ,  Michael Bukin ,  Nikolay Gurovich ,  Elena Sherman

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2230/0054 ,  A61F2250/0036 ,  A61F2250/0039

Abstract: A prosthetic heart valve can comprise a radially collapsible and expandable annular frame and a leaflet structure comprising a plurality of leaflets mounted within the frame. The frame can have commissure attachment portions that are configured to support the commissures of the leaflets in unique ways. For example, commissure attachment portions can include at least two struts defining a gap therebetween. Additionaly, angularly-spaced commissure attachment portions can comprise inner struts and outer struts. Adjacent side portions of leaflets can extend through a gap between the inner struts of a corresponding commissure attachment portion. Further features and arrangements are also possible.

公开(公告)号：US20160045307A1

公开(公告)日：2016-02-18

申请号：US14922057

申请日：2015-10-23

Applicant: Edwards Lifesciences Corporation

Inventor： Ziv Yohanan ,  Tamir S. Levi ,  Netanel Benichou ,  Michael Bukin ,  Nikolay Gurovich ,  Elena Sherman

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2230/0054 ,  A61F2250/0036 ,  A61F2250/0039

Abstract: A prosthetic heart valve according to the present disclosure comprises a radially collapsible and expandable annular frame and a leaflet structure comprising a plurality of leaflets mounted within the frame. The frame in particular embodiments can have commissure attachment portions that are configured to support the commissures of the leaflets at locations spaced radially inwardly toward the longitudinal flow axis of the prosthetic valve relative to the frame portions circumscribing the moveable portions of the leaflets. When the leaflets open under pressure of blood flowing through the prosthetic valve, the moveable portions of the leaflets are retained at positions spaced inwardly from the inner surface of the frame to protect against abrasion of the leaflets.

公开(公告)号：US20250114198A1

公开(公告)日：2025-04-10

申请号：US18987648

申请日：2024-12-19

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Shahram Zamani ,  Michael Bukin ,  Sandip Vasant Pawar

IPC: A61F2/24 ,  A61F2/07

Abstract: A prosthetic heart valve includes a frame with a plurality of strut members, the frame being radially collapsible to a collapsed configuration and radially expandable to an expanded configuration, the frame having an inflow end and an outflow end, and defining a longitudinal axis. A leaflet structure is coupled to the frame and configured to regulate blood flow through the frame. A fabric sealing member is disposed around the frame, the sealing member being resiliently stretchable between a first state corresponding to the radially expanded configuration of the frame and a second state corresponding to the radially collapsed configuration of the frame. The sealing member has two ends, and the two ends are secured together by a seam.

公开(公告)号：US20250064584A1

公开(公告)日：2025-02-27

申请号：US18942285

申请日：2024-11-08

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael Bukin ,  Nikolai Gurovich ,  Elena Sherman ,  Anatoly Dvorsky ,  Giolnara Pinhas

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a radially expandable and compressible annular frame, a valvular structure, and a commissure cover. The frame can include a plurality of struts defining the annular frame, and a plurality of commissure support structures each defining a commissure opening positioned along a circumference of the annular frame. The valvular structure can be mounted within the frame, the valvular structure including a plurality of commissures each extending radially through a respective commissure opening to attach the valvular structure to the frame, each commissure having an outflow edge that extends from a radial outer surface of the frame. The commissure cover can be disposed at least partially over the outflow edge of the commissure and can define a ramped surface that extends from the radial outer surface of the frame to a radial outer surface of the commissure.

公开(公告)号：US12232956B2

公开(公告)日：2025-02-25

申请号：US18195288

申请日：2023-05-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Tamir S. Levi ,  Shahram Zamani ,  Michael Bukin ,  Ziv Yohanan ,  Noam Nir ,  Tyler Dale O'Dell ,  Elena Sherman

IPC: A61F2/24

Abstract: A method of assembling a valvular structure can include folding an upper tab of a first leaflet onto a lower tab of the first leaflet, disposing a first end of a reinforcing member on the upper tab, disposing a commissure member adjacent the lower tab, and coupling the first end of the reinforcing member, the tabs of the first leaflet, and the commissure member to one another. The method can further include folding an upper tab of a second leaflet onto a lower tab of the second leaflet, disposing the second leaflet adjacent the first leaflet such that the commissure member is positioned between the lower tabs, disposing a second end of the reinforcing member on the upper tab of the second leaflet, and coupling the reinforcing member, the upper and lower tabs of the second leaflet, and the commissure member to one another to form a commissure.

公开(公告)号：US12186185B2

公开(公告)日：2025-01-07

申请号：US17863195

申请日：2022-07-12

Applicant: Edwards Lifesciences Corporation

Inventor： Dikla Kersh ,  Michael Bukin ,  Tamir S. Levi ,  Noam Nir

IPC: A61F2/24

Abstract: A prosthetic valve assembly includes a radially expandable and compressible annular frame. The frame includes a plurality of interconnected struts, which include a plurality of inner struts and a plurality of outer struts. The inner struts overlap adjacent outer struts at a plurality of pivot joints. Radial expansion or compression of the annular frame causes the inner struts to pivot relative to the outer struts at the pivot joints. The assembly also includes a valvular structure having a plurality of leaflets, each leaflet having a cusp edge portion. The assembly further includes one or more leaflet-supporting cords, each having a plurality of anchoring portions and a plurality of suspended portions, each suspended portion extending between two adjacent anchoring portions. The anchoring portions are affixed to respective anchoring features of the frame adjacent the pivot joints. The cusp edge portions of the leaflets are connected to the suspended portions.