Automated inline preparation and degassing of volatile samples for inline analysis

    公开(公告)号:US11315776B2

    公开(公告)日:2022-04-26

    申请号:US17028115

    申请日:2020-09-22

    IPC分类号: G01N1/28 H01J49/04

    摘要: An analysis system includes a degassing cell, at least one first valve, and at least one second valve. The at least one first valve is fluidly coupled with a top of the degassing cell, the at least one first valve configured selectably connect the degassing cell to a displacement gas flow and to a vacuum source. The at least one second valve is fluidly connected with a lateral side of the degassing cell and separately fluidly connected with a bottom of the degassing cell. The at least one second valve is selectably coupled with any of a source of a sample-carrying fluid, a transfer line configured to deliver a sample to an analysis device, or a waste output.

    SYSTEMS AND METHODS FOR INLINE, DUAL-STAGE SAMPLE DILUTION

    公开(公告)号:US20210121873A1

    公开(公告)日:2021-04-29

    申请号:US17094246

    申请日:2020-11-10

    摘要: Sample preparation systems and methods are described having pump control, valve configurations, and control logic that facilitate automatic, inline preparation dilutions of a sample according to at least two dilution operating modes. A system embodiment includes, but is not limited to a first pump configured to drive a carrier fluid; a second pump configured to drive a diluent; and a plurality of selection valves fluidically coupled with the first pump and the second pump, the plurality of selection valves being configured to direct fluid flows from the first pump and the second pump according to at least two modes of operation to provide a single-stage sample dilution according to a first operating mode and to provide a dual-stage sample dilution according to a second operating mode.

    Peristaltic pump
    35.
    发明授权

    公开(公告)号:US10830227B2

    公开(公告)日:2020-11-10

    申请号:US16429741

    申请日:2019-06-03

    IPC分类号: F04B43/12 A61M5/142

    摘要: A peristaltic pump includes a rotating member operably coupled to a drive. The rotating member includes a plurality of rollers arranged in a circular configuration. A guide member defines a channel configured to direct a peristaltic tube around the rotating member so that the peristaltic tube interfaces with the plurality of rollers. The peristaltic tube is pressed against the plurality of rollers by a retaining shoe. The retaining shoe contains surface irregularities configured to restrict movement of the peristaltic tube. A keeper braces the restraining shoe against the peristaltic tube. The rotating rollers compressing the peristaltic tube against the retaining shoe as the rotating member rotates results in a peristaltic action that produces a nearly pulse free linear flow.

    System for humidifying gas streams
    36.
    发明授权

    公开(公告)号:US10746420B1

    公开(公告)日:2020-08-18

    申请号:US16371888

    申请日:2019-04-01

    摘要: In accordance with embodiments of this disclosure, a gas humidifier system includes a reservoir of liquid with at least one selectively permeable tube at least partially submerged within the liquid. A gas stream may be fed into the selectively permeable tube that passes through the liquid reservoir. The selectively permeable tube may be substantially impermeable to the gas flowing therethrough but permeable to vapor (e.g., water vapor) entering the selectively permeable tube from the liquid. Thus, vapor from the liquid reservoir can enter the selectively permeable tube and humidify the gas flowing therethrough.

    Rapid flow-through sampling system with triggered introduction to nebulizer

    公开(公告)号:US10741374B1

    公开(公告)日:2020-08-11

    申请号:US16415284

    申请日:2019-05-17

    摘要: Systems and methods are described for rapid throughput of samples from a plurality of sample sources to a nebulizer for analysis, such as a sample analysis via ICP-MS. A system embodiment can include, but is not limited to, a valve in fluid communication with a fluid transfer line to receive a plurality of samples from a plurality of sample sources from an autosampler unit and direct the sample into a valve channel; a first pump to draw sample into the valve channel, a sensor positioned adjacent a nebulizer to detect respective samples of the plurality of samples and generate one or more signals in response thereto; a second pump to push the sample from the valve channel to the nebulizer; and a controller configured to coordinate operation of the first pump, the second pump, and the valve based at least on the one or more signals.

    Treated nebulizer tip and spray chamber

    公开(公告)号:US10661283B1

    公开(公告)日:2020-05-26

    申请号:US15187082

    申请日:2016-06-20

    摘要: A system can include a nebulizer having a tip and a spray chamber configured to be in fluid communication with the nebulizer. The tip of the nebulizer and/or an interior of the spray chamber can have a treated surface. The nebulizer and/or the spray chamber can be treated using a physical abrasion technique, chemically etched, and so forth. In some embodiments, treated surfaces of the nebulizer and the spray chamber can be proximate to one another. The spray chamber can include a drain ridge, which can project into an interior of the spray chamber, be depressed away from an interior of the spray chamber, and/or include a treated surface. The spray chamber can also include an output port having a treated surface. In some embodiments, the output port can include an additional port so that rinse liquid can flow through the spray chamber (e.g., continuously and/or intermittently).

    Ultraclean autosampler with syringe delivery for mass spectrometry

    公开(公告)号:US10465853B2

    公开(公告)日:2019-11-05

    申请号:US15620092

    申请日:2017-06-12

    摘要: A system can include a valve assembly including a first valve and a second valve in fluid communication with the first valve. The valve assembly can be configured to deliver one or more of a sample, a chemical (e.g., an acid, a base, an organic chemical, etc.), and a standard via flow of a working fluid facilitated by one or more syringe pumps. Further, the one or more of the sample, the chemical, and the standard can maintain a physical separation from the one or more syringe pumps during delivery of the one or more of the sample, the chemical, and the standard.

    DUAL SPRAY CHAMBER
    40.
    发明申请
    DUAL SPRAY CHAMBER 审中-公开

    公开(公告)号:US20190293522A1

    公开(公告)日:2019-09-26

    申请号:US16293172

    申请日:2019-03-05

    摘要: A dual spray chamber apparatus is described. In one or more implementations, the dual spray chamber apparatus includes a first cyclonic spray chamber for receiving an aerosol and conditioning the aerosol to separate a first conditioned portion of the aerosol from a second portion of the aerosol. The first cyclonic spray chamber defines a first chamber interior and comprises an input port in fluid communication with the first chamber interior. The dual spray chamber apparatus also includes a second spray chamber coupled with the first cyclonic spray chamber for receiving the first conditioned portion of the aerosol and further conditioning the first conditioned portion of the aerosol. The second spray chamber defines a second chamber interior and comprises an output port for expelling a first further conditioned portion of the first conditioned portion of the aerosol from the second chamber interior.