公开(公告)号：US08366643B2

公开(公告)日：2013-02-05

申请号：US12559448

申请日：2009-09-14

申请人： Mark E. Deem ,  Hanson S. Gifford, III ,  Douglas S. Sutton

发明人： Mark E. Deem ,  Hanson S. Gifford, III ,  Douglas S. Sutton

IPC分类号： A61H1/00

CPC分类号： A61N7/00 ,  A61B2017/00747 ,  A61B2017/22008 ,  A61K9/0009 ,  A61K41/0028 ,  A61M37/0092 ,  A61M2037/003 ,  A61N1/0412 ,  A61N1/0492 ,  A61N1/327 ,  A61N2007/0008 ,  A61N2007/0039

摘要： An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing agents, wherein disruption of subcutaneous tissues and subcutaneous cavitational bioeffects are produced by ultrasound waves having a power that will not produce tissue cavitation in the absence of the enhancing agents. The apparatus and method of use is useful for treatment of subcutaneous abnormalities including cellulite, lipomas, and tumors.

摘要翻译： 公开了一种在低声压超声波范围内使用声波处理皮下组织的装置和方法。 该方法包括注射增强剂，其中通过具有在不存在增强剂的情况下不产生组织空泡的能力的超声波产生皮下组织的破坏和皮下空泡生物效应。 该装置和使用方法可用于治疗包括脂肪团，脂肪瘤和肿瘤在内的皮下异常。

公开(公告)号：US08070670B2

公开(公告)日：2011-12-06

申请号：US11560776

申请日：2006-11-16

申请人： Mark E. Deem ,  Hanson S. Gifford, III ,  Bernard Andreas ,  Sunmi Chew ,  Ron French ,  Doug Sutton

发明人： Mark E. Deem ,  Hanson S. Gifford, III ,  Bernard Andreas ,  Sunmi Chew ,  Ron French ,  Doug Sutton

IPC分类号： A61F2/02

CPC分类号： A61B17/12013 ,  A61B17/12 ,  A61B17/12022 ,  A61B17/12099 ,  A61B17/12186 ,  A61B17/3478 ,  A61B2017/00805 ,  A61B2017/00827 ,  A61B2017/00876 ,  A61B2017/1205 ,  A61N2/02 ,  A61N2/06

摘要： Devices and methods for augmenting or otherwise enhancing closure of body lumens comprise magnetic or magnetizable components or particles which are implanted in the wall of the lumen. The magnet fields exerted by the components or particles act to close the body lumen with a desired force.

公开(公告)号：US08038673B2

公开(公告)日：2011-10-18

申请号：US11472631

申请日：2006-06-21

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

公开(公告)号：US20110226238A1

公开(公告)日：2011-09-22

申请号：US12885199

申请日：2010-09-17

申请人： Michael Barrett ,  Michael Hendricksen ,  Alan R. Rapacki ,  Ronald R. Hundertmark ,  Jeffrey J. Dolin ,  Robert M. George ,  Antony J. Fields ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Ronald French ,  Douglas Sutton

发明人： Michael Barrett ,  Michael Hendricksen ,  Alan R. Rapacki ,  Ronald R. Hundertmark ,  Jeffrey J. Dolin ,  Robert M. George ,  Antony J. Fields ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Ronald French ,  Douglas Sutton

IPC分类号： A61M16/20

CPC分类号： A61B17/12022 ,  A61B17/12104 ,  A61B17/12172 ,  A61F2/2412 ,  A61F2002/043

摘要： Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.

摘要翻译： 公开了用于调节流入和流出患者肺部区域的流体的方法和装置，例如在呼吸过程中实现期望的流体流动到肺部区域，和/或诱导一个或多个肺部区域的塌陷。 根据示例性程序，确定的肺部区域被靶向用于治疗。 然后将目标肺区域支气管分离，以通过一个或多个将空气送入目标肺部区域的支气管通路来调节进入和/或离开目标肺区域的气流。

公开(公告)号：US07938852B2

公开(公告)日：2011-05-10

申请号：US12040598

申请日：2008-02-29

申请人： Bernard Andreas ,  Ron French ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Allan Will

发明人： Bernard Andreas ,  Ron French ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Allan Will

IPC分类号： A61F2/06

CPC分类号： A61F2/95 ,  A61B1/00151 ,  A61F2/966 ,  A61F2002/9517 ,  Y10S623/903

摘要： Blood vessels and other body lumens are expanded using an evertible braided prosthesis. The braided prosthesis is delivered to the blood vessel in a radially collapsed configuration. A leading edge of the braided prosthesis is then everted so that it expands as it is advanced through the blood vessel. Optionally, the prosthesis can be provided with a biologically active substance in order to inhibit hyperplasia or have other desired biological effects.

摘要翻译： 使用可逆的编织假体扩张血管和其他体腔。 编织的假体以径向收缩的构型输送到血管。 然后，编织假体的前缘被转动，使得它在其通过血管前进时膨胀。 任选地，假体可以具有生物活性物质，以便抑制增生或具有其它所需的生物效应。

公开(公告)号：US20090275899A1

公开(公告)日：2009-11-05

申请号：US12467240

申请日：2009-05-15

申请人： Mark E. Deem ,  Hanson S. Gifford, III ,  Douglas Sutton

发明人： Mark E. Deem ,  Hanson S. Gifford, III ,  Douglas Sutton

IPC分类号： A61M5/32 ,  A61B18/18

CPC分类号： A61N7/00 ,  A61B2017/00747 ,  A61B2017/22008 ,  A61K9/0009 ,  A61K41/0028 ,  A61M37/0092 ,  A61M2037/003 ,  A61N1/0412 ,  A61N1/0492 ,  A61N1/327 ,  A61N2007/0008 ,  A61N2007/0039

摘要： An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing agents, wherein disruption of subcutaneous tissues and subcutaneous cavitational bioeffects are produced by ultrasound waves having a power that will not produce tissue cavitation in the absence of the enhancing agents. The apparatus and method of use is useful for treatment of subcutaneous abnormalities including cellulite, lipomas, and tumors.

摘要翻译： 公开了一种在低声压超声波范围内使用声波处理皮下组织的装置和方法。 该方法包括注射增强剂，其中通过具有在不存在增强剂的情况下不产生组织空泡的能力的超声波产生皮下组织的破坏和皮下空泡生物效应。 该装置和使用方法可用于治疗包括脂肪团，脂肪瘤和肿瘤在内的皮下异常。

公开(公告)号：US20090088832A1

公开(公告)日：2009-04-02

申请号：US11938730

申请日：2007-11-12

申请人： Sunmi Chew ,  Bernard Andreas ,  Hanson S. Gifford, III ,  Ron French ,  Mark E. Deem ,  Allan Will

发明人： Sunmi Chew ,  Bernard Andreas ,  Hanson S. Gifford, III ,  Ron French ,  Mark E. Deem ,  Allan Will

IPC分类号： A61F2/06

CPC分类号： A61F2/88 ,  A61F2/0095 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2/95 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/91533 ,  A61F2002/91541 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/91591 ,  A61F2002/9583 ,  A61F2210/0004 ,  A61F2210/0033 ,  A61F2210/0042 ,  A61F2250/0071

摘要： Blood vessels and other body lumens are stented using multiple, discrete stent structures, or continuous coiled or mesh stent structures. Stent structures may be a balloon expandable or self-expanding and are delivered by a delivery catheter which is repositioned to spaced-apart delivery sites. By coating the stents with particular biologically active substances, hyperplasia within and between the implanted stents can be inhibited. An exemplary delivery catheter comprises a catheter body having a deployment mechanism for deploying one or more stents of selectable length into the vessel.

摘要翻译： 使用多个分立的支架结构或连续卷曲或网状支架结构来支架血管和其他体腔。 支架结构可以是球囊可扩张的或自膨胀的，并且由递送导管递送，该输送导管重新定位成间隔的递送部位。 通过用特定生物活性物质涂覆支架，可以抑制植入支架内和植入支架之间的增生。 示例性递送导管包括具有用于将一个或多个可选择长度的支架部署到血管中的展开机构的导管主体。

公开(公告)号：US07288099B2

公开(公告)日：2007-10-30

申请号：US10313394

申请日：2002-12-05

申请人： Mark E. Deem ,  Douglas S. Sutton ,  Hanson S. Gifford, III ,  Bernard H. Andreas ,  Ronald G French

发明人： Mark E. Deem ,  Douglas S. Sutton ,  Hanson S. Gifford, III ,  Bernard H. Andreas ,  Ronald G French

IPC分类号： A61B17/08

CPC分类号： A61B17/1114 ,  A61B17/00234 ,  A61B17/064 ,  A61B17/0644 ,  A61B17/122 ,  A61B2017/00557 ,  A61B2017/306 ,  A61B2090/395 ,  A61F5/0083 ,  A61F5/0086

摘要： Various obesity treatment tools and methods are described herein, as well as treatments for other gastric-related diseases, e.g., GERD. Treatment includes reducing the size of the stomach pouch to limit the caloric intake as well as to provide an earlier feeling of satiety. This may be done by creating a smaller gastric pouch within the stomach directly from the interior of the stomach itself. The smaller pouches may be made through the use of individual anchoring devices, rotating probes, or volume reduction devices. A pyloroplasty procedure may also be performed to render the pyloric sphincter incompetent. A gastric bypass procedure may additionally be performed using a traumatic magnetic anastomoses devices so that sugars and fats are passed directly to the bowel while bypassing the stomach. Many of these procedures may be done in a variety of combinations. Treatment may create enforced behavioral modifications by discouraging the ingestion of high-caloric foods.

摘要翻译： 本文描述了各种肥胖治疗工具和方法，以及用于其它胃相关疾病例如GERD的治疗。 治疗包括减小胃袋的尺寸以限制热量摄入以及提供较早的饱腹感。 这可以通过在胃内部直接从胃内部产生较小的胃袋来完成。 较小的小袋可以通过使用单独的锚定装置，旋转探针或体积减小装置来制造。 还可以进行幽门成形术以使幽门括约肌无能力。 另外可以使用创伤性磁性吻合装置进行胃旁路手术，使得糖和脂肪在绕过胃时直接通过肠。 这些程序中的许多可以以各种组合进行。 治疗可能会通过阻止摄入高热量食物而产生强制行为改变。

公开(公告)号：US08474460B2

公开(公告)日：2013-07-02

申请号：US12885199

申请日：2010-09-17

申请人： Michael Barrett ,  Michael Hendricksen ,  Alan R. Rapacki ,  Ronald R. Hundertmark ,  Jeffrey J. Dolin ,  Robert M. George ,  Antony J. Fields ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Ronald French ,  Douglas Sutton

发明人： Michael Barrett ,  Michael Hendricksen ,  Alan R. Rapacki ,  Ronald R. Hundertmark ,  Jeffrey J. Dolin ,  Robert M. George ,  Antony J. Fields ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Ronald French ,  Douglas Sutton

IPC分类号： A62B9/02

CPC分类号： A61B17/12022 ,  A61B17/12104 ,  A61B17/12172 ,  A61F2/2412 ,  A61F2002/043

摘要： Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.

摘要翻译： 公开了用于调节流入和流出患者肺部区域的流体的方法和装置，例如在呼吸过程中实现期望的流体流动到肺部区域，和/或诱导一个或多个肺部区域的塌陷。 根据示例性程序，确定的肺部区域被靶向用于治疗。 然后将目标肺区域支气管分离，以通过一个或多个将空气送入目标肺部区域的支气管通路来调节进入和/或离开目标肺区域的气流。

公开(公告)号：US08348867B2

公开(公告)日：2013-01-08

申请号：US12467234

申请日：2009-05-15

申请人： Mark E. Deem ,  Hanson S. Gifford, III ,  Douglas Sutton

发明人： Mark E. Deem ,  Hanson S. Gifford, III ,  Douglas Sutton

IPC分类号： A61H1/00

CPC分类号： A61N7/00 ,  A61B2017/00747 ,  A61B2017/22008 ,  A61K9/0009 ,  A61K41/0028 ,  A61M37/0092 ,  A61M2037/003 ,  A61N1/0412 ,  A61N1/0492 ,  A61N1/327 ,  A61N2007/0008 ,  A61N2007/0039

摘要： An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing agents, wherein disruption of subcutaneous tissues and subcutaneous cavitational bioeffects are produced by ultrasound waves having a power that will not produce tissue cavitation in the absence of the enhancing agents. The apparatus and method of use is useful for treatment of subcutaneous abnormalities including cellulite, lipomas, and tumors.

摘要翻译： 公开了一种在低声压超声波范围内使用声波处理皮下组织的装置和方法。 该方法包括注射增强剂，其中通过具有在不存在增强剂的情况下不产生组织空泡的能力的超声波产生皮下组织的破坏和皮下空泡生物效应。 该装置和使用方法可用于治疗包括脂肪团，脂肪瘤和肿瘤在内的皮下异常。