公开(公告)号：US20220018755A1

公开(公告)日：2022-01-20

申请号：US17413706

申请日：2019-01-13

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Viktor Shkolnikov ,  Diane R. Hammerstad

IPC: G01N15/14 ,  G01N1/14

Abstract: A particle classification system may include a volume to contain a fluid having a suspended particle, electrodes proximate the volume to apply an electric field to rotate the suspended particle, a focused light source, a scattered light sensor to sense light from the focused light source that has scattered upon impinging the rotating suspended particle and a controller to classify the particle based at least in part upon signals from the scattered light sensor.

公开(公告)号：US10365226B2

公开(公告)日：2019-07-30

申请号：US15546936

申请日：2015-04-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Alexander Govyadinov ,  Charles M. Santori ,  Anita Rogacs ,  Diane R. Hammerstad ,  Manish Giri

IPC: G01N15/14 ,  G01N21/27 ,  G01N21/64 ,  G01N21/85 ,  G01V8/12 ,  B41J2/125 ,  B41J2/175 ,  B41J2/195

Abstract: Provided in one example is an apparatus, including a substrate supporting a microfluidic channel, a bubble jet inertial pump supported by the substrate adjacent the microfluidic channel to pump fluid through the microfluidic channel and an optical sensor on a first side of the microfluidic channel. A light emitter on a second side of the microfluidic channel is to pass light across the microfluidic channel to the optical sensor.

公开(公告)号：US12044613B2

公开(公告)日：2024-07-23

申请号：US17413706

申请日：2019-01-13

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Viktor Shkolnikov ,  Diane R. Hammerstad

IPC: G01N15/1434 ,  G01N15/00 ,  G01N15/1404

CPC classification number: G01N15/1434 ,  G01N2015/0053 ,  G01N2015/1422

Abstract: A particle classification system may include a volume to contain a fluid having a suspended particle, electrodes proximate the volume to apply an electric field to rotate the suspended particle, a focused light source, a scattered light sensor to sense light from the focused light source that has scattered upon impinging the rotating suspended particle and a controller to classify the particle based at least in part upon signals from the scattered light sensor.

公开(公告)号：US12025549B2

公开(公告)日：2024-07-02

申请号：US17414155

申请日：2019-05-13

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Viktor Shkolnikov ,  Alexander Govyadinov ,  Diane R. Hammerstad

IPC: G01N15/12 ,  B01L3/00 ,  B81B7/02 ,  G01N15/10 ,  G01N15/1031 ,  G01N33/543

CPC classification number: G01N15/12 ,  B01L3/502761 ,  B81B7/02 ,  G01N15/1023 ,  G01N15/1031 ,  G01N33/54386 ,  B01L2200/025 ,  B01L2200/0652 ,  B01L2200/0663 ,  B01L2300/0645 ,  B01L2300/0663 ,  B01L2300/0829 ,  B01L2300/14 ,  B01L2400/02 ,  B01L2400/0487 ,  G01N2015/1006 ,  G01N2015/1028

Abstract: A system includes a microchannel analysis region, a first fluid actuation device, a second fluid actuation device, a sensor, and a controller. The first fluid actuation device is at a first end of the microchannel analysis region. The second fluid actuation device is at a second end of the microchannel analysis region opposite to the first end. The sensor is within the microchannel analysis region between the first fluid actuation device and the second fluid actuation device. The sensor measures an impedance of a fluid within the microchannel analysis region. The controller activates the first fluid actuation device to generate a first pressure wave in the fluid and activates the second fluid actuation device to generate a second pressure wave in the fluid. The first pressure wave and the second pressure wave converge at the sensor.

公开(公告)号：US20210346885A1

公开(公告)日：2021-11-11

申请号：US17059650

申请日：2019-02-01

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Alexander Govyadinov ,  Viktor Shkolnikov ,  Diane R. Hammerstad

IPC: B01L3/00 ,  G01N15/00

Abstract: In one example in accordance with the present disclosure, a cellular analytic system is described. The cellular analytic system includes an analytic device. The analytic device includes a chamber to receive a cell to be analyzed. At least one lysing element agitates the cell and at least one sensor detects a change in the cell based on an agitation of the cell. The cellular analytic system also includes a controller to determine a rupture threshold of the cell based on parameters of the agitation when a cell membrane ruptures.

公开(公告)号：US20210238537A1

公开(公告)日：2021-08-05

申请号：US17049406

申请日：2018-08-10

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander Govyadinov ,  Diane R. Hammerstad ,  Viktor Shkolnikov

IPC: C12M1/00 ,  C12M1/36 ,  C12N1/06

Abstract: In one example in accordance with the present disclosure, a conductivity-based lysis monitor is described. The lysis monitoring device includes a lysing chamber to receive a cell to be lysed and at least one lysing device to rupture a cell membrane. At least one pair of electrodes are disposed in the lysing chamber to detect a level of conductivity in the lysing chamber. A controller of the device determines when the cell membrane has ruptured based on detected levels of conductivity in the lysing chamber.

公开(公告)号：US20200224145A1

公开(公告)日：2020-07-16

申请号：US16605193

申请日：2017-09-23

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Viktor Shkolnikov ,  Diane R. Hammerstad ,  Michael W. Cumbie

IPC: C12M1/42 ,  C12M1/36 ,  C12N13/00 ,  C12N15/87 ,  C12M1/26

Abstract: An electroporation system may include a well plate, a dispenser and a dispenser-well positioning system. The well plate may include wells, each of the wells including an interior, a first electrode adjacent the interior and a second electrode adjacent the interior and spaced from the first electrode. The first electrode and the second electrode are to apply an electrostatic field across the well. The dispenser is to dispense a cell having a diameter into each of the wells. The dispenser-well positioning system is to align each well and the dispenser such that the dispenser dispenses the cell into each well at a location spaced from the first electrode and the second electrode by a distance of at least 5 times the diameter of the cell.

公开(公告)号：US10232618B2

公开(公告)日：2019-03-19

申请号：US15865864

申请日：2018-01-09

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Chien-Hua Chen ,  Michael W. Cumbie ,  Diane R. Hammerstad

IPC: B41J2/14

Abstract: In one example, a fluid flow structure includes a fluid dispensing micro device embedded in a molding having a channel therein through which fluid may flow directly to the device. The device contains multiple fluid ejectors and multiple fluid chambers each near an ejector. Each chamber has an inlet through which fluid from the channel may enter the chamber and an outlet through which fluid may be ejected from the chamber. A perimeter of the channel surrounds the inlets but is otherwise unconstrained in size by the size of the device.

公开(公告)号：US09898235B2

公开(公告)日：2018-02-20

申请号：US14785448

申请日：2013-07-24

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Shinoj Bhaskaran ,  Ruby Tomar ,  Puneet Kumar Arora ,  Diane R. Hammerstad

IPC: G06F3/12 ,  H04N1/00 ,  G06K15/02

CPC classification number: G06F3/1239 ,  G06F3/1219 ,  G06F3/1287 ,  G06K15/1809

Abstract: In one example of the disclosure, account data that is indicative of marking agent credits attributed to a printer is stored. The printer is a printer connected to a supply of marking agent. A marking agent credit is to authorize consumption of a credit amount of marking agent from the supply according to a subscription. A print job is received from a sponsor computing device. The account data is adjusted to add credits in an adjustment amount that is a function of marking agent consumption to print the job. The job is sent to the printer for printing.

公开(公告)号：US20170028725A1

公开(公告)日：2017-02-02

申请号：US15303316

申请日：2014-04-22

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Chien-Hua CHEN ,  Michael W. Cumbie ,  Diane R. Hammerstad

IPC: B41J2/14

CPC classification number: B41J2/1433 ,  B41J2/1404 ,  B41J2002/14419 ,  B41J2202/20

Abstract: In one example, a fluid flow structure includes a fluid dispensing micro device embedded in a molding having a channel therein through which fluid may flow directly to the device. The device contains multiple fluid ejectors and multiple fluid chambers each near an ejector. Each chamber has an inlet through which fluid from the channel may enter the chamber and an outlet through which fluid may be ejected from the chamber. A perimeter of the channel surrounds the inlets but is otherwise unconstrained in size by the size of the device.

Abstract translation: 在一个示例中，流体流动结构包括嵌入在其中具有通道的模制件中的流体分配微型装置，流体可以通过该通道直接流向装置。 该装置包含多个流体喷射器和多个流体室，每个流体喷射器各自靠近喷射器。 每个室具有一个入口，来自该通道的流体可以通过该入口进入该室，一个出口，流体可通过该出口从该室排出。 通道的周边围绕入口，但是在尺寸上不受约束的尺寸。