公开(公告)号：US20090194693A1

公开(公告)日：2009-08-06

申请号：US12301642

申请日：2007-05-14

申请人： Derk Jan Wilfred Klunder ,  Aleksey Kolesnychenko

发明人： Derk Jan Wilfred Klunder ,  Aleksey Kolesnychenko

IPC分类号： G01N21/64 ,  G01N21/76

CPC分类号： G01N21/6456 ,  G01N21/6428 ,  G01N21/76

摘要： An imaging apparatus is disclosed for combined temperature and luminescence spatial imaging of an object (1), such as a bio-array for detection of biological molecules. Light (5) is separated into a first (10) and a second (20) optical path, where the first optical path (10) guides infrared (IR), and the second optical path (20) guides luminescence light, preferably fluorescence light, from the object (1). Image intensifying means (30) converts infrared light (10a) in the first optical path into intensified light (10b), preferably visible light. Photo detection means (100) are arranged for spatial imaging of the object (1), the photo detection means being arranged for alternately receiving light from the first (10) and the second (20) optical path. Processing means (200) are capable of combining a temperature image (11) with a luminescence image (21) so as to obtain a combined image (25) of the object with a direct spatial correspondence between the two images. For bio-arrays this provides many advantages in relation to combined imaging of an array, whereupon numerous probe molecules are located.

摘要翻译： 公开了用于物体（1）的组合温度和发光空间成像的成像装置，例如用于检测生物分子的生物阵列。 光（5）被分离为第一光路（10）和第二光路（20），其中第一光路（10）引导红外（IR），第二光路（20）引导发光，优选荧光 ，从对象（1）。 图像增强装置（30）将第一光路中的红外光（10a）转换成强光（10b），优选可见光。 照片检测装置（100）布置成用于物体（1）的空间成像，光检测装置被布置成交替地接收来自第一光（10）和第（20）光路的光。 处理装置（200）能够将温度图像（11）与发光图像（21）组合，从而以两个图像之间的直接空间对应来获得对象的组合图像（25）。 对于生物阵列，这提供了与阵列的组合成像相关的许多优点，因此存在许多探针分子。

公开(公告)号：US20060232756A1

公开(公告)日：2006-10-19

申请号：US11239480

申请日：2005-09-30

申请人： Joeri Lof ,  Antonius Theodorus Derksen ,  Christiaan Hoogendam ,  Aleksey Kolesnychenko ,  Erik Loopstra ,  Theodorus Modderman ,  Johannes Catharinus Mulkens ,  Roelof Aeilko Ritsema ,  Klaus Simon ,  Joannes De Smit ,  Alexander Straaijer ,  Bob Streefkerk ,  Helmar Santen ,  Sjoerd Nicolaas Donders

发明人： Joeri Lof ,  Antonius Theodorus Derksen ,  Christiaan Hoogendam ,  Aleksey Kolesnychenko ,  Erik Loopstra ,  Theodorus Modderman ,  Johannes Catharinus Mulkens ,  Roelof Aeilko Ritsema ,  Klaus Simon ,  Joannes De Smit ,  Alexander Straaijer ,  Bob Streefkerk ,  Helmar Santen ,  Sjoerd Nicolaas Donders

IPC分类号： G03B27/42

CPC分类号： G03F7/70341

摘要： In a lithographic projection apparatus, a structure surrounds a space between the projection system and a substrate table of the lithographic projection apparatus. Gas is used between the structure and the surface of the substrate to contain liquid in the space.

摘要翻译： 在光刻投影装置中，结构围绕投影系统与光刻投影装置的基板台之间的空间。 在结构和衬底的表面之间使用气体以在空间中容纳液体。

公开(公告)号：US20060180952A1

公开(公告)日：2006-08-17

申请号：US11155941

申请日：2005-02-17

申请人： Yvonne Kruijt-Stegeman ,  Henricus Janssen ,  Aleksey Kolesnychenko ,  Helmar Santen

发明人： Yvonne Kruijt-Stegeman ,  Henricus Janssen ,  Aleksey Kolesnychenko ,  Helmar Santen

IPC分类号： B29C59/02 ,  C23F1/00 ,  B28B11/08

CPC分类号： G03F7/0002 ,  B82Y10/00 ,  B82Y40/00 ,  C23F1/02 ,  Y10S977/887

摘要： An imprinting method is disclosed that includes applying an imprinting force to a template to cause the template to contact an imprintable medium on a target region of a first surface of a substrate to form an imprint in the medium, during application of the imprinting force, applying a compensating force to a second surface of the substrate which is opposite to the first surface so as to reduce deformation of the substrate caused by the application of the imprinting force, and separating the template from the imprinted medium.

摘要翻译： 公开了一种压印方法，其包括对模板施加压印力，以使得模板在施加压印力的同时在介质的第一表面的目标区域上接触可压印的介质以形成印记， 对基板的与第一表面相对的第二表面的补偿力，以减少由施加压印力引起的基板的变形，以及将模板与压印介质分离。

公开(公告)号：US20120033210A1

公开(公告)日：2012-02-09

申请号：US13273801

申请日：2011-10-14

申请人： Aleksey Kolesnychenko ,  Jorrit E. De Vries ,  Jozef C. M. Versleegers ,  Michiel De Jong ,  Theodoor B. J. Haddeman ,  Louis Stroucken

发明人： Aleksey Kolesnychenko ,  Jorrit E. De Vries ,  Jozef C. M. Versleegers ,  Michiel De Jong ,  Theodoor B. J. Haddeman ,  Louis Stroucken

IPC分类号： G01N1/10

CPC分类号： G01N21/6452

摘要： An optical detection system for monitoring real-time PCR reactions in a plurality of sample chambers with a plurality of optical units is provided. Due to a relative movement, the optical units are relative to the sample chambers, color multiplexing and space multiplexing are combined for optically detecting pathogens in a sample during the process of the PCR and delivering a quantitative result.

摘要翻译： 提供了一种用于在具有多个光学单元的多个样品室中监测实时PCR反应的光学检测系统。 由于相对运动，光学单元相对于样品室，彩色复用和空间复用被组合用于在PCR过程中光学检测样品中的病原体并递送定量结果。

公开(公告)号：US20090116125A1

公开(公告)日：2009-05-07

申请号：US12302049

申请日：2007-05-25

申请人： Aleksey Kolesnychenko ,  Sjoerd Stallinga ,  Hendrik Roelof Stapert

发明人： Aleksey Kolesnychenko ,  Sjoerd Stallinga ,  Hendrik Roelof Stapert

IPC分类号： G02B9/00 ,  G02B17/00 ,  G01J5/08

CPC分类号： G01J5/08 ,  G01J5/0037 ,  G01J5/0806 ,  G01J5/0809 ,  G01J5/0846 ,  G01J5/0862 ,  G01J5/089 ,  G01J5/602 ,  G01J2005/0077 ,  G01N2021/6478 ,  G02B27/42 ,  G02B27/4233

摘要： The present invention concerns a lens system. More specifically, it concerns a lens system comprising a first lens (3), a deflection element (5) and a second lens (6), wherein the deflection element (5) is arranged between the first lens (3) and the second lens (6). The deflection element comprises at least a first annular zone and a second annular zone, the annular zones being arranged in a concentric fashion and wherein the deflection angle of each annular zone is different from the deflection angle of every other annular zone. Furthermore, the present invention concerns a temperature analysis system comprising a lens system and the use of a temperature analysis system.

摘要翻译： 本发明涉及一种透镜系统。 更具体地，涉及一种包括第一透镜（3），偏转元件（5）和第二透镜（6）的透镜系统，其中偏转元件（5）布置在第一透镜（3）和第二透镜 （6）。 偏转元件至少包括第一环形区域和第二环形区域，环形区域以同心方式布置，并且其中每个环形区域的偏转角度与每隔一个环形区域的偏转角度不同。 此外，本发明涉及包括透镜系统和使用温度分析系统的温度分析系统。

公开(公告)号：US20090093064A1

公开(公告)日：2009-04-09

申请号：US12296713

申请日：2007-04-05

申请人： Aleksey Kolesnychenko

发明人： Aleksey Kolesnychenko

IPC分类号： G01N1/28 ,  B01J19/00 ,  G01N30/00

CPC分类号： G01N21/6428 ,  B01L3/502 ,  B01L2300/0681 ,  B01L2300/0861 ,  B01L2400/0481 ,  Y10T436/25

摘要： An improved flow-through device is provided wherein foam produced by the pumping of fluid in the device is kept outside the reaction chambers by way of a hydrophobic or hydrophilic porous membrane acting as an air trap membrane.

摘要翻译： 提供了一种改进的流通装置，其中通过泵送设备中的流体产生的泡沫通过用作空气阱膜的疏水或亲水多孔膜而保持在反应室外。

公开(公告)号：US20080303870A1

公开(公告)日：2008-12-11

申请号：US12158513

申请日：2006-12-19

申请人： Roy Gerardus Franciscus Antonius Verbeek ,  Richard Joseph Marinus Schroeders ,  Aleksey Kolesnychenko

发明人： Roy Gerardus Franciscus Antonius Verbeek ,  Richard Joseph Marinus Schroeders ,  Aleksey Kolesnychenko

IPC分类号： B41J2/05

CPC分类号： B41J3/28 ,  B01J19/0046 ,  B01J2219/0036 ,  B01J2219/00378 ,  B01J2219/00495 ,  B01J2219/00527 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00641 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00662 ,  B01J2219/00677 ,  B01J2219/00689 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01L3/0268 ,  B01L2300/0819 ,  B01L2300/1872 ,  B41J3/407

摘要： The invention provides an ink jet device for the positioning of a substance onto a substrate, the device comprising at least a print head comprising a nozzle provided to eject a droplet comprising the substance, the ink jet device further comprising at least one heating element arranged such that the substrate can be heated prior to, during and/or after the landing of a droplet on the substrate.

摘要翻译： 本发明提供了一种用于将物质定位到基底上的喷墨装置，该装置至少包括一个打印头，该打印头包括一个喷嘴，该喷嘴被设置成喷射包括该物质的液滴，喷墨装置还包括至少一个这样的加热元件 衬底可以在液滴在衬底上着落之前，期间和/或之后被加热。

公开(公告)号：US20060230959A1

公开(公告)日：2006-10-19

申请号：US11108904

申请日：2005-04-19

申请人： Peter Bartus Meijer ,  Aleksey Kolesnychenko

发明人： Peter Bartus Meijer ,  Aleksey Kolesnychenko

IPC分类号： B41G7/00

CPC分类号： G03F7/0002 ,  B82Y10/00 ,  B82Y40/00 ,  Y10S977/887

摘要： An imprint template configured to imprint an imprintable medium by an imprint lithography process is disclosed, the imprint template having a pattern with a pattern density corresponding to a volume of imprintable medium used to substantially fill pattern features per unit area of a contact face of the imprint template, wherein adjacent regions of the pattern on the imprint template contact face, each of which will provide different functionality once imprinted onto a substrate, have substantially the same pattern density, have differences in pattern density which are minimized, or differences in pattern density which are maintained below a maximum.

公开(公告)号：US20060144814A1

公开(公告)日：2006-07-06

申请号：US11025606

申请日：2004-12-30

申请人： Aleksey Kolesnychenko ,  Helmar Santen ,  Yvonne Kruijt-Stegeman ,  Peter Meijer

发明人： Aleksey Kolesnychenko ,  Helmar Santen ,  Yvonne Kruijt-Stegeman ,  Peter Meijer

IPC分类号： C23F1/00 ,  B44C1/22 ,  C03C15/00 ,  B29D11/00

CPC分类号： G03F7/0002 ,  B82Y10/00 ,  B82Y40/00

摘要： An imprinting method is disclosed, which in an embodiment, involves contacting an imprintable medium on a substrate with a template to form an imprint in the medium comprising a pattern feature and an area of reduced thickness, separating the template from the imprinted medium, and, after separating the template from the imprinted medium, providing a layer of an etch resistant material on the pattern feature.

摘要翻译： 公开了一种压印方法，其在一个实施例中涉及使基板上的可压印介质与模板接触以在介质中形成压印，所述压印包括图案特征和厚度减小的区域，将模板与压印介质分离， 在从压印介质分离模板之后，在图案特征上提供耐蚀刻材料层。

公开(公告)号：US20090290135A1

公开(公告)日：2009-11-26

申请号：US12512754

申请日：2009-07-30

申请人： Joeri Lof ,  Hans Butler ,  Sjoerd Nicolaas Lambertus Donders ,  Aleksey Kolesnychenko ,  Erik Roelof Loopstra ,  Hendricus Johannes Maria Meijer ,  Jeroen Johannes Sophia Maria Mertens ,  Johannes Catharinus Hubertus Mulkens ,  Roelof Aeilko Siebrand Ritsema ,  Frank Van Schaik ,  Timotheus Franciscus Sengers ,  Klaus Simon ,  Joannes Theodoor De Smit ,  Alexander Straaijer ,  Helmar San Santen

发明人： Joeri Lof ,  Hans Butler ,  Sjoerd Nicolaas Lambertus Donders ,  Aleksey Kolesnychenko ,  Erik Roelof Loopstra ,  Hendricus Johannes Maria Meijer ,  Jeroen Johannes Sophia Maria Mertens ,  Johannes Catharinus Hubertus Mulkens ,  Roelof Aeilko Siebrand Ritsema ,  Frank Van Schaik ,  Timotheus Franciscus Sengers ,  Klaus Simon ,  Joannes Theodoor De Smit ,  Alexander Straaijer ,  Helmar San Santen

IPC分类号： G03B27/42

CPC分类号： G03F7/70341 ,  G03F7/707 ,  G03F7/7085 ,  G03F7/70866

摘要： A lithographic projection apparatus includes a support structure configured to hold a patterning device, the patterning device configured to pattern a beam of radiation according to a desired pattern; a projection system configured to project the patterned beam onto a target portion of a substrate; a substrate table configured to hold the substrate, the substrate table including a support surface configured to support an intermediary plate between the projection system and at least one of the substrate and an object positioned on the substrate table and not in contact with the at least one of the substrate and the object; and a liquid supply system configured to provide a liquid, through which the beam is to be projected, in a space between the projection system and the at least one of the substrate and the object.

摘要翻译： 光刻投影装置包括被配置为保持图案形成装置的支撑结构，所述图案形成装置被配置为根据期望的图案对辐射束进行图案化; 投影系统，被配置为将图案化的光束投影到基板的目标部分上; 被配置为保持所述基板的基板台，所述基板台包括支撑表面，所述支撑表面被构造成支撑所述投影系统与所述基板和位于所述基板台上的物体中的至少一个之间的中间板，并且不与所述至少一个 的基材和物体; 以及液体供应系统，其构造成在所述投影系统和所述基板和所述物体中的至少一个之间的空间中提供待投射所述光束的液体。