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公开(公告)号:US20050130145A1
公开(公告)日:2005-06-16
申请号:US10491355
申请日:2002-10-03
申请人: Henry Yue , Bridget Warren , Patricia Lehr-Mason , Uyen Tran , Brendan Duggan , Kavitha Thangavelu , Junming Yang , Yuming Xu , Y. Tang , Narinder Chawla , Vicki Elliott , Ian Forsythe , Shanya Becha , Monique Yao , Brooke Emerling , Jennifer Griffin , Preeti Lal , Yeganeh Zebarjadian , Mariah Baughn , Ernestine Lee , Soo Lee , Jayalaxmi Ramkumar , Ann Gorvad , Amy Kable , Dyung Lu , Mark Borowsky
发明人: Henry Yue , Bridget Warren , Patricia Lehr-Mason , Uyen Tran , Brendan Duggan , Kavitha Thangavelu , Junming Yang , Yuming Xu , Y. Tang , Narinder Chawla , Vicki Elliott , Ian Forsythe , Shanya Becha , Monique Yao , Brooke Emerling , Jennifer Griffin , Preeti Lal , Yeganeh Zebarjadian , Mariah Baughn , Ernestine Lee , Soo Lee , Jayalaxmi Ramkumar , Ann Gorvad , Amy Kable , Dyung Lu , Mark Borowsky
IPC分类号: A01K67/027 , A61K38/00 , A61K45/00 , A61P1/00 , A61P1/04 , A61P1/16 , A61P1/18 , A61P3/10 , A61P5/00 , A61P7/00 , A61P7/02 , A61P7/04 , A61P7/06 , A61P9/04 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/00 , A61P19/02 , A61P19/06 , A61P19/10 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/28 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/02 , A61P37/08 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/50 , G01N33/53 , G01N33/566 , G01N37/00 , A61K38/17 , C07H21/04 , C12N9/00
CPC分类号: C07K14/47 , A01K2217/05 , C12N9/6421
摘要: Various embodiments of the invention provide human secreted proteins (SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译: 本发明的各种实施方案提供鉴定和编码SECP的人分泌蛋白(SECP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其它实施方案提供用于诊断,治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号:US20050069876A1
公开(公告)日:2005-03-31
申请号:US10473519
申请日:2002-03-29
申请人: Mariah Baughn , Neil Burford , Li Ding , Brendan Duggan , Vicki Elliott , Ian Forsythe , Ameena Gandhi , Kimberly Gietzen , Jennifer Griffin , Ann He , Cynthia Honchell , Craig Ison , Preeti Lal , Ernestine Lee , Sally Lee , Dyung Alina Lu , Patricia Mason , Madhusudan Sanjanwala , Anita Swarnakar , Jayalaxmi Ramkumar , Y Tom Tang , Kavitha Thangavelu , Uyen Tran , Narinder Chawla , Bridget Warren , Monique Yao , Yuming Xu , Henry Yue
发明人: Mariah Baughn , Neil Burford , Li Ding , Brendan Duggan , Vicki Elliott , Ian Forsythe , Ameena Gandhi , Kimberly Gietzen , Jennifer Griffin , Ann He , Cynthia Honchell , Craig Ison , Preeti Lal , Ernestine Lee , Sally Lee , Dyung Alina Lu , Patricia Mason , Madhusudan Sanjanwala , Anita Swarnakar , Jayalaxmi Ramkumar , Y Tom Tang , Kavitha Thangavelu , Uyen Tran , Narinder Chawla , Bridget Warren , Monique Yao , Yuming Xu , Henry Yue
IPC分类号: G01N33/50 , A01K67/00 , A61K38/00 , A61K39/395 , A61K45/00 , A61P1/04 , A61P1/16 , A61P3/10 , A61P5/16 , A61P7/00 , A61P7/06 , A61P9/10 , A61P9/12 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/06 , A61P19/04 , A61P19/06 , A61P19/10 , A61P21/04 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P27/06 , A61P27/12 , A61P29/00 , A61P31/00 , A61P31/18 , A61P33/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/08 , C07H21/04 , C07K14/47 , C07K16/18 , C07K16/46 , C07K19/00 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , G01N37/00
CPC分类号: C07K14/47 , A01K2217/05 , A61K38/00
摘要: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译: 本发明提供鉴定和编码SECP的人分泌蛋白(SECP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号:US20050155089A1
公开(公告)日:2005-07-14
申请号:US10820474
申请日:2004-04-07
申请人: Preeti Lal , Y. Tang , Gina Gorgone , Neil Corley , Karl Guegler , Mariah Baughn , Ingrid Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer Hillman , Olga Bandman
发明人: Preeti Lal , Y. Tang , Gina Gorgone , Neil Corley , Karl Guegler , Mariah Baughn , Ingrid Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer Hillman , Olga Bandman
IPC分类号: G01N33/68 , A61K38/00 , A61K39/395 , A61K45/00 , A61P9/00 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , A01K67/00 , C07H21/04 , C12N9/64
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US20050107588A1
公开(公告)日:2005-05-19
申请号:US10495148
申请日:2002-11-13
申请人: Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
发明人: Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
IPC分类号: C07K14/47 , C07K14/705 , C07H21/04
CPC分类号: C07K14/705 , C07K14/47
摘要: Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, anti-bodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译: 本发明的各种实施方案提供了识别和编码REMAP的人受体和膜相关蛋白(REMAP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与REMAP异常表达相关的紊乱的方法。
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公开(公告)号:US20050053987A1
公开(公告)日:2005-03-10
申请号:US10893888
申请日:2004-07-20
申请人: Preeti Lal , Karl Guegler , Gina Gorgone , Neil Corley , Mariah Baughn , Y. Tang , Jennifer Hillman , Olga Bandman , Yalda Azimzai , Janice Au-Young , Henry Yue , Dyung Lu , Junming Yang
发明人: Preeti Lal , Karl Guegler , Gina Gorgone , Neil Corley , Mariah Baughn , Y. Tang , Jennifer Hillman , Olga Bandman , Yalda Azimzai , Janice Au-Young , Henry Yue , Dyung Lu , Junming Yang
CPC分类号: C12N9/0004 , A61K38/00
摘要: The invention provides human oxidoreductase molecules (OXRE) and polynucleotides which identify and encode OXRE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of OXRE.
摘要翻译: 本发明提供人氧化还原酶分子(OXRE)和识别和编码OXRE的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与OXRE表达相关的障碍的方法。
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公开(公告)号:US20050084936A1
公开(公告)日:2005-04-21
申请号:US10965898
申请日:2004-10-18
申请人: Preeti Lal , Olga Bandman , Jennifer Hillman , Janice Au-Young , Y. Tang , Henry Yue , Purvi Shah , Karl Guegler , Neil Corley
发明人: Preeti Lal , Olga Bandman , Jennifer Hillman , Janice Au-Young , Y. Tang , Henry Yue , Purvi Shah , Karl Guegler , Neil Corley
IPC分类号: C12N15/09 , A61K38/00 , A61K45/00 , A61P35/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P21/02 , C12Q1/68 , G01N37/00 , C07H21/04 , C07K14/705
CPC分类号: C07K14/4702 , A61K38/00
摘要: The invention provides human regulatory proteins collectively designated HRGP, and polynucleotides which identify and encode these molecules. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing, treating, and preventing disorders associated with expression of human regulatory proteins.
摘要翻译: 本发明提供了统称为HRGP的人调节蛋白,以及鉴定和编码这些分子的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了用于诊断,治疗和预防与人类调节蛋白表达相关的紊乱的方法。
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公开(公告)号:US20070054312A1
公开(公告)日:2007-03-08
申请号:US11594148
申请日:2006-11-08
申请人: Y. Tang , Preeti Lal , Jennifer Hillman , Henry Yue , Karl Guegler , Neil Corley , Olga Bandman , Chandra Patterson , Gina Gorgone , Matthew Kaser , Mariah Baughn , Janice Au-Young
发明人: Y. Tang , Preeti Lal , Jennifer Hillman , Henry Yue , Karl Guegler , Neil Corley , Olga Bandman , Chandra Patterson , Gina Gorgone , Matthew Kaser , Mariah Baughn , Janice Au-Young
IPC分类号: C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/705 , A61K38/17
CPC分类号: C07K16/28 , A61K38/00 , C07K14/705 , C07K2317/24 , C07K2317/622 , C07K2317/76 , G01N33/68
摘要: The invention provides human transmembrane proteins (HTMPN) and polynucleotides which identify and encode HTMPN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HTMPN.
摘要翻译: 本发明提供了人跨膜蛋白(HTMPN)和识别和编码HTMPN的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与HTMPN表达相关的障碍的方法。
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公开(公告)号:US20050214795A1
公开(公告)日:2005-09-29
申请号:US10974440
申请日:2004-10-26
申请人: Jennifer Hillman , Olga Bandman , Preeti Lal , Henry Yue , Roopa Reddy , Y. Tang , Edward Gerstin , Chandra Arvizu , Mariah Baughn , Yalda Azimzai , Dyung M. Lu
发明人: Jennifer Hillman , Olga Bandman , Preeti Lal , Henry Yue , Roopa Reddy , Y. Tang , Edward Gerstin , Chandra Arvizu , Mariah Baughn , Yalda Azimzai , Dyung M. Lu
IPC分类号: C12N15/09 , A61K38/00 , A61K45/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P21/02 , C12P21/08 , C12Q1/68 , C07H21/04 , C12N9/22
CPC分类号: C07K14/4702 , A61K38/00
摘要: The invention provides human transcriptional regulator molecules (HTRM) and polynucleotides which identify and encode HTRM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HTRM.
摘要翻译: 本发明提供了人转录调节分子(HTRM)和识别和编码HTRM的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HTRM表达相关的障碍的方法。
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公开(公告)号:US20050003447A1
公开(公告)日:2005-01-06
申请号:US10921707
申请日:2004-08-19
申请人: Preeti Lal , Y. Tang , Henry Yue , Jennifer Jackson , Olga Bandman , Neil Corley , Karl Guegler , Chandra Arvizu , Yalda Azimzai , Mariah Baughn
发明人: Preeti Lal , Y. Tang , Henry Yue , Jennifer Jackson , Olga Bandman , Neil Corley , Karl Guegler , Chandra Arvizu , Yalda Azimzai , Mariah Baughn
摘要: The invention provides human cytoskeleton associated proteins (CYSKP) and polynucleotides which identify and encode CYSKP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CYSKP.
摘要翻译: 本发明提供鉴定和编码CYSKP的人类细胞骨架相关蛋白(CYSKP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与CYSKP表达相关的疾病的方法。
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公开(公告)号:US20050042738A1
公开(公告)日:2005-02-24
申请号:US10478519
申请日:2002-05-22
申请人: Anita Swarnakar , Ann Gorvad , April Hafalia , Brendan Duggan , Brooke Emerling , Craig Ison , Danniel Nguyen , Ernestine Lee , Henry Yue , Huibin Yue , Ian Forsythe , Joana Li , Kavitha Thangavelu , Narinder Chawla , Neil Burford , Patricia Mason , Preeti Lal , Sally Lee , Shanya Becha , Y. Tang
发明人: Anita Swarnakar , Ann Gorvad , April Hafalia , Brendan Duggan , Brooke Emerling , Craig Ison , Danniel Nguyen , Ernestine Lee , Henry Yue , Huibin Yue , Ian Forsythe , Joana Li , Kavitha Thangavelu , Narinder Chawla , Neil Burford , Patricia Mason , Preeti Lal , Sally Lee , Shanya Becha , Y. Tang
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/04 , A61P1/12 , A61P1/16 , A61P1/18 , A61P3/04 , A61P3/06 , A61P3/08 , A61P3/10 , A61P3/12 , A61P5/14 , A61P5/38 , A61P5/40 , A61P7/00 , A61P7/04 , A61P7/06 , A61P7/08 , A61P9/06 , A61P9/10 , A61P9/12 , A61P11/00 , A61P13/00 , A61P13/02 , A61P13/08 , A61P13/12 , A61P15/00 , A61P15/08 , A61P15/10 , A61P17/00 , A61P17/02 , A61P17/06 , A61P19/02 , A61P19/04 , A61P19/06 , A61P19/10 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P27/02 , A61P27/12 , A61P27/16 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P33/02 , A61P33/10 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06 , A61P37/08 , C07K1/22 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C12N9/00
摘要: The invention provides human carbohydrate-associated proteins (CHOP) and polynucleotides which identify and encode CHOP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CHOP.
摘要翻译: 本发明提供了识别和编码CHOP的人类碳水化合物相关蛋白(CHOP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与CHOP异常表达相关的疾病的方法。
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