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公开(公告)号：US20250145711A1
公开(公告)日：2025-05-08
申请号：US18830184
申请日：2024-09-10
Applicant: Janssen Biotech, Inc.
Inventor： Adam Zwolak , Raymond Brittingham , Scott R. Brodeur , Rajkumar Ganesan , Sherry Lynn La Porte , Jinquan Luo , Fang Yi , Colleen M. Kane , Triveni K. Bhatt
Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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公开(公告)号：US12129310B2
公开(公告)日：2024-10-29
申请号：US18122948
申请日：2023-03-17
Applicant: Janssen Biotech, Inc.
Inventor： Sanjaya Singh , Rajkumar Ganesan , Jun Chen , Iqbal S. Grewal
CPC classification number: C07K16/42 , G01N33/6857 , C07K2317/14 , C07K2317/34
Abstract: Molecules, including antibodies and antigen-binding fragments thereof that specifically bind to a linker peptide, and methods of producing and using the described antibodies and antigen-binding fragments are presented herein. Also presented herein methods of generating antibodies that specifically bind to an immunorecessive epitope.
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公开(公告)号：US12076413B2
公开(公告)日：2024-09-03
申请号：US17512195
申请日：2021-10-27
Applicant: JANSSEN BIOTECH, INC.
Inventor： Rajkumar Ganesan , Iqbal S. Grewal , Sanjaya Singh , Michael Riis Hansen
CPC classification number: A61K47/6897 , C07K16/2809 , A61K39/00 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/56 , C07K2317/565 , C07K2317/73
Abstract: Provided herein, in certain aspects, are antibodies that bind to T cell receptor (TCR) Vγ9 (TRGV9), TCR Vδ2 (TRDV2), or the TCR gamma/delta constant region (TRGDC), as well as recombinant cells containing the vectors, and compositions comprising the antibodies. Methods of making and using the antibodies are also provided.
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公开(公告)号：US11981932B2
公开(公告)日：2024-05-14
申请号：US17349328
申请日：2021-06-16
Applicant: JANSSEN BIOTECH, INC.
Inventor： Iqbal S. Grewal , Rajkumar Ganesan , Sanjaya Singh
IPC: C12N5/074 , A61K35/545 , C12N15/86
CPC classification number: C12N5/0696 , A61K35/545 , C12N15/86 , C12N2501/2315 , C12N2501/999 , C12N2502/1114
Abstract: Provided here in are methods of producing induced pluripotent stem cells (iPSCs) and isolated population of produced induced pluripotent stem cells (iPSCs). Also provided herein are methods of treating a subject in need thereof using the produced iPSCs or pharmaceutical compositions comprising the produced iPSCs.
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公开(公告)号：US11965024B2
公开(公告)日：2024-04-23
申请号：US17472198
申请日：2021-09-10
Applicant: JANSSEN BIOTECH, INC.
Inventor： Rajkumar Ganesan , Iqbal S. Grewal , Sanjaya Singh , Michael Riis Hansen
IPC: C07K16/28 , A61K39/00 , A61P35/00 , C07K16/30 , C12N5/0783
CPC classification number: C07K16/2809 , A61P35/00 , C07K16/28 , C07K16/2866 , C07K16/2878 , C07K16/3069 , C12N5/0636 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/565 , C07K2317/92
Abstract: Anti-Vβ17 antibodies or antigen binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, methods of producing the antibodies, and methods of using the antibodies for treating or preventing diseases.
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Patent Agency Ranking
公开(公告)号：US11866499B2
公开(公告)日：2024-01-09
申请号：US16417889
申请日：2019-05-21
Applicant: Janssen Biotech, Inc.
Inventor： Philip Cooper , Robin Ernst , Rajkumar Ganesan , Colleen Kane , Michael Russell , Sanjaya Singh , Sathyadevi Venkataramani , Sheng-Jiun Wu
CPC classification number: C07K16/2809 , A61P35/00 , A61K45/06
Abstract: The disclosure provided herein relates to monospecific and multispecific anti-TMEFF2 antibodies, and methods of producing and using the described antibodies.
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公开(公告)号：US20230365684A1
公开(公告)日：2023-11-16
申请号：US18307127
申请日：2023-04-26
Applicant: Janssen Biotech, Inc.
Inventor： Patrick John Doonan , Rajkumar Ganesan , Mehabaw Getahun Derebe , Sathyadevi Venkataramani , Sanjaya Singh , Iqbal S. Grewal , Karla R. Wiehagen
CPC classification number: C07K16/2803 , A61K39/4631 , A61K39/464411 , A61K39/4611 , C07K16/2809 , A61K51/1096 , A61K51/1027 , A61P35/00 , C07K2317/622 , C07K2317/22 , C07K2317/92 , C07K2317/24 , C07K2317/31 , C07K2317/73 , C07K2317/77
Abstract: The invention provides antigen binding domains that bind myeloid cell surface antigen CD33 protein comprising the antigen binding domains that bind CD33, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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公开(公告)号：US20230151083A1
公开(公告)日：2023-05-18
申请号：US17917916
申请日：2021-04-07
Applicant: Janssen Biotech, Inc.
Inventor： Kristof Van Kolen , Marc Mercken , Rupesh Nanjunda , Sanjaya Singh , Sherry La Porte , Jinquan Luo , Pharavee Jaiprasart , Sathya Venkataramani , Rajkumar Ganesan
CPC classification number: C07K16/18 , G01N33/6896 , A61P25/28 , C12N15/63 , C07K2317/56
Abstract: Monoclonal anti-PHF-tau antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, methods of producing the antibodies and using the antibodies for treating or preventing conditions such as tauopathies.
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公开(公告)号：US20220306738A1
公开(公告)日：2022-09-29
申请号：US17702042
申请日：2022-03-23
Applicant: Janssen Biotech, Inc.
Inventor： Kyle J. Bednar , Naresh Kumar , Sanjaya Singh , Danlin Yang , Rajkumar Ganesan
Abstract: Provided herein are multispecific antibodies, that bind to CD79b and CD22, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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公开(公告)号：US20210284731A1
公开(公告)日：2021-09-16
申请号：US17202004
申请日：2021-03-15
Applicant: Janssen Biotech, Inc.
Inventor： Rajkumar Ganesan , Iqbal S. Grewal , Sanjaya Singh
Abstract: Anti-TRGV9 molecules, such as anti-TRGV9 antibodies or antigen binding fragments thereof, are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, methods of producing the antibodies, and methods of using the antibodies for treating or preventing diseases.
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