公开(公告)号：US20070205004A1

公开(公告)日：2007-09-06

申请号：US11464919

申请日：2006-08-16

申请人： Michael Perkovich ,  Andrew Olah ,  Gary Johnson ,  Stanley Nerderman

发明人： Michael Perkovich ,  Andrew Olah ,  Gary Johnson ,  Stanley Nerderman

IPC分类号： A62C35/00

CPC分类号： F16L47/30 ,  A62C35/68 ,  B26D3/169 ,  F16L3/1016 ,  F16L17/04 ,  F16L41/12

摘要： Fire sprinkler system comprising a network of CPVC pipe lengths in which at least some of the pipe lengths are interconnected with mechanical devices having resilient sealing members that are chemically compatible with the CPVC composition. Repairs and system modifications can be made without the use of solvent cement. In-line joints are formed with a coupling device including a pair of arcuate coupling segments having a first end, a second end, and an interior concave surface extending between the first end and the second end. A longitudinal channel extends along the concave surface. At least one mechanical fastener is operative to detachably connect the pair of coupling segments. A resilient annular seal is located within the longitudinal channel of each segment. A branching device connects a branch pipe to a main pipe through an orifice in the main pipe utilizing a saddle-like sealing member. The pipe assemblies are able to pass UL testing protocols for wet fire sprinkler systems.

摘要翻译： 消防喷淋系统，包括CPVC管道网络，其中至少一些管道长度与具有与CPVC组合物化学相容的弹性密封构件的机械装置互连。 维修和系统修改可以在不使用溶剂水泥的情况下进行。 在线接头形成有联接装置，该联接装置包括一对弓形联接段，其具有在第一端和第二端之间延伸的第一端，第二端和内部凹面。 纵向通道沿凹面延伸。 至少一个机械紧固件可操作以可拆卸地连接该对联接段。 弹性环形密封件位于每个段的纵向通道内。 分支装置利用鞍形密封构件将分支管通过主管中的孔连接到主管。 管道组件能够通过UL防火喷淋系统的UL测试协议。

公开(公告)号：US20060148023A1

公开(公告)日：2006-07-06

申请号：US10872824

申请日：2004-06-21

申请人： David Phelps ,  Gary Johnson ,  Brian Lee ,  Zbigniew Darzynkiewicz ,  Jerzy Grabarek

发明人： David Phelps ,  Gary Johnson ,  Brian Lee ,  Zbigniew Darzynkiewicz ,  Jerzy Grabarek

IPC分类号： C12Q1/37

CPC分类号： C12Q1/37 ,  G01N33/5091 ,  G01N33/573 ,  G01N2500/04 ,  G01N2510/00 ,  G01N2800/52

摘要： The invention provides assay methods and reagents useful for evaluating the level of enzyme activities within living cells. Enzyme activity levels within living cells, such as Serine proteases, can be key determinates in assessing; 1) the presence of tumor (cancer) cells, 2) the predictive efficacy of a chemotherapeutic treatment regimen using a particular therapeutic agent or process, 4) the probability of graft rejection or acceptance, and 5) the disease state status of a cell. The identification of the up or down regulation relationships of serine proteases within living cell systems, provides a rapid, yet finely tuned mechanism for predicting the current and future physiological state of these cell populations.

摘要翻译： 本发明提供了可用于评估活细胞内酶活性水平的测定方法和试剂。 活细胞内的酶活性水平，如丝氨酸蛋白酶，可能是评估中的关键决定因素; 1）肿瘤（癌症）细胞的存在，2）使用特定治疗剂或过程的化学治疗方案的预测效果，4）移植排斥或接受的概率，以及5）细胞的疾病状态。 识别活细胞系统中丝氨酸蛋白酶的上调或下调调节关系，为预测这些细胞群体的当前和未来生理状态提供了一种快速但精细调节的机制。

公开(公告)号：US20060051853A1

公开(公告)日：2006-03-09

申请号：US11210471

申请日：2005-08-23

申请人： Gary Johnson

发明人： Gary Johnson

IPC分类号： C12Q1/68 ,  A01K67/00 ,  C12N9/12 ,  C12P21/06 ,  C07K16/40

CPC分类号： C12N9/1205 ,  A01K2207/15 ,  A01K2217/00 ,  A01K2217/05 ,  C07K16/40 ,  C07K2319/00

摘要： Isolated nucleic acid molecules encoding human MEKK proteins, and isolated MEKK proteins, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a human MEKK transgene. The invention further provides human MEKK fusion proteins and anti-human MEKK antibodies. Methods of using the human MEKK proteins and nucleic acid molecules of the invention are also disclosed, including methods for detecting human MEKK activity in a biological sample, methods of modulating human MEKK activity in a cell, and methods for identifying agents that modulate the activity of human MEKK.

摘要翻译： 提供了编码人MEKK蛋白的分离的核酸分子和分离的MEKK蛋白。 本发明进一步提供反义核酸分子，含有本发明的核酸分子的重组表达载体，已经引入了表达载体的宿主细胞和携带人MEKK转基因的非人转基因动物。 本发明还提供人MEKK融合蛋白和抗人MEKK抗体。 还公开了使用本发明的人MEKK蛋白质和核酸分子的方法，包括用于检测生物样品中的人MEKK活性的方法，调节细胞中人MEKK活性的方法，以及用于鉴定调节细胞活性的试剂的方法 人类MEKK。

公开(公告)号：US20050275439A1

公开(公告)日：2005-12-15

申请号：US11210290

申请日：2005-08-24

申请人： Gary Johnson

发明人： Gary Johnson

IPC分类号： H03L7/081 ,  H03L7/06

CPC分类号： H03L7/0814 ,  H03L7/0818

摘要： A method and apparatus is provided for providing a fine delay by switching on a capacitor delay. A coarse delay and/or a fine delay are implemented upon a reference signal based upon a phase shift between the reference signal and a feedback signal. A fine delay is implemented upon the reference signal based upon a phase shift between the reference signal and a feedback signal. Providing the fine delay includes switching on a capacitive delay. A synchronized output signal is generated based upon the fine delay.

公开(公告)号：US20050134000A1

公开(公告)日：2005-06-23

申请号：US10982227

申请日：2004-11-03

申请人： Gary Johnson ,  Joe Lessard

发明人： Gary Johnson ,  Joe Lessard

IPC分类号： A63B63/00 ,  A63B63/06

CPC分类号： A63B63/00 ,  A63B63/06 ,  A63B67/06

摘要： A game including a frame, a rotatable scoring assembly, and at least one playing piece. The at least one playing piece is thrown toward the rotatable scoring assembly, and points are scored by the playing piece coming to rest on predetermined portions of the scoring bar assembly.

摘要翻译： 一种包括框架，可旋转刻痕组件和至少一个玩具的游戏。 将至少一个玩具投掷到可旋转打分组件上，并且通过播放片在打标杆组件的预定部分上放置点进行刻痕。

公开(公告)号：US20050065537A1

公开(公告)日：2005-03-24

申请号：US10479351

申请日：2002-05-30

申请人： Vincent Tangherlini ,  Russell Ahlberg ,  Arkadiusza Strokosz ,  Gary Johnson ,  Matthew Wixey ,  Linda Phinuwong

发明人： Vincent Tangherlini ,  Russell Ahlberg ,  Arkadiusza Strokosz ,  Gary Johnson ,  Matthew Wixey ,  Linda Phinuwong

IPC分类号： A61B17/12 ,  A61B17/06 ,  A61B17/064 ,  A61B17/08 ,  A61B17/122 ,  A61B17/128 ,  A61B17/82 ,  A61L31/00 ,  A61L31/02 ,  C23C8/10

CPC分类号： C23C8/10 ,  A61B17/06066 ,  A61B17/064 ,  A61B17/0644 ,  A61B17/083 ,  A61B17/122 ,  A61B17/128 ,  A61B17/1285 ,  A61B17/82 ,  A61L31/022

摘要： A surgical device includes a structural portion which is formed of a first element, such as titanium, which has an outer surface and an inner core. A second element, such as oxygen, is combined with the first element without creating a shear plane, to create a concentration of the second element in the first element which varies from the outer surface to the inner core. In an associated method, the second element is driven into the first element under other than ambient conditions to develop a concentration gradient of the second element between the outer surface and the inner core of the first element.

摘要翻译： 手术装置包括由诸如钛的第一元件形成的结构部分，其具有外表面和内核。 诸如氧的第二元件与第一元件组合而不产生剪切平面，以产生第一元件中从外表面到内芯变化的浓度。 在相关联的方法中，第二元件在环境条件之外被驱动到第一元件中，以在第一元件的外表面和内芯之间形成第二元件的浓度梯度。

公开(公告)号：US06690918B2

公开(公告)日：2004-02-10

申请号：US09755768

申请日：2001-01-05

申请人： Michael Evans ,  Robert Evans ,  Charles Carinalli ,  Gary Johnson

发明人： Michael Evans ,  Robert Evans ,  Charles Carinalli ,  Gary Johnson

IPC分类号： H04B700

CPC分类号： H04L67/306 ,  H04W8/18 ,  H04W8/20 ,  H04W28/18 ,  H04W84/12

摘要： A system for anonymously initiating communication between system-connected communications devices is provided wherein the initiation of communication results from comparison and priority matching of profile information shared between the devices. The system in one aspect comprises at least two communications devices connected to the system, the communications devices having at least a microprocessor, a data-input mechanism, a display screen, a wireless local-area-network protocol application enhanced with short-wave radio communication capability installed per instance to each of the devices, and a profile comparison and matching application installed per instance to each of the devices. When any two of the devices come into short-wave radio range of each other, the devices activated, a wireless local-area-network is established and the in-range devices swap profiles, which are compared to profiles held locally on each device such that a profile match registering on at least one device enables the device matching the profile to signal the sending device of the matched profile in order to request communication between the devices.

摘要翻译： 提供了一种用于在系统连接的通信设备之间进行匿名发起通信的系统，其中通信的发起来自于在设备之间共享的简档信息的比较和优先级匹配。 该系统在一个方面包括连接到系统的至少两个通信设备，通信设备至少具有微处理器，数据输入机制，显示屏幕，利用短波无线电增强的无线局域网协议应用 每个实例向每个设备安装通信能力，以及每个实例安装到每个设备的配置文件比较和匹配应用程序。 当任何两个设备进入彼此的短波无线电范围时，激活设备，建立无线局域网，并且在范围内的设备交换配置文件与每个设备本地保存的配置文件进行比较 在至少一个设备上登记的配置文件匹配使能够匹配配置文件的设备向匹配配置文件的发送设备发信号，以便请求设备之间的通信。

公开(公告)号：US5394665A

公开(公告)日：1995-03-07

申请号：US147518

申请日：1993-11-05

申请人： Gary Johnson

发明人： Gary Johnson

IPC分类号： E04B2/74 ,  E04B2/72 ,  E04B2/76 ,  E04C3/32 ,  E04C2/38 ,  E04C3/04

CPC分类号： E04C3/32 ,  E04B2/766 ,  E04B2/723

摘要： A stud wall framing construction comprises a lower track; an upper track aligned with and vertically spaced from the lower track; and a plurality of vertically aligned studs positioned between the lower and upper tracks. The lower and upper end portions of the studs are positioned within the lower and upper tracks, respectively. Each of the lower and upper tracks includes a channel with opposed track sidewalls and a track base wall. The track sidewalls have a plurality of inwardly projecting track protrusions formed from the sidewalls. Each of the track protrusions on one of the sidewalls is paired with another track protrusion disposed across the opposite sidewall. The lower and upper end portions of the studs has opposed stud sidewalls and plurality of inwardly projecting stud protrusions formed from the stud sidewalls. Each of the stud protrusions on one of the stud sidewalls is paired with another stud protrusion disposed across the opposite stud sidewall. The track and stud protrusions are adapted such that each of the pair track protrusions nest into a respective pair of stud protrusions, thereby locking the studs in the tracks.

摘要翻译： 螺柱壁框架结构包括下轨道; 与所述下轨道对准并垂直间隔开的上轨道; 以及位于下轨道和上轨道之间的多个垂直排列的螺柱。 螺柱的下端部和上端部分别位于下轨道和上轨道内。 下轨道和上轨道中的每一个包括具有相对的轨道侧壁和轨道基座壁的通道。 轨道侧壁具有从侧壁形成的多个向内突出的轨道突起。 一个侧壁上的每个轨道突起与另一个跨越相对的侧壁设置的轨道突起配对。 螺柱的下端部和上端部具有相对的螺柱侧壁和由螺柱侧壁形成的多个向内突出的突出突起。 一个螺柱侧壁上的每个螺柱突起与另一个跨越相对的螺柱侧壁设置的螺柱突起配对。 轨道和螺柱突起适于使得每对轨道突起嵌入相应的一对螺柱突起中，从而将螺柱锁定在轨道中。

公开(公告)号：US5179959A

公开(公告)日：1993-01-19

申请号：US780128

申请日：1991-10-29

申请人： Henry Fishman ,  Robert Olshaker ,  Gary Johnson

发明人： Henry Fishman ,  Robert Olshaker ,  Gary Johnson

IPC分类号： A61B17/20

CPC分类号： A61B17/205

摘要： An allergy testing system, for testing a patient for a plurality of allergies at substantially the same time, comprises a housing containing a plurality of packages or capsules containing an allergen and a needle, the needles being spaced apart from each other. The needles preferably carry the respective allergens on their tips. The housing is placed against the skin of a patient and an actuator is operated to engage the packages to move the needles to pierce or prick the skin of the patient, thereby applying the respective allergens to the pierced or pricked skin of the patient.

摘要翻译： 一种过敏测试系统，用于在基本上同时测试多个过敏症的患者，包括含有多个包含变应原和针的包装或胶囊的外壳，所述针彼此间隔开。 针优选地在其尖端携带相应的过敏原。 将壳体放置在患者的皮肤上，并且致动器被操作以接合包装以移动针刺穿或刺穿患者的皮肤，从而将相应的变应原施加到患者的刺穿或刺伤的皮肤。

公开(公告)号：US20160095238A1

公开(公告)日：2016-03-31

申请号：US14867451

申请日：2015-09-28

申请人： Jeremy Krinitt ,  Peter Jekel ,  Michael Laskowski ,  Jae Chang ,  Dan Piening ,  Dennis Meece ,  Holly Tsourides ,  James Young ,  Joe Fansler ,  Gary Johnson ,  Dave Friedeck ,  Eric Colburn

发明人： Jeremy Krinitt ,  Peter Jekel ,  Michael Laskowski ,  Jae Chang ,  Dan Piening ,  Dennis Meece ,  Holly Tsourides ,  James Young ,  Joe Fansler ,  Gary Johnson ,  Dave Friedeck ,  Eric Colburn

IPC分类号： H05K5/02

CPC分类号： H05K7/14 ,  A47B96/067 ,  H05K5/0204

摘要： A mountable enclosure can include a base and a door pivotally connected along a vertical axis. The base and door can include electronic component mounting areas, horizontal cable management areas, and vertical cable management areas. A mounting system can include at least one enclosure and at least one bracket, the bracket having a rigid body with first, second, and third parallel surfaces wherein the first and third surfaces are on one plane and the second surface is on a different plane. The bracket can be fastened to the wall and the enclosure can be fastened to the bracket and the wall. Multiple enclosures can be installed in vertical alignment through a method that can require only one installer and the leveling of only the first bracket wherein notches in subsequent brackets are mated with pegs extending from the base of previously installed enclosures.

摘要翻译： 可安装的外壳可以包括基座和沿垂直轴线枢转地连接的门。 基座和门可以包括电子元件安装区域，水平电缆管理区域和垂直电缆管理区域。 安装系统可以包括至少一个外壳和至少一个支架，支架具有带有第一，第二和第三平行表面的刚体，其中第一和第三表面在一个平面上，而第二表面位于不同的平面上。 支架可以固定在墙壁上，外壳可以固定在支架和墙壁上。 可以通过一种仅需要一个安装程序的方法将多个机箱安装在垂直对齐中，并且仅对第一个支架进行调平，其中后一个托架中的槽口与从先前安装的机柜底部延伸的销钉相配合。