公开(公告)号：US20170246603A1

公开(公告)日：2017-08-31

申请号：US15596952

申请日：2017-05-16

Applicant: Life Technologies Corporation

Inventor： Michael E. Goodwin ,  Nephi D. Jones ,  Jeremy K. Larsen

IPC: B01F15/00 ,  B01F7/00 ,  C12M1/00 ,  B01F5/04 ,  B01F7/22 ,  C12M1/12 ,  C12M1/04 ,  B01F3/04 ,  B01F13/02

CPC classification number: B01F15/0085 ,  B01F3/04269 ,  B01F3/04439 ,  B01F3/04829 ,  B01F5/04 ,  B01F7/00341 ,  B01F7/22 ,  B01F11/0082 ,  B01F13/0255 ,  B01F2003/04276 ,  B01F2003/04297 ,  B01F2003/04312 ,  B01F2003/04326 ,  B01F2003/04361 ,  B01F2003/04382 ,  B01F2003/04397 ,  B01F2215/0073 ,  C12M23/14 ,  C12M23/20 ,  C12M23/26 ,  C12M27/04 ,  C12M29/06 ,  C12M37/00

Abstract: A container system includes a collapsible bag having an interior surface at least partially bounding a chamber, the chamber being adapted to hold a fluid. A sparger is disposed within the chamber of the bag, the sparger bounding a compartment and having an inside edge that encircles an opening passing through the sparger. At least a portion of the sparger is gas permeable. A tubular member is coupled to the sparger and is in communication with the compartment. A shaft passes into the chamber of the bag and through the opening of the sparger. A mixing element is secured to the shaft and is disposed within the chamber of the bag.

公开(公告)号：US09540606B2

公开(公告)日：2017-01-10

申请号：US14109684

申请日：2013-12-17

Applicant: Life Technologies Corporation ,  Baxalta Incorporated ,  Baxalta GmbH

Inventor： Kurt T. Kunas ,  Robert V. Oakley ,  Fauad F. Hasan ,  Michael E. Goodwin ,  Jeremy K. Larsen ,  Nephi D. Jones

IPC: C12M1/06 ,  B01F7/00 ,  B01F7/16 ,  B01F7/22 ,  B01F15/00 ,  C12M1/00

CPC classification number: C12M23/14 ,  B01F7/001 ,  B01F7/1695 ,  B01F7/22 ,  B01F15/00006 ,  B01F15/00831 ,  B01F15/0085 ,  B01F2215/0073 ,  C12M23/00 ,  C12M23/06 ,  C12M23/26 ,  C12M23/28 ,  C12M27/02 ,  C12M29/06 ,  Y10T29/49826

Abstract: A method of mixing a fluid includes positioning a flexible bag into the chamber of a support housing, the support housing having a plurality of baffles positioned so that the bag folds around the baffles. A fluid is delivered into a compartment of the flexible bag. A mixing element, such as an impeller, is moved within the compartment of the flexible bag so as to mix the fluid therein.

Abstract translation: 混合流体的方法包括将柔性袋定位到支撑壳体的室中，所述支撑壳体具有多个挡板，所述挡板被定位成使得袋围绕挡板折叠。 将流体输送到柔性袋的隔室中。 诸如叶轮的混合元件在柔性袋的隔室内移动，以便在其中混合流体。

公开(公告)号：US09284524B2

公开(公告)日：2016-03-15

申请号：US14088140

申请日：2013-11-22

Applicant: Life Technologies Corporation

Inventor： Clinton C. Staheli ,  Nephi D. Jones ,  Michael E. Goodwin

IPC: C12M1/06 ,  C12M1/00 ,  B01F3/04 ,  B01F7/16 ,  B01F7/18 ,  B01F15/00 ,  C12M1/12 ,  B01D47/05 ,  C12N1/10 ,  C12N1/12 ,  C12N1/14 ,  C12N1/20 ,  C12N5/00 ,  C12N5/04 ,  B01D5/00 ,  B01F7/00 ,  B01F15/06

CPC classification number: C12M23/14 ,  B01D5/0072 ,  B01D47/05 ,  B01F3/04241 ,  B01F3/04531 ,  B01F7/00691 ,  B01F7/1695 ,  B01F7/18 ,  B01F7/22 ,  B01F15/00071 ,  B01F15/00831 ,  B01F15/0085 ,  B01F15/065 ,  B01F2003/04191 ,  B01F2003/04297 ,  B01F2003/04673 ,  B01F2003/04865 ,  B01F2003/04872 ,  B01F2003/04879 ,  B01F2003/04893 ,  B01F2003/04921 ,  B01F2015/061 ,  B01F2215/0073 ,  C12M23/26 ,  C12M23/34 ,  C12M27/02 ,  C12M29/00 ,  C12M29/06 ,  C12M29/24 ,  C12M37/00 ,  C12M41/14 ,  C12M41/18 ,  C12N1/10 ,  C12N1/12 ,  C12N1/14 ,  C12N1/20 ,  C12N5/00 ,  C12N5/04 ,  C12N5/10 ,  F28B1/02 ,  F28F3/12 ,  F28F21/06 ,  F28F2255/02

Abstract: A heat exchanger system includes a heat exchanger having a body plate with a first side face and an opposing second side face, the body plate bounding a fluid channel disposed between the opposing side faces and extending between an inlet port and an outlet port, and a first side plate having an inside face. A flexible first bag includes of one or more sheets of polymeric material, the first bag bounding a fluid pathway that extends between a fluid inlet and a fluid outlet, the first bag being removably retained between the body plate and the first side plate so that at least a portion of the first bag rests against the first side face of the body plate when the fluid pathway of the first bag is filled with a fluid.

Abstract translation: 热交换器系统包括具有主板的热交换器，该主体板具有第一侧面和相对的第二侧面，主体板限定设置在相对侧面之间并在入口和出口之间延伸的流体通道， 第一侧板具有内表面。 柔性第一袋包括一片或多片聚合物材料，第一袋包围在流体入口和流体出口之间延伸的流体通道，第一袋可移除地保持在主体板和第一侧板之间，使得在 当第一袋的流体通道充满流体时，第一袋的至少一部分靠在主体板的第一侧面上。

公开(公告)号：US20150265958A1

公开(公告)日：2015-09-24

申请号：US14587976

申请日：2014-12-31

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jason D. Brown ,  Clinton C. Staheli ,  Nephi D. Jones

IPC: B01D46/00

Abstract: A filter assembly includes a casing having of a polymeric film and bounding a compartment, the casing having an inlet opening communicating with the compartment and a first outlet opening communicating with the compartment. A first filter includes a porous filter body through which gas can pass and has a pore size smaller than 1 μm, the first filter being coupled with the casing so that the filter body is at least partially disposed within compartment of the casing and so that gas passing through the compartment of the casing from the inlet opening to the first outlet opening must pass through the filter body.

Abstract translation: 过滤器组件包括具有聚合物膜并且限定隔室的壳体，所述壳体具有与隔室连通的入口开口和与隔室连通的第一出口开口。 第一过滤器包括多孔过滤器主体，气体可以通过该多孔过滤器主体，孔径小于1μm，第一过滤器与壳体联接，使得过滤器主体至少部分地设置在壳体的隔室内， 穿过套管的隔室从入口开口到第一出口开口必须通过过滤器本体。

公开(公告)号：US12214324B2

公开(公告)日：2025-02-04

申请号：US18353754

申请日：2023-07-17

Applicant: Life Technologies Corporation

Inventor： Jeffery C. Hurd ,  Nephi D. Jones ,  Jacob D. Lee

IPC: B01F27/231 ,  B01F23/231 ,  B01F27/07 ,  B01F27/113 ,  B01F27/2111 ,  B01F27/2121 ,  B01F27/2122 ,  B01F27/213 ,  B01F33/00 ,  B01F35/513 ,  C12M1/00 ,  C12M1/06 ,  C12M1/34 ,  B01F101/22 ,  B01F101/44

Abstract: A liquid mixing system includes a support housing at least partially bounding a compartment. A mount is secured to the support housing. A drive motor assembly is configured to engage a drive shaft for moving the drive shaft within the compartment of the support housing. A four bar linkage system extends between the mount and the drive motor assembly, the four bar linkage system being movable between a first position wherein the drive motor assembly is disposed at a first elevation and a second position wherein the drive motor assembly is disposed at a second elevation that is different from the first elevation.

公开(公告)号：US20250032970A1

公开(公告)日：2025-01-30

申请号：US18796135

申请日：2024-08-06

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jason D. Brown ,  Clinton C. Staheli ,  Nephi D. Jones

IPC: B01D46/58 ,  B01D46/00 ,  B01F23/231 ,  B01F27/2121 ,  B01F27/88 ,  B01F27/90 ,  B01F35/10 ,  B01F35/513 ,  C12M1/00 ,  C12M1/06 ,  C12M1/12

Abstract: A method for filtering a gas comprises passing a gas through a compartment of a filter assembly, the filter assembly comprising: an inlet opening; a first outlet opening; a casing comprising polymeric film and bounding the compartment, the compartment communicating with the inlet opening and the first outlet opening; and a first filter at least partially disposed within the compartment. The method further comprising forming a first seal across a first section of the casing at a location between the inlet opening and the first filter to form a first sub-compartment within the casing and severing the casing at a first location.

公开(公告)号：US20250010252A1

公开(公告)日：2025-01-09

申请号：US18893665

申请日：2024-09-23

Applicant: Life Technologies Corporation

Inventor： Nephi D. Jones ,  Jason D. Brown

IPC: B01F27/191 ,  B01F27/07 ,  B01F27/072 ,  B01F27/113 ,  B01F27/91 ,  B01F35/513 ,  B01F101/44 ,  C12M1/06

Abstract: A mixing system for mixing a liquid includes a first impeller segment having a first mount and a first mixing blade secured to the first mount and a second impeller segment having a second mount and a first mixing blade secured to the second mount, the second impeller segment being separate and discrete from the first impeller segment. One or more drive members are secured to the first impeller segment and the second impeller segment for concurrently rotating the first impeller segment and the second impeller segment about a rotational axis. The first impeller segment and the second impeller segment are secured to the one or more drive members so that a plane extending normal to the axis of rotation intersects with the first mixing blade of the first impeller segment and the first mixing blade of the second impeller segment.

公开(公告)号：US12005412B2

公开(公告)日：2024-06-11

申请号：US17236238

申请日：2021-04-21

Applicant: Life Technologies Corporation

Inventor： Nephi D. Jones ,  Brandon M. Knudsen ,  Whitt F. Woods

IPC: C12M1/02 ,  B01F27/07 ,  B01F27/213 ,  B01F27/807 ,  B01F27/88 ,  B01F27/91 ,  B01F31/20 ,  B01F31/23 ,  B01F35/42 ,  B01F35/43 ,  B01F35/513 ,  B01F35/71 ,  B01F35/75 ,  C12M1/00 ,  C12M1/06 ,  C12M3/00 ,  C12M3/06

CPC classification number: B01F35/513 ,  B01F27/071 ,  B01F27/213 ,  B01F27/807 ,  B01F27/88 ,  B01F27/91 ,  B01F31/201 ,  B01F31/23 ,  B01F35/42 ,  B01F35/421 ,  B01F35/43 ,  B01F35/712 ,  B01F35/7548 ,  C12M23/14 ,  C12M23/48 ,  C12M23/52 ,  C12M27/00 ,  C12M27/02 ,  C12M27/16 ,  C12M29/06 ,  B01F35/715

Abstract: A method for mixing a fluid includes: dispensing a first volume of a fluid into a flexible container, the flexible container being at least partially disposed within the chamber of a support housing; repeatedly moving the support housing and the flexible container contained therein so as to mix the first volume of fluid within the flexible container; adding further fluid into the flexible container after moving the support housing to form a second volume of fluid; and manipulating a mixing element within the flexible container so as to mix the second volume of fluid.

公开(公告)号：US11554335B2

公开(公告)日：2023-01-17

申请号：US16854358

申请日：2020-04-21

Applicant: Life Technologies Corporation

Inventor： Jason D. Brown ,  Clinton C. Staheli ,  Nephi D. Jones

IPC: B01D46/00 ,  C12M1/00 ,  C12M1/12 ,  C12M1/06 ,  B01D46/58 ,  B01F23/231 ,  B01F27/88 ,  B01F27/90 ,  B01F27/2121 ,  B01F35/10 ,  B01F35/513

Abstract: A method for filtering a gas includes passing a gas into a compartment of a casing that includes a polymeric film, the casing having: a first sleeve having a first outlet opening, a first filter being at least partially disposed within the first sleeve so that gas passing through the first sleeve must pass through the first filter; and a second sleeve having an second outlet opening, a second filter being at least partially disposed within the second sleeve so that gas passing through the second sleeve must pass through the second filter, the second sleeve being closed so that the gas passing into the compartment of the casing passes through the first sleeve and the first filter and directly contacts at least a portion of the first sleeve comprised of the polymeric film but does not pass through the second sleeve. Opening the second sleeve when a predetermined condition is met so that the gas passes through the second sleeve and the second filter.

公开(公告)号：US20220033753A1

公开(公告)日：2022-02-03

申请号：US17450812

申请日：2021-10-13

Applicant: Life Technologies Corporation

Inventor： Christopher D. Brau ,  Nephi D. Jones ,  Benjamin R. Madsen ,  Michael E. Goodwin

IPC: C12M1/00 ,  B01F13/02 ,  B01F3/04 ,  C12M1/02 ,  C12M1/34 ,  B01F7/22 ,  B01F15/00 ,  C12M1/06

Abstract: A system for oxygenating a biological culture includes a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween; a tubular member projecting into the compartment of the container and terminating at a terminal end; a gas supply coupled with the tubular member and being configured to blow gas through the tubular member; and a mixing element disposed within compartment of the container at a location between the terminal end of the tubular member and the bottom wall of the container, the mixing element being configured to mix the liquid.