ADDITIVE MANUFACTURING SYSTEM AND METHOD FOR RAILROAD RAIL AND TRAIN WHEEL REPAIR

    公开(公告)号:US20240131637A1

    公开(公告)日:2024-04-25

    申请号:US18048767

    申请日:2022-10-20

    IPC分类号: B23P6/00

    CPC分类号: B23P6/00

    摘要: Systems and methods in which worn railroad rails and wheels are repaired. For rail repair, a mobile additive manufacturing unit (i.e., 3D printer) operates along the rail and dispenses molten metal on the previously prepared portion of the rail. Reinforcing composite materials in powder form or pieces of composite materials may be added to the molten metal to enhance mechanical properties. For wheel repair, a fixed additive manufacturing unit is used in the same or similar manner as the mobile additive manufacturing unit for the rails albeit the wheel is rotated relative to the additive manufacturing unit. The repaired surface of the rails and wheels have dimension accuracies and surface finishes that are substantially the same as the original rails and wheels with the same or better mechanical strength and hardness as the original after resurfacing with grinding or milling tools.

    LASER ANTIREFLECTION DEVICE AND LASER APPARATUS COMPRISING SAME
    33.
    发明申请
    LASER ANTIREFLECTION DEVICE AND LASER APPARATUS COMPRISING SAME 有权
    激光抗反射装置和包含其的激光装置

    公开(公告)号:US20130243016A1

    公开(公告)日:2013-09-19

    申请号:US13989409

    申请日:2011-11-26

    IPC分类号: H01S3/00

    摘要: A laser anti-reflection device includes a polarizing beam splitter, a λ/4 wave plate and an absorber disposed in an outgoing light path of a laser emitting linearly polarized light with a wavelength of λ. The linearly polarized light from the laser passes through the polarizing beam splitter and the λ/4 wave plate in turn to become a circularly polarized light beam. Part of the circularly polarized light beam is then reflected by a workpiece to be processed along the original light path and passes the λ/4 wave plate to become a linearly polarized light beam with a polarization direction vertical to that of the outgoing linearly polarized light beam. The vertical polarized beam passes the polarizing beam splitter, deviates from the light path of the outgoing linearly polarized light beam and reaches the absorber. The laser anti-reflection device prevents reflected light from damaging the laser from high power lasers.

    摘要翻译: 激光防反射装置包括偏振分束器,λ/ 4波片和设置在发射波长为λ的线偏振光的激光的出射光路中的吸收体。 来自激光器的线偏振光依次通过偏振分束器和λ/ 4波片,成为圆偏振光束。 圆偏振光束的一部分然后沿着原始光路被待处理的工件反射,并使λ/ 4波片成为具有垂直于出射直线偏振光束的偏振方向的线偏振光束 。 垂直偏振光束通过偏振分束器,偏离出射线偏振光束的光路并到达吸收体。 激光防反射装置防止反射光从大功率激光器损坏激光。

    Power supply system, power cable distributor, power supply subrack and integrated equipment
    35.
    发明授权
    Power supply system, power cable distributor, power supply subrack and integrated equipment 有权
    电源系统,电力电缆分配器,电源框和一体化设备

    公开(公告)号:US07907416B2

    公开(公告)日:2011-03-15

    申请号:US12323103

    申请日:2008-11-25

    IPC分类号: H05K5/00

    CPC分类号: H05K7/1457 Y10T307/391

    摘要: A power supply system is provided, which includes a power supply subrack (PSS) and a power cable distributor (PCD). The PSS includes one or more power modules and a third connector (51), and the PCD is adapted to introduce one or more electrical signals from power input cables. The third connector (51) in the PSS is connected to the PCD and adapted to feed the introduced electrical signals to the power modules. Furthermore, a power cable distributor, a power supply subrack adapted to work with the PCD and an integrated equipment are provided.

    摘要翻译: 提供一个供电系统,其中包括电源框(PSS)和电力电缆分配器(PCD)。 PSS包括一个或多个电源模块和第三连接器(51),并且PCD适于从电力输入电缆引入一个或多个电信号。 PSS中的第三连接器(51)连接到PCD并适于将引入的电信号馈送到功率模块。 此外,还提供了电力电缆分配器,适于与PCD一起工作的电源框架和集成设备。

    SYNTHESIS OF DESACETOXYTUBULYSIN H AND ANALOGS THEREOF
    36.
    发明申请
    SYNTHESIS OF DESACETOXYTUBULYSIN H AND ANALOGS THEREOF 审中-公开
    脱氧葡萄球蛋白H及其类似物的合成

    公开(公告)号:US20100047841A1

    公开(公告)日:2010-02-25

    申请号:US12037457

    申请日:2008-02-26

    摘要: Compounds of formula I, XVI and XXI possess potent cell growth inhibitory activity. These compounds are described have therapeutic utility, particularly in the treatment of cancer as well as conditions and disorders related to uncontrolled cell growth: wherein the variables R1, R2, R3, R4, R5, X, Y and Z are described herein.

    摘要翻译: 式I,XVI和XXI的化合物具有强的细胞生长抑制活性。 描述了这些化合物具有治疗效用,特别是治疗癌症以及与不受控制的细胞生长相关的病症和病症:其中本文描述了变量R1,R2,R3,R4,R5,X,Y和Z。

    PTTG knockout rodent as a model to study mechanisms for various physiological phenomena, including diabetes
    39.
    发明授权
    PTTG knockout rodent as a model to study mechanisms for various physiological phenomena, including diabetes 有权
    PTTG敲除啮齿动物作为模型,研究各种生理现象的机制,包括糖尿病

    公开(公告)号:US06909030B2

    公开(公告)日:2005-06-21

    申请号:US09978146

    申请日:2001-10-15

    摘要: Disclosed is a null mutant (or knockout) rodent comprising in its germ cells an artificially induced PTTG null mutation. In some embodiments, the null mutant rodent can be generated by way of homologous recombination in an embryonic stem cell or germ cell. The inventive null mutant rodent can be used to study mammalian physiology at the cellular, tissue, and/or organismal level with respect to various phenotypes, including hyperglycemia, hypoinsulinaemia, hypoleptinemia, diabetes, chromosomal aneuploidy, premature centromere division, chromosomal damage, aberrant mitotic cellular division, thrombocytopenia, thymic hyperplasia, splenic hypoplasia, testicular hypoplasia, and female subfertility. Also disclosed is an animal model for diabetes. Also disclosed is a somatic or germ cell obtained from the null mutant rodent. Also disclosed is a cell line derived from a cell obtained from the null mutant rodent.

    摘要翻译: 公开了一种无效突变(或敲除)啮齿动物,其在其生殖细胞中包含人工诱导的PTTG无效突变。 在一些实施方案中,无效突变啮齿动物可以通过在胚胎干细胞或生殖细胞中的同源重组产生。 关于各种表型,本发明的无效突变啮齿动物可用于研究细胞,组织和/或生物体水平的哺乳动物生理学,包括高血糖症,低胰岛素血症,hypoleptinemia,糖尿病,染色体非整倍性,早熟着丝粒分裂,染色体损伤,异常有丝分裂 细胞分裂,血小板减少症,胸腺增生,脾发育不全,睾丸发育不全和女性亚不孕。 还公开了一种用于糖尿病的动物模型。 还公开了从无效突变啮齿动物获得的体细胞或生殖细胞。 还公开了衍生自从无效突变啮齿动物获得的细胞的细胞系。