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31.发明授权公开(公告)号：US09840577B2
公开(公告)日：2017-12-12
申请号：US15269516
申请日：2016-09-19
Inventor： Pooja Singhal , Thomas S. Wilson , Elizabeth Cosgriff-Hernandez , Duncan J. Maitland
IPC: C08G18/10 , C08G18/32 , C08G71/04 , C08G18/66 , A61B17/00 , C08G63/00 , C08G63/685 , C08J9/00 , C08G18/08 , C08G18/16 , C08G18/73 , C08G101/00
CPC classification number: C08G18/6622 , A61B17/0057 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , C08G18/10 , C08G18/14 , C08G18/165 , C08G18/73 , C08G63/00 , C08G63/6852 , C08G71/04 , C08G2101/005 , C08G2101/0083 , C08G2230/00 , C08G2280/00 , C08J9/00 , C08J2375/06
Abstract: Compositions and/or structures of degradable shape memory polymers (SMPs) ranging in form from neat/unfoamed to ultra low density materials of down to 0.005 g/cc density. These materials show controllable degradation rate, actuation temperature and breadth of transitions along with high modulus and excellent shape memory behavior. A method of m ly low density foams (up to 0.005 g/cc) via use of combined chemical and physical aking extreme blowing agents, where the physical blowing agents may be a single compound or mixtures of two or more compounds, and other related methods, including of using multiple co-blowing agents of successively higher boiling points in order to achieve a large range of densities for a fixed net chemical composition. Methods of optimization of the physical properties of the foams such as porosity, cell size and distribution, cell openness etc. of these materials, to further expand their uses and improve their performance.
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公开(公告)号：US20170252045A1
公开(公告)日：2017-09-07
申请号：US15599133
申请日：2017-05-18
Applicant: Jonathan Hartman , LAWRENCE LIVERMORE NATIONAL SECURITY, LLC , The Texas A&M University System
Inventor： Jason M. Ortega , William J. Benett , Ward Small , Thomas S. Wilson , Duncan J. Maitland , Jonathan Hartman
IPC: A61B17/12
CPC classification number: A61B17/12113 , A61B17/12022 , A61B17/12031 , A61B17/12181 , A61B2017/0061 , A61B2017/00871 , A61B2017/12077
Abstract: A system for treating an aneurysm in a blood vessel or vein, wherein the aneurysm has a dome, an interior, and a neck. The system includes a shape memory polymer foam in the interior of the aneurysm between the dome and the neck. The shape memory polymer foam has pores that include a first multiplicity of pores having a first pore size and a second multiplicity of pores having a second pore size. The second pore size is larger than said first pore size. The first multiplicity of pores are located in the neck of the aneurysm. The second multiplicity of pores are located in the dome of the aneurysm.
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公开(公告)号：US20170043512A1
公开(公告)日：2017-02-16
申请号：US15232619
申请日：2016-08-09
Inventor： Jennifer N. Rodriguez , Duncan J. Maitland , Thomas S. Wilson
CPC classification number: B29C44/5663 , A61L31/06 , A61L31/146 , A61L2400/16 , B29K2075/00 , B29K2105/046 , B29K2995/0093 , B32B5/18 , B32B5/32 , B32B2266/0278 , B32B2266/08 , B32B2535/00 , C08G18/3228 , C08G18/3278 , C08G18/3284 , C08G18/73 , C08G2101/00 , C08J9/38 , C08J2205/052 , C08J2207/10 , C08J2375/04 , C08L75/04
Abstract: Polymeric based closed cell foams, such as shape memory polymer foams, contain bubbles. Making these bubbles continuous is called reticulation. Disclosed are embodiments of a device and method to controllably reticulate polymer-based closed cell foams by puncturing the membranes of these polymer-based closed cell foams.
Abstract translation: 基于聚合物的闭孔泡沫，例如形状记忆聚合物泡沫，含有气泡。 使这些气泡连续地称为网状。 公开了通过刺穿这些基于聚合物的闭孔泡沫的膜来可控地网状聚合物基闭孔泡沫的装置和方法的实施方案。
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公开(公告)号：US20250145758A1
公开(公告)日：2025-05-08
申请号：US19015925
申请日：2025-01-10
Inventor： Keith Hearon , Landon D. Nash , Thomas Wilson , Duncan J. Maitland , Mark A. Wierzbicki
Abstract: An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein.
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公开(公告)号：US20250144266A1
公开(公告)日：2025-05-08
申请号：US19014977
申请日：2025-01-09
Inventor： Duncan J. Maitland , Todd Lawrence Landsman , Tyler Joseph Touchet , Elizabeth L. Cosgriff-Hernandez , Thomas S. Wilson
Abstract: An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (Tg) of the SMP foam to below 25° C. Other embodiments are described herein.
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Patent Agency Ranking
公开(公告)号：US12251500B2
公开(公告)日：2025-03-18
申请号：US18533319
申请日：2023-12-08
Applicant: THE TEXAS A&M UNIVERSITY SYSTEM , SHAPE MEMORY MEDICAL, INC
Inventor： Duncan J. Maitland , Todd L. Landsman , John Horn , Landon Nash , Chung Yeh
IPC: A61F2/945 , A61B17/12 , A61F2/07 , A61F2/954 , A61L31/06 , A61L31/14 , A61L31/18 , A61B17/00 , A61B90/00 , A61F2/82 , A61F2/89
Abstract: An embodiment includes a process for treating an abdominal aortic aneurysm (AAA) endoleak with a shape memory polymer (SMP) foam device. First, a bifurcated stent graft is placed within the aneurysm while a micro guidewire is positioned within the aneurysm for future catheter access. Second, after placing the iliac graft extension, a catheter is introduced over wire to deliver embolic foams. Third, embolic foams expand and conform to the aneurysm wall. Fourth, embolic foams create a stable thrombus to prevent endoleak formation by isolating peripheral vessels from the aneurysm volume.
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公开(公告)号：US20240245823A1
公开(公告)日：2024-07-25
申请号：US18586901
申请日：2024-02-26
Inventor： Duncan J. Maitland , Todd Lawrence Landsman , Tyler Joseph Touchet , Elizabeth L. Cosgriff-Hernandez , Thomas S. Wilson
CPC classification number: A61L15/18 , A61L15/26 , A61L15/425 , A61L15/46 , A61L24/0015 , A61L24/0036 , A61L24/0094 , A61F13/01017 , A61L2300/106 , A61L2300/404 , A61L2400/16
Abstract: An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (Tg) of the SMP foam to below 25° C. Other embodiments are described herein.
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公开(公告)号：US20240042107A1
公开(公告)日：2024-02-08
申请号：US18486236
申请日：2023-10-13
Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
Inventor： Duncan J. Maitland , Adam M. Orendain
CPC classification number: A61L31/06 , A61L31/146 , A61F2/07 , A61B17/12181 , A61B17/12118 , A61B17/12113 , A61L31/148 , A61L31/18
Abstract: An embodiment includes an apparatus comprising: a shape memory polymer (SMP) foam having an outside surface; and a membrane that encapsulates at least 50% of the outside surface of the SMP foam; wherein (a) the SMP foam includes a thermoset SMP, and (b) the membrane includes a thermoplastic polymer. Other embodiments are addressed herein.
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公开(公告)号：US11771435B2
公开(公告)日：2023-10-03
申请号：US17155493
申请日：2021-01-22
Inventor： Thomas S. Wilson , Ward Small, IV , William J. Benett , Jason M. Ortega , Duncan J. Maitland , Jonathan Hartman
CPC classification number: A61B17/12113 , A61B17/1214 , A61B17/1215 , A61B17/12145 , A61B17/12181 , A61B17/12163 , A61B2017/00871 , A61B2017/12054 , A61M25/0668 , A61M2025/0042
Abstract: An embodiment of the invention includes an expandable implant to endovascularly embolize an anatomical void or malformation, such as an aneurysm. An embodiment is comprised of a chain or linked sequence of expandable polymer foam elements. Another embodiment includes an elongated length of expandable polymer foam coupled to a backbone. Another embodiment includes a system for endovascular delivery of an expandable implant (e.g., shape memory polymer) to embolize an aneurysm. The system may include a microcatheter, a lumen-reducing collar coupled to the distal tip of the microcatheter, a flexible pushing element detachably coupled to an expandable implant, and a flexible tubular sheath inside of which the compressed implant and pushing element are pre-loaded. Other embodiments are described herein.
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公开(公告)号：US11597792B2
公开(公告)日：2023-03-07
申请号：US16758419
申请日：2018-10-29
Inventor： Grace Fletcher , Landon D. Nash , Kendal Ezell , Duncan J. Maitland
IPC: C08G18/10 , C08G18/32 , C08G18/08 , C08G18/34 , C08G18/73 , C08G18/75 , C08K5/03 , C08G18/50 , C08G101/00
Abstract: An embodiment includes a polymer composition comprising a thermoplastic polymer that: (a) is bonded to iodine, (b) includes a vinyl group, and (c) includes urethane linkages. Other embodiments are described herein.
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