公开(公告)号：US20090130672A1

公开(公告)日：2009-05-21

申请号：US11937865

申请日：2007-11-09

Applicant: Andre R. Abad ,  Ronald D. Flannagan ,  Bin Hu ,  Cao Guo Yu

Inventor： Andre R. Abad ,  Ronald D. Flannagan ,  Bin Hu ,  Cao Guo Yu

IPC: C12Q1/68

CPC classification number: C12Q1/6809 ,  C12Q1/689 ,  C12Q2541/101

Abstract: Methods and compositions for identifying novel pesticidal gene homologues are provided. Specifically, the methods of the invention comprise systematically designing oligonucleotide primers that are specific for a pesticidal gene of interest and performing successive rounds of PCR amplification of nucleic acid material from a microorganism, particularly a Bacillus thuringiensis strain, to identify novel homologues of known pesticidal genes. Oligonucleotide primers that can be used to practice the present methods are further disclosed.

公开(公告)号：US20080186201A1

公开(公告)日：2008-08-07

申请号：US11752874

申请日：2007-05-23

Applicant: Yihua Wang ,  Fan Zhang ,  Hua Zhang ,  Bin Hu ,  Tianhua Rong ,  Juanwei Zhong

Inventor： Yihua Wang ,  Fan Zhang ,  Hua Zhang ,  Bin Hu ,  Tianhua Rong ,  Juanwei Zhong

IPC: G08C15/06

CPC classification number: G01D4/004 ,  G01R22/063 ,  Y02B90/242 ,  Y04S20/322

Abstract: An intelligent system for collecting readings from electric meters, comprising the following components: several electric meters, a data concentrator connected to the electric meters, and a system main station connected to the concentrator wirelessly, in which: the electric meter for recording the consumed quantity of electricity by user, metering the quantity of electricity, measuring demand and making a fault recording, and supporting a time-sharing measurement and communication with the data concentrator by electric power carrier; a concentrator for providing intelligent relay management, implementing the communication with the electric meters and the system main station, the management of communication route of electric meters and the storage function of data; the system main station for realizing a stable bi-directional communication with the concentrator and several electric meters, reading data in the concentrator, collecting information on electric energy, synchronizing the time of the concentrator and the electric meters associated therewith, renewing time step tariff rate and meter parameters of the electric meters. Bi-directional stable communication between the main station and the intelligent electric meters and collection of electrical energy information and the adjustment of parameters of electric meters can be realized by transmission medium in the present invention. The system of the present invention features complete functions, stable user-friendly operation interface, and has good expansion potential. Therefore this system is an important technical means for user-side management. The present invention greatly improves management efficiency and economic benefits in the electrical power department.

Abstract translation: 一种用于从电表收集读数的智能系统，包括以下部件：几个电表，连接到电表的数据集中器和无线连接到集中器的系统主站，其中：用于记录消耗量的电表 用户计量用电量，测量需求量，进行故障记录，支持电力承运人与数据集中器的时间分析测量与通信; 提供智能继电器管理的集中器，实现与电表和系统主站的通信，电表通信路径的管理和数据的存储功能; 用于实现与集中器和几个电表的稳定双向通信的系统主站，在集中器中读取数据，收集关于电能的信息，同步集中器的时间和与之相关的电表的时间，更新时间步长关税率 和电表的仪表参数。 通过本发明的传输介质可以实现主站与智能电表之间的双向稳定通信，电能信息的采集和电表的参数调整。 本发明的系统具有功能齐全，操作界面稳定，扩展潜力大的特点。 因此，该系统是用户端管理的重要技术手段。 本发明大大提高了电力部门的管理效率和经济效益。

公开(公告)号：US20080165932A1

公开(公告)日：2008-07-10

申请号：US11959699

申请日：2007-12-19

Applicant: Hui Meng ,  Quanwei Song ,  Nan Jiang ,  Shangmin Sun ,  Chengxin Cao ,  Jinning Liang ,  Bin Hu ,  Yaohong Liu

Inventor： Hui Meng ,  Quanwei Song ,  Nan Jiang ,  Shangmin Sun ,  Chengxin Cao ,  Jinning Liang ,  Bin Hu ,  Yaohong Liu

IPC: H05G1/02

CPC classification number: G01V5/0008

Abstract: The present invention provides a vehicle-carried radiation inspection system having a simple structure with advantages of convenient operation, little scanning blind area and reliable safety performance. The system comprises a loading vehicle, a lifting device mounted to the loading vehicle and a radiation scanning inspection means fixedly mounted to the lifting device so as to ascend/descend together with the lifting device. The lifting device is configured to enable the lifting device and the radiation scanning inspection means as a whole to be apart from the ground by a predetermined safety distance when the loading vehicle is moving, and to enable the minimum distance therebetween during inspection to be less than the predetermined safety distance. According to the invention, the radiation scanning inspection means may be switched between higher and lower positions as required with the ascending/descending of its combination with the lifting device.

Abstract translation: 本发明提供一种结构简单的车载辐射检查系统，其操作方便，扫盲范围小，安全性能可靠。 该系统包括装载车辆，安装到装载车辆的提升装置和固定地安装到提升装置上以与提升装置一起上升/下降的辐射扫描检查装置。 提升装置构造成使得提升装置和放射线检查装置作为整体能够在装载车辆移动时离开地面预定的安全距离，并且使得在检查期间其最小距离小于 预定的安全距离。 根据本发明，辐射扫描检查装置可以随着与提升装置的组合的上升/下降的需要而在较高和较低位置之间切换。

公开(公告)号：US07352843B2

公开(公告)日：2008-04-01

申请号：US10580870

申请日：2004-12-02

Applicant: Haifeng Hu ,  Yucheng Wu ,  Shangmin Sun ,  Zhiqiang Chen ,  Guang Yang ,  Zhengyu Bai ,  Rongxuan Liu ,  Hongliang Yang ,  Jianjun Su ,  Jiantao Wang ,  Yanjun Han ,  Bin Hu ,  Quanwei Song ,  Nan Jiang ,  Hua Peng ,  Jianmin Li ,  Wanquan Shen ,  Zhizhong Liang

Inventor： Haifeng Hu ,  Yucheng Wu ,  Shangmin Sun ,  Zhiqiang Chen ,  Guang Yang ,  Zhengyu Bai ,  Rongxuan Liu ,  Hongliang Yang ,  Jianjun Su ,  Jiantao Wang ,  Yanjun Han ,  Bin Hu ,  Quanwei Song ,  Nan Jiang ,  Hua Peng ,  Jianmin Li ,  Wanquan Shen ,  Zhizhong Liang

IPC: G01N23/04

CPC classification number: G01V5/0008 ,  G01N23/04

Abstract: A combined mobile container inspection system, comprising: a radiation source; a chassis; a rotatable deck provided at an end of the upper surface of said chassis and rotatable with respect to said chassis, provided with a parallelogram bracket formed by a hingedly-connected four-bar linkage mechanism, wherein the cross link of the parallelogram bracket extends to form a horizontal cross arm with detectors, the other end of said horizontal cross arm is connected with a vertical upright arm, which is vertical or parallel to said horizontal cross arm; and a sliding deck provided at the rear end of the rotatable deck and movable upwardly and downwardly, said sliding deck is provided, in turn, with the radiation source, the X-ray therefrom is always right in the face of the detectors provided in the horizontal cross arm and vertical upright arm, calibrator and collimator.

Abstract translation: 一种组合的移动式集装箱检查系统，包括：辐射源; 底盘; 可旋转的甲板，其设置在所述底盘的上表面的端部并相对于所述底盘旋转，设置有由铰接连接的四杆连杆机构形成的平行四边形支架，其中平行四边形支架的交叉连接件延伸形成 具有检测器的水平横臂，所述水平横臂的另一端与垂直或平行于所述水平横臂的垂直立臂连接; 以及设置在可旋转甲板的后端并可向上和向下移动的滑动板，所述滑动甲板依次设置有辐射源，其X射线始终位于设置在 水平交叉臂和垂直立臂，校准器和准直器。

公开(公告)号：US07022255B2

公开(公告)日：2006-04-04

申请号：US10683258

申请日：2003-10-10

Applicant: Junaid Ahmed Siddiqui ,  Bin Hu

Inventor： Junaid Ahmed Siddiqui ,  Bin Hu

IPC: C09K13/00 ,  C09K13/04

CPC classification number: H01L21/3212 ,  C09G1/02 ,  C09K3/1409 ,  C09K3/1463

Abstract: A composition and associated method for chemical mechanical planarization (or other polishing) are described. The composition comprises an organometallic-modified colloidal abrasive and a nitrogen-containing polymer compound (e.g., a polyalkyleneimine, such as polyamidopolyethyleneimine). The composition possesses both high stability towards gelling and/or solids formation and high selectivity for metal removal in metal CMP. The composition may further comprise an oxidizing agent in which case the composition is particularly useful in conjunction with the associated method for metal CMP applications (e.g., copper CMP).

Abstract translation: 描述了用于化学机械平面化（或其它抛光）的组合物和相关方法。 该组合物包含有机金属改性的胶体磨料和含氮高分子化合物（例如，聚亚烷基亚胺，如聚酰胺聚乙烯亚胺）。 该组合物具有对胶凝和/或固体形成的高稳定性以及金属CMP中金属去除的高选择性。 组合物还可以包含氧化剂，在这种情况下，组合物特别适用于金属CMP应用的相关方法（例如，铜CMP）。

公开(公告)号：US06933410B2

公开(公告)日：2005-08-23

申请号：US10367402

申请日：2003-02-14

Applicant: Mahavir Prashad ,  Bin Hu ,  Olivier Lohse

Inventor： Mahavir Prashad ,  Bin Hu ,  Olivier Lohse

IPC: C07C209/62 ,  C07B61/00 ,  C07C209/44 ,  C07C211/41 ,  C07C211/42 ,  C07C233/06 ,  C07C233/32 ,  C07C233/33 ,  C07C235/66

CPC classification number: C07C209/62 ,  C07C211/42 ,  C07C233/06 ,  C07C233/32 ,  C07C233/33 ,  C07C2602/08

Abstract: A process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine and acid addition salts thereof from 2-aminoindan. The process comprises protecting the amino group of 2-aminoindan, acetylating the ring in the protected compound, reducing the acetyl group to ethyl to form a monoethyl derivative, acetylating the monoethyl derivative, reducing the acetyl group to form a diethyl derivative, deprotecting the latter by hydrolysis and recovering the product in free or salt form. The process does not use deleterious Grignard reagents or nitrites such as isoamyl nitrite, and provides high regioselectivity and high yield of 5,6-diethyl-2,3-dihydro-1H-inden-2-amine. In addition, the process uses acetyl halide as both a reactant and a solvent.

Abstract translation: 从2-氨基茚满制备5,6-二乙基-2,3-二氢-1H-茚-2-胺及其酸加成盐的方法。 该方法包括保护2-氨基茚满的氨基，乙酰化保护的化合物中的环，将乙酰基还原为乙基以形成单乙基衍生物，乙酰化单乙基衍生物，还原乙酰基以形成二乙基衍生物，使后者脱保护 通过水解并以游离或盐形式回收产物。 该方法不使用有害的格氏试剂或亚硝酸盐，例如亚硝酸异戊酯，并且提供高的区域选择性和高收率的5,6-二乙基-2,3-二氢-1H-茚-2-胺。 此外，该方法使用乙酰卤作为反应物和溶剂。

公开(公告)号：US20190185486A1

公开(公告)日：2019-06-20

申请号：US16326043

申请日：2017-08-14

Applicant: Wensheng Yu ,  Joseph A. Kozlowski ,  Ling Tong ,  Craig A. Cobum ,  Bin Hu ,  Bin Zhong ,  Jinglai Hao ,  Dahai Wang

Inventor： Wensheng Yu ,  Joseph A. Kozlowski ,  Ling Tong ,  Craig A. Cobum ,  Bin Hu ,  Bin Zhong ,  Jinglai Hao ,  Dahai Wang

IPC: C07D498/04 ,  A61K31/5365 ,  A61K31/496 ,  A61K45/06 ,  A61P31/14

Abstract: The present invention relates to novel Chromane-Substituted Tetracyclic Compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, A′, R2 R3, R4 and R5 are as defined herein. The present invention also relates to compositions comprising a Chromane-Substituted Tetracyclic Compound, and methods of using the Chromane-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.

公开(公告)号：US20170217940A1

公开(公告)日：2017-08-03

申请号：US15104584

申请日：2014-12-15

Applicant: Joseph KOZLOWSKI ,  Craig COBURN ,  Wensheng YU ,  Bin HU ,  Bin ZHONG ,  Jinglai HAO ,  Dahai WANG ,  Tao JI ,  MERCL SHARP & DOHME CORP.

Inventor： Joseph Kozlowski ,  Craig Coburn ,  Wensheng Yu ,  Ling Tong ,  Bin Hu ,  Bin Zhong ,  Jinglai Hao ,  Dahai Wang ,  Tao Ji

IPC: C07D405/14 ,  A61K31/4178 ,  A61K31/7072 ,  A61K45/06 ,  A61K31/4985

CPC classification number: C07D405/14 ,  A61K31/4155 ,  A61K31/4178 ,  A61K31/4985 ,  A61K31/7072 ,  A61K45/06 ,  C07D493/04 ,  A61K2300/00

Abstract: The present invention relates to novel Fused Tetracyclic Heterocyclic Compounds of Formula I: (I), wherein A, A′, R2A, R2B, R7, R8, R9, and R10 are defined herein. The compounds and their pharmaceutically acceptable salts are useful for the prophylaxis or treatment of infection by HCV and the prophylaxis, treatment, or delay in the onset of disease caused by HCV. The present invention also relates to pharmaceutical compositions comprising at least one Fused Tetracyclic Heterocyclic Compound, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines, and methods of using the Fused Tetracyclic Heterocyclic Compounds for treating or preventing HCV infection in a patient.

公开(公告)号：US20170081287A1

公开(公告)日：2017-03-23

申请号：US15310488

申请日：2015-05-19

Applicant: Tesfaye BIFTU ,  Purakkattle BIJU ,  Timothy A. BLIZZARD ,  Zhengxia CHEN ,  Matthew J. CLEMENTS ,  Mingxiang CUI ,  Jessica L. FRIE ,  William K. HAGMANN ,  Bin HU ,  Hubert JOSIEN ,  Anilkumar G. NAIR ,  Christopher W. PLUMMER ,  Cheng ZHU ,  Merck Sharp & Dohme Corp.

Inventor： Tesfaye Biftu ,  Purakkattle Biju ,  Timothy A. Blizzard ,  Zhengxia Chen ,  Matthew J. Clements ,  Mingxiang Cui ,  Jessica L. Frie ,  William K. Hagmann ,  Bin Hu ,  Hubert Josien ,  Anilkumar G. Nair ,  Christopher W. Plummer ,  Cheng Zhu

IPC: C07D221/16 ,  A61K31/438 ,  C07D405/12 ,  C07D401/12 ,  A61K31/444 ,  C07C61/39 ,  A61K31/192 ,  A61K31/4725 ,  A61K31/4709 ,  A61K31/538 ,  C07D413/12 ,  A61K31/55 ,  C07D215/14 ,  A61K31/47 ,  C07D401/04 ,  A61K45/06

CPC classification number: C07D221/16 ,  A61K31/192 ,  A61K31/366 ,  A61K31/397 ,  A61K31/435 ,  A61K31/438 ,  A61K31/444 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/4985 ,  A61K31/538 ,  A61K31/55 ,  A61K45/06 ,  C07C61/39 ,  C07C2602/08 ,  C07C2603/12 ,  C07D215/14 ,  C07D401/04 ,  C07D401/12 ,  C07D405/12 ,  C07D413/12 ,  A61K2300/00

Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

公开(公告)号：US20160324821A1

公开(公告)日：2016-11-10

申请号：US15187872

申请日：2016-06-21

Applicant: Lili Feng ,  Sven Erik Godtfredsen ,  Paul Allen Sutton ,  Mahavir Prashad ,  Michael J. Girgis ,  Bin Hu ,  Yugang Liu ,  Thomas J. Blacklock ,  Piotr Henryk Karpinski

Inventor： Lili Feng ,  Sven Erik Godtfredsen ,  Paul Allen Sutton ,  Mahavir Prashad ,  Michael J. Girgis ,  Bin Hu ,  Yugang Liu ,  Thomas J. Blacklock ,  Piotr Henryk Karpinski

IPC: A61K31/216 ,  C07D257/04 ,  C07C233/47 ,  A61K31/41

CPC classification number: A61K31/216 ,  A61K31/41 ,  A61K31/4422 ,  A61K31/5415 ,  A61K45/06 ,  A61K2300/00 ,  C07C233/47 ,  C07D207/50 ,  C07D257/04

Abstract: A method for treatment of a cardiovascular or renal condition or disease with a specific combination, linked pro-drug or a compound of an angiotensin receptor antagonist and a NEPi.