摘要:
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated β-amyloid deposits or β-amyloid levels in a patient.
摘要:
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.
摘要:
A method and apparatus for communications according to various aspects of the present invention comprises a switching system configured to receive optical signals and direct the optical signals along a selected optical path. The switching system suitably includes more than one switch, and at least one of the switches may include a variable refractive material having a first state and a second state, wherein the optical signal is transmitted via a first path when the variable refractive material is in the first state and the individual channel signal is transmitted via a second path when the variable refractive material is in the second state. The switching system may alternatively or additionally include a switch element having a reflective state and a transmissive state, wherein the optical signal is reflected via a first path when the switch element is in the reflective state and the individual channel signal is transmitted via a second path when the switch element is in the transmissive state.
摘要:
The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted alpha-2-macroglobulin-like polypeptides. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal brain mRNA (Clontech) (SEQ ID NO: 1) and uterus mRNA (Clontech) (SEQ ID NO: 26). Other aspects of the invention include vectors containing processes for producing novel human secreted alpha-2-macroglobulin-like polypeptides, and antibodies specific for such polypeptides.
摘要翻译:本发明提供由这样的多核苷酸编码的新的多核苷酸和多肽,其对应于新型人分泌的α-2-巨球蛋白样多肽的突变体或其变体。 这些多核苷酸包含从胎儿脑mRNA(Clontech)(SEQ ID NO:1)和子宫mRNA(Clontech)(SEQ ID NO:26)的cDNA文库中分离的核酸序列。 本发明的其它方面包括含有产生新的人分泌的α-2-巨球蛋白样多肽的方法的载体和对这些多肽特异的抗体。
摘要:
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.
摘要:
An electronic package and/or package lid includes at least one connection slot for receiving a line, such as an optical fiber. The package and/or package lid also includes at least one sealant slot proximate the connection slot. Optical fibers are connected to a component, such as an opto-electronic component, through the connection slot. A sealant provided via the sealant slot hermetically seals the optical fibers within the connection slot.
摘要:
This invention provides aryloxy indole derivatives which are useful for the treatment of diseases affected by disorders of the serotonin-affected neurological systems, such as depression and anxiety, the compounds having the formula: wherein R1 is H or alkyl; R2, R3, and R4 are H, alkyl, or halogen; X is H, halogen, CN, or C1-C6 alkoxy; Z is (CH2)n or carbonyl; n is 1 or 2; and the dashed line indicates an optional double bond; or a pharmaceutically acceptable salt thereof.