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39 条记录 (耗时 0.033 秒)

    Intercalates, exfoliates and concentrates thereof formed with protonated, non-carboxylic swelling agent and nylon intercalants polymerized in-situ via ring-opening polymerization
    31.
    发明申请
    Intercalates, exfoliates and concentrates thereof formed with protonated, non-carboxylic swelling agent and nylon intercalants polymerized in-situ via ring-opening polymerization 失效
    由质子化的非羧酸溶胀剂和通过开环聚合原位聚合的尼龙嵌入剂形成的插层，去角质和浓缩物

    公开(公告)号：US20050256244A1

    公开(公告)日：2005-11-17

    申请号：US11152405

    申请日：2005-06-14

    申请人： Ying Liang ,  Tie Lan ,  Scott Omachinski

    发明人： Ying Liang ,  Tie Lan ,  Scott Omachinski

    IPC分类号： C08K9/08 ,  C08K3/34

    CPC分类号： C08J5/005 ,  B82Y30/00 ,  C08J3/226 ,  C08J2367/02 ,  C08J2369/00 ,  C08J2377/02 ,  C08J2477/00 ,  C08K9/04 ,  C08K2201/011 ,  C08L77/00

    摘要： A method of manufacturing a nanocomposite composition comprising forming an intercalating composition comprising 1% to about 90% by weight of a purified sodium smectite clay that contains at least 75% Na+ ions based on the total interlayer exchangeable cations, that has been intercalated and thereby swollen sufficiently for polyamide monomer or oligomer intercalation, with a protonated organic, non-carboxylic acid moiety-containing onium ion swelling agent; and about 10% to about 99% of a lactam ring-containing monomer or oligomer, and heating the intercalating composition to a temperature above the melting point of the lactam to open the lactam ring and polymerize the lactam to form the polyamide while in contact with the smectite clay.

    摘要翻译： 一种制备纳米复合材料组合物的方法，包括形成包含1重量％至约90重量％的纯化钠蒙脱石粘土的嵌入组合物，其含有至少75％的Na + 已被插入，从而充分膨胀聚酰胺单体或低聚物嵌入，与质子化有机，非羧酸部分的鎓离子溶胀剂; 和约10％至约99％的含内酰胺环的单体或低聚物，并将嵌入组合物加热至高于内酰胺熔点的温度以打开内酰胺环并聚合内酰胺以形成聚酰胺，同时与 蒙皂石粘土。

    EX VIVO AND IN VIVO METHODS AND RELATED COMPOSITIONS FOR REGENERATING HEMATOPOIETIC STEM CELL POPULATIONS
    32.
    发明申请
    EX VIVO AND IN VIVO METHODS AND RELATED COMPOSITIONS FOR REGENERATING HEMATOPOIETIC STEM CELL POPULATIONS 审中-公开
    用于再生HEMATOPOIETIC干细胞群体的VIVO和VIVO方法和相关组合物

    公开(公告)号：US20120214728A1

    公开(公告)日：2012-08-23

    申请号：US13342628

    申请日：2012-01-03

    申请人： Gary Van Zant ,  Ying Liang

    发明人： Gary Van Zant ,  Ying Liang

    IPC分类号： A61K38/00 ,  C12N5/00

    CPC分类号： C12N5/0647 ,  C12N2500/14 ,  C12N2501/01 ,  C12N2501/998

    摘要： Various embodiments provide methods and related compositions for increasing the population size of hematopoietic stem cells (HSCs) in patients that may benefit from reconstitution of stem cells and/or differentiated cells of the blood lineage. The present methods enable the production of HSCs ex vivo and in vivo by reducing latexin expression and/or latexin activity within HSC exposed to various antagonists. Inhibition of latexin expression and/or latexin activity by various antagonists can promote HSC proliferation and/or inhibit HSC apoptosis. Antagonists that can reduce latexin expression and/or latexin activity can be utilized to regenerate endogenous HSCs within patients affected with disorders, diseases, cancers, or therapies for such conditions, that result in the depletion or reduction in HSCs.

    摘要翻译： 各种实施方案提供用于增加可能受益于重建血细胞系干细胞和/或分化细胞的患者中造血干细胞（HSC）的群体大小的方法和相关组合物。 本发明的方法能够通过降低暴露于各种拮抗剂的HSC内的乳胶蛋白表达和/或胶乳活性而离体和体内生产HSC。 通过各种拮抗剂抑制胶原蛋白表达和/或胶乳活性可促进HSC增殖和/或抑制HSC凋亡。 可以利用可以降低乳胶蛋白表达和/或乳胶蛋白活性的拮抗剂来再生患有疾病，疾病，癌症或这些病症的治疗的患者内源性HSC，导致HSC的消耗或减少。

    Peelable Sealant Containing Thermoplastic Composite Blends for Packaging Applications
    33.
    发明申请
    Peelable Sealant Containing Thermoplastic Composite Blends for Packaging Applications 有权
    包装用热塑性复合材料共混物的可剥离密封胶

    公开(公告)号：US20120207997A1

    公开(公告)日：2012-08-16

    申请号：US13449762

    申请日：2012-04-18

    申请人： Ying Liang ,  Panagiotis Kinigakis ,  Francis J. Rossi

    发明人： Ying Liang ,  Panagiotis Kinigakis ,  Francis J. Rossi

    IPC分类号： B32B15/08 ,  C08K3/34 ,  C08K3/26 ,  B29C47/06 ,  C08K3/30 ,  C08K3/10 ,  C08K3/38 ,  C09J5/10 ,  C08K5/5415 ,  C08K3/22

    CPC分类号： B32B27/08 ,  B32B7/06 ,  B32B15/08 ,  B32B27/10 ,  B32B27/18 ,  B32B27/32 ,  B32B27/36 ,  B32B2264/10 ,  B32B2264/104 ,  B32B2307/302 ,  B32B2307/31 ,  B32B2307/518 ,  B32B2439/00 ,  B32B2439/70

    摘要： A packaging system has a peelable seal section which includes a first sealing layer and a second sealing layer such that the first sealing layer contacts the second sealing layer to form a peelable seal. The first sealing layer includes thermoplastic polymer or a blend of thermoplastic polymers, an organoclay dispersed within the thermoplastic polymer, a first additional inorganic additive component dispersed within the thermoplastic polymer and a second additional inorganic additive component dispersed within the thermoplastic polymer. The first additional additive component and/or the second additional additive component is selected from the group consisting of calcium carbonate, hydrated magnesium silicate (talc), magnesium carbonate, titanium oxide, magnesium oxide, magnesium sulfate, barium sulfate, barium aluminates, barium borate, barium silicate and combinations thereof.

    摘要翻译： 包装系统具有可剥离密封部分，其包括第一密封层和第二密封层，使得第一密封层接触第二密封层以形成可剥离的密封。 第一密封层包括热塑性聚合物或热塑性聚合物的共混物，分散在热塑性聚合物内的有机粘土，分散在热塑性聚合物内的第一另外的无机添加剂组分和分散在热塑性聚合物内的第二另外的无机添加剂组分。 第一附加添加剂组分和/或第二另外的添加剂组分选自碳酸钙，水合硅酸镁（滑石），碳酸镁，氧化钛，氧化镁，硫酸镁，硫酸钡，铝酸钡，硼酸钡 ，硅酸钡及其组合。

    Ex vivo and in vivo methods and related compositions for generating hematopoietic stem cell populations
    37.
    发明申请
    Ex vivo and in vivo methods and related compositions for generating hematopoietic stem cell populations 失效
    用于产生造血干细胞群的离体和体内方法和相关组合物

    公开(公告)号：US20070116681A1

    公开(公告)日：2007-05-24

    申请号：US11540641

    申请日：2006-10-02

    申请人： Gary Van Zant ,  Ying Liang

    发明人： Gary Van Zant ,  Ying Liang

    IPC分类号： A61K35/14 ,  C12N5/08

    CPC分类号： C12N5/0647 ,  C12N2500/14 ,  C12N2501/01 ,  C12N2501/998

    摘要： Various embodiments provide methods and related compositions for increasing the population size of hematopoietic stem cells (HSCs) in patients that may benefit from reconstitution of stem cells and/or differentiated cells of the blood lineage. The present methods enable the production of HSCs ex vivo and in vivo by reducing latexin expression and/or latexin activity within HSC exposed to various antagonists. Inhibition of latexin expression and/or latexin activity by various antagonists can promote HSC proliferation and/or inhibit HSC apoptosis. Antagonists that can reduce latexin expression and/or latexin activity can be utilized to regenerate endogenous HSCs within patients affected with disorders, diseases, cancers, or therapies for such conditions, that result in the depletion or reduction in HSCs.

    摘要翻译： 各种实施方案提供用于增加可能受益于重建血细胞系干细胞和/或分化细胞的患者中造血干细胞（HSC）的群体大小的方法和相关组合物。 本发明的方法能够通过降低暴露于各种拮抗剂的HSC内的乳胶蛋白表达和/或胶乳活性而离体和体内生产HSC。 通过各种拮抗剂抑制胶原蛋白表达和/或胶乳活性可促进HSC增殖和/或抑制HSC凋亡。 可以利用可以降低乳胶蛋白表达和/或乳胶蛋白活性的拮抗剂来再生患有疾病，疾病，癌症或这些病症的治疗的患者内源性HSC，导致HSC的消耗或减少。

    Intercalates and exfoliates formed with long chain (C6+) or aromatic matrix polymer-compatible monomeric, oligomeric or polymeric intercalant compounds, and composite materials containing same
    39.
    发明授权
    Intercalates and exfoliates formed with long chain (C6+) or aromatic matrix polymer-compatible monomeric, oligomeric or polymeric intercalant compounds, and composite materials containing same 失效
    与长链（C6 +）或芳族基质聚合物相容的单体，低聚或聚合物插入剂化合物形成的嵌入层和去角质层，以及含有相同的复合材料

    公开(公告)号：US06242500B1

    公开(公告)日：2001-06-05

    申请号：US09580999

    申请日：2000-05-26

    申请人： Tie Lan ,  Ying Liang ,  Semeon Tsipursky ,  Gary W. Beal

    发明人： Tie Lan ,  Ying Liang ,  Semeon Tsipursky ,  Gary W. Beal

    IPC分类号： B01D2101

    CPC分类号： C09C3/10 ,  C01B33/44 ,  C01P2002/08 ,  C01P2002/72 ,  C01P2002/77 ,  C01P2004/54 ,  C08K9/04 ,  C08K9/08 ,  C09C1/42

    摘要： Intercalates formed by contacting a layered material, e.g., a phyllosilicate, with an intercalant surface modifier selected from the group consisting of a compound having an alkyl radical containing at least 6 carbon atoms, a compound containing an aromatic ring, and mixtures thereof, said surface modifier including a matrix material-reactive functional group, to sorb or intercalate the intercalant surface modifier between adjacent platelets of the layered material. Sufficient intercalant surface modifier is sorbed between adjacent platelets to expand the adjacent platelets to at least about 10 Å, up to about 100 Å. The intercalated complex can be combined with an organic liquid into a viscous carrier material, for delivery of the carrier material, or for delivery of an active compound; or the intercalated complex can be combined with a matrix polymer to form a strong, filled polymer matrix.

    摘要翻译： 通过使层状材料例如页硅酸盐与选自由含有至少6个碳原子的烷基的化合物的嵌入剂表面改性剂，含有芳香环的化合物及其混合物而形成的插层体，所述表面 改性剂包括基质材料反应性官能团，以吸附或嵌​​入分层材料的相邻片晶之间的嵌入剂表面改性剂。 在相邻血小板之间吸附足够的嵌入剂表面改性剂以将相邻的血小板膨胀至至少约10埃，至多约100埃。 插入的复合物可以与有机液体结合成粘性载体材料，用于递送载体材料或递送活性化合物; 或者插层的复合物可以与基质聚合物组合以形成强的，填充的聚合物基质。