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203 条记录 (耗时 0.025 秒)

    Method and apparatus for in situ formation of hydrogels
    31.
    发明授权
    Method and apparatus for in situ formation of hydrogels 有权
    用于原位形成水凝胶的方法和装置

    公开(公告)号：US6165201A

    公开(公告)日：2000-12-26

    申请号：US389784

    申请日：1999-09-03

    申请人： Amarpreet S. Sawhney ,  Patrick K. Campbell ,  David A. Melanson

    发明人： Amarpreet S. Sawhney ,  Patrick K. Campbell ,  David A. Melanson

    IPC分类号： A61B17/10 ,  A61B17/00 ,  A61M35/00 ,  B05B7/02 ,  A61B17/08 ,  A61M5/32

    CPC分类号： A61M35/00 ,  A61B17/00491 ,  A61B2017/00495 ,  A61M25/0071

    摘要： Methods and apparatus of forming in situ tissue adherent barriers are provided using a sprayer capable of applying two or more viscous crosslinkable solutions to tissue. The sprayer comprises separate spray nozzles for each of two or more crosslinkable solutions, wherein each nozzle is either surrounded by an annular gas flow outlet or in communication with a gas-pressurized chamber, and also may include valves that prevent backflow through the supply lines carrying the crosslinkable solutions, and a venting system for venting excess pressure for laparoscopic applications In the presence of gas flow, the crosslinkable solutions are atomized and mixed to form a spray. Multi-component hydrogel systems suitable for use with the inventive methods and apparatus are also described.

    摘要翻译： 使用能够向组织施加两种或更多种粘性可交联溶液的喷雾器提供形成原位组织粘附屏障的方法和装置。 喷雾器包括用于两个或多个可交联溶液中的每一个的单独的喷嘴，其中每个喷嘴被环形气流出口包围或与气体加压室连通，并且还可以包括防止回流通过供给管线 可交联溶液和用于排空腹腔镜应用的过压的排气系统在气流的存在下，将可交联溶液雾化并混合以形成喷雾。 还描述了适用于本发明方法和装置的多组分水凝胶体系。

    Methods for forming a nerve barrier
    32.
    发明授权
    Methods for forming a nerve barrier 有权

    公开(公告)号：US12096941B2

    公开(公告)日：2024-09-24

    申请号：US17388327

    申请日：2021-07-29

    申请人： Tulavi Therapeutics, Inc. ,  INCEPT, LLC

    发明人： Corinne Bright ,  Yong Ren ,  Ken Martin ,  Farhad Khosravi ,  Amarpreet S. Sawhney

    IPC分类号： A61B17/12 ,  A61F2/00 ,  A61F2/02 ,  A61F2/08 ,  A61L27/52

    CPC分类号： A61B17/12181 ,  A61F2/0059 ,  A61F2/02 ,  A61F2/08 ,  A61L27/52

    摘要： Disclosed are methods, devices and materials for the in situ formation of an implant for treating a nerve. A treatment site on a nerve is positioned within a cavity defined by a form. A transformable media is introduced into the form cavity to surround the treatment site. The media is permitted to undergo a transformation from a first, relatively flowable state to a second, relatively non flowable state to form a protective barrier surrounding the treatment site. The implant may be a growth inhibiting nerve cap to inhibit neuroma formation following planned or traumatic nerve injury, a growth permissive conduit for facilitating reconnection of a severed nerve, or an anchor for stabilizing a pain management electrode with respect to a nerve. Access to the nerve treatment site may be open surgical or percutaneous.

    ANCHORING STRAIN RELIEF MEMBER
    36.
    发明公开
    ANCHORING STRAIN RELIEF MEMBER 审中-公开

    公开(公告)号：US20240198047A1

    公开(公告)日：2024-06-20

    申请号：US18587596

    申请日：2024-02-26

    申请人： Incept, LLC

    发明人： Ryan McNally Bean ,  Raymond Lareau

    IPC分类号： A61M25/00 ,  A61M25/09

    CPC分类号： A61M25/0075 ,  A61M25/0097 ,  A61M25/09 ,  A61M2025/0079 ,  A61M2025/091 ,  A61M2205/0216

    摘要： An anchor strain relief member provides resistance to disengagement from a hemostatic valve due to forces tending to force the catheter in a proximal direction. The anchoring strain relief member is distal to a hub, joined to the catheter outer surface, and comprises a sealing portion that has at least one ridge that has a ridge tip and a ridge height defined by a distance from the ridge tip to the catheter central axis. Methods of forming a nested catheter system are described using a catheter with an anchor strain relief as the inner catheter for the nested catheter set. Systems of a hemostatic valve and a suitable catheter with an anchor strain relief member can provide for desired assemblies of components.

    ENHANCED FLEXIBILITY NEUROVASCULAR CATHETER
    37.
    发明公开
    ENHANCED FLEXIBILITY NEUROVASCULAR CATHETER 审中-公开

    公开(公告)号：US20240082536A1

    公开(公告)日：2024-03-14

    申请号：US18236195

    申请日：2023-08-21

    申请人： Incept, LLC

    发明人： Brandon Yee ,  Ashoor Shahbazi Yourgenlow ,  Yi Yang ,  Farhad Khosravi ,  Joseph Rimsa

    IPC分类号： A61M25/00

    CPC分类号： A61M25/0012 ,  A61M25/0013 ,  A61M25/0147

    摘要： A catheter is provided comprising localized regions of modified flexibility. The regions of modified flexibility may comprise a softened inner liner, for example softened via stretching the inner liner or disposing a plurality of holes in the inner liner, to modify the bending stiffness and/or tensile stiffness of the catheter. The catheter may further include an axially extending filament that at least partially overlaps the softened portion of the inner liner. The axially extending filament may include an anchoring section to anchor the at least one axially extending filament in a section of the catheter that includes the helical coil.

    Vacuum transfer tool for extendable catheter
    39.
    发明授权
    Vacuum transfer tool for extendable catheter 有权

    公开(公告)号：US11471582B2

    公开(公告)日：2022-10-18

    申请号：US16503886

    申请日：2019-07-05

    申请人： INCEPT, LLC

    发明人： Brandon Yee

    IPC分类号： A61M1/00 ,  A61M39/22 ,  A61M25/00 ,  A61M25/09

    摘要： An aspiration catheter is provided including a proximal section and a distal section extendable through the proximal section. A vacuum transfer tool may be coupled to a proximal end of the proximal section. The vacuum transfer tool may include a proximal transfer tube and a distal transfer tube, each having an aspiration port in communication with a vacuum source. The proximal transfer tube may be removably received within a proximal end of the distal transfer tube. The proximal transfer tube may maintain a vacuum around the proximal end of the distal section of the catheter such that when the distal section is removed by decoupling the proximal and distal transfer tubes, the vacuum within the distal transfer tube and proximal section of the catheter is maintained, preventing the escape of any clots.