公开(公告)号：US10006443B1

公开(公告)日：2018-06-26

申请号：US14879398

申请日：2015-10-09

Applicant: Peter V. Vorobieff ,  Nima Fathi ,  Andrea A. Mammoli ,  Vakhtang Putkaradze ,  Michael Chi ,  Seyed Sobhan Aleyasin ,  Francois Gay-Balmaz

Inventor： Peter V. Vorobieff ,  Nima Fathi ,  Andrea A. Mammoli ,  Vakhtang Putkaradze ,  Michael Chi ,  Seyed Sobhan Aleyasin ,  Francois Gay-Balmaz

IPC: B23P15/26 ,  F03G6/04 ,  F24J2/00

CPC classification number: F03G6/045 ,  F24S20/61 ,  Y02B10/20 ,  Y02E10/465

Abstract: The present invention provides a self-supporting chimney apparatus. The chimney apparatus having at least one inflatable compartment. In some embodiments, the chimney apparatus may have a plurality of toroidal compartments, with the dimensions of the toroidal compartments calculated to maximize the structural integrity of the chimney apparatus, and with the pressure in the compartments dynamically adjusted to minimize deflection under wind loading. The self-supporting chimney apparatus may be used to construct an improved solar updraft tower, with the shape of the tower, the greenhouse surrounding its base, and the ground under the greenhouse optimized together to minimize energy losses. The efficiency of the power plant based on the design is further enhanced by combining solar thermal energy generation with photovoltaic energy generation and utilizing the waste heat of the latter.

公开(公告)号：US09981003B2

公开(公告)日：2018-05-29

申请号：US15038557

申请日：2014-11-25

Applicant: STC.UNM

Inventor： Jeff Wade Hill

IPC: A61K38/06 ,  C07K5/097 ,  C07K14/715 ,  A61K45/06 ,  A61K38/00

CPC classification number: A61K38/06 ,  A61K38/00 ,  A61K45/06 ,  C07K5/0823 ,  C07K14/7158

Abstract: The present invention provides a novel class of medicament based on CXCR antagonistic peptides. Among other things, the present invention provides peptides, compositions and methods for treating diseases, disorders and conditions in which a CXCR mediated pathway is implicated. Compositions and methods for effective treatment of inflammation, stroke, traumatic brain injury, pancreatic cancer, and others are provided.

公开(公告)号：US20180143138A1

公开(公告)日：2018-05-24

申请号：US15568029

申请日：2016-04-20

Applicant: STC.UNM

Inventor： Andrew P Shreve ,  Steven Wayde Graves ,  Bruce S Edwards ,  Jaime Javier Juarez

IPC: G01N21/64 ,  G01J3/02 ,  G01N15/14 ,  G01J3/28 ,  G01N15/02

CPC classification number: G01N21/6486 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0291 ,  G01J3/0294 ,  G01J3/2823 ,  G01J2003/2826 ,  G01N15/0211 ,  G01N15/14 ,  G01N15/147 ,  G01N2015/1006

Abstract: A method to simultaneously detect emission intensity or images at multiple distinct emission wavelengths in the analysis of parallel sample streams in a flow-based analysis system and apparatus for performing the described method.

公开(公告)号：US20180021357A1

公开(公告)日：2018-01-25

申请号：US15691977

申请日：2017-08-31

Applicant: Ball State Innovation Corporation ,  STC.UNM

Inventor： Susan A. McDowell ,  Robert E. Sammelson ,  Larry A. Sklar ,  Mark K. Haynes

IPC: A61K31/635

CPC classification number: A61K31/635

Abstract: The present disclosure relates to molecules that function as selective modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases and, in particular, CDC42 GTPase, and their use to treat bacterial infection including systemic infection from sources such as Staphylococcus aureus and Streptococcus pyogenes.

公开(公告)号：US09859677B1

公开(公告)日：2018-01-02

申请号：US15488088

申请日：2017-04-14

Applicant: STC.UNM

Inventor： Ladan Arissian ,  Jean-Claude Diels

IPC: G01N21/41 ,  H01S3/11 ,  H01S3/0957 ,  H01S3/106

CPC classification number: H01S3/1112 ,  G01N21/41 ,  G01N21/4133 ,  G01N2201/06113 ,  H01S3/0014 ,  H01S3/0957 ,  H01S3/105 ,  H01S3/1062 ,  H01S3/1106

Abstract: Apparatus, systems, and methods of generating multi combs can be used in a variety of applications. In various embodiments, a passive resonator can be disposed in the laser cavity of a mode-locked laser to generate a nested frequency comb. The passive resonator can be a sample under investigation, where a characteristic of the sample is determined using the generated nested frequency comb. Additional apparatus, systems, and methods are disclosed.

公开(公告)号：US09837240B1

公开(公告)日：2017-12-05

申请号：US14742634

申请日：2015-06-17

Applicant: Edl Schamiloglu ,  Mikhail I. Fuks

Inventor： Edl Schamiloglu ,  Mikhail I. Fuks

IPC: H01J23/20 ,  H01J25/50

CPC classification number: H01J23/20 ,  H01J23/02 ,  H01J25/50

Abstract: The present invention provides a relativistic magnetron including an anode with an entrant channel, the channel having an input end, an output end and a dimensional discontinuity between the ends. The channel is connected to the magnetron and has an anode defining an interaction space located between the dimensional discontinuity and output end. Also provided is a cathode, located upstream, a spaced distance away from the interaction space towards the input end, the cathode is adapted to send an electron beam into the interaction space where the electron beam forms a virtual cathode in the interaction space.

公开(公告)号：US09827446B2

公开(公告)日：2017-11-28

申请号：US15388201

申请日：2016-12-22

Applicant: STC.UNM ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Shuang Luan ,  Lijun Ma ,  Zhe Chen

IPC: A61N5/00 ,  A61N5/10 ,  A61B6/00

CPC classification number: A61N5/1084 ,  A61B6/4085 ,  A61N5/10 ,  A61N5/1031 ,  A61N5/1065 ,  A61N5/1067 ,  A61N5/1071 ,  A61N5/1081 ,  A61N2005/1074

Abstract: Photon-based radiosurgery is widely used for treating local and regional tumors. The key to improving the quality of radiosurgery is to increase the dose falloff rate from high dose regions inside the tumor to low dose regions of nearby healthy tissues and structures. Dynamic photon painting (DPP) further increases dose falloff rate by treating a target by moving a beam source along a dynamic trajectory, where the speed, direction and even dose rate of the beam source change constantly during irradiation. DPP creates dose gradient that rivals proton Bragg Peak and outperforms Gamma Knife® radiosurgery.

公开(公告)号：US20170253489A1

公开(公告)日：2017-09-07

申请号：US15515960

申请日：2015-09-30

Applicant: Alexey Serov ,  Plamen B Atanassov ,  Nikolai Kalugin ,  Liliya V Frolova

Inventor： Alexey Serov ,  Plamen B Atanassov ,  Nikolai Kalugin ,  Liliya V Frolova

IPC: B01D15/08 ,  G01N30/02 ,  G01N30/14 ,  G01N30/62 ,  C01B31/00

CPC classification number: B01D15/08 ,  C01B32/182 ,  C01B32/196 ,  C07B2200/09 ,  C07C51/47 ,  C07D207/08 ,  G01N30/02 ,  G01N30/14 ,  G01N30/62 ,  G01N2030/027 ,  G01N2030/143 ,  G01N2030/146 ,  G01N2030/621 ,  G01N2030/623 ,  C07C57/30

Abstract: A variety of inorganic-organic hybrid materials and various methods for preparing and using the same are described. The hybrid materials are graphene or graphitic materials populated with organic molecules and may have a variety of surface defects, pits or three-dimensional architecture, thereby increasing the surface area of the material. The hybrid materials may take the form of three dimensional graphene nanosheets (3D GNS). If the organic molecules are enantiospecific molecules, the hybrid materials can be used for chiral separation of racemic mixtures.

公开(公告)号：US09744292B2

公开(公告)日：2017-08-29

申请号：US14544032

申请日：2014-11-17

Applicant: STC.UNM

Inventor： Mark Hauswald

IPC: A61M5/14 ,  A61M5/142 ,  A61M5/315 ,  A61M5/168

CPC classification number: A61M5/14216 ,  A61M5/1422 ,  A61M5/16809 ,  A61M5/31535 ,  A61M5/31548 ,  A61M2202/048

Abstract: A mechanical infusion pump device for injecting medication into a patient's IV, includes an IV reservoir and a syringe communicated to the IV reservoir and having a syringe plunger which is moved in a first direction against a mechanical biasing element by engagement with a manually operable, independently movable filling plunger to fill the syringe with fluid medication. The mechanical biasing element is provided for exerting bias on the syringe plunger in a second syringe-discharging direction to dispense medication from the syringe into the patient's IV when the filling plunger is released. Only a calibrated amount of medicine can be discharged to the patent's IV over time as determined by calibration of the biasing element and a metering element located between the syringe and the patient's IV for a given viscosity of the medication.

公开(公告)号：US09717783B2

公开(公告)日：2017-08-01

申请号：US13946562

申请日：2013-07-19

Applicant: STC.UNM

Inventor： Bryce Chackerian ,  David S. Peabody ,  Ebenezer Tumban

IPC: A61K39/12 ,  A61K39/00

CPC classification number: A61K39/12 ,  A61K2039/5258 ,  A61K2039/58 ,  C12N2710/20034 ,  C12N2795/18023 ,  C12N2795/18071

Abstract: The invention provides immunotherapeutic and prophylactic bacteriophage viral-like particle (VLPs) which are useful in the treatment and prevention of human papillomavirus (HPV) infections and related disorders, including cervical cancer and persistent infections associated with HPV. Related compositions (e.g. vaccines), nucleic acid constructs, and therapeutic methods are also provided. VLPs and related compositions of the invention induce high titer antibody responses against HPV L2 and protect against HPV challenge in vivo. VLPs, VLP-containing compositions, and therapeutic methods of the invention induce an immunogenic response against HPV infection, confer immunity against HPV infection, protect against HPV infection, and reduce the likelihood of infection by HPV infection.