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公开(公告)号：US11879470B2
公开(公告)日：2024-01-23
申请号：US17057357
申请日：2019-05-31
Applicant: Micromass UK Limited
Inventor： Cedric Marsh , Peter Carney , Jason Lee Wildgoose , David Wallis , Paul McIver , Soji Chummar , George Andreas Antoniades , Dipesh Mistry
CPC classification number: F04D19/042 , F04D29/122 , F04D29/701 , H01J49/24 , H01J49/405
Abstract: A mass spectrometer comprising: a vacuum housing comprising a first vacuum chamber having a first gas exhaust port; a gas pump (1700) having a first gas inlet port connected to the first gas exhaust port (H1) by a first gas conduit for evacuating the first vacuum chamber; and a first apertured cover (2010) arranged over the first gas exhaust port (H1) or first gas inlet port, or in the first gas conduit therebetween.
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公开(公告)号：US11817303B2
公开(公告)日：2023-11-14
申请号：US16636877
申请日：2018-07-26
Applicant: Micromass UK Limited
Inventor： Anatoly Verenchikov , Mikhail Yavor
CPC classification number: H01J49/403 , H01J49/0031 , H01J49/025 , H01J49/061 , H01J49/164 , H01J49/401 , H01J49/405 , H01J49/406 , H01J49/4245
Abstract: Improved pulsed ion sources and pulsed converters are proposed for multi-pass time-of-flight mass spectrometer, either multi-reflecting (MR) or multi-turn (MT) TOF. A wedge electrostatic field (45) is arranged within a region of small ion energy for electronically controlled tilting of ion packets (54) time front. Tilt angle γ of time front (54) is strongly amplified by a post-acceleration in a flat field (48). Electrostatic deflector (30) downstream of the post-acceleration (48) allows denser folding of ion trajectories, whereas the injection mechanism allows for electronically adjustable mutual compensation of the time front tilt angle, i.e. γ=0 for ion packet in location (55), for curvature of ion packets, and for the angular energy dispersion. The arrangement helps bypassing accelerator (40) rims, adjusting ion packets inclination angles α2 and what is most important, compensating for mechanical misalignments of the optical components.
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公开(公告)号：US09899202B2
公开(公告)日：2018-02-20
申请号：US15169952
申请日：2016-06-01
Applicant: PERKINELMER HEALTH SCIENCES, INC.
Inventor： Anthony Chiappetta , Urs Steiner , Keith Ferrara
CPC classification number: H01J49/405 , H01J49/02 , H01J49/24 , H01J49/40
Abstract: Certain embodiments described herein are directed to time of flight tubes comprising a cylindrical tube comprising an inner surface and an outer surface, the cylindrical tube comprising an effective thickness and sized and arranged to couple to and support a reflectron assembly inside the cylindrical tube. In some configurations, the cylindrical tube further comprises a conductive material disposed on the inner surface of the cylindrical tube, the conductive material present in an effective amount to provide a field free region for ions when the conductive material is charged.
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公开(公告)号：US09892902B2
公开(公告)日：2018-02-13
申请号：US15334559
申请日：2016-10-26
Applicant: SHIMADZU CORPORATION
Inventor： Osamu Furuhashi , Hideaki Izumi
CPC classification number: H01J49/401 , H01J49/062 , H01J49/10 , H01J49/405
Abstract: Used as an ion beam guiding unit for introducing primary ions to the surface of the sample is an ion optical system of reflectron TOFMS for achieving time focusing including an orthogonal acceleration unit for accelerating the ions in the orthogonal direction, a flight space of a non-electric field, and an ion reflector for forming a reflecting electric field. A dual stage type is used as the ion reflector to superimpose the correction potential showing a predetermined non-linear potential distribution on the potential having a linear gradient of a uniform electric field at the side deeper than the second order focusing position that fulfills the Mamyrin solution, thereby correcting the temporal spread of ion packets emitted from the orthogonal acceleration unit until the deviation of third or higher order in energy, achieving high time focusing.
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公开(公告)号：US09887075B2
公开(公告)日：2018-02-06
申请号：US14895520
申请日：2014-05-28
Applicant: Micromass UK Limited
Inventor： John Brian Hoyes
CPC classification number: H01J49/405 , H01J49/062 , H01J49/063 , H01J49/065 , H01J49/40 , H01J49/4215 , H01J49/4225 , H01J49/4235
Abstract: A device for manipulating charged particles using an axial electric field as they travel along a longitudinal axis of the device is disclosed. The method comprises providing an outer electrode for generating an electric field and providing a plurality of inner electrodes that are separated by gaps of different lengths. The electric field generated by the outer electrode penetrates the gaps between the inner electrodes and the gaps are selected such that the desired potential profile is arranged along the longitudinal axis in order to manipulate the charged particles in the desired manner.
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Patent Agency Ranking
公开(公告)号：US09865445B2
公开(公告)日：2018-01-09
申请号：US14776613
申请日：2013-03-14
Applicant: LECO Corporation
Inventor： Anatoly N. Verenchikov , Mikhail I. Yavor
CPC classification number: H01J49/406 , H01J49/067 , H01J49/405
Abstract: To improve spatial and energy acceptance of multi-reflecting time-of-flight, open traps, and electrostatic trap analyzers, a novel ion mirror is disclosed. Incorporation of immersion lens between ion mirrors allows reaching the fifth order time per energy focusing simultaneously with the third order time per spatial focusing including energy-spatial cross terms. Preferably the analyzer has hollow cylindrical geometry for extended flight path. The time-of-flight analyzer preferably incorporates spatially modulated ion mirror field for isochronous ion focusing in the tangential direction.
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公开(公告)号：US09583327B2
公开(公告)日：2017-02-28
申请号：US14407531
申请日：2013-06-12
Applicant: C&E RESEARCH, INC.
Inventor： Timothy Cornish , Scott Ecelberger
CPC classification number: H01J49/405 , H01J49/0013 , H01J49/025
Abstract: A miniature time-of-flight mass spectrometer (TOF-MS) was developed for a NASA/ASTID program beginning 2008. The primary targeted application for this technology is the detection of non-volatile (refractory) and biological materials on landed planetary missions. Both atmospheric and airless bodies are potential candidate destinations for the purpose of characterizing mineralogy, and searching for evidence of existing or extant biological activity.
Abstract translation: 从2008年开始，为NASA / ASTID计划开发了一种微型飞行时间质谱仪（TOF-MS）。该技术的主要目标应用是检测着陆行星任务中的非挥发性（难熔）和生物材料。 大气和无气体都是潜在的候选目的地，用于表征矿物学，并寻找现有或现存生物活性的证据。
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38.发明申请公开(公告)号：US20160148796A1
公开(公告)日：2016-05-26
申请号：US14945305
申请日：2015-11-18
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor： Alexander A. MAKAROV
CPC classification number: H01J49/405 , H01J49/4245 , H01J49/425 , H01J49/427
Abstract: A charged particle analyzer apparatus comprising two opposing ion mirrors each mirror comprising inner and outer field-defining electrode systems elongated along an axis z, the outer system surrounding the inner, whereby when the electrode systems are electrically biased the mirrors create an electrical field comprising opposing electrical fields along z; and at least one arcuate focusing lens for constraining the arcuate divergence of a beam of charged particles within the analyzer whilst the beam orbits around the axis z, the analyzer further comprising a disc having two faces at least partly spanning the space between the inner and outer field defining electrode systems and lying in a plane perpendicular to the axis z, the disc having resistive coating upon both faces. A mass spectrometer system comprising a plurality of the charged particle analyzers arranged as a parallel array.
Abstract translation: 一种带电粒子分析仪装置，包括两个相对的离子镜，每个反射镜包括沿着轴线z延伸的内部和外部场限定电极系统，外部系统围绕内部，由此当电极系统被电偏置时，反射镜产生电场，包括相对 z电场; 以及至少一个弧形聚焦透镜，用于约束分析器内的带电粒子束的弓形发散，同时光束围绕轴线z绕着轴线z移动，分析器还包括具有至少部分跨越内部和外部之间的空间的两个面的盘 场定义电极系统并且位于垂直于轴线z的平面中，该盘在两个面上具有电阻涂层。 一种质谱仪系统，包括多个被布置成平行阵列的带电粒子分析器。
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公开(公告)号：US20160126083A1
公开(公告)日：2016-05-05
申请号：US14895520
申请日：2014-05-28
Applicant: MICROMASS UK LIMITED
Inventor： John Brian HOYES
CPC classification number: H01J49/405 , H01J49/062 , H01J49/063 , H01J49/065 , H01J49/40 , H01J49/4215 , H01J49/4225 , H01J49/4235
Abstract: A device for manipulating charged particles using an axial electric field as they travel along a longitudinal axis of the device is disclosed. The method comprises providing an outer electrode for generating an electric field and providing a plurality of inner electrodes that are separated by gaps of different lengths. The electric field generated by the outer electrode penetrates the gaps between the inner electrodes and the gaps are selected such that the desired potential profile is arranged along the longitudinal axis in order to manipulate the charged particles in the desired manner.
Abstract translation: 公开了一种用于在沿着装置的纵向轴线行进时使用轴向电场来操纵带电粒子的装置。 该方法包括提供用于产生电场的外部电极并提供由不同长度的间隙分开的多个内部电极。 由外部电极产生的电场穿过内部电极之间的间隙，并且选择间隙，使得期望的电位分布沿着纵向轴线布置，以便以期望的方式操纵带电粒子。
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公开(公告)号：US20160035558A1
公开(公告)日：2016-02-04
申请号：US14776613
申请日：2013-03-14
Applicant: LECO CORPORATION
Inventor： Anatoly N. Verenchikov , Mikhail I. Yavor
CPC classification number: H01J49/406 , H01J49/067 , H01J49/405
Abstract: To improve spatial and energy acceptance of multi-reflecting time-of-flight, open traps, and electrostatic trap analyzers, a novel ion mirror is disclosed. Incorporation of immersion lens between ion mirrors allows reaching the fifth order time per energy focusing simultaneously with the third order time per spatial focusing including energy-spatial cross terms. Preferably the analyzer has hollow cylindrical geometry for extended flight path. The time-of-flight analyzer preferably incorporates spatially modulated ion mirror field for isochronous ion focusing in the tangential direction.
Abstract translation: 为了提高多反射飞行时间，开路陷阱和静电捕获分析仪的空间和能量接受度，公开了一种新型离子镜。 在离子镜之间并入浸没透镜允许每次能量聚焦达到第五阶时间，同时每个空间聚焦的三阶时间同时包括能量 - 空间交叉项。 优选地，分析器具有用于延伸飞行路径的中空圆柱形几何形状。 飞行时间分析仪优选地在切向方向上并入空间调制的离子镜场用于同步离子聚焦。
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