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51 条记录 (耗时 0.026 秒)

    Polylactic acid scleral plug
    32.
    发明授权
    Polylactic acid scleral plug 失效
    聚乳酸巩膜塞

    公开(公告)号：US06488938B1

    公开(公告)日：2002-12-03

    申请号：US09475371

    申请日：1999-12-30

    申请人： Yuichiro Ogura ,  Noriyuki Kunou ,  Atsutoshi Ota

    发明人： Yuichiro Ogura ,  Noriyuki Kunou ,  Atsutoshi Ota

    IPC分类号： A61K900

    CPC分类号： A61K9/0051 ,  Y10S514/954 ,  Y10S514/955

    摘要： A scleral plug which releases a drug accurately in a specified amount. The scleral plug is formed from a blend of a high-molecular weight polylactic acid having a molecular weight of 40,000 or higher and a low-molecular weight polylactic acid having a molecular weight of 40,000 or lower, and contains a drug for treating or preventing a vitreoretinal disease. The high-molecular weight polylactic acid and the low-molecular weight polylactic acid are in a blending ratio of preferably 90/10 to 50/50, more preferably 90/10 to 70/30, and most preferably 80/20. The molecular weight of the high-molecular weight polylactic acid is preferably 40,000 to 200,000. The molecular weight of the low-molecular weight polylactic acid is preferably 3,000 to 40,000, and more preferably 5,000 to 20,000. The drug is, for example, an antiulcer agent, an antiviral agent, an anti-inflammatory agent, an antifungal agent or an antimicrobial.

    摘要翻译： 一种巩固的塞子，以一定的量精确释放药物。 巩膜塞由分子量为40,000以上的高分子量聚乳酸和分子量为40,000以下的低分子量聚乳酸的共混物形成，并含有用于治疗或预防 玻璃体视网膜疾病 高分子量聚乳酸和低分子量聚乳酸的共混比优选为90/10〜50/50，更优选为90/10〜70/30，最优选为80/20。 高分子量聚乳酸的分子量优选为40,000〜200,000。 低分子量聚乳酸的分子量优选为3,000〜40,000，更优选为5,000〜20,000。 该药物是例如抗溃疡剂，抗病毒剂，抗炎剂，抗真菌剂或抗菌剂。

    Drug preparation applicable to oral mucosa
    36.
    发明授权
    Drug preparation applicable to oral mucosa 失效
    适用于口腔MUCOSA的药物制剂

    公开(公告)号：US5137729A

    公开(公告)日：1992-08-11

    申请号：US472933

    申请日：1990-01-31

    申请人： Takamasa Kuroya ,  Yuichi Inoue

    发明人： Takamasa Kuroya ,  Yuichi Inoue

    IPC分类号： A61K9/70 ,  A61K9/00 ,  A61L15/44 ,  A61L15/58

    CPC分类号： A61K9/006 ,  Y10S514/944 ,  Y10S514/953 ,  Y10S514/955

    摘要： A drug preparation applicable to the oral mucosa is disclosed, comprising a soft adhesive film containing a systemic drug, the adhesive film comprising a homogeneous mixture comprising a vinyl acetate homopolymer, an acrylic acid polymer, and a cellulose derivative capable of being dissolved in or swollen with water and a lower alcohol. The drug preparation is less causative of an adverse feeling in the oral cavity on use, excellent in shape retention on water absorption, and adhesive to the oral mucosa for an extended period of time, thereby achieving a stable administration of a systemic drug for a long time.

    Hydrogen separation and electricity generation using novel three-component membrane
    39.
    发明授权
    Hydrogen separation and electricity generation using novel three-component membrane 失效
    使用新型三组分膜进行氢分离和发电

    公开(公告)号：US4795536A

    公开(公告)日：1989-01-03

    申请号：US70622

    申请日：1987-07-06

    申请人： Ping Young ,  Anthony J. Polak

    发明人： Ping Young ,  Anthony J. Polak

    IPC分类号： C01B3/50 ,  C25B5/00 ,  H01M8/10 ,  C25B1/02 ,  C25B9/00

    CPC分类号： H01M8/1044 ,  C01B3/503 ,  C25B5/00 ,  H01M8/1023 ,  H01M8/1048 ,  C01B2203/0405 ,  C01B2203/048 ,  Y02E60/566 ,  Y10S514/886 ,  Y10S514/955 ,  Y10S514/963 ,  Y10S514/964 ,  Y10S514/965

    摘要： Apparatus and method for performing an electrochemical process involving hydrogen and gaseous compounds capable of dissociating into or combining with hydrogen ions using a solid electrolyte concentraton cell. Specific applications are fuel cells for producing an electrical current and separation of hydrogen from a gaseous mixture. A novel solid electrolyte membrane is used which comprises a three-component blend prepared by admixing an organic polymer, such as poly(vinyl alcohol), with an inorganic comound, such as a phosphoric acid, and a polyorganic acid, such as poly(acrylic acid), in a mutually miscible solvent. For increased strength, a membrane may be composited with or attached to a porous support. In one embodiment, electrically conductive particles with catalyst are partially embedded in the membrane to form a hydrogen separating device.

    摘要翻译： 用于使用固体电解质浓缩细胞进行能够解离成氢离子或与氢离子组合的氢和气态化合物的电化学方法的装置和方法。 具体应用是用于产生电流和从气体混合物中分离氢的燃料电池。 使用新颖的固体电解质膜，其包括通过将有机聚合物（例如聚（乙烯醇））与无机化合物如磷酸和聚有机酸（例如聚（丙烯酸））混合而制备的三组分共混物 酸），在相互混溶的溶剂中。 为了增加强度，膜可以与多孔载体复合或连接到多孔载体上。 在一个实施方案中，具有催化剂的导电颗粒部分地嵌入膜中以形成氢分离装置。

    Calcium phosphate cements and methods for using the same
    40.
    发明授权
    Calcium phosphate cements and methods for using the same 有权
    磷酸钙水泥及其使用方法

    公开(公告)号：US08419803B2

    公开(公告)日：2013-04-16

    申请号：US11189555

    申请日：2005-07-25

    申请人： Brent R. Constantz ,  David Delaney ,  Duran Yetkinler

    发明人： Brent R. Constantz ,  David Delaney ,  Duran Yetkinler

    IPC分类号： A61K9/14 ,  A61K33/42 ,  A61K33/06 ,  A61F2/28 ,  C04B12/02 ,  C04B7/00

    CPC分类号： A61L27/12 ,  Y10S514/951 ,  Y10S514/955

    摘要： Methods and compositions for producing flowable compositions, e.g. pastes, that set into calcium phosphate products are provided. In the subject methods, dry reactants that include a calcium source and a phosphate source are combined with a setting fluid to produce the flowable composition. A feature of the subject methods is that the dry reactants include a particulate calcium and/or phosphate reactant having a mean particle size of less than about 8 μm and narrow size distribution. Also provided are the compositions themselves as well as kits for use in practicing the subject methods. The subject methods and compositions produced thereby find use in a variety of applications, including the repair of hard tissue defects, e.g., bone defects.

    摘要翻译： 用于生产可流动组合物的方法和组合物，例如 提供了设置成磷酸钙产品的糊剂。 在本发明方法中，包括钙源和磷酸盐源的干燥反应物与固化流体组合以产生可流动组合物。 本发明方法的特征在于干燥的反应物包括平均粒径小于约8μm并且尺寸分布窄的粒状钙和/或磷酸盐反应物。 还提供了组合物本身以及用于实践本发明方法的试剂盒。 由此产生的主题方法和组合物可用于各种应用，包括修复硬组织缺陷，例如骨缺损。