Method to trigger RNA interference
    42.
    发明授权
    Method to trigger RNA interference 有权
    触发RNA干扰的方法

    公开(公告)号:US08030473B2

    公开(公告)日:2011-10-04

    申请号:US11334776

    申请日:2006-01-06

    摘要: A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens.

    摘要翻译: 描述了在体内产生siRNA的方法,以及在该方法中有用的构建体和组合物。 该方法不依赖于使用含有反向重复或双重启动子的DNA或合成构建体,以形成完整或大部分双链RNA。 相反,该方法取决于产生单链RNA转录物的构建体,并利用内源或体内产生的miRNA或siRNA来引发siRNA的产生。 miRNA或siRNA指导转录物的切割,并设置用于生产与构建体内的起始切割位点相邻编码的siRNA(通常长度为21个核苷酸)的寄存器。 该方法导致相对于起始切割位点具有可预测大小和寄生(相)的siRNA的特异性形成。 该方法可用于在体内产生特异性siRNA以灭活或抑制一种或多种靶基因或其他实体,例如病原体。

    Heat-activated heat-pump systems including integrated expander/compressor and regenerator
    43.
    发明授权
    Heat-activated heat-pump systems including integrated expander/compressor and regenerator 有权
    热活化热泵系统,包括集成的膨胀机/压缩机和再生器

    公开(公告)号:US07971449B2

    公开(公告)日:2011-07-05

    申请号:US11660170

    申请日:2005-08-15

    IPC分类号: F25B13/00

    摘要: Heat-activated heat-pump systems and related methods are disclosed that include a power cycle coupled to a vapor-compression refrigeration cycle both utilizing the same working fluid. The power cycle comprises a boiler, an expander receiving superheated vapor and producing work from the superheated vapor, a condenser, and a pump. A regenerator conducts a first stream of working fluid from the pump to the boiler and a second stream of the working fluid from the expander to the condenser while transferring heat from the second stream to the first stream. The refrigeration cycle comprises a compressor that compresses the working fluid from the evaporator and delivers the compressed working fluid to a condenser. The expander and compressor are coupled together such that at least a portion of the work produced by the expander is utilized for running the compressor.

    摘要翻译: 公开了热激活热泵系统和相关方法,其包括耦合到使用相同工作流体的蒸气压缩制冷循环的动力循环。 动力循环包括锅炉,膨胀器接收过热蒸汽并从过热蒸汽产生工作,冷凝器和泵。 再生器将来自泵的第一工作流体流引导至锅炉,并且将第二流的工作流体从膨胀器传导到冷凝器,同时将热量从第二流传递到第一流。 制冷循环包括压缩机,其压缩来自蒸发器的工作流体并将压缩的工作流体输送到冷凝器。 膨胀机和压缩机联接在一起,使得由膨胀机产生的工件的至少一部分用于运行压缩机。

    Formaldehyde-free adhesives and lignocellulosic composites made from the adhesives
    45.
    发明授权
    Formaldehyde-free adhesives and lignocellulosic composites made from the adhesives 有权
    不含甲醛的粘合剂和由粘合剂制成的木质纤维复合材料

    公开(公告)号:US07722712B2

    公开(公告)日:2010-05-25

    申请号:US10586623

    申请日:2005-01-19

    申请人: Kaichang Li

    发明人: Kaichang Li

    IPC分类号: C09J197/00 C09J189/00

    摘要: A first variant of an adhesive composition for making a lignocellulosic composite includes soy protein and/or lignin; at least one substantially formaldehyde-free curing agent that includes at least one amine, amide, imine, imide, or nitrogen-containing heterocyclic functional group that can react with at least one functional group of the soy protein; and at least one compound selected from a boron compound, a group IA oxide or hydroxide, or a group IIA oxide or hydroxide. A second variant of an adhesive composition includes a first component selected from soy protein and/or lignin; and at least one substantially formaldehyde-free curing agent selected from a reaction product of epichlorohydrin with ethylenediamine, a reaction product of epichlorohydrin with bis-hexamethylenetriamine, or a reaction product of epichlorohydrin with hexamethylenediamine.

    摘要翻译: 用于制备木质纤维素复合物的粘合剂组合物的第一变体包括大豆蛋白和/或木质素; 至少一种基本上不含甲醛的固化剂,其包含可与至少一种大豆蛋白官能团反应的至少一种胺,酰胺,亚胺,酰亚胺或含氮杂环官能团; 和至少一种选自硼化合物,IA族氧化物或氢氧化物或IIA族氧化物或氢氧化物的化合物。 粘合剂组合物的第二变体包括选自大豆蛋白和/或木质素的第一组分; 和至少一种选自表氯醇与乙二胺的反应产物,表氯醇与双六亚甲基三胺的反应产物或表氯醇与六亚甲基二胺的反应产物的基本上不含甲醛的固化剂。

    Methods and apparatus for incomplete modular arithmetic
    48.
    发明授权
    Methods and apparatus for incomplete modular arithmetic 失效
    不完全模算法的方法和装置

    公开(公告)号:US07080109B2

    公开(公告)日:2006-07-18

    申请号:US09895835

    申请日:2001-06-29

    IPC分类号: G06F7/38

    CPC分类号: G06F7/72 G06F7/722 G06F7/728

    摘要: Methods and apparatus for modular arithmetic operations with respect to a modulus p include representing operands as a series of s w-bit numbers, wherein s = ⌈ k w ⌉ . Operations are executed word by word and a carry, borrow, or other bit or word is obtained from operations on most significant words of the operands. Depending on the value of this bit or word, an operation-specific correction factor is applied. Cryptographic systems include computer executable instructions for such methods. Bit-level operations are generally avoided and the methods and apparatus are applicable to systems based on, for example, public-key cryptographic algorithms defined over the finite field GF(p).

    摘要翻译: 关于模数p的模运算的方法和装置包括将操作数表示为一系列w位数,其中 = 并且从操作数的最高有效字上的操作获得进位,借位或其他位或字。 根据该位或字的值,应用操作特定的校正因子。 加密系统包括用于这种方法的计算机可执行指令。 通常避免位级操作,并且该方法和装置适用于基于例如在有限域GF(p)上定义的公钥密码算法的系统。

      Concrete solar cell
      49.
      发明授权
      Concrete solar cell 失效
      混凝土太阳能电池

      公开(公告)号:US5415700A

      公开(公告)日:1995-05-16

      申请号:US166307

      申请日:1993-12-10

      摘要: An inexpensive, robust concrete solar cell (10) comprises a photovoltaic material embedded in and extending beyond the major surfaces (16 and 18) of a matrix layer (14). The matrix layer typically comprises a high strength, cementitious material, such as a macrodefect free cement. The photovoltaic material comprises particles (12) of high-resistivity single crystal silicon, typically ball milled from ingot sections unsuitable for slicing into silicon wafers. The ingot sections include unprecipitated dissolved oxygen that is electrically activated by a low temperature annealing process to produce n-type silicon, even in silicon crystals that include a p-type dopant. An aluminum sheet (28), positioned on the backside of the matrix layer, is briefly melted together with the silicon particles to produce a p-type aluminum-doped silicon region (22) that forms a pn junction with the n-type region (24) of the particle. The aluminum sheet also provides the electrical contact to the p-type regions. The front surface of the matrix layer, from which the n-portion of the silicon particle protrudes, is covered with a translucent indium tin oxide conductive layer (30) that provides electrical contacts to the n-portion of the pn junction and digitated electrode (32) for conducting current off the cell. A voltage is generated between the two conductive layers when light incident on the photovoltaic particle through the indium tin oxide conductive layer creates charge carriers.

      摘要翻译: 廉价,坚固的混凝土太阳能电池(10)包括嵌入并延伸到矩阵层(14)的主表面(16和18)之外的光伏材料。 基质层通常包括高强度的水泥质材料,例如无损坏的水泥。 光伏材料包括高电阻率单晶硅的颗粒(12),通常由不适于切片成硅晶片的锭块球磨成球形。 锭部分包括通过低温退火工艺电活化以产生n型硅的未沉淀的溶解氧,即使在包括p型掺杂剂的硅晶体中也是如此。 位于基质层背面的铝片(28)与硅颗粒一起短暂熔化,以产生与n型区形成pn结的p型铝掺杂硅区(22) 24)颗粒。 铝板还提供与p型区域的电接触。 硅颗粒的n部分从其突出的基质层的前表面被透明的氧化铟锡导电层(30)覆盖,该氧化铟锡导电层(30)提供与pn结的n部分和数字化电极 32)用于将电流从电池中导出。 当通过铟锡氧化物导电层入射到光伏颗粒上的光产生电荷载流子时,在两个导电层之间产生电压。