-
公开(公告)号:US20180155378A1
公开(公告)日:2018-06-07
申请号:US15576531
申请日:2016-05-26
Applicant: Monash University
Inventor: Philip Andrews , Melissa Werrett , Madleen Busse
IPC: C07F9/94 , A01N57/22 , A61K31/663 , A61K31/662 , A61L15/20 , A61L15/44 , A61L17/00 , A61L31/16 , A61L31/08 , A61L24/00 , A61K6/00 , C09D5/14
CPC classification number: C07F9/94 , A01N57/22 , A61K6/0067 , A61K31/662 , A61K31/663 , A61K33/245 , A61K33/42 , A61L15/20 , A61L15/44 , A61L17/005 , A61L24/0015 , A61L31/08 , A61L31/16 , A61L2300/404 , A61L2430/02 , C09D5/14
Abstract: Provided herein are organobismuth (III) phosphinate complexes, which comprise a phosphinate group and an aromatic carbocyclyl or aromatic heterocyclyl group. The complexes find use as antibacterial agents, and accordingly also provided herein are products, devices, compositions and materials comprising the complexes, for example medical products such as wound dressings and bandages.
-
公开(公告)号:US09828351B2
公开(公告)日:2017-11-28
申请号:US15321693
申请日:2015-06-26
Applicant: MONASH UNIVERSITY , UNIVERSITY OF SOUTH AUSTRALIA , CENTRAL ADELAIDE LOCAL HEALTH NETWORK INCORPORATED
Inventor: Bernard Luke Flynn , Luigi Aurelio , Carmen Vittoria Scullino , Bing Hui Wang , Stuart Maxwell Pitson , Melissa Rose Pitman
IPC: C07D271/113 , C07D285/08 , C07D419/12 , C07D285/135 , C07D271/07 , C07D277/56 , C07D271/10 , C07D413/12 , C07D413/10 , C07D271/107
CPC classification number: C07D285/08 , C07D271/06 , C07D271/07 , C07D271/10 , C07D271/107 , C07D271/113 , C07D277/56 , C07D285/135 , C07D413/10 , C07D413/12 , C07D419/12
Abstract: The present disclosure relates generally, but not exclusively, to compounds and their use as enzyme interacting agents, in particular, agents which interact with one or more enzymes in the sphingolipid biosynthesis pathway. The disclosure further relates to the use of such compounds as research tools, use in therapy, to compositions and agents comprising said compounds, and to methods of treatment using said compounds.
-
公开(公告)号:US09790603B2
公开(公告)日:2017-10-17
申请号:US14492793
申请日:2014-09-22
Applicant: MONASH UNIVERSITY
Inventor: Douglas MacFarlane , Alexey Izgorodin
IPC: C25B1/30 , C01B15/027
CPC classification number: C25B1/30 , C01B15/027
Abstract: The invention relates to a process for electrolysis comprising a cathode and an anode comprising a catalyst, both the cathode and anode at least partly immersed in an electrolyte, the process characterised in that the electrolyte at least partly inhibits further oxidation of a product formed at the anode. Typically the catalyst comprises one or more metal-(Group VIb) semiconductors, and one or more metal-(GroupVIb))-phosphorous species.
-
公开(公告)号:US20170137469A1
公开(公告)日:2017-05-18
申请号:US15301310
申请日:2015-04-01
Applicant: MONASH UNIVERSITY
Inventor: Jian LI , Roger NATION , Tony VELKOV , Philip THOMPSON , Kade D. ROBERTS
Abstract: The present invention relates to antimicrobial compounds and their uses, and in particular to peptide antibiotics which may be used in the treatment of bacterial infections such as Gram-negative bacterial infections, particularly those caused by multidrug-resistant (MDR) pathogens.
-
45.
公开(公告)号:US20170000878A1
公开(公告)日:2017-01-05
申请号:US15232736
申请日:2016-08-09
Applicant: MONASH UNIVERSITY
Inventor: Fasseli Joseph COULIBALY , Ashley Scott MANSELL , Rosemary Ann FFRENCH
Abstract: A stable immunogenic or vaccine composition comprising a complex or polyhedra comprising same comprising an antigen of a pathogen or other antigen against which a immune response is sought in a human or non-human animal subject and a polyhedrin protein derived from a cytoplasmic polyhedrosis virus (CPV). Delivery of the complex to a subject in substantially polyhedral form induces an immune response thereto. Methods of using same to elicit an immune response.
Abstract translation: 一种稳定的免疫原性或疫苗组合物,其包含复合物或多面体,其包含在人或非人动物受试者中寻求免疫应答的病原体或其他抗原的抗原和衍生自细胞质多角体病毒(CPV)的多角体蛋白 )。 复合物以基本上多面体形式递送到受试者,对其产生免疫应答。 使用它们引发免疫应答的方法。
-
公开(公告)号:US20160288090A1
公开(公告)日:2016-10-06
申请号:US15017737
申请日:2016-02-08
Inventor: Milton T. W. Hearn , Steven Langford , Kellie Louise Tuck , Simon Harris , Reinhard Ingemar Boysen , Victoria Tamara Perchyonok , Basil Danylec , Lachlan Schwarz , Jamil Chowdhury
IPC: B01J20/26 , B01D15/38 , B01J20/30 , C07C37/82 , C08F226/06
CPC classification number: B01J20/268 , A23L5/273 , A23V2002/00 , A61K31/74 , B01D15/3852 , B01J20/26 , B01J20/3057 , C07B63/00 , C07C37/82 , C08F226/06 , Y10T442/10
Abstract: The present invention provides methods of designing molecularly imprinted polymers (MIPs) which have applications in extracting bioactive compounds from a range of bioprocessing feedstocks and wastes. The present invention is further directed to MIPs designed by the methods of the present invention.
Abstract translation: 本发明提供了设计分子印迹聚合物(MIP)的方法,其可用于从一系列生物处理原料和废物中提取生物活性化合物。 本发明还涉及通过本发明的方法设计的MIP。
-
公开(公告)号:USD741941S1
公开(公告)日:2015-10-27
申请号:US29492435
申请日:2014-05-30
Applicant: Monash University
Designer: Mark Clement Armstrong , Kieran John , Arthur de Bono
-
公开(公告)号:US09090911B2
公开(公告)日:2015-07-28
申请号:US14304919
申请日:2014-06-14
Applicant: Monash University
Inventor: Scott Leslie O'Neill , Conor James McMeniman , Karyn Nicole Johnson , Elizabeth Ann McGraw , Luciano A. Moreira , Peter Anthony Ryan , Brian Herbert Kay , Jeremy Colin Brownlie
IPC: C12N1/00 , A01N63/00 , A01N65/00 , A61K39/00 , A61K39/02 , C12N15/87 , A01K67/033 , C12N15/01 , C12R1/01
CPC classification number: C12N15/87 , A01K67/033 , A01K67/0337 , A01K2227/70 , A01K2227/706 , A01K2267/02 , A01N63/00 , C12N15/01 , C12R1/01
Abstract: A modified arthropod, an arthropod-modifying bacterium, and use thereof as an agent for control of diseases transmitted by arthropods, particularly mosquitoes, is provided. More specifically, an isolated arthropod-adapted Wolbachia bacterium capable of modifying one or more biological properties of a mosquito host is provided. The modified arthropod may be characterized as having a shortened life-span, a reduced ability to transmit disease, a reduced susceptibility to a pathogen, a reduced fecundity, and/or a reduced ability to feed from a host, when compared to a corresponding wild-type arthropod.
Abstract translation: 提供了一种改良的节肢动物,节肢动物修饰细菌及其作为控制由节肢动物,特别是蚊子传播的疾病的药剂的用途。 更具体地,提供能够改变蚊子宿主的一种或多种生物学特性的分离的节肢动物适应的沃尔巴克氏杆菌细菌。 修饰的节肢动物的特征可以在于与相应的野生型相比具有缩短的寿命,降低的传播能力,降低的对病原体的易感性,降低的繁殖力和/或降低的从宿主进食的能力 型节肢动物
-
49.
公开(公告)号:US20150108006A1
公开(公告)日:2015-04-23
申请号:US14492793
申请日:2014-09-22
Applicant: MONASH UNIVERSITY
Inventor: Douglas MACFARLANE , Alexey IZGORODIN
IPC: C25B1/30
CPC classification number: C25B1/30 , C01B15/027
Abstract: The invention relates to a process for electrolysis comprising a cathode and an anode comprising a catalyst, both the cathode and anode at least partly immersed in an electrolyte, the process characterised in that the electrolyte at least partly inhibits further oxidation of a product formed at the anode. Typically the catalyst comprises one or more metal-(Group VIb) semiconductors, and one or more metal-(GroupVIb))-phosphorous species.
Abstract translation: 本发明涉及一种电解方法,包括阴极和阳极,其包括催化剂,阴极和阳极至少部分地浸入电解质中,该方法的特征在于电解质至少部分地抑制在 阳极。 通常,催化剂包含一种或多种金属 - (Ⅵb族)半导体和一种或多种金属 - (Ⅵb)) - 磷类。
-
公开(公告)号:US20140298501A1
公开(公告)日:2014-10-02
申请号:US14304919
申请日:2014-06-14
Applicant: Monash University
Inventor: Scott Leslie O'Neill , Conor James McMeniman , Karyn Nicole Johnson , Elizabeth Ann McGraw , Luciano A. Moreira , Peter Anthony Ryan , Brian Herbert Kay , Jeremy Colin Brownlie
IPC: C12N15/87 , A01K67/033
CPC classification number: C12N15/87 , A01K67/033 , A01K67/0337 , A01K2227/70 , A01K2227/706 , A01K2267/02 , A01N63/00 , C12N15/01 , C12R1/01
Abstract: A modified arthropod, an arthropod-modifying bacterium, and use thereof as an agent for control of diseases transmitted by arthropods, particularly mosquitoes, is provided. More specifically, an isolated arthropod-adapted Wolbachia bacterium capable of modifying one or more biological properties of a mosquito host is provided. The modified arthropod may be characterized as having a shortened life-span, a reduced ability to transmit disease, a reduced susceptibility to a pathogen, a reduced fecundity, and/or a reduced ability to feed from a host, when compared to a corresponding wild-type arthropod.
Abstract translation: 提供了一种改良的节肢动物,节肢动物修饰细菌及其作为控制由节肢动物,特别是蚊子传播的疾病的药剂的用途。 更具体地,提供能够改变蚊子宿主的一种或多种生物学特性的分离的节肢动物适应的沃尔巴克氏杆菌细菌。 修饰的节肢动物的特征可以在于与相应的野生型相比具有缩短的寿命,降低的传播能力,降低的对病原体的易感性,降低的繁殖力和/或降低的从宿主进食的能力 型节肢动物
-
-
-
-
-
-
-
-
-