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    SAMPLE PROCESSING UNITS, SYSTEMS, AND RELATED METHODS
    42.
    发明申请
    SAMPLE PROCESSING UNITS, SYSTEMS, AND RELATED METHODS 失效
    样品加工单元，系统和相关方法

    公开(公告)号：US20130059372A1

    公开(公告)日：2013-03-07

    申请号：US13595189

    申请日：2012-08-27

    申请人： Steven A. Hofstadler ,  Jared J. Drader ,  Jose R. Gutierrez ,  Paul J. Gleason ,  Rex O. Bare ,  Robert D. Miller ,  Jeffrey C. Smith

    发明人： Steven A. Hofstadler ,  Jared J. Drader ,  Jose R. Gutierrez ,  Paul J. Gleason ,  Rex O. Bare ,  Robert D. Miller ,  Jeffrey C. Smith

    IPC分类号： C12M1/40 ,  G01N9/00 ,  G01N33/00 ,  G01N1/00 ,  H01J49/26 ,  G01N27/04 ,  G01K13/12 ,  G01L19/00 ,  G01F23/00

    CPC分类号： G01N1/10 ,  G01N1/02 ,  G01N35/0098 ,  G01N35/025 ,  G01N2035/00524

    摘要： Sample processing units useful for mixing and purifying materials, such as fluidic materials are provided. A sample processing unit typically includes a container configured to contain a sample comprising magnetically responsive particles, and one or more magnets that are in substantially fixed positions relative to the container. A sample processing unit also generally includes a conveyance mechanism configured to convey the container to and from a position that is within magnetic communication with the magnet, e.g., such that magnetically responsive particles with captured analytes can be retained within the container when other materials are added to and/or removed from the container. Further, a sample processing unit also typically includes a rotational mechanism that is configured to rotate the container, e.g., to effect mixing of sample materials disposed within the container. Related carrier mechanisms, sample processing stations, systems, and methods are also provided.

    摘要翻译： 提供了用于混合和净化材料（如流体材料）的样品处理单元。 样品处理单元通常包括被配置为容纳包含磁响应颗粒的样品和相对于容器处于基本固定位置的一个或多个磁体的容器。 样品处理单元还通常包括输送机构，其构造成将容器输送到与磁体磁连通的位置，例如使得当添加其它材料时，具有捕获的分析物的磁响应颗粒可以保留在容器内 到和/或从容器中取出。 此外，样品处理单元还通常包括旋转机构，其被配置为旋转容器，例如以实现设置在容器内的样品材料的混合。 还提供了相关的载体机构，样品处理站，系统和方法。

    Multi-chambered retractable safety syringe
    44.
    发明授权
    Multi-chambered retractable safety syringe 有权
    多腔可伸缩安全注射器

    公开(公告)号：US08277422B2

    公开(公告)日：2012-10-02

    申请号：US12842885

    申请日：2010-07-23

    申请人： Richard B. Oliver ,  Daniel Thayer ,  Jeffrey Smith ,  Rex O. Bare

    发明人： Richard B. Oliver ,  Daniel Thayer ,  Jeffrey Smith ,  Rex O. Bare

    IPC分类号： A61M5/00

    CPC分类号： A61M5/3234 ,  A61M2005/3151 ,  A61M2005/3224 ,  A61M2005/323 ,  A61M2005/3242

    摘要： A retractable safety syringe may have a needle, needle holder, syringe body, and a plunger assembly. A proximal portion of the body and a piston of the plunger may define a vacuum chamber. The plunger assembly may comprise a distal piston and a proximal piston, with an intermediate chamber disposed between the two plungers. A vent through the syringe body pneumatically connects ambient air and the intermediate chamber allowing air to escape out of the intermediate chamber when a plunger assembly traversed toward the engaged position and allow air to be introduced into the intermediate chamber. A retraction force may be created by the vacuum chamber by traversing the plunger assembly to the engaged position. At the engaged position, the distal piston may engage the needle holder and the retraction force may retract the needle holder and needle into the syringe body to prevent accidental needle pricking and needle reuse.

    摘要翻译： 可伸缩的安全注射器可以具有针，针保持器，注射器主体和柱塞组件。 主体的近端部分和柱塞的活塞可以限定真空室。 柱塞组件可以包括远端活塞和近端活塞，其中设置在两个柱塞之间的中间室。 通过注射器主体的通气气路连接环境空气和中间室，当柱塞组件朝向接合位置移动并允许空气被引入中间室时，允许空气从中间室逸出。 通过将柱塞组件穿过接合位置，可以通过真空室产生回缩力。 在接合位置，远端活塞可以接合针保持器，并且缩回力可以将针保持器和针缩回到注射器主体中，以防止意外针刺和针重复使用。

    Syringe
    47.
    发明授权
    Syringe 有权
    注射器

    公开(公告)号：US07972300B2

    公开(公告)日：2011-07-05

    申请号：US11439802

    申请日：2006-05-24

    申请人： Jeffrey Smith ,  Daniel Thayer ,  Rex O. Bare

    发明人： Jeffrey Smith ,  Daniel Thayer ,  Rex O. Bare

    IPC分类号： A61M5/00 ,  A61M5/32

    CPC分类号： A61M5/3234 ,  A61M2005/3224 ,  A61M2005/3242

    摘要： A retractable needle safety syringe is provided having a braking mechanism. The braking mechanism may be disposed at a proximal portion of a syringe body of the syringe. The braking mechanism may comprise a brake member which is traversable between a braking position and a released position. At the braking position, fingers of the brake member frictionally engage an outer surface of the shaft of a plunger of the syringe. The frictional engagement counterbalances a retraction force that urges a piston of the syringe toward a retracted position. When the brake members are traversed to the released position, the fingers do not press against the outer surface of the shaft. As such, the retraction force may traverse the piston toward the retracted position and traverse a needle and needle holder into the body of the syringe.

    摘要翻译： 提供具有制动机构的伸缩针安全注射器。 制动机构可以设置在注射器的注射器主体的近端部分。 制动机构可以包括可在制动位置和释放位置之间移动的制动构件。 在制动位置，制动部件的指状物摩擦地接合注射器的柱塞的轴的外表面。 摩擦接合抵消了将注射器的活塞推向缩回位置的回缩力。 当制动构件横穿到释放位置时，手指不会压在轴的外表面上。 因此，缩回力可以朝向缩回位置移动活塞，并且将针和针保持器穿过注射器的主体。

    HUBBED DUAL CANNULA DEVICE FOR CLOSED CONTAINER SAMPLING SYSTEMS
    50.
    发明申请
    HUBBED DUAL CANNULA DEVICE FOR CLOSED CONTAINER SAMPLING SYSTEMS 审中-公开
    用于封闭式集装箱采样系统的双通道装置（HUBBED DUAL CANNULA DEVICE FOR CLOSED CONTAINER SAMPLING SYSTEMS）

    公开(公告)号：US20090305315A1

    公开(公告)日：2009-12-10

    申请号：US12480476

    申请日：2009-06-08

    申请人： Kent Raphael Gandola ,  David Elliott Kaplan ,  Rex O. Bare ,  Christopher Johann Johnson

    发明人： Kent Raphael Gandola ,  David Elliott Kaplan ,  Rex O. Bare ,  Christopher Johann Johnson

    IPC分类号： C12Q1/56 ,  C12M1/26 ,  C12Q1/02

    CPC分类号： B01L3/563 ,  A61M2039/0202 ,  B01L3/50825 ,  B01L2400/0487 ,  B01L2400/0694

    摘要： The present invention provides a hubbed dual cannula device for extracting a fluid sample from a closed container. The device comprises a housing hub, two substantially parallel needles, a venting valve and a hydrophobic membrane, and may be used effectively to extract a fluid sample from a sealed container, such as a vacuum tube, without damaging the cellular components or activating platelets in the fluid sample. Also provided are methods for using the disclosed device to extract a fluid sample from a closed container and kits for measuring platelet aggregation using such a device.

    摘要翻译： 本发明提供了一种用于从密闭容器中提取流体样品的轮毂式双插管装置。 该装置包括壳体毂，两个基本上平行的针，通气阀和疏水膜，并且可以有效地用于从诸如真空管的密封容器中提取流体样品，而不损坏细胞组分或激活血小板 流体样品。 还提供了使用所公开的装置从密封容器中提取流体样品的方法以及用于使用这种装置测量血小板聚集的试剂盒。