公开(公告)号：US07851411B2

公开(公告)日：2010-12-14

申请号：US10499522

申请日：2002-12-17

申请人： Peter Plath ,  Norbert Götz ,  Michael Rack ,  Andreas Landes ,  Cyrill Zagar ,  Matthias Witschel ,  Klaus Groβmann

发明人： Peter Plath ,  Norbert Götz ,  Michael Rack ,  Andreas Landes ,  Cyrill Zagar ,  Matthias Witschel ,  Klaus Groβmann

IPC分类号： A01N43/36 ,  A01N37/00 ,  A01N37/34 ,  C07D295/104 ,  C07D305/06 ,  C07C255/07

CPC分类号： C07D295/185 ,  A01N37/44 ,  A01N43/08 ,  A01N43/16 ,  C07C255/30 ,  C07C323/60 ,  C07C327/22 ,  C07C2601/02 ,  C07C2601/08 ,  C07C2601/14 ,  C07D305/08 ,  C07D307/18 ,  C07D307/20 ,  C07D307/22 ,  C07D309/14 ,  C07D319/06 ,  C07D331/04

摘要： α-Cyanoacrylates of the formula I, where: R1 is ORa wherein Ra is hydrogen, substituted alkyl, branched alkyl, branched alkenyl, cycloloalkyl, heterocyclyl, aryl, phenylalkyl or alkylimino; is NRbRc wherein Rb is hydrogen, alkyl which may be substituted, alkenyl, alkynyl; Rc is hydrogen, alkyl which may be substituted alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl, phenylalkyl or alkylimino; or Rb and Rc form an alkandiyl-chain which may be substituted; or is SRd wherein Rd is hydrogen, alkyl which may be substituted, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl, phenylalkyl or alkylimino; R2 is alkyl which may be substituted; is alkenyl or alkynyl; R3 is alkyl may be substituted; is alkenyl or alkynyl; R4 is hydrogen, halogen, cyano or alkyl; and their agriculturally useful salts, processes and intermediates for their preparation; and the use of these compounds or of compositions comprising these compounds for controlling undesirable plants are described.

摘要翻译： 式I的α-氰基丙烯酸酯，其中：R 1是OR a，其中R a是氢，取代的烷基，支链烷基，支链烯基，环烷基，杂环基，芳基，苯基烷基或烷基亚氨基; 是NRbRc，其中Rb是氢，可以被取代的烷基，烯基，炔基; Rc是氢，可以被取代的烯基，炔基，环烷基，杂环基，芳基，苯基烷基或烷基亚氨基的烷基; 或R b和R c形成可被取代的烷撑二链; 或者是其中Rd为氢的SRd，可以被取代的烷基，烯基，炔基，环烷基，杂环基，芳基，苯基烷基或烷基亚氨基; R2是可被取代的烷基; 是烯基或炔基; R3是烷基可以被取代; 是烯基或炔基; R4是氢，卤素，氰基或烷基; 及其农业上有用的盐，其制备方法和中间体; 并且描述了这些化合物或包含这些化合物的组合物用于防治不期望的植物的用途。

公开(公告)号：US07550633B2

公开(公告)日：2009-06-23

申请号：US11722395

申请日：2005-12-17

申请人： Marko Friedrich ,  Klaus Ebel ,  Norbert Götz

发明人： Marko Friedrich ,  Klaus Ebel ,  Norbert Götz

IPC分类号： C07C35/08

CPC分类号： C07C29/56 ,  C07B2200/07 ,  C07C2601/14 ,  C07C35/17

摘要： The present invention relates to a process for the preparation of isopulegol of formula (I): comprising the cyclization of citronellal of formula (II): in the presence of a tris(aryloxy)aluminum catalyst, wherein the cyclization is carried out in the presence of I. at least one acid and/or II. at least one compound selected from the group comprising carboxylic anhydrides, aldehydes, ketones and vinyl ethers.

摘要翻译： 本发明涉及制备式（I）的异胡风醇的方法：包括式（II）的香茅醛环化：在三（芳氧基）铝催化剂存在下，其中环化在存在下进行 至少一种酸和/或II。 至少一种选自羧酸酐，醛，酮和乙烯基醚的化合物。

公开(公告)号：US07388018B2

公开(公告)日：2008-06-17

申请号：US10570893

申请日：2004-09-10

申请人： Wassilios Grammenos ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Jordi Tormo i Blasco ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Oliver Wagner ,  Norbert Götz ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Maria Scherer ,  Reinhard Stierl

发明人： Wassilios Grammenos ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Jordi Tormo i Blasco ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Oliver Wagner ,  Norbert Götz ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Maria Scherer ,  Reinhard Stierl

IPC分类号： A61K31/541 ,  A61K31/496 ,  C07D417/02 ,  C07D403/02

CPC分类号： C04B35/632 ,  C07D213/42 ,  C07D215/12 ,  C07D401/12 ,  C07D409/12

摘要： Sulfonamides of the formula I where the substituents are as follows: R1 is hydrogen, alkyl, alkoxy, alkenyl or alkynyl; and R2, R3, R4, R5 are hydrogen, halogen, alkyl, alkoxy or halomethyl; R2 and R3 together may also form a phenyl, cyclopentyl or cyclohexyl ring, it being possible for these rings to carry two groups R2, and R3, R2, R3, are hydrogen, halogen, alkyl, alkoxy or halomethyl; in case a), if R2, R3, R4 and R5 are hydrogen: X is phenyl substituted by a group —C(R6)═NOR7, where R6 is alkyl and R7 is alkyl, benzyl, alkenyl, haloalkyl, haloalkenyl, alkynyl or haloalkynyl; and in case b), if at least one of the groups R2, R3, R4 and R5 is not hydrogen: X is phenyl, naphthyl or a five- or six-membered saturated, or partially unsaturated or aromatic heterocycle which is attached via a carbon atom and contains one to four heteroatoms from the group consisting of O, N and S, where X may be substituted according to the description; Processes for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi.

摘要翻译： 式I的磺酰胺，其中取代基如下：R 1是氢，烷基，烷氧基，烯基或炔基; R 2，R 3，R 4，R 5是氢，卤素，烷基，烷氧基或卤代甲基 ; R 2和R 3一起也可以形成苯基，环戊基或环己基环，这些环可以携带两个基团R 2， R 3，R 2，R 3，R 3，R 3，R 3，R 3，R 3，R 3，R 3，R 3， 在a）情况下，如果R 2，R 3，R 4和R 5是氢：X是 由基团-C（R 6） - NOR 7取代的苯基，其中R 6为烷基，R 7为H 烷基，苄基，烯基，卤代烷基，卤代烯基，炔基或卤代炔基; 并且在情况b）中，如果R 2，R 3，R 4和R 5中的至少一个， SUP>不是氢：X是苯基，萘基或五或六元饱和或部分不饱和或芳族杂环，其通过碳原子连接并含有一至四个由O，N和S组成的组的杂原子 ，其中X可以根据描述被替代; 制备这些化合物的方法，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。

公开(公告)号：US20060264446A1

公开(公告)日：2006-11-23

申请号：US10570854

申请日：2004-09-10

申请人： Ernst Baumann ,  Thomas Grote ,  Frank Schieweck ,  Wolfgang Deyn ,  Norbert Götz ,  Michael Hofmann ,  Markus Kordes ,  Michael Puhl ,  Michael Rack ,  Thomas Schmidt ,  Toni Bucci ,  Henry Cotter ,  Deborah Culbertson ,  Hassan Oloumi-Sadeghi

发明人： Ernst Baumann ,  Thomas Grote ,  Frank Schieweck ,  Wolfgang Deyn ,  Norbert Götz ,  Michael Hofmann ,  Markus Kordes ,  Michael Puhl ,  Michael Rack ,  Thomas Schmidt ,  Toni Bucci ,  Henry Cotter ,  Deborah Culbertson ,  Hassan Oloumi-Sadeghi

IPC分类号： A01N43/90

CPC分类号： C07D487/04 ,  A01N43/90

摘要： The present invention relates to a method of combating animal pests which comprises contacting the animal pests, their habit, breeding ground, food supply, plant, seed, soil, area, material or environment in which the animal pests are growing or may grow, or the materials, plants, seeds, soils, surfaces or spaces to be protected from animal attack or infestation with a pesticidally effective amount of at least one 6-halogeno[1,2,4]triazolo[1,5-a]-pyrimidine of the general formula (I), wherein X, R1, R2, R3 and R4 are as defined in claim 1 and/or the agriculturally useful salts thereof.

摘要翻译： 本发明涉及一种对抗动物害虫的方法，其包括使动物害虫，其习惯，繁殖地，食物供应，植物，种子，土壤，面积，材料或动物害虫生长或可能生长的环境接触;或 要防止动物攻击或侵染的材料，植物，种子，土壤，表面或空间，用杀虫有效量的至少一种6-卤代[1,2,4]三唑并[1,5-a] - 嘧啶 通式（I）其中X，R 1，R 2，R 3和R 4均为 如权利要求1所定义，和/或其农业上有用的盐。

公开(公告)号：US06888003B2

公开(公告)日：2005-05-03

申请号：US10221206

申请日：2001-03-15

申请人： Cyrill Zagar ,  Robert Reinhard ,  Michael Puhl ,  Thorsten Volk ,  Norbert Götz ,  Gerhard Hamprecht ,  Olaf Menke ,  Ingo Sagasser

发明人： Cyrill Zagar ,  Robert Reinhard ,  Michael Puhl ,  Thorsten Volk ,  Norbert Götz ,  Gerhard Hamprecht ,  Olaf Menke ,  Ingo Sagasser

IPC分类号： C07D231/12 ,  A01N43/56 ,  A01N43/76 ,  C07B61/00 ,  C07D231/16 ,  C07D231/18 ,  C07D413/04 ,  C07D413/14 ,  C07D498/00

CPC分类号： C07D413/04 ,  A01N43/56

摘要： A process for preparing 7-(pyrazol-3-yl)benzoxazoles of the formula I in which the variables R1-R6 are as defined in claim 1, which process is characterized in that a 2-halo-3-(pyrazol-3-yl)anilide of the formula II, in which X is bromine or iodine is reacted with a base in the presence of a transition metal compound of subgroup VIIa, VIIIa or Ib of the Periodic Table of the Elements, is disclosed.

摘要翻译： 制备其中变量R 1〜6的定义的式I的7-（吡唑-3-基）苯并恶唑的方法如权利要求1所定义，该方法 其特征在于式Ⅱ的2-卤代-3-（吡唑-3-基）酰苯胺，其中X是溴或碘，在Ⅶa族，Ⅷa族或Ⅷa族过渡金属化合物存在下与碱反应 公开了元素周期表的Ib。

公开(公告)号：US06831039B1

公开(公告)日：2004-12-14

申请号：US09857067

申请日：2001-05-21

申请人： Ulf Neidlein ,  Norbert Götz ,  Ernst Baumann ,  Wolfgang von Deyn ,  Steffen Kudis ,  Klaus Langemann ,  Guido Mayer ,  Ulf Misslitz ,  Matthias Witschel ,  Martina Otten ,  Karl-Otto Westphalen ,  Helmut Walter

发明人： Ulf Neidlein ,  Norbert Götz ,  Ernst Baumann ,  Wolfgang von Deyn ,  Steffen Kudis ,  Klaus Langemann ,  Guido Mayer ,  Ulf Misslitz ,  Matthias Witschel ,  Martina Otten ,  Karl-Otto Westphalen ,  Helmut Walter

IPC分类号： A01N4356

CPC分类号： C07D413/10 ,  C07D231/20

摘要： The invention relates to 3-(heterocyclyl)-substituted benzoylpyrazois of formula (I), wherein the variables have the following meanings: X is O, NH or N-alkyl; R1 is alkyl; R2, R3, R4, R5 are hydrogen, alkyl or alkyl halide; R6 is halogen, nitro, alkyl halide, alkoxy, halogenalkoxy, alkylthio, halogenalkylthio, alkylsulfonyl or halogenalkylsulfonyl; R7 is hydroxy, alkoxy, alkenyloxy, alkylsulfonyloxy, alkylcarboyloxy, alkylthiocarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, and the phenyl radical can be substituted; R8, R9 are alkyl; R10 is hydrogen or alkyl; and R11 is hydrogen or alkyl; and to their agriculturally useable salts. The invention also relates to intermediate products and methods for producing the inventive compounds and to the use of these compounds or products containing them for combating undesirable plants.

摘要翻译： 本发明涉及式（I）的3-（杂环基）取代的苯甲酰基吡啶，其中变量具有以下含义：X是O，NH或N-烷基; R 1是烷基; R 2，R 3，R 4，R 5是氢，烷基或烷基卤; R 6是卤素，硝基，烷基卤，烷氧基，卤代烷氧基，烷硫基，卤代烷硫基，烷基磺酰基或卤代烷基磺酰基; R 7是羟基，烷氧基，烯氧基，烷基磺酰氧基，烷基羰氧基，烷硫基羰基氧基，苯基磺酰氧基或苯基羰基氧基，苯基可以被取代; R 8，R 9是烷基; R 10是氢或烷基; 和R 11是氢或烷基; 以及其农业上可用的盐类。 本发明还涉及用于生产本发明化合物的中间产物和方法以及含有它们的这些化合物或产品用于对抗不期望的植物的用途。

公开(公告)号：US06696607B2

公开(公告)日：2004-02-24

申请号：US10297287

申请日：2002-12-04

申请人： Wassilios Grammenos ,  Hubert Sauter ,  Oliver Cullmann ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Norbert Götz ,  Thorsten Volk ,  Gisela Lorenz ,  Eberhard Ammermann ,  Reinhard Stierl ,  Siegfried Strathmann

发明人： Wassilios Grammenos ,  Hubert Sauter ,  Oliver Cullmann ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Norbert Götz ,  Thorsten Volk ,  Gisela Lorenz ,  Eberhard Ammermann ,  Reinhard Stierl ,  Siegfried Strathmann

IPC分类号： C07C23309

CPC分类号： A01N37/36 ,  A01N37/18 ,  A01N37/38 ,  C07C231/02 ,  C07C233/22

摘要： Use of phenethylacrylamides of the formula I: in which the substituents have the following meanings: X is halogen, alkyl, haloalkyl, alkoxy, haloalkoxy and —O—C(Ra,Rb)—C≡C—R6; Ra,Rb and Rc have the meanings given in the description; m,n independently of one another are 1 to 4, it being possible for the radicals X or Y to be different if m or n is greater than 1; Y is halogen, nitro, cyano, alkyl, CF3, alkoxy and phenyl; R1,R2 independently of one another are hydrogen, halogen, alkyl, alkoxy, haloalkoxy and CF3; R3,R4,R5,R6 independently of one another are hydrogen, halogen, alkyl, alkoxy, or R3 and R4 together form a cyclopropyl ring, it being possible for the C—R5— and C—R6 bonds can be in the E- or Z-position relative to each other; for controlling phytopathogenic fungal pests, novel phenethylacrylamides, their preparation, and compositions comprising them.

摘要翻译： 使用式I的苯乙基丙烯酰胺：其中取代基具有以下含义：X是卤素，烷基，卤代烷基，烷氧基，卤代烷氧基和-OC（R a，R b）-C = CR 6; R a，R b和R c具有说明书中给出的含义; m，n彼此独立地为1至4，如果m或n可以使基团X或Y不同 大于1; Y是卤素，硝基，氰基，烷基，CF 3，烷氧基和苯基; R 1，R 2彼此独立地是氢，卤素，烷基，烷氧基，卤代烷氧基和CF 3; R 3 R 4，R 5，R 6彼此独立地是氢，卤素，烷基，烷氧基或R 3和R 4一起形成环丙基环，其中CR <5> - 和CR 6键可以相对于彼此位于E-或Z-位;用于控制植物病原性真菌害虫，新型苯乙基丙烯酰胺，它们的制备和包含它们的组合物。

公开(公告)号：US06670482B2

公开(公告)日：2003-12-30

申请号：US10223019

申请日：2002-08-19

申请人： Wolfgang von Deyn ,  Joachim Gebhardt ,  Michael Rack ,  Rene Lochtman ,  Norbert Götz ,  Michael Keil ,  Matthias Witschel ,  Helmut Hagen ,  Ulf Misslitz ,  Ernst Baumann

发明人： Wolfgang von Deyn ,  Joachim Gebhardt ,  Michael Rack ,  Rene Lochtman ,  Norbert Götz ,  Michael Keil ,  Matthias Witschel ,  Helmut Hagen ,  Ulf Misslitz ,  Ernst Baumann

IPC分类号： C07D26104

CPC分类号： C07D413/10 ,  C07C251/48 ,  C07C319/14 ,  C07D261/04 ,  C07D261/08 ,  C07C323/09

摘要： The present invention describes a process for preparing isoxazoles of the formula I where: R1 is hydrogen, C1-C6-alkyl, R2 is hydrogen, C1-C6-alkyl, R3, R4, R5 are each hydrogen, C1-C6-alkyl or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are each as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Furthermore, the invention describes novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates.

摘要翻译： 本发明描述了制备式I的异恶唑的方法，其中R 1是氢，C 1 -C 6烷基，R 2是氢，C 1 -C 6烷基，R 3，R 4， R 5各自为氢，C 1 -C 6 - 烷基或R 4和R 5一起形成键，R 6为杂环，n为0,1或2;其包括制备中间体 其中R 1，R 3，R 4和R 5各自如上所定义，然后进行卤化，硫甲基化，氧化和酰化，得到式I化合物。此外，本发明 描述了制备式I化合物的新型中间体和制备中间体的新方法。

公开(公告)号：US06548677B1

公开(公告)日：2003-04-15

申请号：US09856037

申请日：2001-05-17

申请人： Michael Rack ,  Norbert Götz ,  Helmut Hagen ,  Wolfgang von Deyn ,  Ernst Baumann ,  Rene Lochtman ,  Joachim Gebhardt

发明人： Michael Rack ,  Norbert Götz ,  Helmut Hagen ,  Wolfgang von Deyn ,  Ernst Baumann ,  Rene Lochtman ,  Joachim Gebhardt

IPC分类号： C07D26118

CPC分类号： C07D261/04

摘要： A novel process for preparing the compounds of the formula I where: n is 0, 1 or 2; R1, R2 are C1-C6-alkyl; R3, R4, R5 are hydrogen or C1-C6-alkyl, or R4 and R5 together form a bond; R6 is Cl, Br, which comprises a synthesis sequence starting from 1,2-dialkylbenzenes of the formula II with subsequent halogenation to give 3,6-dihalo-1,2-dialkylbenzenes, haloalkylation to give benzyl bromides, oxidation to give benzaldehydes, oximation, reaction with alkenes to give isoxazoles, conversion into thioethers and, if appropriate, oxidation to give sulfenyl or sulfonyl derivatives of the formula I.

摘要翻译： 一种制备式I化合物的新方法，其中n为0,1或2; R 1，R 2为C 1 -C 6 - 烷基; R 3，R 4，R 5为氢或C 1 -C 6烷基，或者R 4和R 5一起形成 R 6是Cl，Br，其包含从式II的1,2-二烷基苯开始的合成序列，随后卤化以得到3,6-二卤代-1,2-二烷基苯，卤代烷基化得到苄基溴，氧化得到 苯甲醛，肟化，与烯烃的反应得到异恶唑，转化成硫醚，如果合适，氧化得到式I的磺酰基或磺酰基衍生物。

公开(公告)号：US08124810B2

公开(公告)日：2012-02-28

申请号：US12651946

申请日：2010-01-04

申请人： Joachim Rheinheimer ,  Wolfgang von Deyn ,  Joachim Gebhardt ,  Michael Rack ,  Rene Lochtman ,  Norbert Götz ,  Michael Keil ,  Matthias Witschel ,  Helmut Hagen ,  Ulf Miβlitz ,  Ernst Baumann

发明人： Joachim Rheinheimer ,  Wolfgang von Deyn ,  Joachim Gebhardt ,  Michael Rack ,  Rene Lochtman ,  Norbert Götz ,  Michael Keil ,  Matthias Witschel ,  Helmut Hagen ,  Ulf Miβlitz ,  Ernst Baumann

IPC分类号： C07C319/14

CPC分类号： C07C249/06 ,  C07C201/10 ,  C07C201/12 ,  C07C205/44 ,  C07C209/62 ,  C07C251/48 ,  C07C253/00 ,  C07C255/50 ,  C07C315/04 ,  C07C319/14 ,  C07D261/04 ,  C07D413/10 ,  C07C323/09 ,  C07C317/24 ,  C07C317/32 ,  C07C205/06 ,  C07C211/52

摘要： A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.

摘要翻译： 描述了制备式I的异恶唑的方法，其中取代基如下所定义：R 1是氢，C 1 -C 6烷基，R 2是C 1 -C 6烷基，R 3，R 4，R 5是氢，C 1 -C 6 - 烷基 ，或R4和R5一起形成键，R6是杂环，n是0,1或2; 其包括制备式VI的中间体，其中R 1，R 3，R 4和R 5如上定义，然后进行卤化，硫甲基化，氧化和酰化，得到式I化合物。还有用于制备式I化合物的中间体 并描述了制备中间体的新方法。