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88 条记录 (耗时 0.038 秒)

    Therapeutic device and method for treating diseases of cardiac muscle
    42.
    发明授权
    Therapeutic device and method for treating diseases of cardiac muscle 有权

    公开(公告)号：US07039467B2

    公开(公告)日：2006-05-02

    申请号：US10388073

    申请日：2003-03-13

    申请人： John A. Hauck

    发明人： John A. Hauck

    IPC分类号： A61N1/362

    CPC分类号： A61N1/08 ,  A61N1/326 ,  A61N1/3627

    摘要： An apparatus and method for conferring a therapeutic current to the heart is provided. The apparatus includes a first electrode, a second electrode, a current generator and a controller. The apparatus may further include a sensor. The sensor is generally configured to measure field strength between the first and second electrode. The sensor may also monitor the cardiac cycle. The method includes applying an electric stimulus to the heart and sensing the electric field generated by the electric stimulus to prevent the level of current from inducing unwanted depolarization.

    Electrode charge-neutral sensing of evoked ECG
    43.
    发明授权
    Electrode charge-neutral sensing of evoked ECG 失效
    电极电荷中性感应诱发心电图

    公开(公告)号：US5330512A

    公开(公告)日：1994-07-19

    申请号：US997442

    申请日：1992-12-28

    申请人： John A. Hauck ,  Julio C. Spinelli

    发明人： John A. Hauck ,  Julio C. Spinelli

    IPC分类号： A61N1/365 ,  A61N1/37 ,  A61N1/00

    CPC分类号： A61N1/3706

    摘要： A cardiac pacemaker signal processing circuit adapted to obtain an evoked ECG signal. The circuit senses the electrical signals of the ring and tip electrodes in the unipolar mode from the bipolar lead after the electrical pacing stimulus has been applied to contract the ventricle of the heart. The residual oppositely polarized potentials at the ring and tip electrode, as well as the sensed evoked ECG signals, are added together to cancel out the opposing residual potentials, but to add the common polarized ECG signal. Thus, a high quality evoked ECG signal is obtained, free of the residual potentials, and subsequently utilized by R-wave detection circuits for sensing the QRS complex. The circuit includes compensating signal processing circuits to provide time domain signal processing weighting functions to match exponential time delay of the tip and ring electrodes, and includes amplitude adjusting compensation as well. Thus, the absolute amplitudes of the opposite polarized residual potentials will be adjusted to be equal, are summed, and canceled or nulled at the appropriate time in the time domain. Both biphasic and tripbasic pace pulse techniques are not required, the pace pulse amplitude can be reduced to extend the battery life of the pacemaker. Further, the post pace re-charging cycle is only interrupted and undertaken-passively to, again, reduce current drain on the battery. Classic R-wave detection circuits are adaptable to the signal processing circuit of the present invention.

    摘要翻译： 一种心脏起搏器信号处理电路，其适于获得诱发的ECG信号。 在施加电起搏刺激以收缩心脏心室之后，该电路感测来自双极引线的单极模式的环和尖端电极的电信号。 在环和尖端电极处的残留的相反极化电位以及感测到的诱发ECG信号被加在一起以抵消相对的残留电位，而是添加公共极化ECG信号。 因此，获得高质量的诱发ECG信号，没有剩余电位，并随后被R波检测电路用于感测QRS复合物。 电路包括补偿信号处理电路，以提供时域信号处理加权函数，以匹配尖端和环形电极的指数时间延迟，并且还包括幅度调整补偿。 因此，相反的极化残余电位的绝对幅度将被调整为相等，被相加，并在时域中的适当时间被消除或置零。 不需要双相和三相起搏脉冲技术，可以减小起搏脉冲幅度以延长起搏器的电池寿命。 此外，后续重新充电周期仅被中断，被动地被动地减少电池的电流消耗。 经典R波检测电路适用于本发明的信号处理电路。

    Navigational reference dislodgement detection method and system
    45.
    发明授权
    Navigational reference dislodgement detection method and system 有权
    导航参考检测方法及系统

    公开(公告)号：US09220439B2

    公开(公告)日：2015-12-29

    申请号：US11647277

    申请日：2006-12-29

    申请人： John A. Hauck

    发明人： John A. Hauck

    IPC分类号： A61B5/06 ,  A61B19/00

    CPC分类号： A61B5/06 ,  A61B5/042 ,  A61B5/063 ,  A61B5/7221 ,  A61B34/20 ,  A61B2034/2051 ,  A61B2034/2053 ,  A61B2034/2072

    摘要： A method of tracking a position of a catheter within a patient includes securing a navigational reference at a reference location within the patient, defining the reference location as the origin of a coordinate system, determining a location of an electrode moving within the patient relative to that coordinate system, monitoring for a dislodgement of the navigational reference from the initial reference location, for example by measuring the navigational reference relative to a far field reference outside the patient's body, and generating a signal indicating that the navigational reference has dislodged from the reference location. Upon dislodgement, a user may be provided with guidance to help reposition and secure the navigational reference to the initial reference location, or the navigational reference may be automatically repositioned and secured to the initial reference location. Alternatively, a reference adjustment may be calculated to compensate for the changed reference point/origin.

    摘要翻译： 跟踪患者中导管位置的方法包括：将参考位置固定在患者内的参考位置，将参考位置定义为坐标系的原点，确定在患者体内相对于坐标系移动的电极的位置 协调系统，例如通过测量与患者身体外部的远场参考相关的导航参考，以及生成指示导航参考已经从参考位置移除的信号来监测导航参考从初始参考位置的移除 。 在移动时，可以向用户提供指导以帮助重新定位并确保对初始参考位置的导航参考，或者导航参考可以被自动重新定位并且被固定到初始参考位置。 或者，可以计算参考调整以补偿改变的参考点/原点。

    Dynamic adaptive respiration compensation with automatic gain control
    46.
    发明授权
    Dynamic adaptive respiration compensation with automatic gain control 有权
    动态自适应呼吸补偿与自动增益控制

    公开(公告)号：US09113807B2

    公开(公告)日：2015-08-25

    申请号：US12980515

    申请日：2010-12-29

    申请人： Lev A. Koyrakh ,  Eric J. Voth ,  John A. Hauck ,  Jeffrey A. Schweitzer

    发明人： Lev A. Koyrakh ,  Eric J. Voth ,  John A. Hauck ,  Jeffrey A. Schweitzer

    IPC分类号： A61B5/053 ,  A61B5/00 ,  A61B5/06 ,  H04L25/03 ,  H04L25/02

    CPC分类号： A61B5/7207 ,  A61B5/0044 ,  A61B5/053 ,  A61B5/0536 ,  A61B5/0538 ,  A61B5/06 ,  A61B5/061 ,  A61B5/063 ,  A61B5/6801 ,  A61B5/7203 ,  A61B5/721 ,  A61B5/7267 ,  A61B5/742 ,  H04L25/0278 ,  H04L25/03019

    摘要： A system for determining a location of an electrode of a medical device (e.g., a catheter) in a body of a patient includes a localization block for producing an uncompensated electrode location, a motion compensation block for producing a compensation signal (i.e., for respiration, cardiac, etc.), and a mechanism for subtracting the compensation signal from the uncompensated electrode location. The result is a corrected electrode location substantially free of respiration and cardiac artifacts. The motion compensation block includes a dynamic adaptation feature which accounts for changes in a patient's respiration patterns as well as intentional movements of the medical device to different locations within the patient's body. The system further includes an automatic compensation gain control which suppresses compensation when certain conditions, such as noise or sudden patch impedance changes, are detected.

    摘要翻译： 用于确定患者体内的医疗装置（例如，导管）的电极的位置的系统包括用于产生未补偿的电极位置的定位块，用于产生补偿信号的运动补偿块（即，用于呼吸 ，心脏等），以及用于从未补偿的电极位置减去补偿信号的机构。 结果是基本上没有呼吸和心脏伪影的校正电极位置。 运动补偿块包括动态适应特征，其考虑了患者呼吸模式的变化以及医疗装置对患者体内不同位置的有意移动。 该系统还包括自动补偿增益控制，当检测到某些条件（例如噪声或突发阻抗变化）时，该自动补偿增益控制抑制补偿。

    Robotically controlled catheter and method of its calibration
    47.
    发明申请
    Robotically controlled catheter and method of its calibration 有权
    机器人控制的导管及其校准方法

    公开(公告)号：US20140081290A1

    公开(公告)日：2014-03-20

    申请号：US13778893

    申请日：2013-02-27

    申请人： John A. Hauck

    发明人： John A. Hauck

    IPC分类号： A61B19/00 ,  A61M25/01

    CPC分类号： A61B19/20 ,  A61B1/0052 ,  A61B5/042 ,  A61B5/7257 ,  A61B34/20 ,  A61B34/30 ,  A61B34/70 ,  A61B34/71 ,  A61B90/10 ,  A61B2017/003 ,  A61B2017/00699 ,  A61B2017/00703 ,  A61B2017/00725 ,  A61B2017/22075 ,  A61B2017/3409 ,  A61B2034/2051 ,  A61B2034/2053 ,  A61B2034/301 ,  A61B2034/742 ,  A61B2560/0223 ,  A61M25/0105 ,  A61M25/0133

    摘要： A method of calibrating a robotic device, such as a cardiac catheter, includes oscillating the device on an actuation axis by applying an oscillation vector at an oscillation frequency. While oscillating, a location of the device is periodically measured to generate a plurality of location data points, which may express the location of the device relative to a plurality of measurement axes. The location data points are then processed using a signal processing algorithm, such as a Fourier transform algorithm, to derive a transfer function relating a position of the device to a movement vector for the actuation axis. The transfer function may be resolved into and expressed as a calibration vector for the actuation axis, which may include one or more components, including zero components, directed along each of the measurement axes. The process may be repeated for any actuation axes on which calibration is desired.

    摘要翻译： 校准诸如心脏导管的机器人装置的方法包括通过施加振荡频率的振荡矢量来振荡装置在致动轴上。 在振荡的同时，周期性地测量设备的位置以产生多个位置数据点，其可以表示设备相对于多个测量轴的位置。 然后使用诸如傅立叶变换算法的信号处理算法来处理位置数据点，以导出将装置的位置与致动轴的运动矢量相关联的传递函数。 传递函数可以被解析为并且表示为用于致动轴的校准矢量，其可以包括沿着每个测量轴指向的一个或多个零件，包括零分量。 对于期望校准的任何致动轴，可以重复该过程。

    Cardiac tissue elasticity sensing
    48.
    发明授权
    Cardiac tissue elasticity sensing 有权
    心脏组织弹性检测

    公开(公告)号：US08644950B2

    公开(公告)日：2014-02-04

    申请号：US13413235

    申请日：2012-03-06

    申请人： John A. Hauck

    发明人： John A. Hauck

    IPC分类号： A61N1/08 ,  A61B5/02

    CPC分类号： A61B18/1233 ,  A61B5/0053 ,  A61B5/02007 ,  A61B5/103 ,  A61B5/441 ,  A61B5/4519 ,  A61B5/6852 ,  A61B5/6885 ,  A61B18/14 ,  A61B18/1492 ,  A61B2034/2051 ,  A61B2090/062 ,  A61B2090/064

    摘要： A system and method are provided for assessing the compliance of internal patient tissue for purposes of catheter guidance and/or ablation procedures. Specifically, the system/method provides for probing internal patient tissue in order to obtain force and/or tissue displacement measurements. These measurements are utilized to generate an indication of tissue elasticity. In one exemplary embodiment, the indication of elasticity is correlated with an image of the internal tissue area and an output of this image including elasticity indications is displayed for a user.

    摘要翻译： 提供了一种用于评估用于导管引导和/或消融过程的内部患者组织的依从性的系统和方法。 具体地，系统/方法提供了探测内部患者组织以获得力和/或组织位移测量。 这些测量用于产生组织弹性的指示。 在一个示例性实施例中，弹性指示与内部组织区域的图像相关，并且包括弹性指示的该图像的输出被显示给用户。

    Cardiac navigation system including electrode array for use therewith
    49.
    发明授权
    Cardiac navigation system including electrode array for use therewith 有权
    心脏导航系统包括与其一起使用的电极阵列

    公开(公告)号：US08489171B2

    公开(公告)日：2013-07-16

    申请号：US13097783

    申请日：2011-04-29

    申请人： John A. Hauck ,  James C. Baker

    发明人： John A. Hauck ,  James C. Baker

    IPC分类号： A61B5/04

    CPC分类号： A61B5/042 ,  A61B5/1076

    摘要： A cardiac navigation system including a mapping catheter, a control system coupled to the mapping catheter, an electrode array, and means for driving an electrical current across the electrode array. The mapping catheter includes means for sensing an electrical field. The control system includes means for receiving sensed signals from the mapping catheter. The cardiac navigation system includes at least one electrode array including means for providing an electrical field across three axes. The three axes are approximately orthogonal with respect to one another. The means for driving an electrical current across the three axes includes means for providing a plurality of individual current sources to the electrode array. As such, the cardiac navigation system presented provides a more uniform sheet of current across an area of interest, the mapping catheter senses the electrical field across the area of interest, and the control system determines a three-dimensional location of the mapping catheter based on the sensed electrical field.

    摘要翻译： 包括映射导管，耦合到映射导管的控制系统，电极阵列以及用于驱动穿过电极阵列的电流的装置的心导航系统。 映射导管包括用于感测电场的装置。 控制系统包括用于从映射导管接收感测信号的装置。 心脏导航系统包括至少一个电极阵列，其包括用于在三个轴上提供电场的装置。 三个轴彼此大致正交。 用于驱动横跨三个轴的电流的装置包括用于向电极阵列提供多个单独的电流源的装置。 因此，所呈现的心脏导航系统在感兴趣区域提供更均匀的电流片，映射导管感测感兴趣区域上的电场，并且控制系统基于以下方式确定映射导管的三维位置： 感应电场。