Crystalline pharmaceutically acceptable salts of an oxazolidinone derivative
    41.
    发明授权
    Crystalline pharmaceutically acceptable salts of an oxazolidinone derivative 失效
    恶唑烷酮衍生物的结晶药学上可接受的盐

    公开(公告)号:US06329393B1

    公开(公告)日:2001-12-11

    申请号:US09460267

    申请日:1999-12-13

    IPC分类号: A61K31445

    CPC分类号: C07D413/12

    摘要: A crystalline pharmaceutically acceptable benzenesulfonate salt of Compound A of formula: and solvates thereof are disclosed. Compound A and its benzenesulfonate salts are alpha 1a adrenergic receptor antagonists useful in the treatment of benign prostatic hyperplasia. Pharmaceutical compositions employing the crystalline salts, and processes for making and using the crystalline salts are also disclosed.

    摘要翻译: 公开了具有下式的化合物A的结晶药学上可接受的苯磺酸盐及其溶剂合物。 化合物A及其苯磺酸盐是可用于治疗良性前列腺增生的α1-肾上腺素能受体拮抗剂。 还公开了使用结晶盐的药物组合物,以及制备和使用结晶盐的方法。

    Latent user models for personalized ranking
    46.
    发明授权
    Latent user models for personalized ranking 有权
    潜在用户模型,用于个性化排名

    公开(公告)号:US09477757B1

    公开(公告)日:2016-10-25

    申请号:US13517767

    申请日:2012-06-14

    IPC分类号: G06F17/30

    CPC分类号: G06F17/30864

    摘要: A method includes generating a ranking model and a baseline mixing weight for each latent user category from a plurality of latent user categories based on a community preference dataset and one or more latent variables that relate the users from the community of users to the latent user categories. The method also includes generating a personalized mixing weight for each latent user category for a specified user based on an individual preference dataset, the ranking models for the latent user category, and one or more latent variables that relate the specified user to the latent user categories. The method also includes adjusting the personalized mixing weight for each latent user category for the specified user based on the baseline mixing weights, and generating ranking output for at least some objects from the plurality of objects using the personalized mixing weights and the ranking models.

    摘要翻译: 一种方法包括基于社区偏好数据集以及将来自用户社区的用户与潜在用户类别相关联的一个或多个潜在变量来生成来自多个潜在用户类别的每个潜在用户类别的排名模型和基准混合权重 。 该方法还包括基于个人偏好数据集,潜在用户类别的排名模型以及将指定用户与潜在用户类别相关联的一个或多个潜在变量为特定用户的每个潜在用户类别生成个性化混合权重 。 该方法还包括基于基线混合权重调整针对指定用户的每个潜在用户类别的个性化混合权重,以及使用个性化混合权重和排名模型从多个对象中生成至少一些对象的排名输出。

    Method for preparing polyoxymethylene dimethyl ethers by acetalation reaction of formaldehyde with methanol
    48.
    发明授权
    Method for preparing polyoxymethylene dimethyl ethers by acetalation reaction of formaldehyde with methanol 有权
    通过甲醛与甲醇的缩醛化反应制备聚甲醛二甲醚的方法

    公开(公告)号:US08987521B2

    公开(公告)日:2015-03-24

    申请号:US13164677

    申请日:2011-06-20

    IPC分类号: C07C41/14 C07C41/56 C07C41/58

    摘要: It is disclosed a method for preparing polyoxymethylene dimethyl ethers by continuous polymerization and acetalation reactions. The method may include two steps: performing a polymerization reaction of an aqueous formaldehyde solution under catalysis of an ionic liquid IL I to obtain a mixed aqueous solution of trioxymethylene and formaldehyde; and an acetalation reaction of the mixed aqueous solution of trioxymethylene and formaldehyde with methanol is performed under catalysis of an ionic liquid IL II to prepare polyoxymethylene dimethyl ethers. The method may use an aqueous formaldehyde solution as a starting material to prepare polyoxymethylene dimethyl ethers by continuous polymerization and acetalation reactions, achieving a high use ratio of formaldehyde. A film evaporator is used in the invention, realizing a rapid separation and recycling of the light components, with a high separation efficiency. The separation of the catalyst is simple, thereby realizing recycling of the catalyst.

    摘要翻译: 公开了通过连续聚合和缩醛化反应制备聚甲醛二甲醚的方法。 该方法可以包括以下两个步骤:在离子液体IL I的催化下进行甲醛水溶液的聚合反应,得到三甲基甲醛和甲醛的混合水溶液; 并且在离子液体IL II的催化下进行三甲醛和甲醛与甲醇的混合水溶液的缩醛化反应,以制备聚甲醛二甲醚。 该方法可以使用甲醛水溶液作为起始原料,通过连续聚合和缩醛化反应制备聚甲醛二甲醚,实现甲醛的高使用比例。 在本发明中使用薄膜蒸发器,以高分离效率实现轻组分的快速分离和再循环。 催化剂的分离是简单的,从而实现催化剂的再循环。

    Non-Intrusive Pressure Sensor System
    49.
    发明申请
    Non-Intrusive Pressure Sensor System 审中-公开
    非侵入式压力传感器系统

    公开(公告)号:US20150055679A1

    公开(公告)日:2015-02-26

    申请号:US14321605

    申请日:2014-07-01

    申请人: Zhen Li

    发明人: Zhen Li

    IPC分类号: G01K13/02 G01L7/02

    摘要: A conduit pressure sensor system and a process for non-intrusively determining the pressure within a conduit. In one example, the sensor system has a base section having an external surface and an internal region in fluid connection with the conduit. A strain sensor and a temperature sensor are positioned adjacent to the external surface of the base section.

    摘要翻译: 管道压力传感器系统和用于非侵入性地确定管道内的压力的过程。 在一个示例中,传感器系统具有基部,其具有外部表面和与导管流体连接的内部区域。 应变传感器和温度传感器邻近基部的外表面定位。

    Circuit for a front-end tunable filter of a communication and broadcast receiver and a tuning method thereof
    50.
    发明授权
    Circuit for a front-end tunable filter of a communication and broadcast receiver and a tuning method thereof 有权
    通信和广播接收机的前端可调谐滤波器的电路及其调谐方法

    公开(公告)号:US08862089B2

    公开(公告)日:2014-10-14

    申请号:US13655264

    申请日:2012-10-18

    摘要: A circuit for a front-end tunable filter of a communication and broadcast receiver and a tuning method thereof are described herein. In one aspect, the circuit of the tunable filter may be independent of the signal reception link of the receiver. The pre-filter (104) includes a variable capacitance (146) which is adjusted by a tuning signal (160). A negative resistance element (144) and the pre-filter (104) may form an oscillator. The negative resistance element (144) is controlled by an amplitude control signal (162) outputted from an oscillation amplitude control circuit (142). The oscillation amplitude control circuit (142) stabilizes the amplitude of a radio frequency signal (130) in a preset range. An oscillation frequency control circuit (140) stabilizes the frequency of the signal (130) in a preset frequency range by a tuning signal (160). The tuning is completed until both of the amplitude and the frequency of the oscillation signal meet the preset ranges.

    摘要翻译: 本文描述了用于通信和广播接收机的前端可调滤波器的电路及其调谐方法。 在一个方面,可调滤波器的电路可以独立于接收机的信号接收链路。 预滤波器(104)包括由调谐信号(160)调节的可变电容(146)。 负电阻元件(144)和预滤波器(104)可以形成振荡器。 负电阻元件(144)由从振荡幅度控制电路(142)输出的振幅控制信号(162)控制。 振荡幅度控制电路(142)将射频信号(130)的振幅稳定在预设范围内。 振荡频率控制电路(140)通过调谐信号(160)使信号(130)的频率在预设频率范围内稳定。 调谐完成,直到振荡信号的幅度和频率都达到预设范围。