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41.发明授权公开(公告)号：US11072774B2
公开(公告)日：2021-07-27
申请号：US17175612
申请日：2021-02-13
Applicant: Inscripta, Inc.
Inventor： Phillip Belgrader , Don Masquelier , Andrew Garst , Richard Fox
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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42.发明申请公开(公告)号：US20210155894A1
公开(公告)日：2021-05-27
申请号：US17159137
申请日：2021-01-26
Applicant: Inscripta, Inc.
Inventor： Richard Fox , Daniel Held , Eric Abbate , Michael Clay , Katherine Krouse , Nandini Krishnamurthy , Krishna Yerramsetty
IPC: C12N1/20 , C07K14/245
Abstract: The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
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43.发明申请公开(公告)号：US20200230556A1
公开(公告)日：2020-07-23
申请号：US16844330
申请日：2020-04-09
Applicant: Inscripta, Inc.
Inventor： Phillip Belgrader , Don Masquelier , Matthew Estes , Bruce Chabansky , Andrew Garst , Richard Fox , Jorge Bernate
IPC: B01D63/08
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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44.发明授权公开(公告)号：US10647958B2
公开(公告)日：2020-05-12
申请号：US16693630
申请日：2019-11-25
Applicant: Inscripta, Inc.
Inventor： Phillip Belgrader , Don Masquelier , Bruce Chabansky , Jorge Bernate , Andrew Garst , Richard Fox
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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45.发明申请公开(公告)号：US20200056143A1
公开(公告)日：2020-02-20
申请号：US16454865
申请日：2019-06-27
Applicant: Inscripta, Inc.
Inventor： Andrew Garst , Richard Fox , Phillip Belgrader , Don Masquelier
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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Patent Agency Ranking
46.发明授权公开(公告)号：US10550363B1
公开(公告)日：2020-02-04
申请号：US16454865
申请日：2019-06-27
Applicant: Inscripta, Inc.
Inventor： Andrew Garst , Richard Fox , Phillip Belgrader , Don Masquelier
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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47.发明授权公开(公告)号：US10532324B1
公开(公告)日：2020-01-14
申请号：US16540606
申请日：2019-08-14
Applicant: Inscripta, Inc.
Inventor： Don Masquelier , Phillip Belgrader , Andrew Garst , Richard Fox , Matthew Estes , Bruce Chabansky
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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公开(公告)号：US11787841B2
公开(公告)日：2023-10-17
申请号：US17319006
申请日：2021-05-12
Applicant: Inscripta, Inc.
Inventor： Eric Abbate , Katherine Krouse , Richard Fox , Daniel Held , Michael Clay , Nandini Krishnamurthy
IPC: A61K39/108 , C07K14/245
CPC classification number: C07K14/245 , A61K39/0258
Abstract: The present disclosure relates to various different types of mutations in the thrA gene in E. coli leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
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49.发明授权公开(公告)号：US11739290B2
公开(公告)日：2023-08-29
申请号：US17555336
申请日：2021-12-17
Applicant: Inscripta, Inc.
Inventor： Andrew Garst , Richard Fox , Phillip Belgrader , Don Masquelier
IPC: C12M1/00 , C12M1/26 , C12N15/87 , C12M3/00 , C12N9/22 , C12N15/11 , C12N15/68 , C12N15/70 , C12N15/81 , C12N15/85 , C12N15/90 , C12N15/113 , B01D63/08 , B01D69/06 , B01D71/02 , C12N15/10
CPC classification number: C12M47/04 , C12M23/44 , C12M29/04 , C12M33/00 , C12M47/02 , C12N9/22 , C12N15/11 , C12N15/113 , C12N15/68 , C12N15/70 , C12N15/81 , C12N15/85 , C12N15/87 , C12N15/907 , B01D63/08 , B01D69/06 , B01D71/02 , B01D2201/0407 , C12N15/102 , C12N15/90 , C12N2310/20 , C12N2800/80 , C12N2830/001 , C12N2830/002
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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公开(公告)号：US20220290129A1
公开(公告)日：2022-09-15
申请号：US17199480
申请日：2021-03-12
Applicant: Inscripta, Inc.
Inventor： Richard Fox , Josh Shorenstein
Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.
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