Enhancements to the detection of pulmonary edema when using transthoracic impedance

    公开(公告)号:US20060258952A1

    公开(公告)日:2006-11-16

    申请号:US11126689

    申请日:2005-05-11

    IPC分类号: A61B5/05 A61B5/02 A61B7/00

    摘要: This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.

    Determining blood gas saturation based on measured parameter of respiration
    45.
    发明授权
    Determining blood gas saturation based on measured parameter of respiration 有权
    根据呼吸测量参数确定血气饱和度

    公开(公告)号:US07479114B2

    公开(公告)日:2009-01-20

    申请号:US11291480

    申请日:2005-12-01

    IPC分类号: A61B5/08

    摘要: Systems and methods provide for determining blood gas saturation based on one or more measured respiration parameters. A parameter of respiration is measured implantably over a duration of time. The measured respiratory parameter is associated with a blood gas saturation level. Blood gas saturation is determined based on the measured respiration parameter. At least one of associating the measured respiratory parameter and determining blood gas saturation is preferably preformed implantably.

    摘要翻译: 系统和方法提供了基于一个或多个测量的呼吸参数来确定血液气体饱和度。 在一段时间内可植入式地测量呼吸参数。 测量的呼吸参数与血气饱和度水平相关。 基于测量的呼吸参数确定血气饱和度。 关联测量的呼吸参数和确定血液气体饱和度中的至少一个优选地可植入地预先形成。

    Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods
    47.
    发明申请
    Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods 有权
    基于闭环阻抗的心脏再同步治疗系统,装置和方法

    公开(公告)号:US20060271119A1

    公开(公告)日:2006-11-30

    申请号:US11264941

    申请日:2005-11-02

    IPC分类号: A61N1/362

    摘要: This document discusses, among other things, systems, devices, and methods measure an impedance and, in response, adjust an atrioventricular (AV) delay or other cardiac resynchronization therapy (CRT) parameter that synchronizes left and right ventricular contractions. A first example uses parameterizes a first ventricular volume against a second ventricular volume during a cardiac cycle, using a loop area to create a synchronization fraction (SF). The CRT parameter is adjusted in closed-loop fashion to increase the SF. A second example measures a septal-freewall phase difference (PD), and adjusts a CRT parameter to decrease the PD. A third example measures a peak-to-peak volume or maximum rate of change in ventricular volume, and adjusts a CRT parameter to increase the peak-to-peak volume or maximum rate of change in the ventricular volume.

    摘要翻译: 本文件还讨论了系统,设备和方法测量阻抗,并作为响应调整房室(AV)延迟或同步左心室收缩和右心室收缩的其他心脏再同步治疗(CRT)参数。 第一个例子是使用循环区域创建同步分数(SF),在心动周期中使用第一心室容积对第二心室容积进行参数化。 CRT参数以闭环方式调整以增加SF。 第二个例子是测量隔层相位差(PD),并调整CRT参数以减少PD。 第三个例子测量心室容积的峰 - 峰体积或最大变化率,并调整CRT参数以增加心室容积的峰 - 峰体积或最大变化率。

    METHOD AND APPARATUS FOR TREATING IRREGULAR VENTRICULAR CONTRACTIONS SUCH AS DURING ATRIAL ARRHYTHMIA
    48.
    发明申请
    METHOD AND APPARATUS FOR TREATING IRREGULAR VENTRICULAR CONTRACTIONS SUCH AS DURING ATRIAL ARRHYTHMIA 有权
    方法和装置,用于治疗非正常血管造影,如阿司匹林

    公开(公告)号:US20070016258A1

    公开(公告)日:2007-01-18

    申请号:US11423516

    申请日:2006-06-12

    IPC分类号: A61N1/00

    摘要: A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.

    摘要翻译: 心律管理系统能够治疗不规则的心室心脏收缩,例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔(例如传感器指示的起搏间隔)来提供起搏疗法。 诸如无限脉冲响应(IIR)滤波器的加权平均器调节感测节拍的第一个起搏间隔,并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化,但是当心室节律稳定时,可抑制起搏。

    Method and apparatus for controlling cardiac therapy based on electromechanical timing
    49.
    发明申请
    Method and apparatus for controlling cardiac therapy based on electromechanical timing 有权
    基于机电定时控制心脏治疗的方法和装置

    公开(公告)号:US20060293714A1

    公开(公告)日:2006-12-28

    申请号:US11168024

    申请日:2005-06-28

    IPC分类号: A61N1/36

    摘要: Devices and methods for therapy control based on electromechanical timing involve detecting electrical activation of a patient's heart, and detecting mechanical cardiac activity resulting from the electrical activation. A timing relationship is determined between the electrical activation and the mechanical activity. A therapy is controlled based on the timing relationship. The therapy may improve intraventricular dyssynchrony of the patient's heart, or treat at least one of diastolic and systolic dysfunction and/or dyssynchrony of the patient's heart, for example. Electrical activation may be detected by sensing delivery of an electrical stimulation pulse to the heart or sensing intrinsic depolarization of the patient's heart. Mechanical activity may be detected by sensing heart sounds, a change in one or more of left ventricular impedance, ventricular pressure, right ventricular pressure, left atrial pressure, right atrial pressure, systemic arterial pressure and pulmonary artery pressure.

    摘要翻译: 基于机电定时的治疗控制的装置和方法涉及检测患者心脏的电激活,以及检测由电激活引起的机械心脏活动。 在电激活和机械活动之间确定时序关系。 基于时间关系控制治疗。 该治疗可以改善患者心脏的心室内不同步,或治疗患者心脏的舒张期和收缩功能障碍和/或不同步中的至少一种。 可以通过感测向心脏传递电刺激脉冲或感测患者心脏的固有去极化来检测电激活。 可以通过感测心脏声音,左心室阻抗,心室压力,右心室压力,左心房压力,右心房压力,全身动脉压力和肺动脉压力中的一个或多个的变化来检测机械活动。