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公开(公告)号:US10052612B2
公开(公告)日:2018-08-21
申请号:US14722119
申请日:2015-05-26
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Martin T. Gerber , Christopher M. Hobot
CPC classification number: B01J20/3475 , A61M1/1696 , B01J20/0211 , B01J20/3483 , B01J39/09
Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer or module of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include a fluid source containing at least one recharging fluid, wherein the fluid source is fluidly connectable to at least one rechargeable sorbent module for use in sorbent dialysis in a fluid flow path. The methods and apparatuses include passing a single solution through the zirconium phosphate for ion exchanges, resulting in zirconium phosphate to maintain a substantially consistent pH in a dialysate used during dialysis.
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公开(公告)号:US20180221554A1
公开(公告)日:2018-08-09
申请号:US15872363
申请日:2018-01-16
Applicant: Medtronic, Inc.
Inventor: Michael J. M. Mazack , Eric A. Grovender , Bryant J. Pudil
CPC classification number: A61M1/1603 , A61M1/1605 , A61M1/1607 , A61M1/1611 , A61M1/1613 , A61M1/1656 , A61M1/1696 , A61M1/267 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/3368 , A61M2205/3379 , A61M2205/50 , A61M2230/20
Abstract: The invention relates to devices, systems, and methods for managing base levels, specifically bicarbonate, in an individual undergoing dialysis. The devices, systems, and methods can be compatible with a sorbent-based dialysis therapy, and open loop control of base levels in the dialysis, without sensors or feedback for controlling the introduction of bicarbonate into the dialysate. The bicarbonate levels can be controlled and personalized to a patient using certain predetermined patient parameters. Related systems, algorithms, and control systems are contemplated including the specific predetermined parameters predictive of post-dialysis bicarbonate levels.
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公开(公告)号:US09943780B2
公开(公告)日:2018-04-17
申请号:US14259665
申请日:2014-04-30
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Martin T. Gerber , David B. Lura , Thomas E. Meyer
CPC classification number: B01D15/203 , A61M1/1621 , A61M1/1696 , A61M1/367 , A61M2202/0468 , A61M2205/128 , A61M2205/3334 , B01D15/10 , B01J20/3416 , B01J20/3425 , B01J20/3433 , B01J20/3475 , B01J2220/62
Abstract: A module for optionally recharging sorbent materials in-line, including zirconium phosphate, with an optional bypass and conduits for a sorbent cartridge. The sorbent cartridge can have one or more modules contained therein having connectors connecting each of the modules. One or more of the modules can be reusable and the sorbent materials therein recharged.
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公开(公告)号:US09872949B2
公开(公告)日:2018-01-23
申请号:US15449015
申请日:2017-03-03
Applicant: Medtronic, Inc.
Inventor: Thomas E. Meyer , David B. Lura , Bryant J. Pudil , Martin T. Gerber
CPC classification number: A61M1/1621 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/165 , A61M1/1652 , A61M1/1656 , A61M1/1658 , A61M1/1664 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1676 , A61M1/169 , A61M1/1696 , A61M1/3413 , A61M1/3437 , A61M1/3609 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3649 , A61M1/365 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2209/06 , A61M2230/65
Abstract: Systems and methods for controlling fluid movement and volumes of fluid between a subject and a controlled compliant flow path. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the controlled compliant flow path. An extracorporeal flow path is in fluid communication with the controlled compliant flow path across a semi-permeable membrane where the extracorporeal flow path has a first terminal end and a second terminal end.
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公开(公告)号:US09827361B2
公开(公告)日:2017-11-28
申请号:US13837287
申请日:2013-03-15
Applicant: MEDTRONIC, INC.
Inventor: Bryant J. Pudil , Thomas E. Meyer , David B. Lura , Martin T. Gerber
CPC classification number: A61M1/1656 , A61M1/1605 , A61M1/1658 , A61M1/1668 , A61M1/1696 , A61M1/287 , A61M2205/3317 , A61M2205/7518 , G01N33/84
Abstract: A pH-buffer measurement system that has at least one source for modifying the pH of a fluid entering the system, the source selected from an acid source and a base source. The acid source adds an acid equivalent to provide an acid reacted fluid and the base source adds a base equivalent to provide a base reacted fluid. The source is in fluid communication with a flow path and a component for determining a fluid characteristic of the acid reacted fluid or the base reacted fluid. The fluid characteristic that is measured is any one of a gas phase pressure, an electrical conductivity, or thermal conductivity.
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公开(公告)号:US20170312415A1
公开(公告)日:2017-11-02
申请号:US15651369
申请日:2017-07-17
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Thomas E. Meyer , David B. Lura , Martin T. Gerber
Abstract: A sorbent based monitoring system for measuring the solute concentration of at least one component of a fluid. The system has a sorbent regeneration system for regeneration of the fluid and has a sorbent cartridge that has at least one material layer. The fluid is conveyed through the sorbent cartridge and contacts at least one sensor after having contacted at least one material layer.
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公开(公告)号:US20150367055A1
公开(公告)日:2015-12-24
申请号:US14642847
申请日:2015-03-10
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , SuPing Lyu , Eric Grovender , Christopher M. Hobot , Martin T. Gerber
CPC classification number: A61M1/1696 , B01J39/09 , C01B25/45
Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing combinations of acids, bases and salts through a module containing a rechargeable sorbent material such as zirconium phosphate in order to replace ions bound to the zirconium phosphate with hydrogen and sodium ions. The method allows for a customizable zirconium phosphate, with control over the ratios of sodium to hydrogen on the recharged zirconium phosphate.
Abstract translation: 提供吸附剂再充电的方法和相关设备。 用于再充电的方法和相关装置可以对吸附剂盒中的吸附剂材料例如磷酸锆的特定可再充电层进行再充电。 所述方法和装置包括通过含有可再充电的吸附剂材料如磷酸锆的模块来传递含有酸,碱和盐的组合的溶液,以便用氢和钠离子代替与磷酸锆结合的离子。 该方法允许可定制的磷酸锆,控制再充电的磷酸锆上钠与氢的比例。
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公开(公告)号:USD742527S1
公开(公告)日:2015-11-03
申请号:US29506361
申请日:2014-10-15
Applicant: Medtronic, Inc.
Designer: Martin T. Gerber , David B. Lura , Bryant J. Pudil , Thomas E. Meyer , Brian Mullins
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公开(公告)号:US20150251162A1
公开(公告)日:2015-09-10
申请号:US14722119
申请日:2015-05-26
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Martin T. Gerber , Christopher M. Hobot
CPC classification number: B01J20/3475 , A61M1/1696 , B01J20/0211 , B01J20/3483 , B01J39/09
Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer or module of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include a fluid source containing at least one recharging fluid, wherein the fluid source is fluidly connectable to at least one rechargeable sorbent module for use in sorbent dialysis in a fluid flow path. The methods and apparatuses include passing a single solution through the zirconium phosphate for ion exchanges, resulting in zirconium phosphate to maintain a substantially consistent pH in a dialysate used during dialysis.
Abstract translation: 提供吸附剂再充电的方法和相关设备。 用于再充电的方法和相关装置可以对吸附剂盒中的吸附剂材料(例如磷酸锆)的特定可再充电层或模块进行再充电。 所述方法和装置包括含有至少一个再充电流体的流体源,其中所述流体源可流体连接至至少一个可再充电吸附剂模块,以用于流体流动路径中的吸附剂透析。 所述方法和装置包括使单一溶液通过磷酸锆进行离子交换,得到磷酸锆,以在透析期间使用的透析液中保持基本一致的pH。
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公开(公告)号:US20150083647A1
公开(公告)日:2015-03-26
申请号:US14555393
申请日:2014-11-26
Applicant: Medtronic, Inc.
Inventor: Thomas E. Meyer , David B. Lura , Bryant J. Pudil , Martin T. Gerber
CPC classification number: A61B50/10 , A61B2050/105 , A61M1/1656 , A61M1/1658 , A61M1/1666 , A61M1/1668 , A61M1/1696 , A61M1/3465 , A61M1/3646 , A61M1/3649 , A61M2202/0413 , A61M2205/121 , A61M2205/123 , A61M2205/126 , A61M2205/127 , A61M2205/14 , A61M2209/084
Abstract: A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session.
Abstract translation: 用于透析的便携式透析柜。 便携式透析柜可以具有尺寸和重量,其有助于容易地将柜从一个位置移动到另一个位置。 便携式透析柜可以具有促进便携性所必需的附加功能,例如轮子和手柄。 通常,便携式透析柜可以包含用于执行透析会话的所有必要组件。
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