公开(公告)号：US20060210595A1

公开(公告)日：2006-09-21

申请号：US11331849

申请日：2006-01-13

申请人： Rahul Singhvi ,  Amit Kumar ,  George Whitesides ,  Donald Ingber ,  Gabriel Lopez ,  Daniel Wang ,  Gregory Stephanopoulos

发明人： Rahul Singhvi ,  Amit Kumar ,  George Whitesides ,  Donald Ingber ,  Gabriel Lopez ,  Daniel Wang ,  Gregory Stephanopoulos

IPC分类号： A61F2/06 ,  A61F13/00

CPC分类号： C12N1/00 ,  B01J19/0046 ,  B01J2219/00382 ,  B01J2219/00385 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00617 ,  B01J2219/00619 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/0063 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/0072 ,  B81B2201/0214 ,  B81C1/00206 ,  B81C2201/034 ,  B82Y5/00 ,  B82Y30/00 ,  C12N5/0068 ,  C12N5/067 ,  C12N2535/10 ,  C12Q1/02 ,  C40B60/14

摘要： The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic islands that adhere cells, isolated by cytophobic regions to which cells do not adhere, contiguous with the cytophilic islands. The islands or the regions or both may be formed of a self-assembled monolayer (SAM).

公开(公告)号：US20060120358A1

公开(公告)日：2006-06-08

申请号：US11341408

申请日：2006-01-26

申请人： Anand Narasimhan ,  Yaacov Shemesh ,  Amit Kumar

发明人： Anand Narasimhan ,  Yaacov Shemesh ,  Amit Kumar

IPC分类号： H04L12/66

CPC分类号： H04L51/36 ,  H04L12/6418 ,  H04L51/00 ,  H04L2012/6424

摘要： A method and apparatus is disclosed for delivering messages that utilizes a message queue and a router/filter within a private data network. The private network is connected to an external data network such as the Internet, and has separate outbound resource servers to provide a high degree of scalability for handling a variety of message types.

摘要翻译： 公开了用于传送利用专用数据网络内的消息队列和路由器/过滤器的消息的方法和装置。 私有网络连接到诸如因特网之类的外部数据网络，并具有单独的出站资源服务器，以提供高度的可扩展性来处理各种消息类型。

公开(公告)号：US07033412B2

公开(公告)日：2006-04-25

申请号：US10669225

申请日：2003-09-24

申请人： Amit Kumar ,  John D. Ten Eyck ,  Thomas Lacki

发明人： Amit Kumar ,  John D. Ten Eyck ,  Thomas Lacki

IPC分类号： B01D35/30 ,  B01D46/00

CPC分类号： B01D46/0001 ,  B01D46/2422 ,  B01D46/2425 ,  B01D46/2451 ,  B01D46/2455 ,  B01D53/9454 ,  B01D2046/2496 ,  B01D2265/024 ,  B01D2279/30 ,  C03C3/06 ,  C03C13/005 ,  C03C25/66 ,  C03C2217/71 ,  F01N3/0211 ,  F01N3/2853 ,  F01N2330/06 ,  F01N2350/02 ,  Y02T10/20 ,  Y02T10/22 ,  Y10S55/30

摘要： A device (10) for treatment of exhaust gases includes a housing (12); a fragile structure (18) resiliently mounted within the housing (12); and a non-intumescent mounting mat (20) disposed in a gap between the housing (12) and the fragile structure (18). The mounting mat (20) comprises melt-formed, leached glass fibers high in silica content and exerts a minimum holding pressure for holding the fragile structure (18) within the housing (12) of one of (i) at least 10 kPa after 1000 cycles of testing at a hot face temperature of 900° C., a gap bulk density of between 0.3 and 0.5 g/cm3, and a percent gap expansion of 5 percent, and (ii) at least 50 kPa after 1000 cycles of testing at a hot face temperature of 300° C., a gap bulk density of between 0.3 and 0.5 g/cm3, and a percent gap expansion of 2 percent.

摘要翻译： 用于处理废气的装置（10）包括壳体（12）; 弹性地安装在所述壳体（12）内的脆弱结构（18）; 以及设置在所述壳体（12）和所述脆弱结构（18）之间的间隙中的非膨胀型安装垫（20）。 安装垫（20）包括熔融成型的二氧化硅含量高的沥滤玻璃纤维，并施加最小的保持压力，用于将易碎结构（18）保持在壳体（12）之中（i）中的至少10kPa之一（1000）之后 在900℃的热面温度下测试循环，间隙堆积密度为0.3-0.5g / cm 3，间隙膨胀百分比为5％，和（ii）至少 在300℃的热面温度下进行1000次循环试验后的50kPa，间隙体积密度为0.3〜0.5g / cm 3，间隙膨胀率为2％。

公开(公告)号：US20060085592A1

公开(公告)日：2006-04-20

申请号：US10957185

申请日：2004-09-30

申请人： Sumit Ganguly ,  Minos Garofalakis ,  Amit Kumar ,  Rajeev Rastogi

发明人： Sumit Ganguly ,  Minos Garofalakis ,  Amit Kumar ,  Rajeev Rastogi

IPC分类号： G06F12/14

CPC分类号： G06F17/30498 ,  G11C16/0416 ,  Y10S707/99943

摘要： The invention provides methods and systems for summarizing multiple continuous update streams using corresponding multiple (parallel) JD Sketch data structures such that, for example, an approximate answer to a query requiring a join operation followed by a duplicate elimination step may be rapidly provided.

摘要翻译： 本发明提供了使用对应的多个（并行）JD Sketch数据结构来概括多个连续更新流的方法和系统，使得例如可以快速地提供需要连接操作的跟踪操作的近似答案。

公开(公告)号：US20060002341A1

公开(公告)日：2006-01-05

申请号：US10879063

申请日：2004-06-30

申请人： Yigal Bejerano ,  Amit Kumar

发明人： Yigal Bejerano ,  Amit Kumar

IPC分类号： H04B7/212 ,  H04L12/56 ,  H04Q7/20

CPC分类号： H04W72/1236 ,  H04L45/12 ,  H04L45/46 ,  H04W40/10 ,  Y02D70/326

摘要： A more energy efficient, medium access control (MAC) layer of a multi-hop wireless network is provided using scheduling techniques which reduce packet collisions, and therefore the need for packet re-transmissions, while ensuring both bandwidth and delay, Quality-of-Service (QoS) guarantees. The techniques are used in conjunction with the formation of a multi-hop, configurable access wireless network (CAN).

摘要翻译： 使用减少分组冲突的调度技术提供多跳无线网络的更节能的媒体接入控制（MAC）层，并且因此在确保带宽和延迟的同时确保分组重传的需要， 服务（QoS）保证。 这些技术与多跳可配置接入无线网络（CAN）的形成结合使用。

公开(公告)号：US20060002302A1

公开(公告)日：2006-01-05

申请号：US10879062

申请日：2004-06-30

申请人： Yigal Bejerano ,  Amit Kumar

发明人： Yigal Bejerano ,  Amit Kumar

IPC分类号： H04L12/26 ,  H04Q7/24

CPC分类号： H04W92/02 ,  H04L45/02 ,  H04L45/42

摘要： Wireless stations (and their associated operation) making up a static, multi-hop wireless network are simplified because topological modeling and routing/scheduling decisions are shifted from the stations to a controller external to the network. The controller may determine routing paths and schedules for each of the wireless stations in a network based on the topology of a given network along with other network characteristics. Thereafter, the so-determined paths and schedules are sent to the associated wireless stations. By simplifying the operation of a wireless station, the amount of energy required to be used by each station may be reduced thereby maximizing the lifetime of the network.

摘要翻译： 由于拓扑建模和路由/调度决策从站点移动到网络外部的控制器，所以构成静态多跳无线网络的无线站（及其相关操作）被简化。 控制器可以基于给定网络的拓扑以及其他网络特性来确定网络中的每个无线站的路由路径和调度。 此后，将所确定的路径和时间表发送到相关联的无线站。 通过简化无线站的操作，可以减少每个站要使用的能量的量，从而最大化网络的使用寿命。

公开(公告)号：US06517778B1

公开(公告)日：2003-02-11

申请号：US09361391

申请日：1999-07-26

申请人： Amit Kumar ,  Larry Sheldon Jang ,  Danton Kai-Yu Leung ,  Richard Michele Rocco ,  Mark Charles Platshon

发明人： Amit Kumar ,  Larry Sheldon Jang ,  Danton Kai-Yu Leung ,  Richard Michele Rocco ,  Mark Charles Platshon

IPC分类号： G01N2147

CPC分类号： G01N21/03 ,  G01N21/6428 ,  G01N33/54366 ,  G01N33/552 ,  G01N33/94 ,  G01N35/00 ,  G01N2021/0346 ,  G01N2021/6482

摘要： A fluorescent immunoassay employing the interior surface of a capillary tube is provided. Devices to permit immunoassays using one or more capillary tubes, an apparatus for use with the devices, and a process for screening for analyte in a sample using the devices and apparatus are also provided. Samples suspected of containing analyte are added to a disposable self-contained sample tray containing one or more sample wells, mixed with a reagent, drawn into one or more spaced-apart capillary tubes held within a disposable cartridge connected to an analytical apparatus, reacted with a binding member on the surface of the capillary tube, washed to stop the reaction, and dried by the apparatus. The capillary tube is then exposed to a signal generation device to create a fluorescence signal that is detected using a signal detector. The apparatus determines the presence of the analyte and optionally determines the amount of analyte present in the sample, and presents the results to the operator.

公开(公告)号：US06368838B1

公开(公告)日：2002-04-09

申请号：US09373334

申请日：1999-08-12

申请人： Rahul Singhvi ,  Amit Kumar ,  George M. Whitesides ,  Donald E. Ingber ,  Gabriel P. Lopez ,  Daniel I. C. Wang ,  Gregory N. Stephanopoulos

发明人： Rahul Singhvi ,  Amit Kumar ,  George M. Whitesides ,  Donald E. Ingber ,  Gabriel P. Lopez ,  Daniel I. C. Wang ,  Gregory N. Stephanopoulos

IPC分类号： C12N1102

CPC分类号： C12N1/00 ,  B01J19/0046 ,  B01J2219/00382 ,  B01J2219/00385 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00617 ,  B01J2219/00619 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/0063 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/0072 ,  B81B2201/0214 ,  B81C1/00206 ,  B81C2201/034 ,  B82Y5/00 ,  B82Y30/00 ,  C12N5/0068 ,  C12N5/067 ,  C12N2535/10 ,  C12Q1/02 ,  C40B60/14

摘要： Methods and a device are provided for adhering cells in a specific and predetermined position. The device comprises a plate defining a surface and a plurality of cytophilic islands that adhere cells which are isolated by cytophobic regions to which cells do not adhere. The cytophobic regions can be wide enough such that less than 10 percent of the cells adhered to the cytophilic islands are allowed to form bridges across the cytophobic regions and contact each other. Further, the islands or the regions or both may be formed of a self-assembled monolayer (SAM). The methods are for forming a patterned surface for a population of cells and for selectively manipulating individual cells formed on the surface of the plate of the device. Furthermore, the device is used in immobilization of cells at a surface and for controlling shape of the cells.

摘要翻译： 提供了用于将细胞粘附在特定和预定位置的方法和装置。 该装置包括限定表面的板和附着由细胞不粘附细胞渗透区域分离的细胞的多个细胞色素岛。 细胞疏植区域可以足够宽，使得少于10％的细胞粘附到细胞色素岛被允许跨细胞疏漏区域形成桥接并彼此接触。 此外，岛或区域或两者可以由自组装单层（SAM）形成。 这些方法用于形成用于细胞群的图案化表面并且用于选择性地操纵形成在装置的板的表面上的单个细胞。 此外，该装置用于在表面固定细胞并用于控制细胞的形状。

公开(公告)号：US5976826A

公开(公告)日：1999-11-02

申请号：US951886

申请日：1997-10-16

申请人： Rahul Singhvi ,  Amit Kumar ,  George M. Whitesides ,  Donald E. Ingber ,  Gabriel P. Lopez ,  Daniel I. C. Wang ,  Gregory N. Stephanopoulos

发明人： Rahul Singhvi ,  Amit Kumar ,  George M. Whitesides ,  Donald E. Ingber ,  Gabriel P. Lopez ,  Daniel I. C. Wang ,  Gregory N. Stephanopoulos

IPC分类号： B01J19/00 ,  B81C1/00 ,  C12N5/00 ,  C12N5/02 ,  C12N5/071 ,  C40B60/14 ,  C12Q1/02 ,  C12N11/02 ,  C12N11/08 ,  C12Q1/04

CPC分类号： C12N5/067 ,  B01J19/0046 ,  B81C1/00206 ,  B82Y30/00 ,  B82Y5/00 ,  C12N5/0068 ,  B01J2219/00382 ,  B01J2219/00385 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00617 ,  B01J2219/00619 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/0063 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/0072 ,  B81B2201/0214 ,  B81C2201/034 ,  C12N2535/10 ,  C40B60/14

摘要： A device is provided for adhering cells in a specific and predetermined position. The device comprises a plate defining a surface and a plurality of cytophilic islands that adhere cells which are isolated by cytophobic regions to which cells do not adhere and further is contiguous with the cytophilic islands. The islands or the regions or both may be formed of a self-assembled monolayer (SAM). Further, the cytophobic regions are wide enough such that less than 10 percent of the cells adhered to the cytophilic islands are allowed to form bridges across the cytophobic regions and contact each other. The device is used in a method for culturing cells on a surface or in a medium and also for performing cytometry. Furthermore, the device is used in immobilization of cells at a surface and for controlling the shape of a cell.

摘要翻译： 提供了用于将细胞粘附在特定和预定位置的装置。 该装置包括限定表面的板和多个细胞亲和岛，所述细胞亲和岛附着细胞，细胞被细胞悬浮区域分离，细胞不粘附并进一步与细胞色素岛邻接。 岛或区域或两者可以由自组装单层（SAM）形成。 此外，细胞疏气区域足够宽，使得少于10％的细胞粘附到细胞色素岛被允许跨细胞疏漏区域形成桥接并彼此接触。 该装置用于在表面或培养基中培养细胞并用于进行细胞计数的方法。 此外，该装置用于在表面固定细胞并用于控制细胞的形状。

公开(公告)号：US5776748A

公开(公告)日：1998-07-07

申请号：US659537

申请日：1996-06-06

申请人： Rahul Singhvi ,  Amit Kumar ,  George M. Whitesides ,  Donald E. Ingber ,  Gabriel P. Lopez ,  Daniel I. C. Wang ,  Gregory N. Stephanopoulos

发明人： Rahul Singhvi ,  Amit Kumar ,  George M. Whitesides ,  Donald E. Ingber ,  Gabriel P. Lopez ,  Daniel I. C. Wang ,  Gregory N. Stephanopoulos

IPC分类号： B01J19/00 ,  B81C1/00 ,  C12N5/00 ,  C12N5/02 ,  C12N5/071 ,  C40B60/14 ,  B32B31/00 ,  C12N11/08 ,  C12N11/14

CPC分类号： C12N5/067 ,  B01J19/0046 ,  B81C1/00206 ,  B82Y30/00 ,  B82Y5/00 ,  C12N5/0068 ,  B01J2219/00382 ,  B01J2219/00385 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00617 ,  B01J2219/00619 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/0063 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/0072 ,  B81B2201/0214 ,  B81C2201/034 ,  C12N2535/10 ,  C40B60/14

摘要： The disclosed invention is a device for adhering cells in a specific and predetermined position. The device comprises a plate defining a surface and a plurality of cytophilic islands that adhere cells which are isolated by cytophobic regions to which cells do not adhere and further is contiguous with the cytophilic islands. The islands or the regions or both may be formed of a self-assembled monolayer (SAM). Further, the cytophobic regions are wide enough such that less than 10 percent of the cells adhered to the cytophilic islands are allowed to form bridges across the cytophobic regions and contact each other. The device is used in a method for culturing cells on a surface or in a medium and also for performing cytometry. Furthermore, the device is used in immobilization of cells at a surface and for controlling the shape of a cell.

摘要翻译： 所公开的发明是用于在特定和预定位置粘附电池的装置。 该装置包括限定表面的板和多个细胞亲和岛，所述细胞亲和岛附着细胞，所述细胞由细胞不粘附的细胞渗透区域分离，并且还与细胞色素岛连续。 岛或区域或两者可以由自组装单层（SAM）形成。 此外，细胞疏气区域足够宽，使得少于10％的细胞粘附到细胞色素岛被允许跨细胞疏漏区域形成桥接并彼此接触。 该装置用于在表面或培养基中培养细胞并用于进行细胞计数的方法。 此外，该装置用于在表面固定细胞并用于控制细胞的形状。