公开(公告)号：US20150065390A1

公开(公告)日：2015-03-05

申请号：US14394295

申请日：2012-04-20

Applicant: Alexandre M. Bratkovski ,  Zhiyong Li ,  Wei Wu ,  Min Hu ,  R. Stanley Williams ,  Ansoon Kim

Inventor： Alexandre M. Bratkovski ,  Zhiyong Li ,  Wei Wu ,  Min Hu ,  R. Stanley Williams ,  Ansoon Kim

IPC: G01N21/65 ,  G01N35/00 ,  B01L3/00

CPC classification number: G01N21/658 ,  B01L3/5088 ,  B01L2300/0627 ,  B01L2300/0819 ,  B01L2300/161 ,  G01N21/648 ,  G01N35/00009 ,  G01N2035/00019

Abstract: Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a substrate and a sensing member formed on a surface of the substrate. The sensing member includes collapsible signal amplifying structures and an area surrounding the collapsible signal amplifying structures that enables self-positioning of droplets exposed thereto toward the collapsible signal amplifying structures.

Abstract translation: 本文公开了集成传感器的示例。 集成传感器的示例包括形成在基板的表面上的基板和感测构件。 感测构件包括可折叠信号放大结构和围绕可折叠信号放大结构的区域，其使得能够将暴露于其的液滴自动定位到可折叠信号放大结构。

公开(公告)号：US20130217143A1

公开(公告)日：2013-08-22

申请号：US13879255

申请日：2010-10-20

Applicant: Zhiyong Li ,  R. Stanley Williams

Inventor： Zhiyong Li ,  R. Stanley Williams

IPC: G01N21/64

CPC classification number: G01N21/6428 ,  G01N21/648 ,  G01N21/658 ,  G01N33/54373

Abstract: A chemical-analysis device integrated with a metallic-nanofinger device for chemical sensing. The chemical-analysis device includes a metallic-nanofinger device, and a platform. The metallic-nanofinger device includes a substrate, and a plurality of nanofingers coupled with the substrate. A nanofinger of the plurality includes a flexible column, and a metallic cap coupled to an apex of the flexible column. At least the nanofinger and a second nanofinger of the plurality of nanofingers are to self-arrange into a close-packed configuration with at least one analyte molecule. A morphology of the metallic cap is to generate a shifted plasmonic-resonance peak associated with amplified luminescence from the analyte molecule. A method for using, and a chemical-analysis apparatus including the chemical-analysis device are also provided.

公开(公告)号：US08502198B2

公开(公告)日：2013-08-06

申请号：US11414578

申请日：2006-04-28

Applicant: R. Stanley Williams ,  Zhiyong Li ,  Douglas Ohlberg ,  Philip J. Kuekes ,  Duncan Stewart

Inventor： R. Stanley Williams ,  Zhiyong Li ,  Douglas Ohlberg ,  Philip J. Kuekes ,  Duncan Stewart

IPC: H01L29/08

CPC classification number: G11C13/02 ,  G11C13/0009 ,  G11C2213/77 ,  H01L51/0591

Abstract: A switching device includes at least one bottom electrode and at least one top electrode. The top electrode crosses the bottom electrode at a non-zero angle, thereby forming a junction. A metal oxide layer is established on at least one of the bottom electrode or the top electrode. A molecular layer including a monolayer of organic molecules and a source of water molecules is established in the junction. Upon introduction of a forward bias, the molecular layer facilitates a redox reaction between the electrodes, thereby reducing a tunneling gap between the electrodes.

Abstract translation: 开关装置包括至少一个底部电极和至少一个顶部电极。 顶部电极以非零角度穿过底部电极，从而形成结。 在底电极或顶电极中的至少一个上建立金属氧化物层。 在连接处建立了包括有机分子单层和水分子源的分子层。 在引入正向偏压时，分子层促进电极之间的氧化还原反应，从而减少电极之间的隧道间隙。

公开(公告)号：US20130037773A1

公开(公告)日：2013-02-14

申请号：US13383616

申请日：2010-04-30

Applicant: Dmitri B. Strukov ,  Alexandre M. Bratkovski ,  R. Stanley Williams ,  Zhiyong Li

Inventor： Dmitri B. Strukov ,  Alexandre M. Bratkovski ,  R. Stanley Williams ,  Zhiyong Li

IPC: H01L45/00

CPC classification number: H01L45/08 ,  G02F1/13471 ,  H01L45/085 ,  H01L45/14 ,  H01L45/142 ,  H01L45/146

Abstract: An ionic device includes a layer (220) of an ionic conductor containing first and second species (222, 224) of impurities. The first species (222) of impurity in the layer (220) is mobile in the ionic conductor, and a concentration profile of the first species (222) determines a functional characteristic of the device (200). The second species (224) of impurity in the layer (220) interacts with the first species (222) within the layer (220) to create a structure (226) that limits mobility of the first species (222) in the layer (220).

Abstract translation: 离子装置包括含有杂质的第一和第二物质（222,224）的离子导体层（220）。 层（220）中的第一杂质物质（222）在离子导体中是可移动的，并且第一物质（222）的浓度分布决定了装置（200）的功能特征。 层（220）中的杂质的第二物质（224）与层（220）内的第一物质（222）相互作用以产生限制层（220）中第一物质（222）的迁移率的结构（226） ）。

公开(公告)号：US20120154791A1

公开(公告)日：2012-06-21

申请号：US12846524

申请日：2010-07-29

Applicant: Huei Pei Kuo ,  Zhiyong Li ,  R. Stanley Williams

Inventor： Huei Pei Kuo ,  Zhiyong Li ,  R. Stanley Williams

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01J3/0227 ,  G01J3/26 ,  G01J3/36 ,  G01N21/658

Abstract: A surface enhanced Raman spectroscopy system includes a surface enhanced Raman spectroscopy substrate and a laser source configured to emit light within a spectrum of wavelengths toward a predetermined species on or near the surface enhanced Raman spectroscopy substrate. The system further includes a set of filters positioned to be in optical communication with light scattered after the laser light interacts with the predetermined species. Each of the filters in the set is respectively configured to pass scattered light within a different predetermined narrow band of wavelengths. The system also includes a plurality of photodetectors, where each photodetector is positioned adjacent to a respective one of the filters in the set and is configured to output a signal if the scattered light passes through the respective one of the filters. The set of filters is targeted for detection of characteristic peaks of the predetermined species.

Abstract translation: 表面增强拉曼光谱系统包括表面增强拉曼光谱基板和激光源，该激光源被配置为向表面增强拉曼光谱基板上或附近的预定物质发射波长光谱的光。 该系统还包括一组滤光器，其被定位成在激光与预定物质相互作用之后与散射的光光通信。 集合中的每个滤光器分别被配置成使不同预定的窄波段内的散射光通过。 该系统还包括多个光电检测器，其中每个光电检测器被定位成与集合中的相应一个滤光器相邻，并且被配置为如果散射光通过相应的一个滤光器则输出信号。 该组滤波器用于检测预定种类的特征峰。

公开(公告)号：US20110267611A1

公开(公告)日：2011-11-03

申请号：US12772161

申请日：2010-04-30

Applicant: Zhiyong Li ,  David A. Fattal ,  Jingjing Li ,  R. Stanley Williams

Inventor： Zhiyong Li ,  David A. Fattal ,  Jingjing Li ,  R. Stanley Williams

IPC: G01J3/44 ,  G01J3/00

CPC classification number: G01J3/44 ,  G01J3/1895 ,  G01N21/658

Abstract: A scattering spectroscopy apparatus, system and method employ guided mode resonance (GMR) and a GMR grating. The apparatus includes a GMR grating having a subwavelength grating, and an optical detector configured to receive a portion of a scattered signal produced by an interaction between an excitation signal and an analyte associated with a surface of the GMR grating. A propagation direction of the received portion of the scattered signal is substantially different from a propagation direction of a GMR-coupled portion of the excitation signal within the GMR grating. The system includes the apparatus and an optical source. The method includes exciting a GMR in a GMR grating, interacting a GMR-coupled portion of the excitation signal with an analyte to produce a scattered signal and detecting a portion of the scattered signal.

Abstract translation: 散射光谱装置，系统和方法采用导模共振（GMR）和GMR光栅。 该装置包括具有亚波长光栅的GMR光栅和配置成接收由激发信号与与GMR光栅的表面相关联的分析物之间的相互作用产生的散射信号的一部分的光学检测器。 散射信号的接收部分的传播方向与GMR光栅内的激励信号的GMR耦合部分的传播方向基本上不同。 该系统包括该装置和光源。 该方法包括激励GMR光栅中的GMR，将激发信号的GMR耦合部分与分析物相互作用以产生散射信号并检测散射信号的一部分。

公开(公告)号：US07532119B2

公开(公告)日：2009-05-12

申请号：US11269237

申请日：2005-11-08

Applicant: Alexandre M. Bratkovski ,  Zhiyong Li ,  Geoffrey Lyon ,  Philip Kuekes ,  Shih Yuang Wang ,  R. Stanley Williams

Inventor： Alexandre M. Bratkovski ,  Zhiyong Li ,  Geoffrey Lyon ,  Philip Kuekes ,  Shih Yuang Wang ,  R. Stanley Williams

IPC: G08B13/14

CPC classification number: G06K7/0008 ,  H04L67/12

Abstract: A multi-tiered network for gathering detected condition information includes a first tier having first tier nodes and a second tier having a second tier node. The second tier node is operable to receive detected condition information from at least one of the first tier nodes in a substantially autonomous manner. In addition, the second tier node is operable to at least one of store, process, and transmit the detected condition information. The network also includes a third tier having a third tier node configured to receive the detected condition information and to at least one of store and process the detected condition information.

Abstract translation: 用于收集检测到的条件信息的多层网络包括具有第一层节点的第一层和具有第二层节点的第二层。 第二层节点可操作以基本上自主的方式从至少一个第一层节点接收检测到的条件信息。 此外，第二层节点可操作以存储，处理和发送检测到的条件信息中的至少一个。 网络还包括第三层，其具有被配置为接收检测到的条件信息的第三层节点以及存储和处理检测到的条件信息中的至少一个。

公开(公告)号：US10520440B2

公开(公告)日：2019-12-31

申请号：US14377524

申请日：2012-02-08

Applicant: Devin Alexander Mourey ,  James William Stasiak ,  James Elmer Abbott, Jr. ,  Zhiyong Li

Inventor： Devin Alexander Mourey ,  James William Stasiak ,  James Elmer Abbott, Jr. ,  Zhiyong Li

IPC: G01J3/44 ,  G01N21/65

Abstract: Molecule sensing apparatus. The apparatus has first and second chambers, an input port extending into the first chamber, a fluid channel extending from the first chamber to the second chamber, and a surface-enhanced substrate in the second chamber.

公开(公告)号：US09709538B2

公开(公告)日：2017-07-18

申请号：US14239330

申请日：2011-09-30

Applicant: Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

Inventor： Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

IPC: G01N31/22 ,  G01N21/64 ,  G01N21/65 ,  B01L3/00 ,  B82Y15/00

CPC classification number: G01N31/22 ,  B01L3/5085 ,  B01L3/50853 ,  B01L2200/141 ,  B01L2300/0636 ,  B01L2300/069 ,  B01L2300/0819 ,  B82Y15/00 ,  G01N21/648 ,  G01N21/658 ,  G01N2201/0227 ,  G01N2201/023 ,  Y10T436/25

Abstract: Devices to detect a substance and methods of producing such a device are disclosed. An example device to detect a substance includes a housing defining an externally accessible chamber and a seal to enclose at least a portion of the chamber. The example device also includes a substrate includes nanoparticles positioned within the chamber. The nanoparticles to react to the substance when exposed thereto. The example device also includes a non-analytic solution within the chamber to protect the nanoparticles from premature exposure.

公开(公告)号：US09592001B2

公开(公告)日：2017-03-14

申请号：US14406601

申请日：2012-07-29

Applicant: Steven Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Gary Gibson

Inventor： Steven Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Gary Gibson

IPC: G01J3/44 ,  A61B5/1459 ,  G01N21/65 ,  A61B5/00

CPC classification number: A61B5/1459 ,  A61B5/0075 ,  A61B5/6862 ,  G01N21/658

Abstract: An implantable nanosensor includes a stent to be implanted inside a fluid conduit. The stent has a well in a surface of the stent. The implantable nanosensor further includes a nanoscale-patterned sensing substrate disposed in the well. The nanoscale-patterned sensing substrate is to produce an optical scattering response signal indicative of a presence of an analyte in a fluid carried by the fluid conduit when interrogated by an optical stimulus signal.

Abstract translation: 可植入纳米传感器包括待植入流体导管内的支架。 支架在支架表面有一个井。 可植入纳米传感器还包括设置在井中的纳米级图案感测基片。 纳米级图案化感测衬底将产生光学散射响应信号，该信号指示由光学刺激信号询问时由流体导管携带的流体中分析物的存在。