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148 条记录 (耗时 0.042 秒)

    Shoe with optimal mass distribution
    41.
    发明申请
    Shoe with optimal mass distribution 有权
    鞋子具有最佳质量分布

    公开(公告)号：US20070022633A1

    公开(公告)日：2007-02-01

    申请号：US11541825

    申请日：2006-10-02

    申请人： Roland Seydel ,  Wolfgang Scholz

    发明人： Roland Seydel ,  Wolfgang Scholz

    IPC分类号： A43B5/02 ,  A43B5/00

    CPC分类号： A43B7/1455 ,  A43B5/02 ,  A43B13/14 ,  A43B19/005 ,  A43C13/02 ,  A43C15/16

    摘要： Disclosed is a shoe including an upper for receiving a foot and a sole unit with a heel region and forefoot region, wherein an additional weight is arranged in at least one of the forefoot region and the heel region of the sole unit to stabilize the foot against at least one torque acting on a wearer's foot.

    摘要翻译： 公开了一种鞋，其包括用于接收脚的鞋面和具有脚后跟区域和前脚区域的鞋底单元，其中，在鞋底单元的前脚掌区域和脚后跟区域中的至少一个中布置附加重量，以使鞋脚抵抗 至少一个作用在使用者脚上的扭矩。

    Detection, prevention, and treatment systems for anthrax
    42.
    发明申请
    Detection, prevention, and treatment systems for anthrax 审中-公开
    炭疽检测，预防和治疗系统

    公开(公告)号：US20050281830A1

    公开(公告)日：2005-12-22

    申请号：US11041471

    申请日：2005-01-24

    申请人： Phillip Morrow ,  Jeanne Morrow ,  Angray Kang ,  Fei Wang ,  Ivy Jiang ,  Ritsuko Sawada ,  Wolfgang Scholz

    发明人： Phillip Morrow ,  Jeanne Morrow ,  Angray Kang ,  Fei Wang ,  Ivy Jiang ,  Ritsuko Sawada ,  Wolfgang Scholz

    IPC分类号： A61K39/40 ,  G01N33/554 ,  G01N33/569

    CPC分类号： G01N33/6854 ,  A61K39/395 ,  A61K45/06 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/1278 ,  C07K2317/21 ,  G01N2333/35 ,  A61K2300/00

    摘要： A highly efficient method for generating human antibodies using recall technology is provided. In one aspect, human antibodies which are specific to the anthrax toxin are provided. In one aspect, human peripheral blood cells that have been pre-exposed to anthrax toxin are used in the SCID mouse model. This method results in high human antibody titers which are primarily of the IgG isotype and which contain antibodies of high specificity and affinity to desired antigens. The antibodies generated by this method can be used therapeutically and prophylactically for preventing or treating mammals exposed to anthrax. Thus, in one embodiment, a prophylactic or therapeutic agent used to counter the effects of anthrax toxin, released as a mechanism of bioterrorism, is provided. In one embodiment, a formulation and method for preventing and/or treating anthrax infection comprising a binding agent that prevents the assembly of the PA63 heptamer is also provided. Methods for diagnosis and methods to determine anthrax contamination are also described.

    摘要翻译： 提供了使用召回技术产生人抗体的高效方法。 一方面，提供了对炭疽毒素特异性的人抗体。 一方面，在SCID小鼠模型中使用预先暴露于炭疽毒素的人外周血细胞。 该方法导致高的人抗体滴度，其主要是IgG同种型，并且其含有对所需抗原具有高特异性和亲和力的抗体。 通过该方法产生的抗体可以治疗和预防用于预防或治疗暴露于炭疽的哺乳动物。 因此，在一个实施方案中，提供了用作抵抗作为生物恐怖机制的机制释放的炭疽毒素的作用的预防或治疗剂。 在一个实施方案中，还提供了用于预防和/或治疗炭疽感染的制剂和方法，其包含防止PA63七聚体组装的结合剂。 还描述了诊断方法和确定炭疽污染的方法。

    Differential pressure sensor
    44.
    发明授权
    Differential pressure sensor 失效
    差压传感器

    公开(公告)号：US06640640B2

    公开(公告)日：2003-11-04

    申请号：US10172235

    申请日：2002-06-14

    申请人： Wolfgang Scholz ,  Albrecht Vogel ,  Peter Krippner

    发明人： Wolfgang Scholz ,  Albrecht Vogel ,  Peter Krippner

    IPC分类号： G01L1500

    CPC分类号： G01L19/0618 ,  G01L9/0055 ,  G01L9/0073 ,  G01L13/026

    摘要： A differential pressure sensor has a first and a second measuring chamber. Each measuring chamber is limited by a rigid carrier plate and a diaphragm plate, which is formed in the region of the measuring chamber as a pressure-sensitive measuring diaphragm. To design the differential pressure sensor to be resistant to overloading, the carrier plate is arranged between a first and a second diaphragm plate and has congruent concave depressions on opposite sides in the plane of the plate. The depressions are connected to one another by a central duct, penetrating the carrier plate perpendicularly to the plane of the plates. In the region of the measuring chambers, the diaphragm plates are formed congruently in relation to the depressions as pressure-sensitive measuring diaphragms. The measuring chambers are coupled to one another by a ram guided axially movably in the duct.

    摘要翻译： 差压传感器具有第一和第二测量室。 每个测量室由刚性载体板和隔膜板限制，该板在测量室的区域中形成为压敏测量膜片。 为了设计差压传感器以防止过载，承载板布置在第一和第二隔膜板之间，并且在板的平面的相对侧上具有一致的凹陷。 凹陷通过中心导管彼此连接，垂直于板的平面穿过载体板。 在测量室的区域中，隔板相对于凹陷形成为压敏测量隔膜。 测量室通过在管道中可轴向移动的冲头彼此联接。

    Transportable modular patient monitor with data acquisition modules
    45.
    发明授权
    Transportable modular patient monitor with data acquisition modules 失效
    带数据采集模块的可运输模块化病人监护仪

    公开(公告)号：US06221012B1

    公开(公告)日：2001-04-24

    申请号：US08369853

    申请日：1995-01-06

    申请人： Michael Maschke ,  Thomas Bishop ,  Bengt Hermanrud ,  Wolfgang Scholz ,  Clifford Mark Kelly

    发明人： Michael Maschke ,  Thomas Bishop ,  Bengt Hermanrud ,  Wolfgang Scholz ,  Clifford Mark Kelly

    IPC分类号： A61B502

    CPC分类号： A61B5/002 ,  A61B5/7445 ,  G06F19/00 ,  G06F19/3418 ,  G06Q50/24 ,  G16H10/60 ,  G16H40/40 ,  G16H40/63

    摘要： Patient monitoring apparatus for use in an environment which includes a plurality of sensors. The apparatus provides collection and display of patient data signals collected from a medical patient using the sensors, including periods when the patient is being transported. The apparatus comprises a portable monitor coupled to a plurality of distinct data acquisition modules, which are coupled to the sensors. The modules includes cartridges, which detachably mount to the portable monitor, and pods which are positioned independent of the monitor. The pods reduce the number of cables extending between the patient's bed and the portable monitor by combining signals from many sensors into a single output signal. The modules collect patient data in analog form from the sensors and provide digital data signals to the monitor. The portable monitor includes: a display device for displaying the patient data, and storage for the patient data. The portable monitor may be coupled to a docking station. The portable monitor receives power from the docking station, and transfers data to a remote display device by way of the docking station. Patient data is displayed on either one of the portable monitor or the remote display device. A battery pack and a hardcopy output device attach to the case of the portable monitor.

    摘要翻译： 用于包括多个传感器的环境中的患者监护装置。 该装置提供使用传感器从医疗病人收集的患者数据信号的收集和显示，包括患者被运送的时期。 该装置包括耦合到多个不同数据采集模块的便携式监视器，其耦合到传感器。 模块包括可拆卸地安装到便携式监视器的盒，以及独立于监视器定位的盒。 荚通过将来自许多传感器的信号组合成单个输出信号来减少患者床和便携式监视器之间延伸的电缆数量。 模块以传感器的模拟形式收集患者数据，并向监护仪提供数字数据信号。 便携式监视器包括：用于显示患者数据的显示装置和用于患者数据的存储。 便携式监视器可以耦合到对接站。 便携式监视器从对接站接收电力，并通过对接站将数据传送到远程显示设备。 患者数据显示在便携式监视器或远程显示设备的任一个上。 电池组和硬拷贝输出设备连接到便携式显示器的外壳。

    Microcellular urea-containing polyurethane elastomer
    47.
    发明授权
    Microcellular urea-containing polyurethane elastomer 失效
    含微孔尿素的聚氨酯弹性体

    公开(公告)号：US6063824A

    公开(公告)日：2000-05-16

    申请号：US91697

    申请日：1998-11-18

    申请人： Ruediger Krech ,  Udo Rotermund ,  Heinz Bollmann ,  Renate Hempel ,  Wolfgang Scholz ,  Manfred Genz

    发明人： Ruediger Krech ,  Udo Rotermund ,  Heinz Bollmann ,  Renate Hempel ,  Wolfgang Scholz ,  Manfred Genz

    IPC分类号： C08J9/36 ,  C08G18/08 ,  C08G18/40 ,  C08G18/76 ,  C08G101/00 ,  C08J9/04

    CPC分类号： C08G18/089 ,  C08G18/7664 ,  C08G2101/0066 ,  C08G2101/0083 ,  C08G2350/00

    摘要： A microcellular PU elastomer having improved dynamic-mechanical properties and based on an isocyanate component consisting essentially of 4,4'-MDI and also further customary constituents has, after heating at from 100 to 120.degree. C. for from 8 to 24 hours, a melting range of from 130.degree. C. as the minimum lower limit to 230.degree. C. as a minimum upper limit, measured by differential scanning calorimetry (DSC) at a heating rate of 20.degree. C./min, and a urea content of from 14 to 18% by weight.A process is also provided for preparing such a microcellular PU elastomer having improved dynamic mechanical properties. The microcellular PU elastomers can be used for producing damping elements.

    摘要翻译： PCT No.PCT / EP96 / 05639 Sec。 371日期：1998年11月18日 102（e）1998年11月18日日期PCT 1996年12月16日PCT公布。 公开号WO97 / 23534 日期1997年7月3日具有改进的动态力学性能并且基于由4,4'-MDI组成的异氰酸酯组分的微孔PU弹性体以及另外的常规组分在100至120℃下加热8 至20小时，通过差示扫描量热法（DSC）以20℃/分钟的加热速率测量的最小下限为230℃的熔点为最小上限，为最小上限，以及 尿素含量为14至18重量％。 还提供了一种制备这种具有改进的动态力学性能的微孔PU弹性体的方法。 微孔PU弹性体可用于制造阻尼元件。