利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

93 条记录 (耗时 0.035 秒)

    Process for the preparation of 21-halogeno-21-desoxy-17.alpha.-acyloxy-20-keto-pregnenes
    43.
    发明授权
    Process for the preparation of 21-halogeno-21-desoxy-17.alpha.-acyloxy-20-keto-pregnenes 失效
    制备21-脱氧-21-脱氧-17 {6-酰基-20-酮 - 孕烯的方法

    公开(公告)号：US3992422A

    公开(公告)日：1976-11-16

    申请号：US604672

    申请日：1975-08-14

    申请人： Michael J. Green

    发明人： Michael J. Green

    IPC分类号： C07J7/00 ,  C07J21/00 ,  C07J51/00 ,  C07J5/00

    CPC分类号： C07J51/00 ,  C07J21/00 ,  C07J7/0085

    摘要： 21-Halogeno-17.alpha.-acyloxy-20-keto-4-pregnenes having physiological properties are prepared by the reaction of a 17.alpha.,21-dihydroxy-20-keto-4-pregnene 17.alpha.,21-orthoester with a halide reagent selected from the group consisting of triarylsilyl halides and tri-lower alkylsilyl halides in an organic solvent, said halide being chloride or bromide. Preferred reagents are tri-lower alkylsilyl halides, particularly trimethylsilyl chloride.

    摘要翻译： 具有生理特性的21-卤代-17α-酰氧基-20-酮-4-孕烯通过17α，21-二羟基-20-酮-4-孕烯17α，21-原酸酯与卤化物试剂 选自三芳基甲硅烷基卤化物和三低级烷基甲硅烷基卤化物在有机溶剂中，所述卤化物是氯化物或溴化物。 优选的试剂是三低级烷基甲硅烷基卤化物，特别是三甲基甲硅烷基氯。

    Process for the preparation of 21-desoxy-17-acyloxy-4-pregnenes and of 21-iodo-21-desoxy-17-acyl oxy-4-pregnene intermediates useful therein
    44.
    发明授权
    Process for the preparation of 21-desoxy-17-acyloxy-4-pregnenes and of 21-iodo-21-desoxy-17-acyl oxy-4-pregnene intermediates useful therein 失效
    制备21-脱氧-17-酰氧基-4-孕烯的方法和其中有用的21-碘-21-脱氧-17-酰基氧-4-孕烯中间体

    公开(公告)号：US3980680A

    公开(公告)日：1976-09-14

    申请号：US604671

    申请日：1975-08-14

    申请人： Michael J. Green

    发明人： Michael J. Green

    IPC分类号： C07J7/00 ,  C07J21/00 ,  C07J5/00

    CPC分类号： C07J7/0055 ,  C07J21/00 ,  C07J7/0045

    摘要： 21-Desoxy-17.alpha.-acyloxy-20-keto-4-pregnenes having physiological properties are prepared by the reaction of a 17.alpha.,21-dihydroxy-20-keto-4-pregnene 17.alpha.,21-orthoester or a 21-iodo-21-desoxy-17.alpha.-acyloxy-20-keto-4-pregnene with an iodide reagent selected from the group consisting of triphenylsilyl iodide, tri-lower alkylsilyl iodide and triphenylmethyl iodide. When said 17.alpha.,21-dihydroxy-20-keto-4-pregnene 17.alpha.,21-orthoester is reacted with less than two molar equivalents of a tri-lower alkylsilyl iodide reagent there is also formed a 21-iodo-21-desoxy-17-.alpha. -acyloxy-20-keto-4-pregnene, a useful intermediate, which, upon reaction with additional iodide reagent, is converted to the corresponding 21-desoxy-17.alpha.-acyloxy-20-keto-4-pregnene.

    摘要翻译： 具有生理特性的21-脱氧-17α-酰氧基-20-酮-4-孕烯通过17α，21-二羟基-20-酮-4-孕烯17α，21-原酸酯或21- 碘代-21-脱氧-17α-酰氧基-20-酮-4-孕烯与碘化物试剂，选自三苯基甲硅烷基碘，三低级烷基甲硅烷基碘和三苯基甲基碘。 当所述17α，21-二羟基-20-酮-4-孕烯17α，21-原酸酯与少于2摩尔当量的三低级烷基甲硅烷基碘试剂反应时，还形成了21-碘-21-脱氧 -17-α-酰氧基-20-酮-4-孕烯，一种有用的中间体，其在与另外的碘化物试剂反应后转化为相应的21-脱氧-17α-酰基氧基-20-酮-4-孕烯。

    (17R)-Spiro-[androstane-17,1'-cyclobutan]-2'-ones, methods for their manufacture and intermediates useful therein
    45.
    发明授权
    (17R)-Spiro-[androstane-17,1'-cyclobutan]-2'-ones, methods for their manufacture and intermediates useful therein 失效
    （17R）-Siro- {8雄甾烷-17,1 {40-环丁烷{9-2 {40-酮，其制造方法和其中有用的中间体

    公开(公告)号：US3968132A

    公开(公告)日：1976-07-06

    申请号：US535387

    申请日：1974-12-23

    申请人： Michael J. Green ,  Ho-Jane Shue

    发明人： Michael J. Green ,  Ho-Jane Shue

    IPC分类号： C07J1/00 ,  C07J21/00 ,  C07J53/00 ,  C07J5/00

    CPC分类号： C07J53/001 ,  C07J1/0011 ,  C07J21/003 ,  C07J53/007

    摘要： (17R)-Spiro-[androstane-17,1'-cyclobutan]-2'-ones are prepared by the reaction of a 17-oxo androstane, wherein all other ketones are blocked, with a cyclopropylarylsulfide or with a cyclopropylarylsulfonium salt having a non-nucleophilic anion, in an organic solvent together with a strong base, followed by reaction in situ of the intermediate thereby formed with aqueous acid or water.Some (17R)-spiro-[androstan-17,1'-cyclobutan]-2'-ones are useful as intermediates in preparing (17R)-spiro-[3-oxo-4-androstene-17,1'-cyclobutan]-2'-ones which are aldosterone antagonists. Additionally, (17R)-spiro-[androstane-17,1'-cyclobutan]-2'-ones are useful as intermediates in preparing known 17.alpha.-pregnane-21,17.beta.-carbolactones, valuable aldosterone blocking agents.

    摘要翻译： （17R）-Siro- [雄甾烷-17,1'-环丁烷] -2'-酮通过与环丙基芳基硫醚或具有环丙基芳基锍盐的17-氧代雄甾烷（其中所有其它酮被封闭）的反应制备， 非亲核阴离子，在有机溶剂中与强碱一起，随后由中间体原位反应，由此与酸或水的水溶液形成。

    Interface module for use with a Modbus device network and a Fieldbus device network
    48.
    发明授权
    Interface module for use with a Modbus device network and a Fieldbus device network 有权
    用于Modbus设备网络和现场总线设备网络的接口模块

    公开(公告)号：US07246193B2

    公开(公告)日：2007-07-17

    申请号：US10354525

    申请日：2003-01-30

    申请人： Eric D. Rotvold ,  Donald R. Lattimer ,  Michael J. Green ,  Robert J. Karschnia ,  Marcos A. V. Peluso

    发明人： Eric D. Rotvold ,  Donald R. Lattimer ,  Michael J. Green ,  Robert J. Karschnia ,  Marcos A. V. Peluso

    IPC分类号： G06F13/36 ,  G06F13/20 ,  G06F13/10 ,  G06F13/40

    CPC分类号： G05B19/4186 ,  G05B2219/31122 ,  G05B2219/31326 ,  G05B2219/31335 ,  Y02P90/185

    摘要： An interface module is operatively coupled to a Fieldbus process control network and a Modbus process control network to facilitate the exchange of process control information between the networks. The interface module stores a register map database in which the process control parameters of the function blocks in the field devices of the Fieldbus process control network are mapped to register numbers of the Modbus process control network. Once the Fieldbus process control parameters are mapped to the Modbus registers, the interface module is adapted to transmit request messages on the Fieldbus process control network to the Fieldbus field devices for the current values of the process control parameters, receive response messages from the Fieldbus field devices, and store the current values of the process control parameters in the register map database.

    摘要翻译： 接口模块可操作地耦合到现场总线过程控制网络和Modbus过程控制网络，以便于在网络之间交换过程控制信息。 接口模块存储寄存器映射数据库，其中现场总线过程控制网络的现场设备中功能块的过程控制参数映射到Modbus过程控制网络的寄存器编号。 将现场总线过程控制参数映射到Modbus寄存器后，接口模块适用于在现场总线过程控制网络上向现场总线现场设备发送请求消息，以获取过程控制参数的当前值，从现场总线字段接收响应消息 设备，并将过程控制参数的当前值存储在寄存器映射数据库中。

    Spa control system
    49.
    发明授权
    Spa control system 失效

    公开(公告)号：US06965815B1

    公开(公告)日：2005-11-15

    申请号：US10043799

    申请日：2002-01-09

    申请人： Michael E. Tompkins ,  Michael J. Green

    发明人： Michael E. Tompkins ,  Michael J. Green

    IPC分类号： G05D23/00 ,  G05D23/19

    CPC分类号： G05D23/1917

    摘要： An improved spa control system is disclosed. The invention describes a spa control system which calculates the time required to heat the water in the spa system to a desired temperature. From that information, the heating rate of the spa system can be determined, and the heating element of the spa system can be activated at the proper time to raise the temperature of the water to a selected temperature by a desired time. The spa system also monitors information which might show errors in the operation of the spa system such as a blockage in the flow of water over the heating element in the spa system.