公开(公告)号：US20060289360A1

公开(公告)日：2006-12-28

申请号：US11455726

申请日：2006-06-20

Applicant: Annalisa Delnevo ,  Carlo Lodi

Inventor： Annalisa Delnevo ,  Carlo Lodi

IPC: C02F1/00

CPC classification number: A61M1/367 ,  A61M1/3653 ,  A61M1/3656 ,  A61M1/3669 ,  A61M5/16831 ,  A61M2039/1005 ,  A61M2205/12

Abstract: A blood circuit for a dialysis machine is made from plastic material and is provided with a metallic plate, which is applied to an external face of the blood circuit and is connectable to a voltage generator in such a way as to form a capacitor, in which the plate and the blood act as the capacitor plates and the plastic material acts as the dielectric.

Abstract translation: 用于透析机的血液回路由塑料制成，并设置有金属板，该金属板被施加到血液回路的外表面，并且可以以形成电容器的方式连接到电压发生器，其中 板和血液充当电容器板，塑料材料用作电介质。

公开(公告)号：US07060047B2

公开(公告)日：2006-06-13

申请号：US10344721

申请日：2002-05-30

Applicant: Carlo Alberto Lodi ,  Francesco Paolini ,  Enrico Canini

Inventor： Carlo Alberto Lodi ,  Francesco Paolini ,  Enrico Canini

IPC: A61M37/00 ,  C02F1/44

CPC classification number: A61M1/367 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3656 ,  A61M1/3669 ,  A61M5/16831 ,  A61M2039/1005 ,  A61M2205/12

Abstract: A method of sensing the detachment of the venous needle (13) from a patient (P) during an extracorporeal blood treatment in a dialysis machine (1) having an extracorporeal blood circuit (2), in which an electric current is made to flow along a closed-loop path (P1) of an electrical circuit (37) formed by an electrical line (21, 22, 23) external to the extracorporeal circuit (2), a portion of extracorporeal circuit (2) directly connected to the venous needle (13), and the patient (P); a signal correlated with the electric current along the electrical line (21, 22, 23) is detected; and the signal is compared with a threshold value by means of a control unit (15).

Abstract translation: 一种在具有体外血液循环（2）的透析机（1）中感测在体外血液处理期间从患者（P）脱离静脉针（13）的方法，其中使电流流动 由体外电路（2）外部的电线（21,22,23）形成的电路（37）的闭环路径（P1），直接连接到静脉的体外电路（2）的一部分 针（13）和患者（P）; 检测与沿着电线（21,22,23）的电流相关的信号; 并且通过控制单元（15）将信号与阈值进行比较。

公开(公告)号：US20060116623A1

公开(公告)日：2006-06-01

申请号：US11331609

申请日：2006-01-16

Applicant: James Han ,  Thomas Hartranft ,  Thomas Kelly ,  Angel Lasso

Inventor： James Han ,  Thomas Hartranft ,  Thomas Kelly ,  Angel Lasso

IPC: A61M37/00

CPC classification number: A61M1/3669 ,  A61M1/30 ,  A61M1/3653 ,  A61M1/3656 ,  A61M1/3659 ,  A61M1/3661 ,  A61M2205/13 ,  Y10S439/909

Abstract: An extracorporeal blood system includes: (i) an extracorporeal blood machine; an extracorporeal blood circuit coupled operably to the machine, the extracorporeal blood circuit including first and second blood lines, the blood lines configured to be in blood flow communication with a patient; (ii) an electrical loop including first and second electrodes placed in contact with blood flowing through the extracorporeal blood circuit; (iii) a device configured to inject an electrical signal into the blood circuit via the loop; and (iv) a third electrode placed in contact with blood flowing through the extracorporeal blood circuit, the third electrode configured to enable a change in an electrical value to be measured so that an access disconnection of the extracorporeal blood circuit from the patient can be measured.

Abstract translation: 体外血液系统包括：（i）体外血液机器; 体外血液循环，其可操作地耦合到所述机器，所述体外血液回路包括第一和第二血液线，所述血液线被配置为与患者血液流通; （ii）电回路，其包括与流过所述体外血液回路的血液接触的第一和第二电极; （iii）被配置为经由环路将电信号注入到血液回路中的装置; 以及（iv）与流过所述体外血液回路的血液接触的第三电极，所述第三电极被配置为能够测量要测量的电值的变化，从而可以测量体外血液回路与患者的通路断开 。

公开(公告)号：US06966979B2

公开(公告)日：2005-11-22

申请号：US10772340

申请日：2004-02-06

Applicant: Renato Pedrazzi

Inventor： Renato Pedrazzi

IPC: A61M1/16 ,  A61M1/34 ,  A61M1/36 ,  A61M39/28 ,  B01D61/00 ,  B01D65/00

CPC classification number: A61M1/342 ,  A61M1/1607 ,  A61M1/1609 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3669 ,  A61M39/28 ,  A61M2230/30

Abstract: An infusion control device controls infusion of a liquid in an extracorporeal blood circuit having an arterial pipe connected to an inlet of a blood compartment of a filter and a venous pipe connected to an outlet of the blood compartment. The arterial pipe is also connected to a pre-dilution pipe of an infusion circuit, and the venous pipe is also connected to a post-dilution pipe of said infusion circuit. The infusion control device regulates and distributes an infusion flow rate in the arterial and venous pipes based on a monitoring of quantities that are directly correlated with the operating conditions of the filter.

Abstract translation: 输液控制装置控制在体外血液循环中的液体输注，其具有连接到过滤器的血液室的入口的动脉管和连接到血液室的出口的静脉管。 动脉管还连接到输注电路的预稀释管，静脉管也连接到所述输注电路的后稀释管。 输液控制装置基于与过滤器的操作条件直接相关的量的监测来调节和分配动脉和静脉管中的输注流速。

公开(公告)号：US20050178732A1

公开(公告)日：2005-08-18

申请号：US11104947

申请日：2005-04-13

Applicant: Nikolai Krivitski ,  David MacGibbon

Inventor： Nikolai Krivitski ,  David MacGibbon

IPC: A61B5/0275 ,  A61M1/16 ,  A61M1/36 ,  C02F1/00 ,  G01F1/00

CPC classification number: A61M1/3653 ,  A61B5/0275 ,  A61M1/16 ,  A61M1/3655 ,  A61M1/3658 ,  A61M1/3663 ,  A61M1/3669 ,  A61M1/367

Abstract: The measurement of blood flow in a dialysis shunt is obtained by injection of an indicator material into a venous line leading from dialysis equipment to the shunt. The blood flow in an arterial line leading from the shunt at a location downstream of the venous line to the dialysis equipment is monitored by an arterial line sensor for the presence of the indicator material. A detector connected to the sensor provides a dilution curve in response to the presence of the indicator material and the blood flow in the shunt is calculated from the area under the dilution curve. The locations of the arterial and venous lines in the shunt can be reversed to obtain a measurement of blood recirculation from the venous line into the arterial line.

Abstract translation: 通过将指示剂材料注射到从透析设备引导到分流器的静脉管线中，可以测量透析分流器中的血流量。 通过动脉线传感器监测从静脉线下游位置到分离设备的分流处的动脉线中的血液流动，以指示物质的存在。 连接到传感器的检测器响应于指示剂材料的存在而提供稀释曲线，并且根据稀释曲线下的面积计算分流器中的血流量。 分流器中的动脉和静脉线的位置可以反转，以获得从静脉线进入动脉线的血液再循环的测量。

公开(公告)号：US06912917B2

公开(公告)日：2005-07-05

申请号：US10630004

申请日：2003-07-29

Applicant: James M. Brugger ,  George W. Buffaloe, IV ,  Francis T. Ogawa

Inventor： James M. Brugger ,  George W. Buffaloe, IV ,  Francis T. Ogawa

IPC: A61M1/16 ,  A61M1/36 ,  G01F1/704 ,  G01F1/708 ,  G01N27/02 ,  G01N33/487 ,  G01F1/56 ,  G01N27/00

CPC classification number: A61M1/16 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3658 ,  A61M1/3659 ,  A61M1/3661 ,  A61M1/3669 ,  G01F1/7046 ,  G01F1/708 ,  G01F1/7088

Abstract: Methods and apparatuses for determining a fluid parameter in a vessel by altering a property of the fluid, sensing the difference in the property after the fluid is altered, particularly as related to the property in an unaltered portion of the fluid.

Abstract translation: 用于通过改变流体的性质来确定容器中的流体参数的方法和装置，感测流体改变后特性的差异，特别是与流体的未改变部分中的性质有关。

公开(公告)号：US20030176829A1

公开(公告)日：2003-09-18

申请号：US10344721

申请日：2003-02-14

Inventor： Carlo Alberto Lodi ,  Paolini Francesco ,  Enrico Canini

IPC: A61M037/00

CPC classification number: A61M1/367 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3656 ,  A61M1/3669 ,  A61M5/16831 ,  A61M2039/1005 ,  A61M2205/12

Abstract: A method of sensing the detachment of the venous needle (13) from a patient (P) during an extracorporeal blood treatment in a dialysis machine (1) having an extracorporeal blood circuit (2), in which an electric current is made to flow along a closed-loop path (P1) of an electrical circuit (37) formed by an electrical line (21, 22, 23) external to the extracorporeal circuit (2), a portion of extracorporeal circuit (2) directly connected to the venous needle (13), and the patient (P); a signal correlated with the electric current along the electrical line (21, 22, 23) is detected; and the signal is compared with a threshold value by means of a control unit (15).

Abstract translation: 一种在具有体外血液循环（2）的透析机（1）中感测在体外血液处理期间从患者（P）脱离静脉针（13）的方法，其中使电流流动 由体外回路（2）外部的电线（21,22,23）形成的电路（37）的闭环路径（P1），直接连接到静脉针的体外回路（2）的一部分 （13）和患者（P）; 检测与沿着电线（21,22,23）的电流相关的信号; 并且通过控制单元（15）将信号与阈值进行比较。

公开(公告)号：US06614212B2

公开(公告)日：2003-09-02

申请号：US10238164

申请日：2002-09-10

Applicant: James M. Brugger ,  George W. Buffaloe, IV ,  Francis T. Ogawa

Inventor： James M. Brugger ,  George W. Buffaloe, IV ,  Francis T. Ogawa

IPC: G01N2700

CPC classification number: A61M1/16 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3658 ,  A61M1/3659 ,  A61M1/3661 ,  A61M1/3669 ,  G01F1/7046 ,  G01F1/708 ,  G01F1/7088

Abstract: Method and apparatus for quantitatively determining a degree of recirculalion flow in a vessel of a fluid by altering the electrical conductivity of the fluid, sensing the difference in electromagnetic field after the fluid is altered, and integrating the sensed difference over a period of time including any time of potential recirculation of any altered conductivity fluid.

Abstract translation: 用于通过改变流体的电导率来定量地确定流体容器中的再循环流程的程度和装置，检测流体改变后电磁场的差异，以及在一段时间内积分感测的差异，包括任何 任何改变的导电液体的潜在再循环的时间。

公开(公告)号：US20030016002A1

公开(公告)日：2003-01-23

申请号：US10238164

申请日：2002-09-10

Inventor： James M. Brugger ,  George W. Buffaloe IV ,  Francis T. Ogawa

IPC: G01N027/00

CPC classification number: A61M1/16 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3658 ,  A61M1/3659 ,  A61M1/3661 ,  A61M1/3669 ,  G01F1/7046 ,  G01F1/708 ,  G01F1/7088

Abstract: A flow rate of a fluid flowing in a tube is quantitatively determined by altering the electrical conductivity of the fluid by injection of a bolus of saline. The electrical conductivity of the altered conductivity is measured over the time it takes the altered conductivity fluid to pass a conductivity measuring location. The measured conductivity is integrated over the time it take to pass the conductivity measuring location. The integral is interpreted to determine the flow rate.

Abstract translation: 在管中流动的流体的流速通过注射大量盐水改变流体的电导率而定量地确定。 在改变的导电流体通过电导率测量位置的时间内测量改变的导电性的导电性。 测量的电导率在通过电导率测量位置所需的时间内积分。 积分被解释为确定流量。

公开(公告)号：US20020121471A1

公开(公告)日：2002-09-05

申请号：US09980864

申请日：2002-04-12

Inventor： Renato Pedrazzi

IPC: C02F001/44

CPC classification number: A61M1/342 ,  A61M1/1607 ,  A61M1/1609 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3669 ,  A61M39/28 ,  A61M2230/30

Abstract: A dialysis machine having an extracorporeal blood circuit having an arterial pipe and a venous pipe respectively connected to an inlet and an outlet of a blood compartment of a filter having a blood compartment and a dialysis liquid compartment separated by a semi-permeable membrane; means for determining a sequence of infusion of a liquid in the extracorporeal blood circuit, from at least one characteristic value (FF, TMPave, Kuf) correlated with the concentration of the blood (CE) and/or a filtration efficiency of the filter; and means for infusing the infusion solution in the arterial pipe and in the venous pipe in accordance with the determined infusion sequence.

Abstract translation: 一种具有体外血液循环的透析机，其具有动脉管和静脉管，所述静脉管分别连接到具有由半透膜隔开的血液室和透析液室的过滤器的血液室的入口和出口; 用于从与血液浓度（CE）相关的至少一个特征值（FF，TMPave，Kuf）和/或过滤器的过滤效率确定在体外血液回路中液体的输注顺序的装置; 以及用于根据确定的输注顺序将输注溶液注入动脉管和静脉管中的装置。