公开(公告)号：US20100240923A1

公开(公告)日：2010-09-23

申请号：US12743819

申请日：2007-11-29

申请人： Dietmar Haering ,  Gabi Winter ,  Arnold Schneller ,  Francesca Aulenta

发明人： Dietmar Haering ,  Gabi Winter ,  Arnold Schneller ,  Francesca Aulenta

IPC分类号： C07C69/52 ,  C12P7/62

CPC分类号： C12P7/62

摘要： A process for preparing (meth)acrylic esters (F) of hydroxy-functional aromas (A), in which at least one hydroxy-functional aroma (A) in the presence of at least one enzyme (E) is esterified with (meth)acrylic acid (S), or transesterified with at least one (meth)acrylic ester (D), the reaction in the case of the transesterification being effected in the absence of solvents.

摘要翻译： 一种制备羟基官能香料（A）的（甲基）丙烯酸酯（F）的方法，其中至少一种羟基官能香料（A）在至少一种酶（E）的存在下被（甲基） 丙烯酸（S），或与至少一种（甲基）丙烯酸酯（D）进行酯交换反应时，酯交换反应在不存在溶剂的情况下进行。

公开(公告)号：US20100234549A1

公开(公告)日：2010-09-16

申请号：US12655028

申请日：2009-12-22

申请人： Xiaoming Jin ,  Paul D. Hammesfahr

发明人： Xiaoming Jin ,  Paul D. Hammesfahr

IPC分类号： C08F120/06 ,  C07C69/52

CPC分类号： C08F222/1006 ,  C08G64/1691 ,  C08G2650/34

摘要： A composition of macrocyclic oligomer with at least one (meth)acrylate polymerizable group. A method includes preparing an activated precursor of an oligomer at pseudo high-dilution conditions. A method also includes preparing an activated precursor of an oligomer by reacting the precursor with an activated coupling agent, wherein the precursor is condensable and polymerizable.

摘要翻译： 具有至少一个（甲基）丙烯酸酯可聚合基团的大环低聚物的组合物。 一种方法包括在假高稀释条件下制备低聚物的活化前体。 方法还包括通过使前体与活化的偶联剂反应来制备低聚物的活化前体，其中前体是可冷凝和可聚合的。

公开(公告)号：US20100217006A1

公开(公告)日：2010-08-26

申请号：US12675129

申请日：2008-09-01

申请人： Jiro Takata ,  Kenichi Mishima ,  Manabu Nakashima ,  Katsunori Iwasaki ,  Kazuhisa Matsunaga ,  Yoshiharu Karube ,  Michihiro Fujiwara

发明人： Jiro Takata ,  Kenichi Mishima ,  Manabu Nakashima ,  Katsunori Iwasaki ,  Kazuhisa Matsunaga ,  Yoshiharu Karube ,  Michihiro Fujiwara

IPC分类号： C07D213/79 ,  C07C69/52

CPC分类号： C07C229/12 ,  C07C229/08 ,  C07C271/22 ,  C07D311/72 ,  C07F9/65522

摘要： It is intended to provide a drug which is efficacious in treating and preventing diseases wherein ischemia or an inflammatory substance associated with ischemia participates in the onset or worsening thereof. Because of containing as the active ingredient a substance selected from among farnesol, a farnesol derivative, a tocopherol derivative, a tocotrienol derivative, pharmacologically acceptable salts thereof and solvates thereof, the above-described inhibitor of ischemic disorders can exert therapeutic and preventive effects on diseases wherein ischemia or an inflammatory substance associated with ischemia participates in the onset or worsening thereof (for example, brain infarction, brain edema, cardiac infarction, etc.) not only by the administration in the acute ischemic stage but also by the therapeutic administration in subacute and/or chronic stages after ischemia-reperfusion. It is also intended to provide a farnesol carboxylic acid ester derivative and a method of producing the same.

摘要翻译： 旨在提供一种有效治疗和预防与缺血相关的缺血或炎性物质参与其发作或恶化的疾病的药物。 由于含有选自法呢醇，法呢醇衍生物，生育酚衍生物，生育三烯酚衍生物，其药理学上可接受的盐和溶剂化物的物质作为活性成分，所以上述缺血性疾病抑制剂可以对疾病起到治疗和预防作用 其中缺血或与缺血相关的炎性物质不仅通过在急性缺血阶段的给药而且通过亚急性的治疗性给药参与其发作或恶化（例如脑梗塞，脑水肿，心肌梗死等） 和/或缺血再灌注后的慢性期。 还提供法呢醇羧酸酯衍生物及其制备方法。

公开(公告)号：US20100179262A1

公开(公告)日：2010-07-15

申请号：US12602877

申请日：2008-06-06

申请人： Rudolf J. Dams ,  Miguel A. Guerra ,  Klaus Hintzer ,  Michael Jürgens ,  Harald Kaspar ,  Kai H. Lochhaas ,  Andreas R. Maurer ,  Zai-Ming Qiu ,  Worner Schwertfeger ,  Michael S. Terrazas ,  Tilman C. Zipplies

发明人： Rudolf J. Dams ,  Miguel A. Guerra ,  Klaus Hintzer ,  Michael Jürgens ,  Harald Kaspar ,  Kai H. Lochhaas ,  Andreas R. Maurer ,  Zai-Ming Qiu ,  Worner Schwertfeger ,  Michael S. Terrazas ,  Tilman C. Zipplies

IPC分类号： C07C69/52 ,  C08K5/10 ,  C09K3/00 ,  C07F7/08

CPC分类号： C08F220/24 ,  C08F220/28 ,  C08F220/36 ,  C08F230/08 ,  C08G65/007 ,  C08L33/08 ,  C08L35/06 ,  C09D133/08 ,  C09D133/14 ,  C09D135/06 ,  C08L2666/04

摘要： A composition including at least one first divalent unit represented by formula: Each Rf is independently selected from the group consisting of Rfa—(O)t—CHF—(CF2)n—; [Rfa—(O)t—C(L)H—CF2—O]m—W—; Rfb-O—(CF2)p-; F(CkF2k)—(O—CkF2k)P—O—CF2—; and CF3—O—(CF2)3—(OCF(CF3)—CF2)Z—O-L1-. Each Q is independently selected from the group consisting of a bond, —C(O)—N(R1)—, and —C(O)—O—. Each X is independently selected from the group consisting of alkylene and arylalkylene, wherein alkylene and arylalkylene are each optionally interrupted by at least one ether linkage and optionally terminated by —N(R1)—C(O)— or —O—C(O)—. R and R1 are each independently selected from the group consisting of hydrogen and alkyl having from 1 to 4 carbon atoms. Rfa represents a partially or fully fluorinated alkyl group having from 1 to 10 carbon atoms and optionally interrupted with at least one oxygen atom. Rfb is selected from the group consisting of CF3CFH— and F(CjF2j)-. Methods of reducing surface tension of a liquid, making foams, and treating a surface using the compositions are also disclosed.

摘要翻译： 包含至少一个由式表示的第一二价单元的组合物：每个Rf独立地选自Rfa-（O）t-CHF-（CF 2）n - ; [Rfa-（O）t -C（L）H-CF 2 -O] m -W-; Rfb-O-（CF2）p-; F（CkF2k） - （O-CkF2k）P-O-CF2-; 和CF 3 -O-（CF 2）3 - （OCF（CF 3）-CF 2）Z-O-L 1。 每个Q独立地选自由键，-C（O）-N（R 1） - 和-C（O）-O-组成的组。 每个X独立地选自亚烷基和芳基亚烷基，其中亚烷基和芳基亚烷基各自任选地被至少一个醚键中断，并且任选被-N（R 1）-C（O） - 或-O-C（O ） - 。 R和R 1各自独立地选自氢和具有1至4个碳原子的烷基。 Rfa表示具有1至10个碳原子并且任选被至少一个氧原子中断的部分或完全氟化的烷基。 Rfb选自CF 3 CFH-和F（C 1 F 2）） - 。 还公开了降低液体的表面张力，制造泡沫和使用组合物处理表面的方法。

公开(公告)号：US07745658B2

公开(公告)日：2010-06-29

申请号：US12168342

申请日：2008-07-07

申请人： Gunter Lipowsky ,  Joachim Wulff-Doering ,  Peter Zurowski ,  Juergen Strasser

发明人： Gunter Lipowsky ,  Joachim Wulff-Doering ,  Peter Zurowski ,  Juergen Strasser

IPC分类号： C07C69/52

CPC分类号： C07C67/54 ,  C07C67/04 ,  C07C67/62 ,  C07C69/54

摘要： The present invention relates to a process for preparing tertiary alkyl esters of (meth)acrylic acid having at least 4 carbon atoms in the alkyl radical. The process includes reacting (meth)acrylic acid with at least one olefin of formula (I) in homogeneous phase in the presence of an acidic catalyst in a reactor, discharging the resulting reaction mixture from the reactor, separating the discharged reaction mixture into a first mixture which contains the catalyst and a second mixture which contains the tertiary alkyl ester of (meth)acrylic acid having at least 4 carbon atoms in the alkyl radical, and removing the tertiary alkyl ester of (meth)acrylic acid having at least 4 carbon atoms in the alkyl radical from the second mixture in the presence of compound S, which comprises at least one N-oxyl group and is added as a stabilizer.

摘要翻译： 本发明涉及在烷基中具有至少4个碳原子的（甲基）丙烯酸的叔烷基酯的制备方法。 该方法包括在反应器中在酸性催化剂存在下使（甲基）丙烯酸与至少一种式（I）烯烃均匀相反应，将所得反应混合物从反应器中排出，将排出的反应混合物分离成第一 包含催化剂的混合物和含有烷基中具有至少4个碳原子的（甲基）丙烯酸叔烷基酯的第二混合物，并且除去具有至少4个碳原子的（甲基）丙烯酸的叔烷基酯 在包含至少一个N-氧基并且作为稳定剂加入的化合物S的存在下，来自第二混合物的烷基。

公开(公告)号：US20100087615A1

公开(公告)日：2010-04-08

申请号：US12586146

申请日：2009-09-17

申请人： Scott Han ,  Daniel J. Martenak ,  Lei Jin ,  Steven Lawrence Suib

发明人： Scott Han ,  Daniel J. Martenak ,  Lei Jin ,  Steven Lawrence Suib

IPC分类号： C07C67/38 ,  C09K3/00 ,  C07C69/52 ,  C08F120/18 ,  C07C45/28

CPC分类号： C07C5/42 ,  C07C45/50 ,  C07C45/75 ,  C07C67/343 ,  C07C67/38 ,  C07C2529/04 ,  Y02P20/52 ,  C07C11/04 ,  C07C47/02 ,  C07C47/22 ,  C07C69/54 ,  C07C69/24

摘要： A method for producing a mixture of ethylene and carbon monoxide by contacting ethane and an oxygen source with a catalyst comprising synthetic cryptomelane or octahedral molecular sieve. The method further comprises condensing the alkyl propionate with formaldehyde to produce an alkyl methacrylate.

公开(公告)号：US20100075256A1

公开(公告)日：2010-03-25

申请号：US12321111

申请日：2009-01-15

申请人： Hyun-Sang Joo ,  Joo-Hyeon Park ,  Jung-Hoon Oh ,  Dae-Hyeon Shin

发明人： Hyun-Sang Joo ,  Joo-Hyeon Park ,  Jung-Hoon Oh ,  Dae-Hyeon Shin

IPC分类号： G03F7/004 ,  C07C69/52 ,  C07D333/02 ,  C08F14/18 ,  G03F7/20

CPC分类号： C07C381/12 ,  C07C309/12 ,  C08F20/38 ,  G03F7/0045 ,  G03F7/0046 ,  G03F7/0397 ,  Y10S430/106 ,  Y10S430/111

摘要： A compound represented by the following formula (1) is provided: wherein R1 represents a hydrogen atom, a trifluoromethyl group, an alkyl group, or an alkoxy group; and A represents a group represented by the following formula (2) or formula (3): wherein R2, R3, R4, R5 and R6 each independently represent a substituted or unsubstituted alkyl group, a substituted or unsubstituted allyl group, a substituted or unsubstituted perfluoroalkyl group, a substituted or unsubstituted benzyl group, or a substituted or unsubstituted aryl group; and two or more of R2, R3 and R4 may be linked to each other to form a saturated or unsaturated carbon ring or a saturated or unsaturated heterocyclic ring.The chemically amplified resist composition comprising a polymer compound which is produced from the compound of formula 1 according to the present invention provides a chemically amplified resist sensitive to far-ultraviolet radiation, which is represented by KrF excimer laser or ArF excimer laser.

摘要翻译： 提供由下式（1）表示的化合物：其中R1表示氢原子，三氟甲基，烷基或烷氧基; A表示由下式（2）或式（3）表示的基团：其中R 2，R 3，R 4，R 5和R 6各自独立地表示取代或未取代的烷基，取代或未取代的烯丙基，取代或未取代的 取代或未取代的苄基或取代或未取代的芳基; R2，R3和R4中的两个或多个可以彼此连接形成饱和或不饱和的碳环或饱和或不饱和的杂环。 包含由根据本发明的式1化合物制备的高分子化合物的化学放大抗蚀剂组合物提供对由KrF准分子激光器或ArF准分子激光器表示的远紫外辐射敏感的化学放大抗蚀剂。

公开(公告)号：US07629383B2

公开(公告)日：2009-12-08

申请号：US10496328

申请日：2002-11-22

申请人： Jo Klaveness

发明人： Jo Klaveness

IPC分类号： A61K31/225 ,  C07C69/52

CPC分类号： A61K31/225 ,  A61K31/23 ,  C07C69/34 ,  C07C69/48 ,  C07C69/96

摘要： The invention provides acyloxymethyl esters of C6-14 alkane-dicarboxylic acids, or physiologically tolerable salts or esters thereof, for use in medicine as therapeutic or prophylactic agents.

摘要翻译： 本发明提供了用作医药或预防药物的C 6-14烷烃二羧酸的酰氧基甲基酯或其生理上可耐受的盐或酯。

公开(公告)号：US20090270396A1

公开(公告)日：2009-10-29

申请号：US12427469

申请日：2009-04-21

申请人： David W. Old ,  Vinh X. Ngo

发明人： David W. Old ,  Vinh X. Ngo

IPC分类号： A61K31/5375 ,  C07C69/52 ,  A61K31/215 ,  C07D265/30 ,  A61P17/14

CPC分类号： C07C59/90 ,  C07B2200/07 ,  C07C57/62 ,  C07C59/86 ,  C07C69/732 ,  C07C255/46 ,  C07C255/57 ,  C07C325/02 ,  C07C405/00 ,  C07C2601/08 ,  C07C2601/10 ,  C07C2602/24 ,  C07C2602/26 ,  C07D213/30 ,  C07D213/55 ,  C07D213/57 ,  C07D213/61 ,  C07D215/14 ,  C07D277/56 ,  C07D295/088 ,  C07D307/68 ,  C07D307/80 ,  C07D333/16 ,  C07D333/24 ,  C07D333/62 ,  C07D405/12 ,  C07D409/08 ,  C07D409/12 ,  C07D417/08 ,  C07F9/3834 ,  C07F9/58 ,  Y10S514/88

摘要： Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein J1, J2, U1, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed.

摘要翻译： 公开了包含其药学上可接受的盐或其前药的化合物，其中J1，J2，U1，B，Y和A如上所述。 还公开了与之相关的方法，组合物和药物。

公开(公告)号：US20090264672A1

公开(公告)日：2009-10-22

申请号：US12422096

申请日：2009-04-10

申请人： Timothy W. Abraham ,  Hiroki Kaido ,  Choon Woo Lee ,  Richard L. Pederson ,  Yann Schrodi ,  Michael John Tupy

发明人： Timothy W. Abraham ,  Hiroki Kaido ,  Choon Woo Lee ,  Richard L. Pederson ,  Yann Schrodi ,  Michael John Tupy

IPC分类号： C07C69/52 ,  C07C57/13

CPC分类号： C07C67/475 ,  B01J31/2265 ,  B01J31/2278 ,  B01J2231/543 ,  B01J2531/821 ,  C07C6/04 ,  C07C67/02 ,  C07C67/303 ,  C07C67/307 ,  C07C67/31 ,  C07C67/333 ,  C07C2531/22 ,  C07C2531/24 ,  C07F7/1884 ,  C07C11/02 ,  C07C69/65 ,  C07C69/734 ,  C07C69/533 ,  C07C69/593 ,  C07C69/73

摘要： Described are methods of making organic compounds by metathesis chemistry. The methods of the invention are particularly useful for making industrially-important organic compounds beginning with starting compositions derived from renewable feedstocks, such as natural oils. The methods make use of a cross-metathesis step with an olefin compound to produce functionalized alkene intermediates having a pre-determined double bond position. Once isolated, the functionalized alkene intermediate can be self-metathesized or cross-metathesized (e.g., with a second functionalized alkene) to produce the desired organic compound or a precursor thereto. The method may be used to make bifunctional organic compounds, such as diacids, diesters, dicarboxylate salts, acid/esters, acid/amines, acid/alcohols, acid/aldehydes, acid/ketones, acid/halides, acid/nitriles, ester/amines, ester/alcohols, ester/aldehydes, ester/ketones, ester/halides, ester/nitriles, and the like.

摘要翻译： 描述的是通过复分解化学制备有机化合物的方法。 本发明的方法特别可用于制备工业上重要的有机化合物，起始于可再生原料如天然油的组合物。 该方法利用与烯烃化合物的交叉复分解步骤来制备具有预定双键位置的官能化烯烃中间体。 一旦分离，官能化的烯烃中间体可以是自我化的或交叉的（例如用第二官能化的烯烃）产生所需的有机化合物或其前体。 该方法可用于制备双官能有机化合物，例如二酸，二酯，二羧酸盐，酸/酯，酸/胺，酸/醇，酸/醛，酸/酮，酸/卤化物，酸/腈，酯/ 胺，酯/醇，酯/醛，酯/酮，酯/卤化物，酯/腈等。